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| 1 | 动脉粥样硬化血栓形成门诊患者1年内心血管事件的发生率显示文摘背景:目前,有关社区中动脉粥样硬化血栓形成稳定患者心血管(cardiovascular,CV)事件发生率的资料比较少,既往也无国际性队列研究对冠状动脉病(coronary artery disease,CAD)、脑血管病(cerebrovascular disease,CVD)、外周动脉病(peripheral arterial disease,PAD)确诊患者以及此类疾病高危患者不同事件的发生率进行评估。
目的:在患有动脉疾病的门诊患者或存在多个动脉粥样硬化血栓形成危险因素的门诊患者中确定当今世界1年内CV事件的发生率。
设计、地点及参试者:“减少动脉粥样硬化血栓形成维系健康(Reduction of Artherotllrombosis for Continued Health,REACH)”注册研究是一项国际前瞻性队列研究。研究人员于2003—2004年从44个国家、5587名医生入选68236例已确诊的动脉粥样硬化性血管病患者(CAD、PAD、CVD;n=55814)以及至少存在3个动脉粥样硬化血栓形成危险因素的患者(n=12422)。
主要观测指标:CV死亡、心肌梗死(myocardial infarction,MI)及卒中的发生率。结果:截至2006年7月,共有95.22%的患者(n=64977)提供了1年内的结局。心血管死亡、MI及卒中的总体发生率为4.24%;动脉粥样硬化性血管病患者为4.69%,仅存在多个危险因素的患者为2.15%。CAD、CVD及PAD患者CV死亡、MI及卒中的总体发生率分别为4.52%、6.47%和5.35%。CAD、CVD及PAD患者发生终点事件(即CV死亡、MI、卒中)以及因动脉粥样硬化血栓形成事件入院的几率分别为15.20%、14.53%和21.14%。上述事件发生率随症状性动脉疾病病变部位数量的增加而增加,仅存在危险因素的患者为5.31%,有1处症状性动脉疾病的患者为12.58%,有2处症状性动脉疾病的患者为21.14%,有3处症状性动脉疾病的患者为26.27%(趋势P〈0.001)。
结论:在这项当代大型国际研究中,患有动脉粥样硬化性血管病的门诊患者以及有动脉粥样硬化血栓形成危险的门诊患者CV事件的年发生率相对较高。存在多部位病变者CV事件的1年发生率升高。 | Gabriel Steg Deepak L. Bhatt Peter W. F. Wilson Ralph D' Agostino E. Magnus Ohman Joachim Roether Chiau-Suong Liau Alan T. Hirsch Jean-Louis Mas Yasuo Ikeda Michael J. Pencina Shinya Goto 徐成斌(译) 李呈亿(校) | 2007 | 美国医学会杂志(中文版)2007，26，4： | 20 |
| 2 | 世界各地动脉粥样硬化血栓形成门诊患者心血管危险因素的流行及诊治情况显示文摘背景:动脉粥样硬化血栓形成是导致心血管疾病和死亡的主要原因。至今,尚无国际数据库阐述动脉粥样硬化血栓形成患者动脉硬化危险因素的特征和治疗强度。
目的:确定动脉粥样硬化危险因素的发生及治疗在世界许多国家是否具有可比性。设计、地点及参试者:“降低动脉粥样硬化血栓形成保持健康研究”(Reduction of Atherothrombosis for Continued Health,REACH)搜集了动脉粥样硬化危险因素及治疗情况的数据。从2003年到2004年,44个国家、5473位内科从业医师总共发现67888例年龄≥45岁的动脉病患者(冠心病[coronaryartery disease,CAD],n=40258;脑血管病,n=18843;周围动脉病,n=8273)或≥3个动脉粥样硬化血栓形成危险因素(n=12389)。主要观测指标:动脉粥样硬化危险因素的基线发生率、药物应用情况及危险因素控制程度。结果:全世界动脉粥样硬化血栓形成患者具有相似的危险因素,即高血压(81.8%)、高胆固醇血症(72.4%)以及糖尿病(44.3%)的比例高。超重(39.8%)、肥胖(26.6%)以及病态肥胖(3.6%)的发生率在大部分地区相似,但是以北美最高(超重:37.1%,肥胖:36.5%,病态肥胖:5.8%;与其他地区比较P〈0.001)。患者采用他汀(总共69.4%;范围:从脑血管病的56.4%到CAD的76.2%)、抗血小板治疗(总共78.6%;范围:从≥3个危险因素的53.9%到CAD的85.6%)及其他循证(降低危险)普遍不足。确诊有血管病的患者在吸烟者为数可观(14.4%)。高血压病治疗不足(基线50.0%血压升高)、高血糖诊断不足(4.9%)以及空腹血糖受损(其中36.5%不知已有糖尿病)均很常见。在有症状的动脉粥样硬化血栓形成患者中,15.9%是有症状的多血管疾病患者。
结论:这项当代大型国际数据库研究显示,在世界许多地区典型心血管危险因素的发生是一致且常见的,但是大多治疗不足、控制不得力。 | Deepak L. Bhatt, MD P. Gabriel Steg, MD E. Magnus Ohman, MD Alan T. Hirsch, MD Yasuo Ikeda, MD Jean-Louis Mas, MD Shinya Goto, MD Chlau-Suong Liau, MD, PhD Alain J. Richard, MD, PhD Joachim Roether, MD Peter W. F. Wilson, MD 徐成斌(译) | 2007 | 美国医学会杂志(中文版)2007，26，1： | 5 |
| 3 | Ectopic gastrointestinal variceal bleeding with portal hypertension显示文摘Massive gastrointestinal bleeding from gastrointestinal varices is one of the most serious complications in patients with portal hypertension. However, if no bleeding point can be detected by endoscopy in the predilection sites of gastrointestinal varices, such as the esophagus and stomach, ectopic gastrointestinal variceal bleeding should be considered as a differential diagnosis. Herein, we report a case of ectopic ileal variceal bleeding in a 57-year-old woman, which was successfully diagnosed by multi-detector row CT(MDCT) and angiography and treated by segmental ileum resection. To date, there have been no consensus for the treatment of ectopic ileal variceal bleeding. This review was designed to clarify the clinical characteristics of patients with ectopic ileal variceal and discuss possible treatment strategies. From the PubMed database and our own database, we reviewed 21 consecutive cases of ileal variceal bleeding diagnosed from 1982 to 2017. MDCT and angiography is useful for the rapid examination and surgical resection of an affected lesion and is a safe and effective treatment strategy to avoid further bleeding. | Keita Minowa Shuhei Komatsu Kenichiro Takashina Sachie Tanaka Tatsuya Kumano Kenichiro Imura Katsumi Shimomura Jun Ikeda Fumihiro Taniguchi Yasuo Ueshima Tecchuu Lee Eito Ikeda Eigo Otsuji Yasuhiro Shioaki | 2017 | World Journal of Gastrointestinal Surgery2017，9，12： | 4 |
| 4 | A comparison of intraoperative celiac plexus block with pharmacological therapy as a treatment for pain of unresectable pancreatic cancer显示文摘 | Masaki Okuyama Takashi Shibata Tetsushi Morita Masashi Kitada Yasuo Tukahara Yukio Fukushima Kimimasa Ikeda Junya Fuzita Takashi Shimano | 2002 | Journal of Hepato - Biliary - Pancreatic Surgery2002，，3： | 2 |
| 5 | Specificity of chitosanase from Bacillus pumilus显示文摘 | Tamo Fukamizo Takeshi Ohkawa Yasuo Ikeda | 1994 | Biochimica et Biophysica Acta1994，1205，： | 1 |
| 6 | Involvement of NF-κB activation in the cisplatin resistance of humanepidermoid carcinoma KCP-4 cells显示文摘 | Shigeru Oiso Ryuji Ikeda Kazuo Nakamura Yasuo Takeda Shin-Ichi Akiyama Hiroko Kariyazono | 2012 | Oncology Reports2012，，1： | 1 |
| 7 | Risk factor profiles, drug usage, and prevalence of aspirin-associated gastroduodenal injuries among high-risk cardiovascular Japanese patients: the results from the MAGIC study显示文摘 | Naomi Uemura Kentaro Sugano Hideyuki Hiraishi Kazuyuki Shimada Shinya Goto Shinichiro Uchiyama Yasushi Okada Hideki Origasa Yasuo Ikeda | 2014 | Journal of Gastroenterology2014，，： | 1 |
| 8 | Breast cancer risk associated with polymorphism in CYP19 in Japanese women 显示文摘 | Yasuo Miyoshi Kyoko lwao Noriko Ikeda | 2000 | Int J Cancer2000，89，： | 1 |
| 9 | A novel therapeutic approach for hematological malignancies based on cellular differentiation and apoptosis显示文摘 | Masahiro Kizaki Tomonori Nakazato Keisuke Ito Chiharu Kawamura Yoshitaka Miyakawa Yasuo Ikeda | 2002 | International Journal of Hematology2002，，1： | 1 |
| 10 | Founction of fibrinogen γ-chain dodecapeptide-conjugated latex beads under flow显示文摘 | Shinji Takeoka Yosuke Okamura Yasuo Ikeda | 2003 | Biomedical and Biophysical Resarch Commucations2003，312，： | 1 |
| 11 | Abscess in the inguinal hernial sac after peritonitis surgery: A case report显示文摘In this paper, we report an extremely rare case of an abscess that developed in the inguinal hernial sac after surgery for peritonitis. A 60-year-old man underwent laparoscopic low anterior resection for rectal cancer. One day after this operation, peritoneal drainage and ileostomy were performed for rectal anastomotic leakage. Five days after the second operation, computed tomography revealed an abscess in the left inguinal hernial sac. Subsequently, hernioplasty and resection of the inflamed sac were performed. | Satoshi Ikeda Haruka Takeda Masanori Yoshimitsu Takao Hinoi Makoto Yoshida Daisuke Sumitani Yuji Takakura Yasuo Kawaguchi Manabu Shimomura Masakazu Tokunaga Katsufumi Kawahori Hideki Ohdan Masazumi Okajima | 2009 | World Journal of Gastroenterology2009，15，8： | 1 |
| 12 | Molecular basis for the expression of major vault protein induced byhyperosmotic stress in SW620 human colon cancer cells显示文摘 | Yusuke Tajitsu Ryuji Ikeda Yukihiko Nishizawa Hirofumi Mataki Xiao-Fang Che Tomoyuki Sumizawa Mina Nitta Tatsuya Yamaguchi Masatatsu Yamamoto Sho Tabata Shin-Ichi Akiyama Katsushi Yamada Tatsuhiko Furukawa Yasuo Takeda | 2013 | International Journal of Molecular Medicine2013，，3： | 1 |
| 13 | Increase of Bone Marrow–Derived Secretory Lineage Epithelial Cells During Regeneration in the Human Intestine显示文摘 | Tomoko Matsumoto Ryuichi Okamoto Tomoharu Yajima Takehiko Mori Shinichiro Okamoto Yasuo Ikeda Makio Mukai Motomi Yamazaki Shigeru Oshima Kiichiro Tsuchiya Tetsuya Nakamura Takanori Kanai Hideyuki Okano Johji Inazawa Toshifumi Hibi Mamoru Watanabe | 2005 | Gastroenterology2005，，7： | 1 |
| 14 | Infected duodenal duplication with unusual clinical and radiological manifestations: a case report显示文摘 | Kiyohiro Oshima Norio Suzuki Hitoshi Ikeda Atsushi Takahashi Minoru Kuroiwa Shigeru Ohki Shin-itsu Hatakeyama Yoshiaki Tsuchida Yasuo Morishita | 1998 | Pediatric Radiology1998，，7： | 1 |
| 15 | Preservation of peritoneal fibrinolysis owing to decreased transcription of plasminogen activator inhibitor-1 in peritoneal mesothelial cells suppresses postoperative adhesion formation in laparoscopic surgery显示文摘 | Manabu Shimomura Takao Hinoi Satoshi Ikeda Tomohiro Adachi Yasuo Kawaguchi Masakazu Tokunaga Tatsunari Sasada Hiroyuki Egi Kazuaki Tanabe Masazumi Okajima Hideki Ohdan | 2012 | Surgery2012，，： | 1 |
| 16 | Prevalence of constipation in continuous ambulatory peritoneal dialysis patients and comparison with hemodialysis patients显示文摘 | Gen Yasuda Kazuhiko Shibata Toshikazu Takizawa Yumiko Ikeda Yasuo Tokita Satoshi Umemura Osamu Tochikubo | 2002 | American Journal of Kidney Diseases2002，，6： | 1 |
| 17 | Preoperative Iron Supplementation and Intraoperative Transfusion During Colorectal Cancer Surgery显示文摘 | Masaki Okuyama Kimimasa Ikeda Takashi Shibata Yasuo Tsukahara Masashi Kitada Takashi Shimano | 2005 | Surgery Today2005，，1： | 1 |
| 18 | Autoreactive T cells to platelet GP Ⅱ b/Ⅲ a in immune thromboeytopenic purpura显示文摘 | Masataka Kuwana Junichi kaburaki Yasuo Ikeda | 1998 | J Clin Invest1998，102，7： | 1 |
| 19 | Specific Inhibiting Characteristics of Tetramethylpyrazine, One of the Active Ingredients of the Chinese Herbal Medicine ‘Chuanxiong,’ on Platelet Thrombus Formation Under High Shear Rates显示文摘 | Min Li Shunnosuke Handa Yasuo Ikeda Shinya Goto | 2001 | Thrombosis Research2001，，1： | 1 |
| 20 | Clinicopathologic study of small hepatocellular carcinoma with microscopicsatellite nodules to determine the extent of tumor ablation by local therapy显示文摘 | Kozo Ikeda Toshihito Seki Hideto Umehara Ryosuke Inokuchi Toru Tamai Noriko Sakaida Yoshiko Uemura Yasuo Kamiyama Kazuichi Okazaki | 2007 | International Journal of Oncology2007，，3： | 1 |
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