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| 1 | 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents显示文摘Syncope belongs to the transient loss of consciousness(TLOC), characterized by a rapid onset, short duration, and spontaneous complete recovery. It is common in children and adolescents, accounting for 1% to 2% of emergency department visits.Recurrent syncope can seriously affect children's physical and mental health, learning ability and quality of life and sometimes cardiac syncope even poses a risk of sudden death. The present guideline for the diagnosis and treatment of syncope in children and adolescents was developed for guiding a better clinical management of pediatric syncope. Based on the globally recent development and the evidence-based data in China, 2018 Chinese Pediatric Cardiology Society(CPCS) guideline for diagnosis and treatment of syncope in children and adolescents was jointly prepared by the Pediatric Cardiology Society, Chinese Pediatric Society, Chinese Medical Association(CMA)/Committee on Pediatric Syncope, Pediatricians Branch, Chinese Medical Doctor Association(CMDA)/Committee on Pediatric Cardiology, Chinese College of Cardiovascular Physicians, Chinese Medical Doctor Association(CMDA)/Pediatric Cardiology Society, Beijing Pediatric Society, Beijing Medical Association(BMA). The present guideline includes the underlying diseases of syncope in children and adolescents, the diagnostic procedures, methodology and clinical significance of standing test and headup tilt test, the clinical diagnosis vasovagal syncope, postural orthostatic tachycardia syndrome, orthostatic hypotension and orthostatic hypertension, and the treatment of syncope as well as follow-up. | Cheng Wang Yaqi Li Ying Liao Hong Tian Min Huang Xiangyu Dong Lin Shi Jinghui Sun Hongfang Jin Junbao Du Jindou An Jie Chen Mingwu Chen Qi Chen Sun Chen Yonghong Chen Zhi Chen Adolphus Kai-tung Chau Junbao Du Zhongdong Du Junkai Duan Hongyu Duan Xiangyu Dong Lin Feng Lijun Fu Fangqi Gong Yonghao Gui Ling Han Zhenhui Han Bing He Zhixu He Xiufen Hu Yimin Hua Guoying Huang Min Huang Ping Huang Yujuan Huang Hongfang Jin Mei Jin Bo Li Fen Li Tao Li Xiaohui Li Xiaoyan Liu Yan Li Haitao Lv Tiewei Lv Zipu Li Luyi Ma Silin Pan Yusheng Pang Hua Peng Yuming Qin Jie Shen Lin Shi Kun Sun Jinghui Sun Hong Tian Jie Tian Cheng Wang Hong Wang Lei Wang Jinju Wang Wendi Wang Yuli Wang Rongzhou Wu Tianhe Xia Yanyan Xiao Chunhong Xie Yanlin Xing Zhenyu Xiong Baoyuan Xu Yi Xu Hui Yan Shiwei Yang Qijian Yi Xia Yu Xianyi Yu Yue Yuan Hongyan Zhang Huili Zhang Li Zhang Qingyou Zhang Xi Zhang Yanmin Zhang Zhiwei Zhang Cuifen Zhao Bin Zhou Hua Zhu | 2018 | Science Bulletin2018，63，23： | 54 |
| 2 | A promising new class of irradiation tolerant materials:Ti_2ZrHfV_(0.5)Mo_(0.2) high-entropy alloy显示文摘Recently, high-entropy alloys(HEAs) or multi-principal-element alloys with unprecedented physical,chemical, and mechanical properties, have been considered as candidate materials used in advanced reactors due to their promising irradiation resistant behavior. Here, we report a new single-phase bodycentered cubic(BCC) structured Ti_2 ZrHfV_(0.5)Mo_(0.2) HEA possessing excellent irradiation resistance, i.e.,scarcely irradiation hardening and abnormal lattice constant reduction after helium-ion irradiation,which is completely different from conventional alloys. This is the first time to report the abnormal XRD phenomenon of metallic alloys and almost no hardening after irradiation. These excellent properties make it to be a potential candidate material used as core components in next-generation nuclear reactors. The particular irradiation tolerance derives from high density lattice vacancies/defects. | Yiping Lu Hefei Huang Xuzhou Gao Cuilan Ren Jie Gao Huanzhi Zhang Shijian Zheng Qianqian Jin Yonghao Zhao Chenyang Lu Tongmin Wang Tingju Li | 2019 | Journal of Materials Science & Technology2019，35，3： | 23 |
| 3 | Enhancing the strain hardening and ductility of Mg-Y alloy by introducing stacking faults显示文摘Due to the insufficient slip systems,Mg and its alloys exhibit poor ductility during plastic deformation at room temperature.To solve this problem,alloying is considered as a most effective method to improve the ductility of Mg alloys,which attracts wide attentions of industries.However,it is still a challenge to understand the ductilization mechanism,because of the complicated alloying elements and their interactions with Mg matrix.In this work,pure Mg and Mg-Y alloys were comparatively studied to investigate the effect of Y addition on microstructure evolution and mechanical properties.A huge increase of uniform elongation,from 5.3%to 20.7%,was achieved via only 3 wt%addition of yttrium.TEM results revealed that the only activated slip system in pure Mg was basalslip,led to its poor ductility at room temperature.In contrast,a large number of stacking faults and non-basal dislocations withcomponent were observed in the deformed Mg-Y alloy,which was proposed as the main reason for significant improvement of strain hardening and ductility.High resolution TEM indicated that most of the stacking faults were II and 12 intrinsic faults,which played a critical role in improving the ductility of Mg-Y alloy.Addition of Y into Mg alloy decreased the stacking fault energy,which induced high density stacking faults in the grain interior. | Kang Wei Lirong Xiao Bo Gao Lei Li Yi Liu Zhigang Ding Wei Liu Hao Zhou Yonghao Zhao | 2020 | Journal of Magnesium and Alloys2020，8，4： | 8 |
| 4 | Chemical compound cinobufotalin potently induces FOXO1-stimulated cisplatin sensitivity by antagonizing its binding partner MYH9显示文摘In this study,we present novel molecular mechanisms by which FOXO1 functions as a tumor suppressor to prevent the pathogenesis of nasopharyngeal carcinoma(NPC).First,we observed that FOXO1 not only controlled tumor stemness and metastasis,but also sensitized NPC cells to cisplatin(DDP)in vitro and in vivo.Mechanistic studies demonstrated that FOXO1-induced miR-200b expression through the GSK3β/β-catenin/TCF4 network-mediated stimulation of ZEB1,which reduced tumor stemness and the epithelial–mesenchymal transition(EMT)signal.Furthermore,we observed FOXO1 interaction with MYH9 and suppression of MYH9 expression by modulating the PI3K/AKT/c-Myc/P53/miR-133a-3p pathway.Decreased MYH9 expression not only reduced its interactions with GSK3β,but also attenuated TRAF6 expression,which then decreased the ubiquitin-mediated degradation of GSK3βprotein.Increased GSK3βexpression stimulated theβ-catenin/TCF4/ZEB1/miR-200b network,which increased the downstream tumor stemness and EMT signals.Subsequently,we observed that chemically synthesized cinobufotalin(CB)strongly increased FOXO1-induced DDP chemosensitivity by reducing MYH9 expression,and the reduction in MYH9 modulated GSK3β/β-catenin and its downstream tumor stemness and EMT signal in NPC.In clinical samples,the combination of low FOXO1 expression and high MYH9 expression indicated the worst overall survival rates.Our studies demonstrated that CB potently induced FOXO1-mediated DDP sensitivity by antagonizing its binding partner MYH9 to modulate tumor stemness in NPC. | YongHao Li Xiong Liu Xian Lin Menyang Zhao Yanyi Xiao Chen Liu Zixi Liang Zelong Lin Renhui Yi Zibo Tang Jiahao Liu Xin Li Qingping Jiang Libo Li Yinyin Xie Zhen Liu Weiyi Fang | 2019 | Signal Transduction and Targeted Therapy2019，4，1： | 6 |
| 5 | Flexible N-Doped reduced graphene oxide/carbon Nanotube-MnO_(2) film as a Multifunctional Material for High-Performance supercapacitors, catalysts and sensors显示文摘A flexible 3D N-doped reduced graphene oxide(N-RGO)/carbon nanotube(CNT)eMnO_(2) hybrid film was constructed with outstanding supercapacitor,excellent oxygen reduction reaction(ORR)and good sensing performances.The resultant hybrid film possessed large specific capacitances of 418 F g^(-1) and 209 mF cm^(-2) in aqueous and solid electrolytes,and outstanding capacitance retentions of 95% and 94% were obtained for both electrolytes after experiencing 5000 cycles.A simple supercapacitor based on the resultant flexible hybrid film was further fabricated with a much smaller time constant τ0(0.38 s)than that of typical activated-carbon supercapacitors,suggesting a quick response frequency.Moreover,the assembled supercapacitor device showed high energy densities of 45.72 and 92.13 Wh kg^(-1) and simultaneously sustained large power densities of 12,526 and 15873 W kg^(-1) under a scan rate of 50 mV s^(-1) in aqueous and solid electrolytes,respectively.Furthermore,the resultant flexible film showed excellent performance in the ORR and can also be used to assemble a strain sensor with an excellent sensing performance for bending strain. | Chuanyin Xiong Mengrui Li Wei Zhao Chao Duan Yonghao Ni | 2020 | Journal of Materiomics2020，6，3： | 6 |
| 6 | Relationship between full-thickness macular hole and retinal break/lattice degeneration显示文摘Background: The purpose is to investigate the relationship between full-thickness macular hole(MH) and retinal break(RB) and/or lattice degeneration.Methods: Patients diagnosed as full-thickness MH and referred to Dr. Lin Lu from January 2009 to December 2013 were evaluated. All patients underwent general ophthalmologic examinations, fundus examination and optical coherence tomography(OCT). The RB and/or lattice degeneration were recorded.Results: Totally 183 eyes of 167 patients were included. The sex ratio of men to women was 1:2.88. A total of 17 eyes were pseudophakic and 166 eyes were phakic. RB and/or lattice degeneration were found in 62 eyes(33.88%). The prevalence of RB and/or lattice degeneration was similar between men and women(P=0.344>0.05). There was no statistical difference between the pseudophakic eyes and phakic eyes(P=0.138>0.05). All of the RB and/or lattice degeneration were located near or anterior to the equator. The inferior quadrants and the vertical meridian were af ected more often than the superior quadrants and the horizontal meridian.Conclusions: We identified a high incidence of RB/lattice degeneration in cases of full-thickness MH. Carefully examination of the peripheral retina and prophylactic treatment of RB and/or lattice degeneration are critical. | Jinglin Zhang Yonghao Li Xiujuan Zhao Yu Cai Xiling Yu Lin Lu | 2015 | Eye Science2015，30，4： | 2 |
| 7 | Screen printing fabricating patterned and customized full paper-based energy storage devices with excellent photothermal,self-healing,high energy density and good electromagnetic shielding performances显示文摘Supercapacitors are favored by researchers because of their high power density,especially with the acceleration of people’s life rhythm.However,their energy density,especially from the point of view of the whole energy storage device,is far lower than that of commercial batteries.In this work,a kind of customizable full paper-based supercapacitor device with excellent self-healing ability is fabricated by simple and low-cost screen printing,electropolymerization and dip coating methods.The resultant separatorfree supercapacitor device exhibits both ultrahigh gravimetric and areal specific energy(power)densities of 39 Wh kg^(-1)(69 k W kg^(-1))and 692μWh cm^(-2)(236 m W cm^(-2)),achieving excellent supercapacitor performance.Notably,the addition of vitrimers endows the whole device with outstanding self-healing properties,which is helpful for enhancing the adaptability of the device to the environment.In addition,this kind of paper-based device also displays good photothermal and electromagnetic shielding performances.These striking features make paper matrix composites attractive in the fields of supercapacitors,medical photothermal treatment and electromagnetic shielding. | Chuanyin Xiong Mengrui Li Qing Han Wei Zhao Lei Dai Yonghao Ni | 2022 | Journal of Materials Science & Technology2022，，2： | 2 |
| 8 | Microstructural softening induced adiabatic shear banding in Ti-23Nb-0.7Ta-2Zr-O gum metal显示文摘Ti-23Nb-0.7Ta-2Zr-O gum metal(GM)is an attractive candidate material for applications that require superior mechanical properties.In our earlier investigation of the GM[1],geometrical softening and the generation of adiabatic shear bands(ASBs)were proposed as primary reasons for the documented anisotropic impact response.In the present study,electron backscattered diffraction(EBSD)analysis reveals two different deformed microstructures,i.e.,deformed ultrafine grains(UFGs)and dynamically recrystallized UFGs,formed in the ASBs of GM samples processed by extrusion equal channel angular pressing(ECAP),respectively.Additional calculation of temperature rise during dynamic compression suggests that the above microstructure differences in the ASBs was originated from their different maximum ASB temperatures(608 K for extruded GM and 1159 K for ECAP-processed GM).Moreover,our calculation on the temperature at the onset of ASBs indicates that microstructural softening is the primary cause for the development of ASBs in both extruded GM(321 K)and ECAP-processed GM(331 K). | Silu Liu Y.Z.Guo Z.L.Pan X.Z.Liao E.J.Lavernia Y.T.Zhu Q,M,Wei Yonghao Zhao | 2020 | Journal of Materials Science & Technology2020，54，19： | 2 |
| 9 | The C_(6)D_(6)detector system on the Back-n beam line of CSNS显示文摘Introduction The neutron capture cross sections are very important in the field of nuclear device design and basic physics research.Hydrogen-free liquid scintillator such as C_(6)D_(6)detectors are widely used in the neutron capture cross-sectional measurements for the low neutron sensitivity and fast time response.The Back-n white neutron source at China Spallation Neutron Source is the first spallation white neutron source in China,and it is suitable for neutron capture cross-sectional measurement.Materials and methods A C_(6)D_(6)detector system was built in the Back-n experimental station.The pulse height weighting technique was used to determine the system’s detection efficiency.The response to gamma rays of the C_(6)D_(6)detector was measured,and the energy resolution function was determined.Monte Carlo simulation with Geant4 code was carried out to get the weighting function of this C_(6)D_(6)detector system.Additionally,the systematic uncertainty of the weighting function was also determined.Conclusion According to the experimental and simulation results,this C_(6)D_(6)detector system can be used to measure neutron capture cross section. | Jie Ren Xichao Ruan Jie Bao Guangyuan Luan Wei Jiang Qi An Huaiyong Bai Ping Cao Qiping Chen Yonghao Chen Pinjing Cheng Zengqi Cui Ruirui Fan Changqing Feng Minhao Gu Fengqin Guo Changcai Han Zijie Han Guozhu He Yongcheng He Yuefeng He Hanxiong Huang Weiling Huang Xiru Huang Xiaolu Ji Xuyang Ji Haoyu Jiang Hantao Jing Ling Kang Mingtao Kang Bo Li Lun Li Qiang Li Xiao Li Yang Li Yang Li Rong Liu Shubin Liu Xingyan Liu Yinglin Ma Changjun Ning Binbin Qi Zhaohui Song Hong Sun Xiaoyang Sun Zhijia Sun Zhixin Tan Hongqing Tang Jingyu Tang Pengcheng Wang Qi Wang Taofeng Wang Yanfeng Wang Zhaohui Wang Zheng Wang Jie Wen Zhongwei Wen Qingbiao Wu Xiaoguang Wu Xuan Wu Likun Xie Yiwei Yang Han Yi Li Yu Tao Yu Yongji Yu Guohui Zhang Jing Zhang Linhao Zhang Liying Zhang Qingmin Zhang Qiwei Zhang Xianpeng Zhang Yuliang Zhang Zhiyong Zhang Yingtan Zhao Liang Zhou Zuying Zhou Danyang Zhu Kejun Zhu Peng Zhu | 2019 | Radiation Detection Technology and Methods2019，3，3： | 1 |
| 10 | Hydrogen-rich saline reduces cell death through inhibition of DNA oxidativestress and overactivation of poly (ADP-ribose) polymerase-1 in retinal ischemia-reperfusioninjury显示文摘 | Hongwei Liu Ning Hua Keliang Xie Tingting Zhao Yonghao Yu | 2015 | Molecular Medicine Reports2015，，2： | 1 |
| 11 | Multi-platform omics analysis reveals molecular signature for COVID-19 pathogenesis,prognosis and drug target discovery显示文摘Disease progression prediction and therapeutic drug target discovery for Coronavirus disease 2019(COVID-19)are particularly important,as there is still no effective strategy for severe COVID-19 patient treatment.Herein,we performed multi-platform omics analysis of serial plasma and urine samples collected from patients during the course of COVID-19.Integrative analyses of these omics data revealed several potential therapeutic targets,such as ANXA1 and CLEC3B.Molecular changes in plasma indicated dysregulation of macrophage and suppression of T cell functions in severe patients compared to those in non-severe patients.Further,we chose 25 important molecular signatures as potential biomarkers for the prediction of disease severity.The prediction power was validated using corresponding urine samples and plasma samples from new COVID-19 patient cohort,with AUC reached to 0.904 and 0.988,respectively.In conclusion,our omics data proposed not only potential therapeutic targets,but also biomarkers for understanding the pathogenesis of severe COVID-19. | Yuming Li Guixue Hou Haibo Zhou Yanqun Wang Hein Min Tun Airu Zhu Jingxian Zhao Fei Xiao Shanwen Lin Dongdong Liu Dunrong Zhou Lang Mai Lu Zhang Zhaoyong Zhang Lijun Kuang Jiao Guan Qiushi Chen Liyan Wen Yanjun Zhang Jianfen Zhuo Fang Li Zhen Zhuang Zhao Chen Ling Luo Donglan Liu Chunke Chen Mian Gan Nanshan Zhong Jincun Zhao Yan Ren Yonghao Xu | 2021 | Signal Transduction and Targeted Therapy2021，6，5： | 1 |
| 12 | The Effects of Therapeutic Horseback Riding Program on Motor Skills inChildren with Autism Spectrum Disorder显示文摘Therapeutic horseback riding(THR)as an animal-assisted intervention is one of the innovative approaches emer-ging in the treatment for children with autism spectrum disorder(ASD).The current study was designed to inves-tigate the effects of a 12-week,twice a week THR program on motor skills in sixty-eight children with ASD aged 5–10 years old.All participants selected met the DSM-V criteria for ASD,and a total offifty-three participants completed the study.A randomized controlled trial design was utilized for the study.Data was collected via a pre-THR test,interim-THR test,and post-THR test to investigate the possible changes in motor skills throughout the 12-week THR program.Results showed that the THR program significantly improved overall motor skills across time points(p<0.05)and sub-skills of run,gallop and two-hand catch(as compared to the control group,p<0.05).In conclusion,the THR program may be an effective option for improving motor skills in children with ASD and further investigation with a longer period of intervention is warranted. | Mengxian Zhao Yonghao You Jinming Li Sean Healy Alyx Taylor Zhihao Zhang Linlin Li Liye Zou | 2022 | International Journal of Mental Health Promotion2022，24，4： | 1 |
| 13 | Highly ordered large caged cubic mesoporous silica structures templated by triblock PEO-PBO-PEO copolymcr 显示文摘 | YU Chengzhong YU Yonghao ZHAO Dongyuan | 2000 | Chem Commun2000，，7： | 1 |
| 14 | Association of T916C (Y257H) mutation in Candida albicans ERG11 with fluconazole resistance显示文摘 | Jie Zhao Yonghao Xu Chunyang Li | 2012 | Mycoses2012，，3： | 1 |
| 15 | Highly ordered large caged cubic mesoporous silica structures templated by triblock PEO- PBO- PEO copolymer显示文摘 | YU Chengzhong YU Yonghao ZHAO Dongyuan | 2000 | Chem Commun2000，，： | 1 |
| 16 | Secreted IL‐1α promotes T‐cell activation and expansion of CD11b+Gr1+ cells in carbon tetrachloride‐induced liver injury in mice显示文摘 | Dandan Lin Lei Lei Yinsheng Zhang Bo Hu Guangming Bao Yonghao Liu Yuan Song Chunliang Liu Yan Wu Lixiang Zhao Xiao Yu Haiyan Liu | 2015 | Eur. J. Immunol2015，，： | 1 |
| 17 | Scratch- induced deformation in fine- and ultrafine-grained bulk alumina 显示文摘 | Huang Lin Zhang Zhihui Zhao Yonghao | 2010 | Scripta Materialia2010，63，： | 1 |
| 18 | Effects of surface heating on precipitation over the Tibetan Plateau and its eastern margin显示文摘The high terrain of the Tibetan Plateau(TP)has a very important impact on the weather and climate of China,East Asia,South Asia,and even the Northern Hemisphere.However,in recent years,the reasons for the decrease in precipitation in the southeastern edge of the plateau have resulted in cutting-edge research regarding the impact of the TP and its surrounding areas on downstream weather and climate.In this study,the spatial and temporal distribution of surface heat flux and precipitation were analyzed from 1998 to 2022,and the possible mechanism of the decrease of precipitation in the eastern edge of the plateau is explored.The main conclusions are as follows:The annual average sensible heat flux in the TP and its east side is positive,with an average of 33.73 W/m^(2).The annual average latent heat flux is positive,with an average of 42.71 W/m^(2).Precipitation has a similar annual average and seasonal distribution,with modest amounts in the northwest and substantial amounts in the southeast.The average annual accumulated precipitation is 670.69 mm.The first mode of the Empirical Orthogonal Function(EOF)shows that sensible heat flux decreases first,then increases,and then finally decreases during 1998–2022.The modes show the opposite trend in middle part of the plateau.The latent heat flux initially decreases,then increases,and finally decreases in the western plateau and near Sichuan Basin.The mode,however,displays the opposite tendency throughout the rest of the region.The precipitation in the north and south sides of the plateau has decreased since 2013,which is consistent with the changing trend of sensible heat flux.In the rest of the region,the change trend is not obvious.The sensible heat of the main body of the plateau and its east side and Sichuan Basin is negatively correlated with precipitation,that is,when sensible heat flux of the main body of the plateau and its east side and Sichuan Basin is more(less),local precipitation is less(more).The latent heat of the main body of the plateau and its east side,Sichuan Basin is positively correlated with precipitation,indicating that when latent heat flux of the main body of the plateau and its east side,Sichuan Basin is more(less),local precipitation is more(less). | MaoShan Li YuChen Liu Zhao Lv YongHao Jiang Pei Xu YaoMing Ma FangLin Sun | 2023 | Research in Cold and Arid Regions2023，15，5： | 0 |
| 19 | Detector development at the Back-n white neutron source显示文摘Purpose Back-n is a white neutron beamline at China spallation neutron source,which was established in the year of 2018.It is a powerful facility for nuclear data measurement,neutron detector calibration,and radiation effect research.Method A series of detectors were built for different experiments,including beam monitoring,beam profile measurement,neutron induced secondaries(fission fragments,light charged particles and gamma)cross section measurement,and neutron resonance radiography,etc.A common digitization electronics and a cluster-based DAQ were developed for these detector systems.Most detectors have been employed at Back-n and serviced for experiments from the beginning of the beamline running.Results and conclusion As an overview of detectors of Back-n,the details of the detector design and the experiment performing are described in this paper.Some developing systems,e.g.,MTPC and B-MCP,are also included. | Fan Ruirui Li Qiang Bao Jie Li Yang Liu Rong Jiang Wei Ren Jie Zhang Qiwei Cao Ping Gu Minhao Ren Zhizhou Yi Han Tang Jingyu An Qi Bai Haofan Bai Jiangbo Chen Qiping Chen Yonghao Chen Zhen Cui Zengqi Fan Anchuan Feng Changqing Feng Fanzhen Gao Keqing Han Changcai Han Zijie He Guozhu He Yongcheng Hong Yang Hu Yiwei Huang Hanxiong Jia Weihua Jiang Haoyu Jiang Zhijie Jin Zhengyao Kang Ling Li Bo Li Chao Li Gong Li Jiawen Li Xiao Liu Jie Liu Shubin Luan Guangyuan Ning Changjun Qi Binbin Ruan Xichao Song Zhaohui Sun Kang Tan Zhixin Tang Shengda Wang Pengcheng Wang Zhaohui Wen Zhongwei Wu Xiaoguang Wu Xuan Xie Likun Yang Yiwei Yu Yongji Zhang Guohui Zhang Linhao Zhang Mohan Zhang Xianpeng Zhang Yuliang Zhang Yue Zhang Zhiyong Zhao Maoyuan Zhou Luping Zhou Zhihao Zhu Kejun The CSNS Back-n Collaboration | 2023 | Radiation Detection Technology and Methods2023，7，2： | 0 |
| 20 | Enhanced mechanical properties of a carbon and nitrogen co-doped interstitial high-entropy alloy via tuning ultrafine-grained microstructures显示文摘C-N co-doped interstitial high entropy alloy(iHEA)was reported to have high strength and ductility.However,iHEA with fully recrystallized ultrafine grains(UFGs)and underlying thermally activated pro-cesses associated with dislocation slip,twinning,and solute drag have not been reported yet.In this work,a C-N co-doped iHEA with nominal composition Fe_(48.5)Mn_(30)Co_(10)Cr_(10)C_(0.5)N_(1.0)(at.%)was prepared,and the microstructures were tuned by cold-rolling and annealing treatments to improve mechanical properties.Upon cold-rolling with a strain of 1.74,the main microstructures in the iHEA are composed of nano-grains,nano-twins,HCP laminates,and high density of dislocations,leading to ultrahigh hardness of 466.7 HV and tensile strength of 1730 MPa at the expense of ductility(2.44%).Both the nanostructures and the high hardness of the iHEA can be maintained up to an annealing temperature of 600℃(462.5 HV).After annealing at 650℃ for 1 h,the UFG microstructures are obtained in the iHEA,containing re-crystallized grains with an average grain size of 0.91μm and nanoprecipitates with an average diameter of 90.8 nm.The combined strengthening and hardening effects of UFGs,nanoprecipitates,twinning,and solutes contribute to high strain hardening(n=0.81),gigapascal yield strength(984 MPa),and good duc-tility(20%).The C-N co-doping leads to a strong drag effect on dislocation slip,resulting in a nano-scale mean free path of dislocation slip λ(1.44 nm)and much small apparent activation volume V^(∗)(15.8 b^(3))of the UFG iHEA. | Wei Jiang Heng Wang Zhiming Li Yonghao Zhao | 2023 | Journal of Materials Science & Technology2023，，13： | 0 |
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