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| 1 | Crimped nanofiber scaffold mimicking tendon-to-bone interface for fatty-infiltrated massive rotator cuff repair显示文摘Electrospun fibers,with proven ability to promote tissue regeneration,are widely being explored for rotator cuff repairing.However,without post treatment,the microstructure of the electrospun scaffold is vastly different from that of natural extracellular matrix(ECM).Moreover,during mechanical loading,the nanofibers slip that hampers the proliferation and differentiation of migrating stem cells.Here,electrospun nanofiber scaffolds,with crimped nanofibers and welded joints to biomimic the intricate natural microstructure of tendon-to-bone insertion,were prepared using poly(ester-urethane)urea and gelatin via electrospinning and double crosslinking by a multi-bonding network densification strategy.The crimped nanofiber scaffold(CNS)features bionic tensile stress and induces chondrogenic differentiation,laying credible basis for in vivo experimentation.After repairing a rabbit massive rotator cuff tear using a CNS for 3 months,the continuous translational tendon-to-bone interface was fully regenerated,and fatty infiltration was simultaneously inhibited.Instead of micro-CT,μCT was employed to visualize the integrity and intricateness of the three-dimensional microstructure of the CNS-induced-healed tendon-to-bone interface at an ultra-high resolution of less than 1μm.This study sheds light on the correlation between nanofiber post treatment and massive rotator cuff repair and provides a general strategy for crimped nanofiber preparation and tendon-to-bone interface imaging characterization. | Liren Wang Tonghe Zhu Yuhao Kang Jianguang Zhang Juan Du Haihan Gao Sihao Chen Jia Jiang Jinzhong Zhao | 2022 | Bioactive Materials2022，7，10： | 2 |
| 2 | Effect of microarc discharge surface treatment on the tensile properties of Al–Cu–Mg alloy显示文摘 | Wenbin Xue Chao Wang Yongliang Li Zhiwei Deng Ruyi Chen Tonghe Zhang | 2002 | Materials Letters2002，，5： | 2 |
| 3 | Electrical properties of polymer modified by metal ion implantation显示文摘 | Wu Yuguang Zhang Tonghe Zhang Huixing | 2000 | Nuclear Instrument and Methods in Physics Research2000，169，： | 1 |
| 4 | Influence of the structure of implanted steel, with Y,Y+ C and Y+Cr on the behaviors of wear, oxidation and corrosion resistance 显示文摘 | Zhang Tonghe Xie Jindong Ji chengzhou | 1995 | Surface and Coatings Technology1995，72，12： | 1 |
| 5 | Surface modification of steel by high-dose pulse-ion implantation of titanium, tungsten, molybdenum and carbon 显示文摘 | Zhang Tonghe Ji Cbengzhou Sben Jinghua | 1991 | Nuclear Instruments and Methods in Physiscs Research1991，，5960： | 1 |
| 6 | Growth Regularity of Ceramic Coatings Formed by Microarc Oxidation on Al-Cu-Mg Alloy 显示文摘 | XUE Wenbin DENG Zhiwei CHEN Ruyi ZHANG Tonghe | 2000 | Thin Solid Films2000，372，1： | 1 |
| 7 | Effect of microarc discharge surface treatment on the tensile properties of Al–Cu–Mg alloy显示文摘 | Wenbin Xue Chao Wang Yongliang Li Zhiwei Deng Ruyi Chen Tonghe Zhang | 2002 | Materials Letters2002，，5： | 1 |
| 8 | Growth regularity of ceramic coatings formed by microarc oxidation on Al–Cu–Mg alloy显示文摘 | Wenbin Xue Zhiwei Deng Ruyi Chen Tonghe Zhang | 2000 | Thin Solid Films2000，，1： | 1 |
| 9 | 显示文摘 | Zhang Tonghe Ji Chengzhou Shen Jinghua | 1993 | Nucl In-strum Methods1993，72，： | 1 |
| 10 | Formation of intermetallic compounds with a high flux pulse molybdenum ion beam in steel and aluminum显示文摘 | Zhang Tonghe Ji Chengzhou Yang Jianhua | 1994 | Surface and Coatings Technology1994，65，： | 1 |
| 11 | Corrosion behavior of the embedded layer with nanometer phase in Ti and Ti +C implanted steel显示文摘 | Zhang Tonghe Wu Yuguang | 2000 | Nucl Instrum Meth2000，169，： | 1 |
| 12 | Formation of the nanometer embedded phase during high energy Ti- implanted and annealed steel显示文摘 | Zhang Tonghe Wu Yuguang | 2000 | Nud Instrum Meth2000，169，： | 1 |
| 13 | MEVVA ion source development and its industrial application at Beijing Normal University 显示文摘 | Liu Andong Zhang Huixing Zhang Tonghe | 2005 | Surface & Coatings Technology2005，193，： | 1 |
| 14 | Industrialization of MEWA source ion implantion 显示文摘 | Zhang Huixing | 2000 | Surf Coat Technol2000，，128： | 1 |
| 15 | Industrialization of MEWA source ion implantation显示文摘 | Zhang Tonghe Zhang Huixing | 2000 | Surface and Coatings Technology2000，1281，： | 1 |
| 16 | Formation of nanometer embedded phase during high - energy Ti - implanted and annedealed steel 显示文摘 | Wu Yuguang | 2000 | Nucl Instrum Methods2000，，169： | 1 |
| 17 | Behavior of MEVVA metal ion implantation for surface modification of materials显示文摘 | Zhang Tonghe Wang Xiaoyan | 1996 | Surface and Coatings Technology1996，83，： | 1 |
| 18 | Formation of intermetallic compounds with a high flux pulse molybdenum ion beam in steel and aluminium显示文摘 | Zhang Tonghe Ji Chengzhou Yang Jianhua | 1992 | Surface and Coatings Technology1992，51，123： | 1 |
| 19 | Formation of intermetallic compounds with a high flux pulse molybdenum ion beam in steel and aluminum 显示文摘 | Zhang Tonghe Ji Chengzhou Yang Jianhua | 1992 | Surf Coat Tech1992，51，： | 1 |
| 20 | 显示文摘 | Zhang Tonghe Wang Xiaoyou Liang Hong | 1996 | Surf Coat and Tech1996，83，： | 1 |
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