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| 1 | 体内腺相关病毒-常间回文重复序列丛集及其相关蛋白9介导的基因编辑可改善家族性高胆固醇血症的动脉粥样硬化显示文摘低密度脂蛋白受体(low-density lipoprotein receptor,Ldlr)基因突变是家族性高胆固醇血症的主要原因之一,可导致动脉粥样硬化,并具有很高的终生心血管病风险。常间回文重复序列丛集(clustered regularly interspaced short palindromic repeats,CRISPR)/CRISPR相关蛋白9(CRISPR-related protein 9,Cas9)系统是基因编辑纠正基因突变从而改善疾病的有效工具。该研究的目的是通过腺相关病毒(adeno-associated virus,AAV)携带的CRISPR/Cas9系统进行体内体细胞基因编辑,以确定其能否在小鼠模型中治疗由Ldlr突变体引起的家族性高胆固醇血症。 | 刘青(译) 叶鹏(审校) Zhao H Li Y He L Pu W Yu W Li Y Wu YT Xu C Wei Y Ding Q Song BL Huang H Zhou B | 2020 | 中华高血压杂志2020，28，3： | 22 |
| 2 | The genetic heterozygosity and fitness of tetraploid embryos and embryonic stem cells are crucial parameters influencing survival of mice derived from embryonic stem cells by tetraploid embryo aggregation显示文摘 | Li X Wei W Yong J Jia Q Yu Y Di K | 2006 | 中国生物学文摘2006，20，7： | 3 |
| 3 | Determinants of foreign direct investment across China 显示文摘 | Sun Q Tong W Yu Q | 2002 | Journal of International Money and Finance2002，，21： | 1 |
| 4 | Advanced glycation endproducts induce podocyte apoptosis by activation of the FOXO4 transcription factor显示文摘 | Chuang P Y Yu Q Fang W | 2007 | Kidney Int2007，72，8： | 1 |
| 5 | Enhanced high-potential and elevated-temperature cycling stability of LiMn2O4 cathode by TiO2 modification for Li-ion battery 显示文摘 | Yu L Qiu x xi J Zhu W T Chen L Q | 2006 | Eleetrochimica Acta2006，51，： | 1 |
| 6 | Layered Copper Metagermanate Nanobelts: Hydrothennal Synthesis, Structure, and Magnetic Properties显示文摘 | Song R Q Xu A W Yu S H | 2007 | J Am Chem Soc2007，129，14： | 1 |
| 7 | A novel titanium-supported Ag/Ti electrode for the electro-oxidation of hydrazine 显示文摘 | Yi Q F Li L Yu W Q | 2008 | Journal of Molecular Catalysis A: Chemical2008，295，： | 1 |
| 8 | An investigation of a new near-beta forging process for titanium alloys and its application in aviation components显示文摘 | Zhou Y G Zeng W D Yu H Q | 2005 | Mater Sci Eng A2005，393，1： | 1 |
| 9 | A novel tool to assess systolic asynchrony and identify responders of cardiac resynchronization therapy by tissue synchronization imaging 显示文摘 | YU C M ZHANG Q FUNG J W | 2005 | J Am Coll Cardiol2005，45，5： | 1 |
| 10 | Anti-fatigue activity of polysaccharides extract from Radix Rehmanniae Preparata 显示文摘 | Tan W Yu K Q Liu Y Y | 2012 | Int J Biol Macromol2012，50，1： | 1 |
| 11 | Naked-eye colorimetric analysis of Hg 2+with bi-color CdTe quantum dots multilayer films显示文摘 | Yang F P Ma Q Yu W | 2011 | Talanta2011，84，2： | 1 |
| 12 | 查看详情显示文摘 | Yu Q W ShiZG Lin B | | 0，，： | 1 |
| 13 | Efficiency evaluation of high-temperature steam electrolytic systems coupled with different nuclear reactors显示文摘 | Zhang W Q Yu B Xu J M | | 0，，17： | 1 |
| 14 | Expression pattern genomic struc- ture, and promoter analysis of the gene encoding stilbene synthase from Chinese wild Vitis pseudoreticulata显示文摘 | XU W R YU Y H ZHOU Q DING J H DAI L M XIE X Q XU Y ZHANG C H WANG Y J | 2011 | Journal of Experimen- tal Botany2011，62，8： | 1 |
| 15 | The TIL commissioning and performance显示文摘 | X Zhang W Zheng X Wei F Jing Z Sui K Zheng Q Xu X Yuan X Jiang L Yang P Ma M Li J Wang D Hu S He F Li Z Peng B Feng H Zhou L Guo X Li X Zhang J Su Q Zhu H Yu R Zhao C Ma H He D Fan W Zhang | 2008 | Journal of Physics: Conference Series2008，，3： | 1 |
| 16 | An investigation of a new near - beta forging process for titanium alloys and its application in aviation components 显示文摘 | Zhou Y G Zeng W D Yu H Q | 2005 | Materials Science and Engineering (A)2005，393，： | 1 |
| 17 | The Isolation and Characterization of Lignin of Kenaf Fiber显示文摘 | Yah T T Xu Y Q Yu C W | 2009 | J Appl Polym Sci2009，114，3： | 1 |
| 18 | A novel density-tunable nanoeomposites of CdTe quantum dots linked to dendrimer-tethered multiwall carbon nanotubes显示文摘 | Zeng Y L Tang C R Wang H W Jiang J H Tian M N Shen G L Yu R Q | 2008 | Spectrochimica Acta Part A:Molecular and Biomolecular Spectroscopy2008，70，5： | 1 |
| 19 | In vitro and in vivo neuroprotective effect and mechanisms of glabridin, a major active isoflavan from Glycyr- rhiza glabra (licorice) 显示文摘 | Yu X Q Xue C C Zhou Z W | 2008 | Life Sci2008，82，： | 1 |
| 20 | Thermally stable light- emitting polymers of substituted polyaoetylenes显示文摘 | YU G LIU Y Q ZHAN X W | 2000 | Thin Solid Films2000，363，： | 1 |
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