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| 1 | Transmission and mortality risk assessment of severe fever with thrombocytopenia syndrome in China:results from 11-years’study显示文摘Background: The transmission and fatal risk of severe fever with thrombocytopenia syndrome (SFTS), an emerging infectious disease first discovered in China in 2009, still needed further quantification. This research aimed to analyze the SFTS clusters and assess the transmission and mortality risk for SFTS.Methods: Both epidemiological investigation and case reports regarding SFTS clusters in China during 2011-2021 were obtained from the Public Health Emergency Information Management System of the Chinese Center for Disease Control and Prevention Information System. The transmission risk was evaluated by using the secondary attack rate (SAR) and relative risk (RR). Mortality risk factors were analyzed using a logistic regression model.Results: There were 35 SFTS clusters during 2011-2021 involving 118 patients with a fatality rate of 22.0%. The number of clusters annually increased seasonally from April to September. The clusters mainly occurred in Anhui (16 clusters) and Shandong provinces (8 clusters). The SAR through contact with blood or bloody fluids was much higher than that through contact with non-bloody fluids (50.6% vs 3.0%;χ^(2) = 210.97,P < 0.05), with anRR of 16.61 [95% confidence interval (CI): 10.23-26.97]. There was a statistically significant difference in the SAR between exposure to the blood of a deceased person during burial preparation and exposure to the living patients’ blood (66.7% vs 34.5%;χ^(2)= 6.40,P < 0.05), with anRR of 1.93 (95%CI: 1.11-3.37). The mortality risk factors were a long interval from onset to diagnosis [odds ratio (OR)= 1.385), 95%CI: 1.083-1.772,P= 0.009) and advanced age (OR: 1.095, 95%CI: 1.031-1.163,P= 0.01).Conclusions: The SFTS clusters showed a high mortality rate and resulted in a high SAR. Contact with a bleeding corpse was associated with a higher infection risk, compared with contacting the blood from living patients. It is important to promote early detection and appropriate case management of patients with SFTS, as well as improved handling of their corpses, to prevent further transmission and mortality. | Qiulan Chen Dong Yang Yanping Zhang Mantong Zhu Ning Chen Zainawudong Yushan | 2022 | Infectious Diseases of Poverty2022，11，5： | 2 |
| 2 | One-step preparation of branched PEG functionalized AIE-active luminescent polymeric nanoprobes显示文摘The synthesis of amphiphilic aggregation-induced emission(AIE) dyes based organic nanoparticles has recently attracted increasing attention in the biomedical fields. These AIE dyes based nanoparticles could effectively overcome the aggregation caused quenching effect of conventional organic dyes, making them promising candidates for fabrication of ultrabright organic luminescent nanomaterials. In this work, AIE-active luminescent polymeric nanoparticles(4-NH_2-PEG-TPE-E LPNs) were facilely fabricated through Michael addition reaction between tetraphenylethene acrylate(TPE-E) and 4-arm-poly(ethylene glycol)-amine(4-NH_2-PEG) in rather mild ambient. The 4-NH_2-PEG can not only endow these AIE-active LPNs good water dispersibility, but also provide functional groups for further conjugation reaction. The size, morphology and luminescent properties of 4-NH_2-PEG-TPE-E LPNs were characterized by a series of techniques in detail. Results suggested that these AIE-active LPNs showed spherical morphology with diameter about 100–200 nm. The obtained 4-NH_2-PEG-TPE-E LPNs display high water dispersibility and strong fluorescence intensity because of their self assembly and AIE properties of TPE-E.Biological evaluation results demonstrated that 4-NH_2-PEG-TPE-E LPNs showed negative toxicity toward cancer cells and good fluorescent imaging performance. All of these features make 4-NH_2-PEG-TPE-E LPNs promising candidates for biological imaging and therapeutic applications. | Jun Chu Qiulan Lv Chunliang Guo Dazhuang Xu Ke Wang Meiying Liu Hongye Huang Xiaoyong Zhang Yen Wei | 2016 | Science China Chemistry2016，59，8： | 2 |
| 3 | Design of an Index System for Deep Groundwater Management Efficiency Evaluation: A Case Study in Tianjin City, China显示文摘An effective evaluation system can provide specific and practical suggestions to the deep groundwater management. But such kind of evaluation system has not been proposed in China. In this study, an evaluation index system is specifically developed to evaluate deep groundwater management efficiency. It is composed of three first-level indicators(law enforcement capability, management ability, and management effectiveness) and eleven second-level indicators. The second-level indicators include seven mandatory indicators and four optional indicators. Piecewise linear function is used to normalize the quantitative indicators, and expert scoring method and questionnaire survey method are used to normalize the qualitative indicators. Then a comprehensive indicator weighting evaluation method is used to evaluate the first-level indicators and the target topic. A case study is carried out to evaluate deep groundwater management efficiency in Tianjin City. According to the evaluation score in each period, the management efficiency of every district in Tianjin City gradually improved. The overall evaluation score in the early deep groundwater extraction period is 0.12. After a series of deep groundwater protection efforts, this score reached to 0.61 in 2007, and met the regulation criteria. The evaluation results also showed that the further groundwater management efforts in Tianjin City should be focused on building a dynamic database to collect comprehensive deep well-log data; and on a reasonable design and distribution of the groundwater monitoring network. It demonstrated that the index system is suitable to locate the deficiencies of current groundwater management systems and to guide further improvements. It can then be used to protect deep groundwater. | NAN Tian SHAO Jingli CAO Xiaoyuan ZHANG Qiulan CUI Yali | 2016 | Chinese Geographical Science2016，26，3： | 1 |
| 4 | Awareness Towards Rabies and Exposure Rate and Treatment of Dog-Bite Injuries Among Rural Residents—Guangxi Zhuang Autonomous Region,China,2021显示文摘Summary What is already known about this topic?Although fatal once clinical signs appear,rabies is preventable through three proven,effective interventions including mass dog vaccination,postexposure prophylaxis(PEP),and,though sometimes neglected,awareness of rabies.What is added by this report?The total awareness rate of rabies-related knowledge among rural residents was only 57.9%in Guangxi Zhuang Autonomous Region,one of the provinciallevel administrative divisions(PLADs)with endemic rabies in China. | Mantong Zhu Di Mu Qiulan Chen Ning Chen Yanping Zhang Wenwu Yin Yu Li Yingjie Chen Yidan Deng Xianyan Tang | 2021 | China CDC weekly2021，3，53： | 1 |
| 5 | Molecular spectroscopic studies on the interaction between Ractopamine and bovine serum albumin显示文摘 | Qiulan Zhang Yongnian Ni Serge Kokot | 2010 | Journal of Pharmaceutical and Biomedical Analysis2010，52，： | 1 |
| 6 | A strong converse inequality for left gamma quasi-interpolants in L p-spaces显示文摘 | Shunsheng Guo Lixia Liu Qiulan Qi Gengsheng Zhang | 2004 | Acta Mathematica Hungarica (-)2004，，1： | 1 |
| 7 | Assessing Impacting Factors of Dog Owners’Adoption of Dog Vaccination Against Rabies:A Cross-sectional Survey in Rural Areas—Guangxi Zhuang Autonomous Region,China,2021显示文摘Summary What is already known about this topic?Rabies is fatal while preventable.More than 99%of human rabies cases were caused by dog bites worldwide.Mass dog vaccination could interrupt dogmediated rabies if achieving and maintaining a minimum coverage rate of 70%.What does this report contribute?The results of this study show that roughly 23.7%of households owned dogs in Guangxi Zhuang Autonomous Region. | Ning Chen Qiulan Chen Yanping Zhang Mantong Zhu Wenwu Yin Di Mu Yu Li Yingjie Chen Yidan Deng Xianyan Tang | 2021 | China CDC weekly2021，3，42： | 0 |
| 8 | Investigation of Brucellosis Caused by Raw Goat Milk—Fujian Province,China,April–June,2019显示文摘Summary What is already known about this topic?Brucellosis is one of the most important zoonotic diseases in China.Goat milk and dairy products are essential pathways for foodborne transmission of brucellosis.Pasteurization can completely kill Brucella spp.in milk,and milk-borne transmission is mainly related to unhealthy dietary hygiene habits and insufficient epidemic control among animals. | Mu Di Zhongfa Tao Weiping Hua Jiandong Chen Jingming Cao Yanqin Deng Huihui Liu Lijie Zhang Yishan Chen Qiulan Chen Wenwu Yin | 2021 | China CDC weekly2021，3，20： | 0 |
| 9 | Construction of isolated Ni sites on nitrogen-doped hollow carbon spheres with Ni-N_(3) configuration for enhanced reduction of nitroarenes显示文摘Designing and synthesizing high-efficiency non-precious metal-based catalysts having uniform active sites increases the reactivity and selectivity of materials and provides a platform for an in-depth understanding of their catalytic reaction mechanism.In this study,we provided an approach for fabricating isolated nickel single-atom sites(Ni SAs)with high loading(4.9 wt.%)stabilized on nitrogen-doped hollow carbon spheres(NHCS)using a core–shell structured Zn/Ni bimetallic zeolitic imidazolate framework(ZIF)composite as the sacrificial template.The as-fabricated Ni SAs/NHCS catalyst shows superior activity,selectivity,and recycling durability for the catalytic transfer hydrogenation of nitrobenzene to aniline,thus achieving 100%yield of aniline with a turn-over frequency(TOF)value as high as 29.9 h^(−1) under mild conditions.This TOF value is considerably superior to the supported Ni nanoparticle catalysts.The experiments designed show that the hollow structure feature of NHCS facilitates accessible active sites and mass transfer,which thus contributes to the enhancement of the catalytic performance of Ni SAs/NHCS.Density functional theory calculations show the high chemo-selectivity and activity of the Ni SAs catalyst,arising from the unique role of the single Ni-N3 site on simultaneously activating the H donor(N_(2)H_(4))and substrate,as well as the hydrogenation of the–NOH group as the rate-determining step. | Binbin Feng Rou Guo Qiulan Cai Yaping Song Nan Li Yanghe Fu De-Li Chen Jiangwei Zhang Weidong Zhu Fumin Zhang | 2022 | Nano Research2022，15，7： | 0 |
| 10 | Toxic effects of pesticides on the marine microalga Skeletonema costatum and their biological degradation显示文摘Pesticides are considered to be toxic pollutants that are harmful to the health of humans and animals or dangerous to the environment.The pesticides chlorpyrifos,acetochlor,and dicofol,representatives of organophosphorus,acyl amide,and organochlorine pesticides,are widely used in agriculture and have been frequently detected in aquatic environments.However,the toxicity of these pesticides to marine microbes is unclear.In this study,the toxic effects of the three pesticides on a representative marine microalga,the diatom Skeletonema costatum(S.costatum),were investigated.Microalgal cell density and chlorophyll-a(Chl-a)content were analyzed to investigate the toxic effects after S.costatum was exposed to the three pesticides both individually and in combination.The N/P ratio in the culture medium and the degradation of the pesticides were also analyzed during exposure.Individual acute toxicity analysis indicated that the growth of S.costatum was significantly inhibited by acetochlor,followed by the effect of dicofol and chlorpyrifos.The cell membrane of the microalgae was impaired by acetochlor.Combined toxicity analysis indicated that the presence of acetochlor increased the toxicity of dicofol and chlorpyrifos.In contrast,the presence of dicofol reduced the toxicity of acetochlor and chlorpyrifos.The N/P ratio in the culture medium was largely increased at late growth stages;however,it was significantly lowered when the microalgae were exposed to chlorpyrifos compared to acetochlor and dicofol.The degradation of the pesticides was promoted by microalgae,suggesting that microalgae might contribute to the removal of these pesticides from the marine environment.The toxic mechanism of the pesticides on the marine microalgae and the fates of pesticides in the ocean need to be further studied. | Zilian ZHANG Qiulan CHEN Bo CHEN Taojie DONG Meng CHEN | 2023 | Science China Earth Sciences2023，66，3： | 0 |
| 11 | Contamination Identification of Lentinula Edodes Logs Based on Improved YOLOv5s显示文摘In order to improve the accuracy and efficiency of Lentinula edodes logs contamination identification,an improved YOLOv5s contamination identification model for Lentinula edodes logs(YOLOv5s-CGGS)is proposed in this paper.Firstly,a CA(coordinate attention)mechanism is introduced in the feature extraction network of YOLOv5s to improve the identifiability of Lentinula edodes logs contamination and the accuracy of target localiza-tion.Then,the CIoU(Complete-IOU)loss function is replaced by an SIoU(SCYLLA-IoU)loss function to improve the model’s convergence speed and inference accuracy.Finally,the GSConv and GhostConv modules are used to improve and optimize the feature fusion network to improve identification efficiency.The method in this paper achieves values of 97.83%,97.20%,and 98.20%in precision,recall,and mAP@0.5,which are 2.33%,3.0%,and 1.5%better than YOLOv5s,respectively.mAP@0.5 is better than YOLOv4,Ghost-YOLOv4,and Mobilenetv3-YOLOv4(improved by 4.61%,5.16%,and 6.04%,respectively),and the FPS increased by two to three times. | Xuefei Chen Wenhui Tan Qiulan Wu Feng Zhang Xiumei Guo Zixin Zhu | 2023 | Intelligent Automation & Soft Computing2023，37，9： | 0 |
| 12 | Optimizing Spatial Relationships in GCN to Improve the Classification Accuracy of Remote Sensing Images显示文摘Semantic segmentation of remote sensing images is one of the core tasks of remote sensing image interpretation.With the continuous develop-ment of artificial intelligence technology,the use of deep learning methods for interpreting remote-sensing images has matured.Existing neural networks disregard the spatial relationship between two targets in remote sensing images.Semantic segmentation models that combine convolutional neural networks(CNNs)and graph convolutional neural networks(GCNs)cause a lack of feature boundaries,which leads to the unsatisfactory segmentation of various target feature boundaries.In this paper,we propose a new semantic segmentation model for remote sensing images(called DGCN hereinafter),which combines deep semantic segmentation networks(DSSN)and GCNs.In the GCN module,a loss function for boundary information is employed to optimize the learning of spatial relationship features between the target features and their relationships.A hierarchical fusion method is utilized for feature fusion and classification to optimize the spatial relationship informa-tion in the original feature information.Extensive experiments on ISPRS 2D and DeepGlobe semantic segmentation datasets show that compared with the existing semantic segmentation models of remote sensing images,the DGCN significantly optimizes the segmentation effect of feature boundaries,effectively reduces the noise in the segmentation results and improves the segmentation accuracy,which demonstrates the advancements of our model. | Zimeng Yang Qiulan Wu Feng Zhang Xuefei Chen Weiqiang Wang XueShen Zhang | 2023 | Intelligent Automation & Soft Computing2023，，7： | 0 |
| 13 | Effects of Exogenous NO on Active Oxygen Metabolism in Cucumber Seedlings under NaCl Stress显示文摘Employing nutrient solution hydroponic method,the effects of exogenous nitric oxide(NO)on the growth and active oxygen metabolism in cucumber(Cucumis sativus L.)seedlings under NaCl stress were investigated.The results indicated that NaCl treatment significantly inhibited the growth of cucumber seedlings,while exogenous NO could significantly alleviate the inhibitory effects of NaCl stress on seedling growth.Especially,0.1 mmol/L SNP treatment exhibited better effects than 0.5 mmol/L SNP treatment on alleviating NaCl stress.Under 0.1 mmol/L NaCl stress,adding 0.1 mmol/L exogenous NO could significantly decrease the generation rate of O·-2and MDA content,significantly improve soluble protein content and enhance the activities of SOD,POD and CAT,thus reducing the damage of salt stress to cucumber seedlings. | Aihui ZHANG Shinong ZHU Qiulan YANG Jingjing LU | 2014 | Agricultural Biotechnology2014，3，3： | 0 |
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