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| 1 | Coherent beam combining of high powerfiber lasers: Progress and prospect显示文摘The recent research progress of coherent beam combining of high power fiber lasers is reviewed. Key technologies like coherently combinable fiber laser, phase control of multiple beams and beam tilling are specially analyzed. Prospects for single coherently combinable high power fiber amplifier, beam tilling and target-in-the-loop control for propagation in real atmosphere are presented. | LIU ZeJin ZHOU Pu XU XiaoJun WANG XiaoLin MA YanXing | 2013 | Science China(Technological Sciences)2013，56，7： | 16 |
| 2 | High power all-fiberized and narrow-bandwidth MOPA system by tandem pumping strategy for thermally induced mode instability suppression显示文摘An all-fiberized and narrow-bandwidth master oscillator power amplification(MOPA) system with record output power of 4 kW level and slope efficiency of 78% is demonstrated. Tandem pumping strategy is tentatively introduced into the narrow-bandwidth MOPA system for thermally induced mode instability(TMI) suppression. The stimulated Brillouin scattering(SBS) effect is balanced by simply using one-stage phase modulation technique. With different phase modulation signals, SBS limited output powers of 336 W, 1.2 kW and 3.94 kW are respectively achieved with spectral bandwidths accounting for 90% power of ~0.025, 0.17 and ~0.89 nm. Compared with our previous 976 nm pumping system, TMI threshold is overall boosted to be >5 times in which tandem pumping increases the TMI threshold of >3times. The beam quality(M~2 factor) of the output laser is well within 1.5 below the TMI threshold while it is ultimately saturated to be 1.86 with the influence of TMI at maximal output power. Except for SBS and TMI, stimulated Raman scattering(SRS) effect will be another challenge for further power scaling. In such a high power MOPA system, multidetrimental effects(SBS, SRS and TMI) will coexist and may be mutual-coupled, which could provide a well platform for further comprehensively investigating and optimizing the high power, narrow-bandwidth fiber amplifiers. | Pengfei Ma Hu Xiao Daren Meng Wei Liu Rumao Tao Jinyong Leng Yanxing Ma Rongtao Su Pu Zhou Zejin Liu | 2018 | High Power Laser Science and Engineering2018，6，4： | 9 |
| 3 | A highly potent and stable pan-coronavirus fusion inhibitor as a candidate prophylactic and therapeutic for COVID-19 and other coronavirus diseases显示文摘The development of broad-spectrum antivirals against human coronaviruses(HCoVs)is critical to combat the current coronavirus disease 2019(COVID-19)pandemic caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)and its variants,as well as future outbreaks of emerging CoVs.We have previously identified a polyethylene glycol-conjugated(PEGylated)lipopeptide,EK1C4,with potent pan-CoV fusion inhibitory activity.However,PEG linkers in peptide or protein drugs may reduce stability or induce anti-PEG antibodies in vivo.Therefore,we herein report the design and synthesis of a series of dePEGylated lipopeptide-based pan-CoV fusion inhibitors featuring the replacement of the PEG linker with amino acids in the heptad repeat 2 C-terminal fragment(HR2-CF)of HCoV-OC43.Among these lipopeptides,EKL1C showed the most potent inhibitory activity against infection by SARS-CoV-2 and its spike(S)mutants,as well as other HCoVs and some bat SARS-related coronaviruses(SARSr-CoVs)tested.The dePEGylated lipopeptide EKL1C exhibited significantly stronger resistance to proteolytic enzymes,better metabolic stability in mouse serum,higher thermostability than the PEGylated lipopeptide EK1C4,suggesting that EKL1C could be further developed as a candidate prophylactic and therapeutic for COVID-19 and other coronavirus diseases. | Jie Zhou Wei Xu Zezhong Liu Chao Wang Shuai Xia Qiaoshuai Lan Yanxing Cai Shan Su Jing Pu Lixiao Xing Youhua Xie Lu Lu Shibo Jiang Qian Wang | 2022 | Acta Pharmaceutica Sinica B2022，12，4： | 5 |
| 4 | Impacts of river impoundment on the riverine water chemistry composition and their response to chemical weathering rate显示文摘当前,世界范围的大多数河强烈地被扣押了。河建水坝成为一个大问题,不是仅仅在导致物理阻塞在之间在上游并且下游地,而且在里面破坏河的自然连续性。但是水质量的断绝是经常忽视了研究,它介绍挑战给传统的河地球化学。在水坝在上游、下游的水的基本化学理解变化,我们在 Wujiang 河盆,和 Hongjiadu 在系列调查了 Miaotiao 河水库, Wujiang 河的上面的活动范围上的 Dongfeng 水库。化学捱过率分别地用水坝的水库表面并且下游地的水化学数据是计算的,在每座水库。结果证明捱过率的化学药品之间的差别从水库表面水计算了,水坝下游的水在有一更长的水保留时间的水库是更大的。在有在学习水库之中的最长的水保留时间的 Hongjiadu 水库,这差别到达 9% 。作为结果,河建水坝的影响,特别在系列的水库的影响,当计算河盆的化学捱过率时,应该被考虑[出版摘要] | Yang GAO Baoli WANG Xiaolong LIU Yuchun WANG Jing ZHANG Yanxing JIANG | 2013 | Frontiers of Earth Science2013，7，3： | 3 |
| 5 | Early changes to the extracellular space in the hippocampus under simulated microgravity conditions显示文摘The smooth transportation of substances through the brain extracellular space(ECS)is crucial to maintaining brain function;however,the way this occurs under simulated microgravity remains unclear.In this study,tracer-based magnetic resonance imaging(MRI)and DECS-mapping techniques were used to image the drainage of brain interstitial fluid(ISF)from the ECS of the hippocampus in a tail-suspended hindlimb-unloading rat model at day 3(HU-3)and 7(HU-7).The results indicated that drainage of the ISF was accelerated in the HU-3 group but slowed markedly in the HU-7 group.The tortuosity of the ECS decreased in the HU-3 group but increased in the HU-7 group,while the volume fraction of the ECS increased in both groups.The diffusion rate within the ECS increased in the HU-3 group and decreased in the HU-7 group.The alterations to ISF drainage and diffusion in the ECS were recoverable in the HU-3 group,but neither parameter was restored in the HU-7 group.Our findings suggest that early changes to the hippocampal ECS and ISF drainage under simulated microgravity can be detected by tracer-based MRI,providing a new perspective for studying microgravity-induced nano-scale structure abnormities and developing neuroprotective approaches involving the brain ECS. | Yajuan Gao Hongbin Han Jichen Du Qingyuan He Yanxing Jia Junhao Yan Hui Dai Bin Cui Jing Yang Xunbin Wei Liu Yang Rui Wang Ren Long Qiushi Ren Xing Yang Jiabin Lu | 2022 | Science China(Life Sciences)2022，65，3： | 2 |
| 6 | Auditory deprivation modifies the expression of brain-derived neurotrophic factor and tropomyosin receptor kinase B in the rat auditory cortex显示文摘The development and plasticity of central auditory system can be influenced by the change of peripheral neuronal activity. However, the molecular mechanism participating in the process remains elusive. Brain-derived neurotrophic factor(BDNF) binding with its functional receptor tropomyosin receptor kinase B(TrkB) has multiple effects on neurons. Here we used a rat model of auditory deprivation by bilateral cochlear ablation, to investigate the changes in expression of BDNF and Trk B in the auditory cortex after auditory deprivation that occurred during the critical period for the development of central auditory system. Reverse transcription-quantitative polymerase chain reaction(RTqPCR) and immunohistochemistry methods were adopted to detect the m RNA and protein expression levels of BDNF and TrkB in the auditory cortex at 2, 4, 6 and 8 weeks after surgery, respectively. The change in the expression of BDNF and TrkB mRNAs and proteins followed similar trend. In the bilateral cochlear ablation groups, the BDNF-TrkB expression level initially decreased at 2 weeks but increased at 4 weeks followed by the reduction at 6 and 8 weeks after cochlear removal, as compared to the age-matched sham control groups. In conclusion, the BDNF-TrkB signaling is involved in the plasticity of auditory cortex in an activity-dependent manner. | Yuxing Wang Ou Xu Yanxing Liu Hong Lu | 2017 | Journal of Otology2017，12，1： | 2 |
| 7 | Progress of study on upconversion materials and its application on laser technology显示文摘 | ZANG JINGCUN LIU YANXING | 1996 | High Technology Letters1996，3，： | 1 |
| 8 | Structural optimization and evaluation of butenolides as potent antifouling agents: modification of the side chain affects the biological activities of compounds显示文摘 | Yongxin Li Fengying Zhang Ying Xu Kiyotaka Matsumura Zhuang Han Lingli Liu Wenhan Lin Yanxing Jia Pei-Yuan Qian | 2012 | Biofouling2012，，8： | 1 |
| 9 | Application of feature - weighted support vector regression using grey correlation degree to stock price forecast - ing显示文摘 | James NK Liu Yanxing Hu | 2013 | Neural Comput Applic2013，22，1： | 1 |
| 10 | Preparation and self-assembly of chitosan/carbon microsphere composite显示文摘 | Yongzhen Yang Yanxing Han Xuguang Liu Bingshe Xu | 2012 | Journal of Wuhan University of Technology-Mater Sci Ed2012，，3： | 1 |
| 11 | Application of feature-weighted Support Vector regression using grey correlation degree to stock price forecasting显示文摘 | James N. K. Liu Yanxing Hu | 2013 | Neural Computing and Applications2013，，1： | 1 |
| 12 | Experience inheritance from famous specialists based on real- world clinical research paradigm of traditional Chinese medicine显示文摘从在繁体中文药(TCM ) 的著名专家的经验继承的当前的模式包括主人和门徙,文学评论, clinical-epidemiology-based 临床的研究观察和经由计算机和数据库技术的数据采矿。每个模式有它的优点和劣势。然而,一个科学、有启发性的经验继承模式没被开发。大数据时代以及形成和在真实世界上的 TCM 临床的研究范例的实践累积的来临为从著名 TCM 专家继承经验提供了新观点,技术,和方法。通过连续探索和实践,研究组基于真实世界的 TCM 临床的研究范例建议革新研究模式,它包含存在模式的继承和革新。这个模式与它 TCM 的自己的发展整齐一致被提出并且被期望在临床的领域里成为经验继承的主要模式。 | Guanli Song Yinghui Wang Runshun Zhang Baoyan Liu Xuezhong Zhou Xiaji Zhou Hong Zhang Yufeng Guo Yanxing Xue Lili Xu | 2014 | Frontiers of Medicine2014，8，3： | 1 |
| 13 | Adsorption characteristics of crocin in the extract of gardenia fruits (Gardeniajasminoides Ellis) on macroporous resins显示文摘 | YANG Bin GAO Yanxing LIU Xuan | 2009 | Journal of Food Process Engineering2009，32，1： | 1 |
| 14 | Synthesis and selective gas-sensing properties of hierarchically porous intestine-like SnO2 hollow nanostructures 显示文摘 | Liu Shunqiang Xie Mingjiang Li Yanxing Guo Xuefeng Ji Weijie Ding Weiping | | Materials Chemistry and Physics 2 0100，123，： | 1 |
| 15 | Data Matching of Solar Images Super-Resolution Based on Deep Learning显示文摘The images captured by different observation station have different resolutions.The Helioseismic and Magnetic Imager(HMI:a part of the NASA Solar Dynamics Observatory SDO)has low-precision but wide coverage.And the Goode Solar Telescope(GST,formerly known as the New Solar Telescope)at Big Bear Solar Observatory(BBSO)solar images has high precision but small coverage.The super-resolution can make the captured images become clearer,so it is wildly used in solar image processing.The traditional super-resolution methods,such as interpolation,often use single image’s feature to improve the image’s quality.The methods based on deep learning-based super-resolution image reconstruction algorithms have better quality,but small-scale features often become ambiguous.To solve this problem,a transitional amplification network structure is proposed.The network can use the two types images relationship to make the images clear.By adding a transition image with almost no difference between the source image and the target image,the transitional amplification training procedure includes three parts:transition image acquisition,transition network training with source images and transition images,and amplification network training with transition images and target images.In addition,the traditional evaluation indicators based on structural similarity(SSIM)and peak signal-to-noise ratio(PSNR)calculate the difference in pixel values and perform poorly in cross-type image reconstruction.The method based on feature matching can effectively evaluate the similarity and clarity of features.The experimental results show that the quality index of the reconstructed image is consistent with the visual effect. | Liu Xiangchun Chen Zhan Song Wei Li Fenglei Yang Yanxing | 2021 | Computers, Materials & Continua2021，，9： | 0 |
| 16 | Aiphanol, a native compound, suppresses angiogenesis via dual-targeting VEGFR2 and C0X2显示文摘Dear Editor,Pathological neo-vascularization is a hallmark of cancer and several diseases.Accumulating evidence supports the notion that antiangiogenic treatment can abolish tumor angiogenesis to achieve Ion ger disease-free survival.Although growth factors and their receptors function as the main drivers in angiogenesis,the involvement of other regulators,e.g.,Cyclooxygenase-2(COX2),^(1) should also be con sidered,especially for managi ng the resista nee to therapies against receptor tyrosine kinases(RTKs). | Shanmei Chen Junnan Feng Chuanke Zhao Lixin Wang Lin Meng Caiyun Liu Shaoqing Cai Yanxing Jia Like Qu Chengchao Shou | 2022 | Signal Transduction and Targeted Therapy2022，7，1： | 0 |
| 17 | Optimizing 3d spin polarization of CoOOH by in situ Mo doping for efficient oxygen evolution reaction显示文摘Transition-metal oxyhydroxides are attractive catalysts for oxygen evolution reactions(OERs).Further studies for developing transition-metal oxyhydroxide catalysts and understanding their catalytic mechanisms will benefit their quick transition to the next catalysts.Herein,Mo-doped CoOOH was designed as a high-performance model electrocatalyst with durability for 20 h at 10 mAcm−2.Additionally,it had an overpotential of 260 mV(glassy carbon)or 215 mV(nickel foam),which was 78 mV lower than that of IrO_(2)(338 mV).In situ,Raman spectroscopy revealed the transformation process of CoOOH.Calculations using the density functional theory showed that during OER,doped Mo increased the spin-up density of states and shrank the spin-down bandgap of the 3d orbits in the reconstructed CoOOH under the electrochemical activation process,which simultaneously optimized the adsorption and electron conduction of oxygen-related intermediates on Co sites and lowered the OER overpotentials.Our research provides new insights into the methodical planning of the creation of transition-metal oxyhydroxide OER catalysts. | Zhichao Jia Yang Yuan Yanxing Zhang Xiang Lyu Chenhong Liu Xiaoli Yang Zhengyu Bai Haijiang Wang Lin Yang | 2024 | Carbon Energy2024，6，1： | 0 |
| 18 | Development Status of Grape Industry in Wuhan City and Recom-mendations显示文摘Since the beginning of grape cultivation in the 1980 s in Wuhan City,the grape industry has shown a steady growth trend. Through the survey of the local grape industry,it found out the regional distribution,scale and benefits of the grape,as well as the variety structure and cultivation management mode. It analyzed main problems in the grape production,including low degree of organization,concentrated maturity,low rate of good fruit,small cultivation scale,and low labor-saving and high-efficiency cultivation technologies. On the basis of the development status,it came up with pertinent recommendations,including optimizing the variety structure,implementing standardized management,strengthening construction of sightseeing parks,promoting integration of primary and tertiary industries,and developing the gardening experience,to promote healthy and sustainable development of the grape industry. | Changlin LI Zhi TANG Shoukun YANG Li JIN Fuyuan SU Xian PEI Xianbao LIU Xiaomei JI Aixin WANG Xubai CHEN Yanxing YAO Yang QIN Hongying LIU Yiman LIU Weidong CHEN | 2018 | Asian Agricultural Research2018，10，11： | 0 |
| 19 | Breeding and Cultivation Techniques of Fly Fire,an Elite Variety of Malus micromalus显示文摘Fly fire is an elite variety of North American Begonia( Malus micromalus),which is characterized with dark red flowers,red young leaves,red peel,red bark,large flower amount,long flowering period and long fruit bearing period. It is propagated mainly through grafting,and is suitable for popularization and application in the landscape of the Yangtze River basin and north of the Yangtze River. | Changlin LI Li JIN Fuyuan SU Yanxing YAO Xian PEI Chengxiang ZHENG Xianbao LIU Fazhi CHEN Yang QIN Hongying LIU Shoukun YANG | 2018 | Agricultural Biotechnology2018，7，3： | 0 |
| 20 | Coumarin derivative dye sensitized NaYGdF4:Yb,Er nanoparticles with enhanced NIR Ⅱ luminescence for bio-vascular imaging显示文摘Lanthanide-doped biocompatible nanoparticles have promising applications in near-infrared second region imaging due to their high chemical stability,enhanced photostability and sharp emission bandwidth.However,the weak light absorption capacity limits the application of rare-earth nanoparticles(RENPs) for bioimaging.We prepared a coumarin-derived dye sensitized NaYGdF4:Yb,Er nanoparticle probe,in which the organic dye enhances photon absorption through the sensitization process,improving the luminescence efficiency of the rare earth particles near 1000 and 1500 nm.In addition,good water solubility and stability of the probe are imparted by coating the particles with amphiphilic polymers distearoyl phosphatidylethanolamine-polyethylene glycol(DSPE-PEG) and polyacrylic acid.This composite probe with good biocompatibility and NIR Ⅱ luminescence properties can be used for vascular imaging,providing a tool for the detection of hematologic-related diseases. | Yaqun Ma Zhan Wang Yanxing Wang Zhenghao Liu Yukun Wang Ruichan Lv | 2023 | Journal of Rare Earths2023，41，12： | 0 |
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