|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Service-aware 6G:An intelligent and open network based on the convergence of communication,computing and caching显示文摘With the proliferation of the Internet of Things(IoT),various services are emerging with totally different features and requirements,which cannot be supported by the current fifth generation of mobile cellular networks(5G).The future sixth generation of mobile cellular networks(6G)is expected to have the capability to support new and unknown services with changing requirements.Hence,in addition to enhancing its capability by 10–100 times compared with 5G,6G should also be intelligent and open to adapt to the ever-changing services in the IoT,which requires a convergence of Communication,Computing and Caching(3C).Based on the analysis of the requirements of new services for 6G,this paper identifies key enabling technologies for an intelligent and open 6G network,all featured with 3C convergence.These technologies cover fundamental and emerging topics,including 3C-based spectrum management,radio channel construction,delay-aware transmission,wireless distributed computing,and network self-evolution.From the detailed analysis of these 3C-based technologies presented in this paper,we can see that although they are promising to enable an intelligent and open 6G,more efforts are needed to realize the expected 6G network. | Yiqing Zhou Ling Liu Lu Wang Ning Hui Xinyu Cui Jie Wu Yan Peng Yanli Qi Chengwen Xing | 2020 | Digital Communications and Networks2020，6，3： | 57 |
| 2 | Association of KIR Genotypes and Haplotypes with Susceptibility to Chronic Hepatitis B Virus Infection in Chinese Han Population显示文摘Killer immunoglobulin-like receptor (KIR) genes can regulate the activation of NK and T cells upon interaction with HLA class I molecules. Hepatitis B virus (HBV) infection has been regarded as a multi-factorial disorder disease. Previous studies revealed that KIRs were involved in HCV and HIV infection or clearance. The aim of this study was to explore the possibility of the inheritance of KIR genotypes and haplotypes as a candidate for susceptibility to persistent HBV infection or HBV clearance. The sequence specific primer polymerase chain reaction (SSP-PCR) was employed to identify the KIR genes and pseudogenes in 150 chronic hepatitis B (CHB) patients, 251 spontaneously recovered (SR) controls, and 412 healthy controls. The frequencies of genotype G, M, FZ1 increased in CHB patients compared with healthy control subjects. The frequency of genotype AH was higher in SR controls than that in both CHB patients and healthy controls. The carriage frequencies of genotype G and AH were higher; while, the frequencies of AF and AJ were lower in SR controls than those in healthy control subjects. The frequency of A haplotype was lower, whereas, the frequency of B haplotype was higher in CHB patients and SR controls than those in healthy controls. In healthy controls, haplotype 4 was found lower compared with that in CHB patients and SR controls and the frequency of haplotype 5 was higher in SR controls than that in other two groups. Based on these findings, it seems that the genotypes M and FZ1 are HBV susceptive genotypes; AH, on the other hand, may be protective genotypes that facilitate the clearance of HBV. It appears that the haplotype 4 is HBV susceptive haplotype, whereas, haplotype 5 may be the protective haplotype that facilitates the clearance of HBV. | Zhiming Lu Bingchang Zhang Shijun Chen Zhongtao Gai Zhaolei Feng Xiangdong Liu Yiqing Liu Xin Wen Li Li Yulian Jiao Chunyan Ma Song Shao Xiangfa Cui Guojian Chen Jianfeng Li Yneran Zhao | 2008 | Cellular & Molecular Immunology2008，5，6： | 13 |
| 3 | Thrombolysis with alteplase 3-4.5 hours after acute ischaemic stroke:the first multicentre,phase III trial in China显示文摘background and purpose Data on the efficacy and safety of alteplase for acute ischaemic stroke(AIS)administered 3-4.5 hours after the onset of stroke symptoms in Chinese patients is limited.We sought to determine whether AIS patients would benefit from thrombolysis with alteplase between 3 and 4.5 hours after the onset of stroke symptoms in a prospective,multicentre,single-arm trial in China.Materials and methods Eligible AIS patients were given 0.9 mg/kg alteplase intravenously.The primary efficacy endpoint was a favourable outcome at 3 months,defined as a score of 0 or 1 on the modified Rankin Scale.Thresholds for the primary efficacy endpoint were determined to be 40%based on the literature review.The primary safety endpoint was symptomatic intracranial haemorrhage(sICH)according to the European Cooperative Acute Stroke Study III(ECASS III)trial definition.Post hoc analysis between this study and the ECASS III trial were compared using the propensity score matching(PSM)method.results A total of 120 eligible AIS patients from 11 sites in China received thrombolysis therapy in this study.The median time from onset of symptoms to needle was 3 hours 54 min.The percentage of patients with a favourable outcome was 63.3%(95%CI 54.4 to 71.4),significantly higher than the predefined threshold(p<0.0001).Three patients(2.5%,95%CI 0.5 to 7.1)had sICH,including two fatal sICH.Six patients died within 3 months after treatment.The post hoc PSM analysis showed a numerically higher rate of the primary efficacy endpoint in this study(63.3%)than the matched placebo arm(56.7%)in the ECASS III trial.Conclusions Intravenous alteplase with a standard dose administered between 3 and 4.5 hours after onset of symptoms is effective and safe for Chinese AIS patients. | Huaguang Zheng Yi Yang Huisheng Chen Chuanling Li Yangkun Chen Fu-Dong Shi Li Yang Xiaoping Cui Zuneng Lu Yanling Liang Songbiao Cui Anding Xu Yiqing Wu Yaqing Sun Yongjun Wang | 2020 | Stroke & Vascular Neurology2020，5，3： | 4 |
| 4 | Mutations in TP53, ZNF750, and RB1 typify ocular sebaceous carcinoma显示文摘Sebaceous carcinoma (SC) of the eyelid is a rare but aggressive malignancy, accounting for 3%—5% of eyelid malignancies in the United States, and up to 35% in Asian populations (Deprez and Uffer, 2009;Xu et al., 2018;Yu et al., 2018). It is frequently mistaken for benign conditions or less aggressive malignancies such as basal cell carcinoma (Muqit et al., 2013), and the effects of delay in diagnosis can be devastating to patients. Aggressive surgical resection is the primary treatment of these tumors and often invoIves orbital exenteration with significant morbidity to patients, and these tumors frequently recur, with local recurrence rate as high as 18%. Importantly, this disease has a high metastatic potential, and there are very limited data guiding systemic treatment options;ultimately 6%—18% of patients diagnosed with SC of the eyelid succumb to metastatic disease (Zurcher et al., 1998;Shields et al., 2004). | Yongyang Bao J. Eva Selfridge Janet Wang Yiqing Zhao Junqi Cui Kishore Guda Zhenghe Wang Yanbo Zhu | 2019 | Journal of Genetics and Genomics2019，46，6： | 4 |
| 5 | PulseNet China,a model for future laboratory-based bacterial infectious disease surveillance in China显示文摘Surveillance is critical for the prevention and control of infectious disease.China’s real-time web-based infectious disease reporting system is a distinguished achievement.However,many aspects of the current China Infectious Disease Surveillance System do not yet meet the demand for timely outbreak detection and identification of emerging infectious disease.PulseNet,the national molecular typing network for foodborne disease surveillance was first established by the Centers for Disease Control and Prevention of the United States in 1995 and has proven valuable in the early detection of outbreaks and tracing the pathogen source.Since 2001,the China CDC laboratory for bacterial pathogen analysis has been a member of the PulseNet International family;and has been adapting the idea and methodology of PulseNet to develop a model for a future national laboratory-based surveillance system for all bacterial infectious disease.We summarized the development progress for the PulseNet China system and discussed it as a model for the future of China’s national laboratory-based surveillance system. | Wei Li Shan Lu Zhigang Cui Jinghua Cui Haijian Zhou Yiqing Wang Zhujun Shao Changyun Ye Biao Kan Jianguo Xu | 2012 | Frontiers of Medicine2012，6，4： | 4 |
| 6 | Up-regulation of carcinoembryonic antigen-related cell adhesion molecule 1 in gastrointestinal cancer and its clinical relevance显示文摘 | Muqing Zhou Zhiming Jin Yiwen Liu Yiqing He Yan Du Cuixia Yang Yingzhi Wang Jiajie Hu Lian Cui Feng Gao Manlin Cao | 2017 | Acta Biochimica et Biophysica Sinica2017，49，8： | 2 |
| 7 | Bulk-quantity synthesis and self-catalytic VLS growth of SnO2 nanowires by lower-temperature evaporation显示文摘 | Chen Yiqing Cui Xuefeng Zhang Kun | 2003 | Chemical Physics Letters2003，369，： | 1 |
| 8 | Effects of root and litter exclusion on soil CO 2 efflux and microbial biomass in wet tropical forests显示文摘 | Yiqing Li Ming Xu Osbert J. Sun Wangcheng Cui | 2004 | Soil Biology and Biochemistry2004，，： | 1 |
| 9 | Bulk-quantity synthesis and self-catalytic VLS growth of SnO2 nanowires by lower-temperature evaporation显示文摘 | CHEN Yiqing CUI Xuefeng ZHANG Knn | 2003 | Chemical Physics Letters2003，，12： | 1 |
| 10 | Localization of indoleamine 2,3-dioxygenase in human esophageal squamous cell carcinomas显示文摘 | Jinzhong Liu Gaofeng Lu Fuai Tang Yiqing Liu Guanglin Cui | 2009 | Virchows Archiv2009，，： | 1 |
| 11 | Bulk-quantity synthesis and self-catalytic VLS growth of SnO2 nanowires by lower-temperature evaporation显示文摘 | Chen Yiqing Cui Xuefeng Zhang Kun | 2003 | Chemical Physics Letters2003，，12： | 1 |
| 12 | 显示文摘 | Chen Yiqing Cui Xuefeng Zhang Kun | 2003 | Chem Phys Lett2003，369，： | 1 |
| 13 | GPR54 deficiency reduces the Treg population and aggravates experimental autoimmune encephalomyelitis in mice显示文摘GPR54 is highly expressed in the central nervous system and plays a crucial role in pubertal development. However, GRP54 is also expressed in the immune system, implying possible immunoregulatory functions. Here we investigated the role of GPR54 in T cell and immune tolerance. GPR54 deficiency led to an enlarged thymus, an increased number of thymocytes, and altered thymic micro-architecture starting around puberty, indicating GPR54 function in T-cell development through its regulatory effect on the gonadal system. However, flow cytometry revealed a significant reduction in the peripheral regulatory T cell population and a moderate decrease in CD4 single-positive thymocytes in prepubertal Gpr54^(-/-) mice. These phenotypes were confirmed in chimeric mice with GPR54 deficient bone marrow-derived cells. In addition, we found elevated T cell activation in peripheral and thymic T cells in Gpr54^(-/-) mice. When intact mice were immunized with myelin oligodendrocyte glycoprotein, a more severe experimental autoimmune encephalomyelitis(EAE) developed in the Gpr54^(-/-) mice. Interestingly, aggravated EAE disease was also manifested in castrated and bone marrow chimeric Gpr54^(-/-) mice compared to the respective wild-type control,suggesting a defect in self-tolerance resulting from GPR54 deletion through a mechanism that bypassed sex hormones. These findings demonstrate a novel role for GPR54 in regulating self-tolerant immunity in a sex hormone independent manner. | Roumei Xing Fang Liu Yiqing Yang Xueqin Cui Tongtong Wang Ling Xie Yongliang Zhao Lei Fang Tingfang Yi Biao Zheng Mingyao Liu Huaqing Chen | 2018 | Science China(Life Sciences)2018，61，6： | 1 |
| 14 | Nutritional status in chronically hospitalized stroke patients complicated with pulmonary infection显示文摘Complicated pulmonary infection following stroke has traditionally been considered an aspirated infection by many physicians,and little attention has been paid to concomitant protein-energy malnutrition.In the present study,we hypothesized that protein-energy malnutrition may be present in hospitalized chronic stroke patients complicated with pulmonary infection.The results revealed that body protein and fat stores were significantly depleted in stroke patients with pulmonary infection.Protein-energy malnutrition was present in 12 of 27 patients with pulmonary infection.In comparison,only eight of 42 stroke patients without pulmonary infection exhibited protein-energy malnutrition.A significantly higher prevalence of protein-energy malnutrition was found in the pulmonary infection group,suggesting that protein-energy malnutrition is more likely to be present in hospitalized chronic stroke patients with pulmonary infection. | Yue Chen Lufang Chen Yiqing Tao Maomao Han Chunlan Cui Shichao Liu | 2011 | Neural Regeneration Research2011，6，13： | 0 |
| 15 | Analysis on the Observation Data of Three Profiles across the Qilian Mountain-Haiyuan Fault Zone显示文摘由分析 GPS,铺平并且从 Minle, Huazangsi 和 Shagouhe 的严肃观察数据在 2005 期间介绍 Qilian Mountain-Haiyuan 差错到对面 - 2009,这些数据的变化和在不同时间的主要差错的活动特征被获得。Changma-Erbo, Maomaoshan, Zhunglanghe 和 Haiyuan 指责的结果表演在最近的年里是活跃的。在垂直排水量和活动严肃数据之间的关系被分析,并且结果表明严肃变化主要由于集体转移。水平运动速度的方向几乎沿着差错的 GPS 观察表演的结果在 2006 罢工 - 2007 当水平速度在 2007 从差错方向背离了时 - 2008,由增加的东方排水量描绘了。在连续观察的 N 和 E 坐标值的时间系列上的线性趋势的移动之上的进一步的分析在三侧面附近中国的外壳的运动观察网络驻扎表明 Wenchuan 地震在 2007 在观察上有效果 - 2008。在 2008 比较重力的变化 - 2009 与 Bouguer 严肃异例背景,我们发现 Minle 侧面附近的区域在调整和恢复的阶段,当异例完全没在 Huazangsi 和 Shagouhe 侧面附近被恢复时。 | Hu Yaxuan Wang Xiong Cui Duxin Zhu Yiqing | 2011 | Earthquake Research in China2011，25，4： | 0 |
| 16 | Post-stroke seizures in consecutive elderly stroke patients显示文摘This prospective study sought to investigate the clinical,radiological and electroencephalographic(EEG) characteristics of seizures in elderly stroke patients,and their outcomes.Over a 2-year study period,158 consecutive elderly patients with stroke were examined and followed up.Of these patients,32(20%) developed seizures,primarily related to stroke,within a follow up period between 5 months and 2 years.Of these 32 cases,20 experienced infarctions,and 12 experienced hemorrhages.Involvement of cortical regions was detected in most of the patients exhibiting seizures.In these patients,44% of the lesions involved cortical areas exclusively or in addition to subcortical areas observed on computed tomography(CT) images.Twenty-five patients(78%) developed early seizures(within 2 weeks after stroke),and half exhibited immediate post-stroke seizures.None of the patients exhibiting early onset seizures developed recurrent seizures or epilepsy,while 57% of late onset seizures(four cases) developed epilepsy.No specific EEG patterns were apparent in those who later developed epilepsy.Overall,early onset seizures after stroke were found to be relatively common,and did not affect outcome.Late onset seizures were less common,but were associated with chronic epilepsy. | Yue Chen Lufang Chen Yiqing Tao Maomao Han Chunlan Cui Shichao Liu | 2011 | Neural Regeneration Research2011，6，9： | 0 |
| 17 | Who are on the road? A study on vehicle usage characteristics based on one-week vehicle trajectory data显示文摘Understanding the characteristics of passenger vehicle use is the prerequisite for effective urban management.However,it has been challenging in the existing literature due to the lack of continuously observed data on passenger vehicle use.Thanks to the advances in data collection and processing techniques,multi-day vehicle trajectory data generated from volunteered passenger cars provide new opportunities for examining in depth how people travel in regular patterns.In this paper,based on a week’s operation data of 6600 passenger cars in Shanghai,we develop a systematic approach for identifying trips and travel purposes,and classify vehicles into four categories using a Gaussian-Mixed-Model.A new method is proposed to identify vehicle travel regularities and we use the Z Test to explore differences in travel time and route choices between four types of vehicles.Wefind that commercially used vehicles present high travel intensity in temporal and spatial aspects and the use intensity in elevated roads is higher for household-used commuting vehicles than semi-commercially used vehicles.The methodologies and conclusions of this paper may provide not only theoretical support for future urban traffic prediction,but also guidance for employing customized active traffic demand management measures to alleviate traffic congestion. | Jihao Deng Yiqing Cui Xiaohong Chen Chris Bachmann Quan Yuan | 2023 | International Journal of Digital Earth2023，16，1： | 0 |
| 18 | Early rehabilitation and neuroprotective drug therapy outcomes in elderly patients with acute stroke显示文摘Sixty elderly patients, who suffered from acute stroke and were admitted within a 1-year period to the Department of Geriatrics in the First Affiliated Hospital of School of Medicine, Zhejiang University, China, underwent early rehabilitation in combination with neuroprotective drug therapy. Limb movement, cognitive functions and daily life self-care ability in elderly patients upon admission and discharge were assessed using the Hunt-Hess scale, functional independence measures and mini-mental state examination. The mean duration of hospital stay among the 60 patients was 35 days. Upon discharge, 42 (75%) of the patients exhibited cognitive impairment to varying degrees, and 25 (45%) of the 56 stroke patients who underwent rehabilitation evaluation attained independence in daily living activities, 11 (20%) required intermittent supervision, and 20 (36%) required 24-hour constant supervision during performance of these activities. Results demonstrated that early rehabilitation treatment in combination with neuroprotective therapy for acute stroke was effective. | Yue Chen Lufang Chen Yiqing Tao Feixue Zhou Chunlan Cui Shichao Liu | 2011 | Neural Regeneration Research2011，6，11： | 0 |
| 19 | Exploring the psychological impact of the 2022 SARS-CoV-2 Omicron variant outbreak in China显示文摘To the editor:The impact of the coronavirus disease 2019(COVID-19)pandemic in 2020 on mental health was substantialin Chinai2and various other countries.34 Beyond the direct consequences of COVID-19,the pandemic created an environment in which many determinants of mental health were affected.Issues associated with the pandemic,such as loss of livelihood,limited access to medical services,reduced social interactions,and economic downturn,could potentially have adverse effects on the population's mental well-being.5 In November 2021,the World Health Organization(WHO)designated the new variant of the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),variant B.1.1.529,as a variant of concern and named it Omicron;its rapid mutation and spread raised a new global health concern. | Gangbin Han Guirong Cheng Feifei Hu Chunli Li Dan Liu Juan Zhou Jing Liu Linya Huang Xiaochang Liu Qianqian Nie Dan Song Deyang Zeng Lang Xu Jinquan Li Yushan Chen Zhen Wei Qiong Wu Xiaoming He Qingming Wu Wei Tan Yufei Mei Xingxing Chen Yangming Ou Jingjing ZhangYafu Yu Mengliu Yang Pengfei Lian Fukai Zhou Renjia Fan Hong Wan Chenlu Hu Yidi Fu Shiyue Li Junyi Wang Cheng Cai Mengdie Pei Yuyang Cui Wanying Cai Yiqing Li Shiyao Pan Chang Chen Yan He Zhaoxia Wu Liu Hu Liang Tao Hongyan Xiao Xinyan Xie Yan Zeng | 2023 | General Psychiatry2023，36，6： | 0 |
| 20 | Research Progress in Surface and Marine Gravimetry显示文摘Gravity field is the most basic physical field generated by the material properties of the Earth system.It reflects the spatial distribution,movement and change of materials determined by the interaction and dynamic process inside the Earth.Over the years,a variety of technical means have been used to detect the Earth’s gravity field and supported numerous studies on the global change,resource detection,geological structure movement,water resources change and other related fields of research.Here is part of the progress in surface and marine gravimetry obtained by Chinese geodesy scientists from 2019 to 2023 from the following aspects,including:①Continuous gravity network in Chinese mainland;②Application of superconducting gravity measurement;③Network adjustment for continental-scale gravity survey campaign and data quality control;④Regional time-variable gravity field and its application;⑤Research progress on novel technologies for gravity inversion;⑥Research progress on marine gravity field determination;⑦Application research on marine gravity field. | Heping SUN Lifeng BAO Shi CHEN Xiaoming CUI Qianqian LI Lulu JIA Jianqiao XU Jiangcun ZHOU Minzhang HU Yiqing ZHU Xiaodong CHEN Lin WU Jiancheng HAN Honglei LI Miaomiao ZHANG Linhai WANG | 2023 | Journal of Geodesy and Geoinformation Science2023，6，3： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员