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| 1 | Macleaya cordata extract alleviated oxidative stress and altered innate immune response in mice challenged with enterotoxigenic Escherichia coli显示文摘This study examines the effects of dietary Macleaya cordata extract(MCE) on bacterial burden and resistance to enterotoxigenic Escherichia coli(ETEC) in ICR mice. ICR mice were randomly distributed into one of the following groups:(i) basal diet;(ii)basal diet with 200 mg kg–1 MCE;(iii) basal diet challenged with ETEC;and(iv) basal diet with 200 mg kg–1 MCE and challenged with ETEC. Following a 7-day period of pre-treatment, CTRL-ETEC and MCE-ETEC mice were subjected to oral infection using 5×108 E. coli SEC 470. The results showed dietary 200 mg kg–1 MCE markedly reduced intestinal ETEC burden(P<0.05) and the disease-associated mortality was significantly alleviated in the MCE treated group(P<0.05). In addition,dietary MCE markedly alleviated ETEC-induced oxidative stress, evidenced by the lowered methane dicarboxylic aldehyde(MDA) abundance and enhanced activities of catalase and glutathione peroxidase(P<0.05). Furthermore, MCE mice exhibited higher immune activity, which might have further mediated ETEC infection. These results indicate MCE plays a preventative role with respect to ETEC infection. Future research should aim to develop MCE as a therapeutic approach to the promotion of intestinal health and a safeguard against ETEC infection. | Guiping Guan Sujuan Ding Yulong Yin Veeramuthu Duraipandiyan Naif Abdullah Al-Dhabi Gang Liu | 2019 | Science China(Life Sciences)2019，62，8： | 12 |
| 2 | Heat transfer performance for DCLL blanket with no-wetting insulator walls显示文摘Magnetohydrodynamic (MHD) effect and heat transfer are two key issues for design of dual coolant lead lithium (DCLL) blanket. Flow channel insert (FCI) has been applied to decouple the liquid metal from the walls to efficiently decline MHD pressure drops and reduce heat losses from the liquid metal for increasing bulk exit temperatures of the blanket. However, there are still big pressure drops and a higher velocity jet located at the gap flow. Moreover, the FCI made from silicon carbide (SiC) constitutes a complex blanket structures which potentially causes special flow phenomena. In the present work, the characteristics of fluid flow and heat transfer in the DCLL blanket channel are investigated for the first wall (FW) sprayed a layer of no-wetting nano coating (NWNC) on its inner surface. The results show that the pressure drop with NWNC wall is oneorder magnitude lower than that with FCI in the general DCLL blanket. The Nusselt number on the NWNC wall is about half of that on the general wall. On this basis, a heat transfer criterion equation of DCLL channel is achieved for the NWNC wall without FCI. The results are compared with that criterion equation of general wall conditions, which indicates the criterion equation can well predict the convection heat transfer of DCLL channel. | Hulin Huang Shimou Yin Guiping Zhu | 2019 | Theoretical & Applied Mechanics Letters2019，9，3： | 1 |
| 3 | Fibroblast growth factor (FGF)-21 signals through both FGF receptor-1 and 2显示文摘Fibroblast growth factor (FGF)-21 is a member of the FGF superfamily based on sequence homology. However, unlike most members of this family it does not show any mitogenic activity in all cell types tested. The objective of this study is to identify and characterize receptors for this molecule. Sequencing of the cDNA clones from 3T3-L1 adipocytes indicates that the only isoforms for FGFR-1 and 2 expressed in 3T3-L1 cells are 1IIIc and 2IIIc, respectively, suggesting that FGF-21 regulates glucose metabolism in 3T3-L1 adipocytes through FGFR-1IIIc and FGFR-2IIIc. | REN GuiPing, YIN JieChao, WANG WenFei, LI Lu & LI DeShan College of Life Science, Northeast Agricultural University, Harbin 150030, China | 2010 | Science China(Life Sciences)2010，53，8： | 1 |
| 4 | Expressions of farnesoid X receptor and myeloid cell leukemia sequence 1 protein are associated with poor prognosis in patients with gallbladder cancer显示文摘 | Wang Wei Yin Xiaobin Li Guiping Yi Jing Wang Jian | 2014 | Chinese Medical Journal2014，，14： | 1 |
| 5 | Expression analysis and antiviral properties of the Beijing - Yon and White Leghorn myxovirus resistance gene with different ami- no acids at position 631 显示文摘 | Chunguang Yin Chuansheng Zhang Aimin Zhang Hongwei Qin Xiaoqiang Wang GuiPing Zhao Lixin Du | 2010 | Poultry Science2010，89，： | 1 |
| 6 | Assessing China's ecolog ical restoration programs: Whafs been done and what remains to be done显示文摘 | Yin Runsheng Yin Guiping Li Lanying | 2010 | Environmental Management2010，45，3： | 1 |
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