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| 1 | Ag_(2)Se Complex Nanostructures with Photocatalytic Activity and Superhydrophobicity显示文摘Single-crystalline Ag_(2)Se complex nanostructures have been synthesized via a solvothermal route in which selenophene(C4H4Se)as a selenylation source reacts with AgNO3 at a temperature of 240°C.An orthorhombic phaseβ-Ag_(2)Se nanostructure was identified by X-ray diffraction(XRD),Raman spectroscopy,field emission scanning electron microscopy(FE-SEM),high resolution transmission electron microscopy(HRTEM),and photoluminescence(PL)spectroscopy.The wettability of the as-synthesizedβ-Ag_(2)Se nanostructure was studied by measurement of the water contact angle(CA).Static water CA values of over 150°were obtained,which can be attributed to theβ-Ag_(2)Se complex nanostructure having a combination of micro-and nanostructures.The superhydrophobic Ag_(2)Se nanostructure may find applications in self-cleaning.Additionally,the photocatalytic activity of the as-synthesizedβ-Ag_(2)Se nanostructure was evaluated by photodegradation of rhodamine B(RhB)dye under ultraviolet(UV)light irradiation. | Huaqiang Cao Yujiang Xiao Yuexiang Lu Jiefu Yin Baojun Li Shuisheng Wu Xiaoming Wu | 2010 | Nano Research2010，3，12： | 4 |
| 2 | Dynamic mechanical loading facilitated chondrogenic differentiation of rabbit BMSCs in collagen scaffolds显示文摘Mechanical signals have been played close attention to regulate chondrogenic differentiation of bone marrow mesenchymal stem cells(BMSCs).In this study,dynamic mechanical loading simulation with natural frequencies and intensities were applied to the 3D cultured BMSCs–collagen scaffold constructs.We investigated the effects of dynamic mechanical loading on cell adhesion,uniform distribution,proliferation,secretion of extracellular matrix(ECM)and chondrogenic differentiation of BMSCs–collagen scaffold constructs.The results indicated that dynamic mechanical loading facilitated the BMSCs adhesion,uniform distribution,proliferation and secretion of ECM with a slight contraction,which significantly improved the mechanical strength of the BMSCs–collagen scaffold constructs for better mimicking the structure and function of a native cartilage.Gene expression results indicated that dynamic mechanical loading contributed to the chondrogenic differentiation of BMSCs with higher levels of AGG,COL2A1 and SOX9 genes,and prevented of hypertrophic process with lower levels of COL10A1,and reduced the possibility of fibrocartilage formation due to down-regulated COL1A2.In conclusion,this study emphasized the important role of dynamic mechanical loading on promoting BMSCs chondrogenic differentiation and maintaining the cartilage phenotype for in vitro reconstruction of tissue-engineered cartilage,which provided an attractive prospect and a feasibility strategy for cartilage repair. | Wanxu Cao Weimin Lin Hanxu Cai Yafang Chen Yi Man Jie Liang Qiguang Wang Yong Sun Yujiang Fan Xingdong Zhang | 2019 | Regenerative Biomaterials2019，6，2： | 3 |
| 3 | Effect of valproic acid on endogenous neural stem cell proliferation in a rat model of spinal cord injury显示文摘BACKGROUND:Valproic acid has been reported to decrease apoptosis,promote neuronal differentiation of brain-derived neural stem cells,and inhibit glial differentiation of brain-derived neural stem cells. OBJECTIVE:To investigate the effects of valproic acid on proliferation of endogenous neural stem cells in a rat model of spinal cord injury. DESIGN,TIME AND SETTING:A randomized,controlled,neuropathological study was performed at Key Laboratory of Trauma,Burrning,and Combined Injury,Research Institute of Surgery,Daping Hospital,the Third Military Medical University of Chinese PLA between November 2005 and February 2007. MATERIALS:A total of 45 adult,Wistar rats were randomly divided into sham surgery(n=5),injury (n=20),and valproic acid(n=20) groups.Valproic acid was provided by Sigma,USA. METHODS:Injury was induced to the T_(10) segment in the injury and valproic acid groups using the metal weight-dropping method.The spinal cord was exposed without contusion in the sham surgery group.Rats in the valproic acid group were intraperitoneally injected with 150 mg/kg valproic acid every 12 hours(twice in total). MAIN OUTCOME MEASURES:Nestin expression(5 mm from injured center) was detected using immunohistochemistry at 1,3 days,1,4,and 8 weeks post-injury. RESULTS:Low expression of nestin was observed in the cytoplasm,but rarely in the white matter of the spinal cord in the sham surgery group.In the injury group,nestin expression was observed in the ependyma and pia mater one day after injury,and expression reached a peak at 1 week(P<0.05). Expression was primarily observed in the ependymal cells,which expanded towards the white and gray matter of the spinal cord.Nestin expression rapidly decreased by 4 weeks post-injury,and had almost completely disappeared by 8 weeks.At 24 hours after spinal cord injury,there was no significant difference in nestin expression between the valproic acid and injury groups.At 1 week, there was a significant increase in the number of nestin-positive cells surrounding the central canal in valproic acid group compared with the injury group(P<0.05).Expression reached a peak by 4 weeks,and it was still present at 8 weeks. CONCLUSION:Valproic acid promoted endogenous neural stem cell proliferation following spinal cord injury in rats. | Guoxin Nan Ming Li Weihong Liao Jiaqiang Qin Yujiang Cao Youqiong Lu | 2009 | Neural Regeneration Research2009，4，7： | 1 |
| 4 | The synthesis and photocatalytic activity of ZnSe microspheres 显示文摘 | Cao Huaqiang Xiao Yujiang Zhang Sichun | 2011 | Nanotechnology2011，22，1： | 1 |
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