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| 1 | Efficacy and safety of electroacupuncture in treatment of lumbar disc herniation: a protocol for a cohort study显示文摘OBJECTIVE: To compare the efficacy of electroacupuncture(deep needling) and general orthopedics in treatment of lumbar disc herniation(LDH), and to evaluate its long-term efficacy.METHODS: This trial is a prospective cohort study.A total of 175 participants will be observed. The exposure group is obtained from department of acupuncture and moxibustion and the control group is from orthopedic department in hospital. Patients in exposed group will receive electroacupuncture in Dachangshu(BL 25), Guanyuanshu(BL 26), L4 Jiaji points(EX-B2 L4), L5 Jiaji points(EX-B2 L5) and S1 Jiaji points(EX-B2 S1) in the affected side once a day, 6 times as a treatment course for two courses(12 times). Patients in control group will receive orthopedic conventional therapy. In acute period,the treatment is mannitol injection(250 mL∶50 g) 200 mL, i.v., q.d.; 0.9% sodium chloride injection250 mL, vitamin C injection 2 g, Dexamethasone sodium phosphate injection 10 mg, i.v., q.d.; sterile water for injection 2 mL, adenosine cobalt amine injection 1 mg, i.m., q.d., 12 d. In remission period,the treatment is Voltaren(Diclofenac diethyl lamine emulsion) external, q.d., 12 d. The researchers do not give any other intervention and record the relevant information only.RESULTS: Modified Japanese Orthopaedic Association Scores, Visual Analogue Scale/Score, the Short Form-36 Quality-of-Life Questionnaire and Oswestry Disability Questionnaire and the second outcome measures(Adverse Event Questionnaire and Relapse Questionnaire) are measured before treatment, after the sixth treatment, and after the twelfth treatment. The follow-up periods are3 months after the twelfth treatment, 6 months after the twelfth treatment, 1 year after the twelfth treatment.CONCLUSION: This study will provide clinical researchers with the evidence on the safety and longterm efficacy of electroacupuncture in patients with Lumbar disc herniation. | Liu Yaru Zhao Jianxin Tian Yuanxiang | 2019 | Journal of Traditional Chinese Medicine2019，39，1： | 19 |
| 2 | A nowcasting model for the prediction of typhoon tracks based on a long short term memory neural network显示文摘It is of vital importance to reduce injuries and economic losses by accurate forecasts of typhoon tracks. A huge amount of typhoon observations have been accumulated by the meteorological department, however, they are yet to be adequately utilized. It is an effective method to employ machine learning to perform forecasts. A long short term memory(LSTM) neural network is trained based on the typhoon observations during 1949–2011 in China's Mainland, combined with big data and data mining technologies, and a forecast model based on machine learning for the prediction of typhoon tracks is developed. The results show that the employed algorithm produces desirable 6–24 h nowcasting of typhoon tracks with an improved precision. | GAO Song ZHAO Peng PAN Bin LI Yaru ZHOU Min XU Jiangling ZHONG Shan SHI Zhenwei | 2018 | Acta Oceanologica Sinica2018，37，5： | 17 |
| 3 | Zebrafish model for assessing induced organ toxicity by Strychnos nux-vomica显示文摘OBJECTIVE:To assess the acute organ toxicity of Strychnos nux-vomica with zebrafish model visually.METHODS:To assess acute toxicity,we initially determined the lethal concentration after Strychnos nux-vomica treatment for 24 h.Zebrafish was treated with five concentrations Strychnos nux-≦vo LC10 for 24 h,and the effects ofmica on morphology,function of heart,central nervous system,liver,kidney and organ-specific cell death were assessed.Next,we assessed the reversibility of toxic effect.RESULTS:Strychnos nux-vomica has an effect on the different organs of zebrafish,including heart,central nervous system,liver,and kidney,and cadiotoxicity induced by Strychnos nux-vomica was reversible to some extent.CONCLUSION:Zebrafish model is suitable for confirming the toxic target organs for Chinese traditional medicine. | Zhao Chongjun Tian Jinghuan Wang Jinfeng Feng Yaru Ni Yuanyuan Fan Jiaojiao Wang Chunmei Cao Dan Zou Qinwen Ma Zhiqiang Lin Ruichao | 2016 | Journal of Traditional Chinese Medicine2016，36，4： | 9 |
| 4 | Physical processes causing the formation of hypoxia off the Changjiang estuary after Typhoon Chan-hom, 2015显示文摘Severe hypoxia was observed in the submarine canyon to the east of the Changjiang estuary in July 14, 2015, two days after typhoon Chan-hom. The oxygen concentration reached as low as 2.0 mg/L and occupied a water column of about 25 m. A ROMS model was con?gured to explore the underlying physical processes causing the formation of hypoxia. Chan-hom passed through the Changjiang estuary during the neap tide. The strati?cation was completely destroyed in the shallow nearshore region when typhoon passing. However, it was maintained in the deep canyon, though the surface mixed layer was largely deepened. The residual water in the deep canyon is considered to be the possible source of the later hypoxia. After Chan-hom departure, not only the low salinity plume water spread further of fshore, but also the sea surface temperature(SST) rewarmed quickly. Both changes helped strengthen the strati?cation and facilitate the formation of hypoxia. It was found that the surface heat ?ux, especially the solar short wave radiation dominated the surface re-warming, the of fshore advection of the warmer Changjiang Diluted Water(CDW) also played a role. In addition to the residual water in the deep canyon, the Taiwan Warm Current(TWC) was found to ?ow into the deep canyon pre-and soon post-Chan-hom, which was considered to be the original source of the hypoxia water. | GUO Yaru RONG Zengrui LI Bo XU Zhao LI Pixue LI Xiaodan | 2019 | Journal of Oceanology and Limnology2019，37，1： | 5 |
| 5 | A CuNi/C Nanosheet Array Based on a Metal–Organic Framework Derivate as a Supersensitive Non-Enzymatic Glucose Sensor显示文摘Bimetal catalysts are good alternatives for nonenzymatic glucose sensors owing to their low cost, high activity, good conductivity, and ease of fabrication. In the present study, a self-supported CuNi/C electrode prepared by electrodepositing Cu nanoparticles on a Ni-based metal–organic framework(MOF) derivate was used as a non-enzymatic glucose sensor. The porous construction and carbon scaffold inherited from the Ni-MOF guarantee good kinetics of the electrode process in electrochemical glucose detection. Furthermore, Cu nanoparticles disturb the array structure of MOF derived films and evidently enhance their electrochemical performances in glucose detection. Electrochemical measurements indicate that the CuNi/C electrode possesses a high sensitivity of17.12 mA mM^(-1) cm^(-2), a low detection limit of 66.67 nM,and a wider linearity range from 0.20 to 2.72 mM. Additionally, the electrode exhibits good reusability, reproducibility, and stability, thereby catering to the practical use of glucose sensors. Similar values of glucose concentrations in human blood serum samples are detected with our electrode and with the method involving glucose-6-phosphate dehydrogenase; the results further demonstrate the practical feasibility of our electrode. | Li Zhang Chen Ye Xu Li Yaru Ding Hongbo Liang Guangyu Zhao Yan Wang | 2018 | Nano-Micro Letters2018，10，2： | 4 |
| 6 | A bacterial effector protein uncovers a plant metabolic pathway involved in tolerance to bacterial wilt disease显示文摘Bacterial wilt caused by the soil-borne plant pathogen Ralstonia solanacearum is a devastating disease worldwide.Upon plant colonization,R.solanacearum replicates massively,causing plant wilting and death;collapsed infected tissues then serve as a source of inoculum.In this work,we show that the plant metabolic pathway mediated by pyruvate decarboxylases(PDCs)contributes to plant tolerance to bacterial wilt disease.Arabidopsis and tomato plants resp ond to R.solanacearum infection by in creasing PDC activity,and plants with deficient PDC activity are more susceptible to bacterial wilt.Treatment with either pyruvic acid or acetic acid(substrate and product of the PDC pathway,respectively)enhances plant tolerance to bacterial wilt disease.An effector protein secreted by R.solanacearum,RipAK,interacts with PDCs and inhibits their oligomerization and enzymatic activity.Collectively,our work reveals a metabolic pathway involved in plant resistance to biotic and abiotic stresses,and a bacterial virulence strategy to promote disease and the completion of the pathogenic life cycle. | Yaru Wang Achen Zhao Rafael J.L.Morcillo Gang Yu Hao Xue Jose S.Rufian Yuying Sang Alberto P.Macho | 2021 | Molecular Plant2021，14，8： | 3 |
| 7 | LncRNA NORAD promotes the progression of myocardial infarction by targeting the miR-22-3p/PTEN axis显示文摘NORAD is a newly identified long non-coding RNA(lncRNA)that plays an important role in cancers.NORAD has been found to be highly expressed in the mouse model of acute myocardial infarction(AMI).However,the role of NORAD in the regulation of AMI remains unknown.In the present study,we aimed to investigate the function of NORAD in AMI and explore the potential regulatory mechanisms.A mouse model of AMI was established and NORAD was knocked-down.The infarcted size of heart tissues and the cardiac function were evaluated.In addition,two cardiomyocyte cell lines were treated with hypoxia/re-oxygenation(H/R)to mimic AMI in vitro.Luciferase reporter assay,RNA pull-down assay,fluorescence in situ hybridization,qRT-PCR,and western blot analysis were performed.Apoptotic cells and the levels of L-lactate dehydrogenase(LDH)and malondialdehyde(MDA)were detected.Our results show that downregulation of NORAD efficiently attenuates heart damage in the AMI mouse model.NORAD interacts with miR-22-3p.Knock-down of NORAD inhibits H/R-induced cell apoptosis and reduces LDH and MDA levels,while its effects are abolished by miR-22-3p inhibitor.MiR-22-3p interacts with PTEN and inhibits its expression.Overexpression of miR-22-3p inhibits H/R-induced cell apoptosis and reduces LDH and MDA levels,while its effects are abolished by overexpression of PTEN.Finally,overexpression of NORAD inhibits the AKT/mTOR signaling pathway,and its effects are attenuated by overexpression of miR-22-3p.Taken together,our study reveals that NORAD promotes the progression of AMI by regulating the miR-22-3p/PTEN axis,and the AKT/mTOR signaling may also be involved in the regulatory processes. | Chunxia Li Lihui Zhang Xingpeng Bu Guofang Chu Xiaofang Zhao Yaru Liu | 2022 | Acta Biochimica et Biophysica Sinica2022，54，4： | 3 |
| 8 | Hydrochemical characteristics and water quality evaluation of shallow groundwater in Suxian mining area,Huaibei coalfield,China显示文摘The aim of this study is to evaluate the hydrogeochemical characteristics and water environmental quality of shallow groundwater in the Suxian mining area of Huaibei coalfield,China.The natural formation process of shallow groundwater in Suxian is explored using Piper trilinear charts and Gibbs diagrams,and by examining the ratios between the major ions.United States Salinity Laboratory(USSL)charts,Wilcox diagrams,and the water quality index(WQI)are further employed to quantify the differences in water quality.The results reveal that the main hydrochemical facies of groundwater are HC03-Ca,and that silicate dissolution is the main factor controlling the ion content in shallow groundwater.The USSL charts and Wilcox diagrams show that most of the water samples would be acceptable for use in irrigation systems.The WQI results for each water sample are compared and analyzed,and the quality of groundwater samples around collapse ponds is found to be relatively poor. | Hao Yu Herong Gui Honghai Zhao Meichen Wang Jun Li Hongxia Fang Yaqi Jiang Yaru Zhang | 2020 | International Journal of Coal Science & Technology2020，7，4： | 3 |
| 9 | Interannual Variability and Scenarios Projection of Sea Ice in Bohai Sea Part Ⅰ: Variation Characteristics and Interannual Hindcast显示文摘The Bohai Sea is one of the southernmost areas for sea ice formation in the northern hemisphere.Sea ice disasters in this body of water severely affect marine activities and the safety of coastal residents.In this study,we analyze the variation characteristics of the sea ice in the Bohai Sea and establish an annual regression model based on predictable mode analysis method.The results show the following:1)From 1970 to 2018,the average ice grade is(2.6±0.8),with a maximum of 4.5 and a minimum of 1.0.Liaodong Bay(LDB)has the heaviest ice conditions in the Bohai Sea,followed by Bohai Bay(BHB)and Laizhou Bay(LZB).Interannual variation is obvious in all three bays,but the linear decreasing trend is significant only in BHB.2)Three modes are obtained from empirical orthogonal function analysis,namely,single polarity mode with the same sign of anomaly in all of the three bays and strong interannual variability(82.0%),the north–south dipole mode with BHB and LZB showing an opposite sign of anomalies to that in LDB and strong decadal variations(14.5%),and a linear trend mode(3.5%).Critical factors are analyzed and regression equations are established for all the principal components,and then an annual hindcast model is established by synthesizing the results of the three modes.This model provides an annual spatial prediction of the sea ice in the Bohai Sea for the first time,and meets the demand of operational sea ice forecasting. | JIAO Yan HUANG Fei LIU Qingrong LI Ge LI Yaru YU Qingxi ZHAO Yiding | 2020 | Journal of Ocean University of China2020，19，2： | 2 |
| 10 | OGG1 inhibition suppresses African swine fever virus replication显示文摘African swine fever virus(ASFV)is an important pathogen that causes a highly contagious and lethal disease in swine,for which neither a vaccine nor treatment is available.The DNA repair enzyme 8-oxoguanine DNA glycosylase 1(OGG1),which excises the oxidative base lesion 8-oxo-7,8-dihydroguanine(8-oxoG),has been linked to the pathogenesis of different diseases associated with viral infections.However,the role of OGG1-base excision repair(BER)in ASFV infection has been poorly investigated.Our study aimed to characterize the alteration of host reactive oxygen species(ROS)and OGG1 and to analyse the role of OGG1 in ASFV infection.We found that ASFV infection induced high levels and dynamic changes in ROS and 8-oxoG and consistently increased the expression of OGG1.Viral yield,transcription level,and protein synthesis were reduced in ASFV-infected primary alveolar macrophages(PAMs)treated by TH5487 or SU0268 inhibiting OGG1.The expression of BER pathway associated proteins of ASFV was also suppressed in OGG1-inhibited PAMs.Furthermore,OGG1 was found to negatively regulate interferonβ(IFN-β)production during ASFV infection and IFN-βcould be activated by OGG1 inhibition with TH5487 and SU0268,which blocked OGG1 binding to 8-oxoG.Additionally,the interaction of OGG1 with viral MGF360-14-L protein could disturb IFN-βproduction to further affect ASFV replication.These results suggest that OGG1 plays the crucial role in successful viral infection and OGG1 inhibitors SU0268 or TH5487 could be used as antiviral agents for ASFV infection. | Jie Fan Xinqian Lv Saixia Yang Shuxian Geng Jifei Yang Yaru Zhao Zhonghui Zhang Zhijie Liu Guiquan Guan Jianxun Luo Qiaoying Zeng Hong Yin Qingli Niu | 2023 | Virologica Sinica2023，38，1： | 1 |
| 11 | Effectof some natural minerals on transformation behaviorof sulfur during pyrolysis of coal and biomass 显示文摘 | Wang Baofeng Zhao Shuguang Huang Yaru | 2014 | J AnalAppl Pyrol2014，105，： | 1 |
| 12 | Tacit Knowledge Mining:The Key Traditional Chinese Medical Inheritance显示文摘Traditional Chinese medicine(TCM)is a treasure of traditional Chinese culture and a gift to the world.TCM tacit knowledge refers to the knowledge and experiences formed in the process of learning and practice of TCM.The objective of this study is to discuss the importance of TCM tacit knowledge in the inheritance and education of TCM.As the essence of the TCM,TCM tacit knowledge has the characteristics of massive,complicated,relativistic,highly individualized,constantly innovative,the dependence of cultural background and the regional environment,as well as difficult to explicate.It exists in every aspect of the TCM theory and the process of dialectical treatment.Besides the traditional master‑apprentice,family‑based,school‑based,and inheritance and education methods,together with the inheritance based on the books,images,and network platforms,in the process of TCM modernization,a variety of modern theoretical models and computing techniques have also been used in the mining of the TCM tacit knowledge.In this study,we introduced the usage of SECI model,complexity adaptive system,latent variable model,and some of the data mining technologies in the TCM tacit knowledge mining.An accurate and efficient inheritance of TCM tacit knowledge is the key to maintain the vitality and innovative development of TCM.Under the reasonable application and combination of the traditional education methods,modern mining methods,and further the artificial intelligence,the explicit and inheritance of TCM tacit knowledge will get tremendous development,and it could extremely improve the efficiency and accuracy of the TCM inheritance and the TCM modernization. | Xu Lan Junnan Zhao Ying Zhang Yao Chen Yaru Yan Yue Liu Fengqin Xu | 2020 | Chinese Medicine and Culture2020，3，1： | 1 |
| 13 | Aerogels from quaternary ammonium-functionalized cellulose nanofibers for rapid removal of Cr(VI) from water显示文摘 | Xu He Long Cheng Yaru Wang Jiangqi Zhao Wei Zhang Canhui Lu | 2014 | Carbohydrate Polymers2014，，： | 1 |
| 14 | Ample dietary fat reduced the risk of primary vesical calculi by inducing macrophages to engulf budding crystals in mice显示文摘Although primary vesical calculi is an ancient disease,the mechanism of calculi formation remains unclear.In this study,we established a novel primary vesical calculi model with D,L-choline tartrate in mice.Compared with commonly used melamine and ethylene glycol models,our model was the only approach that induced vesical calculi without causing kidney injury.Previous studies suggest that proteins in the daily diet are the main contributors to the prevention of vesical calculi,yet the effect of fat is overlooked.To assay the relationship of dietary fat with the formation of primary vesical calculi,D,L-choline tartrate-treated mice were fed a high-fat,low-fat,or normal-fat diet.Genetic changes in the mouse bladder were detected with transcriptome analysis.A high-fat diet remarkably reduced the morbidity of primary vesical calculi.Higher fatty acid levels in serum and urine were observed in the high-fat diet group,and more intact epithelia in bladder were observed in the same group compared with the normal-and low-fat diet groups,suggesting the protective effect of fatty acids on bladder epithelia to maintain its normal histological structure.Transcriptome analysis revealed that the macrophage differentiation-related gene C-X-C motif chemokine ligand 14(Cxcl14)was upregulated in the bladders of high-fat diet-fed mice compared with those of normal-or low-fat diet-fed mice,which was consistent with histological observations.The expression of CXCL14 significantly increased in the bladder in the high-fat diet group.CXCL14 enhanced the recruitment of macrophages to the crystal nucleus and induced the transformation of M2 macrophages,which led to phagocytosis of budding crystals and prevented accumulation of calculi.In human bladder epithelia(HCV-29)cells,high fatty acid supplementation significantly increased the expression of CXCL14.Dietary fat is essential for the maintenance of physiological functions of the bladder and for the prevention of primary vesical calculi,which provides new ideas for the reduction of morbidity of primary vesical calculi. | Huiling Chen Kaiqiang Hu Yaru Liang Yuqi Gao Chenye Zeng Kang Xu Xiaojin Shi Liyuan Li Yuemiao Yin Yi Qiao Ying Qiu Qingfei Liu Zhao Wang | 2022 | Acta Pharmaceutica Sinica B2022，12，2： | 1 |
| 15 | Cr^(3+)pre-intercalated hydrated vanadium oxide as an excellent performance cathode for aqueous zinc-ion batteries显示文摘Rechargeable aqueous zinc-ion batteries(ZIBs)are regarded as the next promising large scale energy storage systems owing to their low cost,high safety and environmental friendliness.Vanadium-based materials are one of the most important cathodes of ZIBs due to their high abundance and multielectron transfer of various oxidations of vanadium.Nevertheless,the strong electrostatic interaction between Zn^(2+)and cathodes,intrinsic poor electronic conductivity and solubility of vanadium-based cathodes in electrolytes bring about inferior electrochemical performance.In this work,we introduce aliovalent Cr^(3+)into the interlayer of hydrated vanadium oxide(Cr-VOH)as pillar to significantly increase the structural stability and electrochemical reversibility.The pre-intercalation of Cr^(3+)also provides an enhanced electronic conductivity and fast Zn^(2+)diffusion dynamics,enabling superior Zn2+storage performance of the Cr-VOH cathode.As a result,the Cr-VOH cathode exhibits a high reversible discharge capacity of~380 mAh g^(−1)at 50 mA g^(−1),excellent rate capacity of 166 mAh g^(−1)at 8 A g^(−1)and prolonged cycling stability over 500 cycles.Furthermore,it displays a high energy density of 273.6 W h kg^(−1)at 0.05 A g^(−1)and the power density of 4960 W kg^(−1)at 8 A g^(−1),contributing to the practical application potential of aqueous ZIBs. | Yaru Zhang Lina Zhao Aibing Chen Jie Sun | 2021 | Fundamental Research2021，1，4： | 1 |
| 16 | A novel thermophilic xylanase from Achaetomium sp. Xz-8 with high catalytic efficiency and application potentials in the brewing and other industries显示文摘 | Liang Zhao Kun Meng Pengjun Shi Yingguo Bai Huiying Luo Huoqing Huang Yaru Wang Peilong Yang Bin Yao | 2013 | Process Biochemistry2013，，12： | 1 |
| 17 | Investigation of Linarinic acid and one of its derivatives against cerebral ischemia in mice显示文摘The study aims to investigate the effects of(-)-Linarinic acid(LA) and one of its derivatives(LAd) on brain injury induced by ischemia. Malonaldehyde(MDA) is determined as an index for lipid peroxidation both in vitro and vivo. Mice were pre-treated with LA and LAd for 3 d.Thereafter, they were induced to have incomplete cerebral ischemia with both bilateral carotid artery occlusion and hypotension(BCAOH). In the first part of the in vivo experiment, mice were divided into four groups: sham(control), ischemia, ischemia + LA(200 mg/kg, i.g.) and ischemia + LAd(200 mg/kg, i.g.). In the second part, the dose-response of LAd was investigated at 100, 200 and 400 mg/kg i.g., respectively. A modified neurological severity score was developed for evaluating behavioral deficits of the mice with ischemia. Brains of the mice were excised in order to determinate MDA after ischemia for 6 h. Survival time, survival rate, neurological injury score and MDA level in brains were observed. Results were: 1) The data in vitro showed that both LA and LAd could inhibit the generation of MDA. IC50 values obtained by Probit analysis were 2.9 mM for LAd and 4.88 mM for LA;2) BCAOH could significantly shorten the survival span, reduce the survival rate and cause neurological deficits,which were associated with high level of lipid hydroperoxide production in cerebral tissues;3) LAd decreased lipid peroxidation and improved the neurological outcome more than LA.It is concluded that LAd offers a better neuroprotection than LA against brain damage caused by cerebral ischemia. | Yihan Wang Chao Zhao Qiujv Wang Huimin Wen Yaru Gu Linlin Fan Chao Ma Maosheng Cheng Yuyang Zhang | 2017 | Asian Journal of Pharmaceutical Sciences2017，12，2： | 1 |
| 18 | Two-in-one shell configuration for bimetal selenides toward fast sodium storage within broadened voltage windows显示文摘The shell structure design has been recognized as a highly efficient strategy to buffer the severe volume expansion and consecutive pulverization of conversion-type anodes.Nevertheless,construction of a functional shell with a stabilized structure that meets the demands of both high electronic conductivity and feasible pathways for Na^(+)ions has been a challenge so far.Herein,we design a two-in-one shell configuration for bimetal selenides to achieve fast sodium storage within broadened voltage windows.The hybridized shell,which benefits from the combination of titanium dioxide quantum dots and amorphous carbon,can not only effectively buffer the strain and maintain structural integrity but also allow facile and reversible transport of electrons and Na^(+)uptake for electrode materials during sodiation/desodiation processes,resulting in increased reaction kinetics and diffusion of sodium ions,conferring many benefits to the functionality of conversion-type electrode materials.As a representative material,Ni-CoSe_(2) with such structural engineering shows a reversible capacity of 515 mAh g^(−1)at 0.1 A g^(−1)and a stable capacity of 416 mAh g^(−1)even at 6.4 A g^(−1);more than 80%of the capacity at 0.1 A g^(−1)could be preserved,so that this strategy holds great promise for designing fast-charging conversion-type anodes in the future. | Zichao Yan Lingfei Zhao Yaru Liang Lei Zhang Hanwen Liu Zhiqiang Zhu Yunxiao Wang Shu-Lei Chou | 2022 | Carbon Energy2022，4，4： | 1 |
| 19 | Research status and prospect of separators for magnesium-sulfur batteries显示文摘Magnesium-sulfur(Mg-S)batteries have attracted wide research attention in recent years,and are considered as one of the major candidates to replace lithium-ion batteries due to the high theoretical energy density,low costs of active materials,and high safety.However,there are still significant challenges that need to be overcome before they can reach the large-scale practical applications.The key issue is the dissolution and shuttle effect of magnesium polysulfides(Mg-PSs),which leads to severe capacity degradation and shortens cycling life,greatly limiting the development of Mg-S batteries.In order to overcome these challenges,great efforts have been made in cathode materials,electrolytes,and separators.Herein,we review the investigations on suppressing the shuttle effect of Mg-PSs via the modification of separators,including schemes such as coating the functional materials that can hold Mg-PSs on the surface of polyolefin-based or glass fiber(GF)separators,forming gel polymer separators via cross-linking polymerization reactions,and developing gel polymer electrolytes coupled with GF separators.Furthermore,an outlook is proposed for the future design on separator exploitation to accelerate the development of Mg-S battery technology. | Shaopeng Chen Yaru Wang Yukun Sun Duo Zhang Shuxin Zhang Yazhen Zhao Jiulin Wang Jun Yang Yanna NuLi | 2023 | Journal of Energy Chemistry2023，，12： | 0 |
| 20 | Heat-inducible SlWRKY3 confers thermotolerance by activating the SlGRXS1 gene cluster in tomato显示文摘High temperature stress is one of the major environmental factors that affect the growth and development of plants. Although WRKY transcription factors play a critical role in stress responses, there are few studies on the regulation of heat stress by WRKY transcription factors,especially in tomato. Here, we identified a group I WRKY transcription factor, SlWRKY3, involved in thermotolerance in tomato. First, SlWRKY3 was induced and upregulated under heat stress. Accordingly, overexpression of SlWRKY3 led to an increase, whereas knock-out of SlWRKY3 resulted in decreased tolerance to heat stress. Overexpression of SlWRKY3 accumulated less reactive oxygen species(ROS), whereas knock-out of SlWRKY3 accumulated more ROS under heat stress. This indicated that SlWRKY3 positively regulates heat stress in tomato. In addition,SlWRKY3 activated the expression of a range of abiotic stress-responsive genes involved in ROS scavenging, such as a SlGRXS1 gene cluster.Further analysis showed that SlWRKY3 can bind to the promoters of the SlGRXS1 gene cluster and activate their expression. Collectively, these results imply that SlWRKY3 is a positive regulator of thermotolerance through direct binding to the promoters of the SlGRXS1 gene cluster and activating their expression and ROS scavenging. | Ying Wang Wenxian Gai Liangdan Yuan Lele Shang Fangman Li Zhao Gong Pingfei Ge Yaru Wang Jinbao Tao Xingyu Zhang Haiqiang Dong Yuyang Zhang | 2024 | Horticultural Plant Journal2024，10，2： | 0 |
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