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| 1 | A seven-gene-deleted African swine fever virus is safe and effective as a live attenuated vaccine in pigs显示文摘African swine fever(ASF)is a devastating infectious disease in swine that is severely threatening the global pig industry.An efficacious vaccine is urgently required.Here,we used the Chinese ASFV HLJ/18 as a backbone and generated a series of genedeleted viruses.The virulence,immunogenicity,safety,and protective efficacy evaluation in specific-pathogen-free pigs,commercial pigs,and pregnant sows indicated that one virus,namely HLJ/18-7GD,which has seven genes deleted,is fully attenuated in pigs,cannot convert to the virulent strain,and provides complete protection of pigs against lethal ASFV challenge.Our study shows that HLJ/-18-7GD is a safe and effective vaccine against ASFV,and as such is expected to play an important role in controlling the spread of ASFV. | Weiye Chen Dongming Zhao Xijun He Renqiang Liu Zilong Wang Xianfeng Zhang Fang Li Dan Shan Hefeng Chen Jiwen Zhang Lulu Wang Zhiyuan Wen Xijun Wang Yuntao Guan Jinxiong Liu Zhigao Bu | 2020 | Science China(Life Sciences)2020,63,5: | 72 |
| 2 | Emergence and prevalence of naturally occurring lower virulent African swine fever viruses in domestic pigs in China in 2020显示文摘African swine fever virus(ASFV)has been circulating in China for more than two years,and it is not clear whether the biological properties of the virus have changed.Here,we report on our surveillance of ASFVs in seven provinces of China,from June to December,2020.A total of 22 viruses were isolated and characterized as genotype II ASFVs,with mutations,deletions,insertions,or short-fragment replacement occurring in all isolates compared with Pig/HLJ/2018(HLJ/18),the earliest isolate in China.Eleven isolates had four different types of natural mutations or deletion in the EP402R gene and displayed a nonhemadsorbing(non-HAD)phenotype.Four isolates were tested for virulence in pigs;two were found to be as highly lethal as HLJ/18.However,two non-HAD isolates showed lower virulence but were highly transmissible;infection with 106 TCID50 dose was partially lethal and caused acute or sub-acute disease,whereas 103 TCID50 dose caused non-lethal,sub-acute or chronic disease,and persistent infection.The emergence of lower virulent natural mutants brings greater difficulty to the early diagnosis of ASF and creates new challenges for ASFV control. | Encheng Sun Zhenjiang Zhang Zilong Wang Xijun He Xianfeng Zhang Lulu Wang Wenqing Wang Lianyu Huang Fei Xi Haoyue Huangfu Ghebremedhin Tsegay Hong Huo Jianhong Sun Zhijun Tian Wei Xia Xuewu Yu Fang Li Renqiang Liu Yuntao Guan Dongming Zhao Zhigao Bu | 2021 | Science China(Life Sciences)2021,64,5: | 46 |
| 3 | Plate subduction, oxygen fugacity, and mineralization显示文摘Plate subduction is the largest natural factory that processes elements,which controls recycling and mineralization of a variety of elements.There are three major ore deposit belts in the world:the circumPacific,the centralAsian,and the Tethys belts.All the three belts are closely associated with plate subductions,the mechanism remains obscure.We approached this problem from systematic studies on the behaviours of elements during geologic processes.This contribution summaries the recent progress of our research group.Our results suggest that porphyry Cu deposits form through partial melting of subducted young oceanic crust under oxygen fugacities higher than AFMQ^+1.5,which is promoted after the elevation of atmospheric oxygen at ca.550 Ma.Tin deposits are associated with reducing magmatic rocks formed as a consequence of slab rollback.The Neo-Tethys tectonic regime hosts more than 60%of the world's total Sn reserves.This is due to the reducing environment formed during the subduction of organic rich sediments.For the same reason,porphyry Cu deposits formed in the late stages during the closure of the Neo-Tethys Ocean.Tungsten deposits are also controlled by slab rollback,but is not so sensitive to oxygen fugacity.Subduction related W/Sn deposits are mostly accompanied by abundant accessory fluorites due to the breakdown of phengite and apatite.Decomposition of phengite is also significant for hard rock lithium deposits,whereas orogenic belt resulted from plate subduction promote the formation of Li brine deposits.Cretaceous red bed basins near the Nanling region are favorable for Li brines.Both Mo and Re are enriched in the oxidationreduction cycle during surface processes,and may get further enriched once Mo-,Re-enriched sediments are subducted and involved in magmatism.During plate subduction,Mo and Re fractionate from each other.Molybdenum is mainly hosted in porphyry Mo deposits and to a less extent,porphyry Cu-Mo deposits,whereas Re is predominantly hosted in porphyry Cu-Mo deposits and sedimentary sulfide deposits. | LIU He LIAO Renqiang ZHANG Lipeng LI Congying SUN Weidong | 2020 | Journal of Oceanology and Limnology2020,38,1: | 10 |
| 4 | Advances in the Studies of the Middle and Upper Atmosphere in 2004 - 2006显示文摘This paper summarizes the research results obtained by Chinese scientists and/or through international collaborations during 2004 to 2006. Within the context of COSPAR, the progresses in the studies of the middle and upper atmosphere in China in the past two years are introduced with focusing the developments in facilities and instruments, and the advancements in scientific issues, e.g., dynamics related processes, atmospheric constituents, and the coupling with the lower atmosphere. | CHEN Zeyu LIU Renqiang CHEN Hongbin CHEN Wen LU Daren XU Jiyao HU Xiong | 2006 | 空间科学学报2006,26,z1: | 6 |
| 5 | Plate convergence in the Indo-Pacific region显示文摘The Indo-Pacific convergence region is the best target to solve the teo remaining challenges of the plate tectonics theory,i.e.,subduction initiation and the driving force of plate tectonics.Recent studies proposed that the Izu-Bonin subduction initiation belongs to spontaneous initiation,which implies that it started from extension,followed by low angle subduction.Numerical geodynamic modeling suggests that the initiation of plate subduction likely occurred along a transform fault,which put the young spreading ridge in direct contact with old oceanic crust.This,however,does not explain the simultaneous subduction initiation in the west Pacific region in the Cenozoic.Namely,the subduction initiations in the Izu-BoninMariana,the Aleutian,and the Tonga-Kermadec trenches are associated with oceanic crusts of different ages,yet they occurred at roughly the same time,suggesting that they were all triggered by a maj or change in the Pacific plate.Moreover,low angle subduction induces compression rather than extension,which requires external compression forces.Given that the famous Hawaiian-Emperor bending occurred roughly at the same time with the onset of westward subductions in the west Pacific,we propose that these Cenozoic subductions were initiated by the steering of the Pacific plate,which are classified as induced initiation.Induced subduction initiation usually occurs in young ocean basins,forming single-track subduction.The closure s of Neo-Tethys Oceans were likely triggered by plume s in the south,forming northward subductions.Interestingly,the Indian plate kept on moving northward more than 50 Ma after the collision between the Indian and Eurasian continents and the break-off of the subducted oceanic slab attached to it.This strongly suggests that slab pull is not the main driving force of plate tectonics,whereas slab sliding is. | SUN Weidong ZHANG Lipeng LIAO Renqiang SUN Saijun LI Congying LIU He | 2020 | Journal of Oceanology and Limnology2020,38,4: | 4 |
| 6 | Hardware-in-the-loop simulation for the contact dynamic process of flying objects in space显示文摘在地面上的一个严肃环境,自从人首先由飞目标探索了空间,在空间的零严肃的环境的二个飞的目标的接触过程的模拟是一个挑战性的问题。Hardware-in-the-loop (HIL ) 模拟是一个重要、有效的方法在空间测试真实停靠机制的可用性,可靠性,和安全。为 HIL 模拟系统有四个主要问题:能够高频率反应,高运动精确,高速度,和快速的加速的模拟器的设计;为模拟失真的赔偿;为 HIL 模拟进程的一个控制模型的设计;并且试验性的确认。这里,我们与 6-DOF 3-3 建议一个新奇 HIL 模拟器系统垂直平行机制和 3-DOF 3-PRS 平行机制;发现模拟失真的原则;为模拟器的力量测量系统,动态反应,和结构的动力学介绍失真赔偿模型;并且为 HIL 模拟过程提供一个控制模型。二种实验在被动未受潮的有弹性的杆和停靠机制上被执行测试他们的表演并且验证 HIL 模拟器的有效性和可用性。在这份报纸建议的 HIL 模拟系统为开发停靠的空格是有用的, berthing, refueling,修理,升级,搬运,并且 rescuing 技术。 | GAO Feng QI ChenKun REN AnYe ZHAOXianChao CAO Rui SUN Qiao WANG Qian HU Yan HE Jun JIN ZhenLin LIU RenQiang ZHANG Yong GUO WeiZhong HU ZhenYu TANG Ping NI Bo JING QianFeng WANG WeiJun GAO Peng | 2016 | Science China(Technological Sciences)2016,59,8: | 4 |
| 7 | Novel P22-monoclonal antibody based blocking ELISA for the detection of African swine fever virus antibodies in serum显示文摘African swine fever(ASF)is a highly infectious,transboundary viral disease of domestic and wild pigs,and is currently the most serious threat to world swine production,resulting in significant economic loss.In the absence of vaccines and treatments,the control of the disease entirely depends on accurate and early diagnosis accompanied by the culling of infected pigs.Thus,a highly specific and sensitive diagnostic assay is required during an outbreak and surveillance of the disease.In this study,a highly sensitive,specific,rapid and repeatable P22-monoclonal antibody-based blocking enzyme-linked immunosorbent assay(bELISA)assay was developed for the detection of antibodies against genotype I and II African swine fever viruses(ASFVs).A total of 806 pig serum samples were tested to evaluate the performance of the diagnostic assay.To determine the PI(percent Inhibition)cut-off value,receiver-operating characteristic(ROC)analysis was applied.According to the ROC analysis of the data,98.10%specificity and 100%sensitivity were recorded when the threshold cut-off value of PI was established at 47%.In addition,the assay was able to detect ASFV antibodies as early as 9 days post-infection when serum samples from experimentally infected pigs were used.Taking all together,the results of the present study indicated that the P22-mAb based bELISA assay can be used for rapid and accurate detection of antibodies against ASFV,which could play a valuable role in the containment and prevention of ASFV as an alternative to other serological diagnostic methods.Also,this study will assist researchers to further investigate the immunogenic importance of P22 protein in ASFV infection. | Ghebremedhin Tsegay Weldu Tesfagaber Yuanmao Zhu Xijun He Wan Wang Zhenjiang Zhang Encheng Sun Jinya Zhang Yuntao Guan Fang Li Renqiang Liu Zhigao Bu Dongming Zhao | 2022 | Biosafety and Health2022,4,4: | 2 |
| 8 | Double cores of the Ozone Low in the vertical direction over the Asian continent in satellite data sets显示文摘Using four satellite data sets(TOMS/SBUV, OMI, MLS, and HALOE), we analyze the seasonal variations of the total column ozone(TCO) and its zonal deviation(TCO*), and reveal the vertical structure of the Ozone Low(OV) over the Asian continent. Our principal findings are:(1) The TCO over the Asian continent reaches its maximum in the spring and its minimum in the autumn. The Ozone Low exists from May to September.(2) The Ozone Low has two negative cores, located in the lower and the upper stratosphere. The lower core is near 30 hPa in the winter and 70 hPa in the other seasons. The upper core varies from 10 hPa to 1 hPa among the four seasons.(3)The position of the Ozone Low in the lower and the upper stratosphere over the Asian continent shows seasonal variability. | Zhou Tang Dong Guo YuCheng Su ChunHua Shi ChenXi Zhang Yu Liu XiangDong Zheng WenWen Xu JianJun Xu RenQiang Liu WeiLiang Li | 2019 | Earth and Planetary Physics2019,3,2: | 1 |
| 9 | Replication,pathogenicity,and transmission of SARS-CoV-2 in minks显示文摘Minks are raised in many countries and have transmitted severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)to humans.However,the biologic properties of SARS-CoV-2 in minks are largely unknown.Here,we investigated and found that SARS-CoV-2 replicates efficiently in both the upper and lower respiratory tracts,and transmits efficiently in minks via respiratory droplets;pulmonary lesions caused by SARS-CoV-2 in minks are similar to those seen in humans with COVID-19.We further found that a spike protein-based subunit vaccine largely prevented SARS-CoV-2 replication and lung damage caused by SARS-CoV-2 infection in minks.Our study indicates that minks are a useful animal model for evaluating the efficacy of drugs or vaccines against COVID-19 and that vaccination is a potential strategy to prevent minks from transmitting SARS-CoV-2. | Lei Shuai Gongxun Zhong Quan Yuan Zhiyuan Wen Chong Wang Xijun He Renqiang Liu Jinliang Wang Qinjian Zhao Yuxiu Liu Ningning Huo Junhua Deng Jingjing Bai Hongchao Wu Yuntao Guan Jianzhong Shi Kegong Tian Ningshao Xia Hualan Chen Zhigao Bu | 2021 | National Science Review2021,8,3: | 1 |
| 10 | Eimeria tenella:Expression profiling of toll-like receptors and associated cytokine in the cecum of infected day-old and three-week old SPF chickens Experimental显示文摘 | Lei Zhang Renqiang Liu Liping Ma | 2012 | Parasitology2012,130,2: | 1 |
| 11 | Resonant nonlinear interactions between atmospheric waves in the polar summer mesopause region显示文摘 | Renqiang Liu Fan Yi | 2003 | Science in China Series G: Physics Mechanics and Astronomy2003,,4: | 1 |
| 12 | Geochemistry of subducted metabasites exhumed from the Mariana forearc:Implications for Pacific seamount subduction显示文摘Seamounts on the drifting oceanic crust are inevitably carried by plate motions and eventually accreted or subducted.However,the geochemical signatures of the subducted seamounts and the significance of seamount subduction are not well constrained.Hundreds of seamounts have subducted beneath the Philippine Sea Plate following the westward subduction of the Pacific Plate since the Eocene(~52 Ma).The subducted oceanic crust and seamount materials can be exhumed from the mantle depth to the seafloor in the Mariana forearc region by serpentinite mud volcanoes,providing exceptional opportunities to directly study the subducted oceanic crust and seamounts.The International Ocean Discovery Program(IODP)expedition 366 has recovered a few metamorphosed mafic clasts exhumed from the Mariana forearc serpentinite mud volcanoes,e.g.,the Fantangis?a and Asùt Tesoru seamounts.These mafic clasts have tholeiitic to alkaline affinities with distinct trace elements and Nd-Hf isotopes characteristics,suggesting different provenances and mantle sources.The tholeiites from the Fantangisna Seamount have trace element characteristics typical of mid-ocean ridge basalt.The Pacific-type Hf-Nd isotopic compositions,combined with the greenschist metamorphism of these tholeiites further suggest that they came from the subducted Pacific oceanic crust.The alkali basalts-dolerites from the Fantangisna and Asùt Tesoru seamounts show ocean island basalt(OIB)-like geochemical characteristics.The OIB-like geochemical signatures and the low-grade metamorphism of these alkali basalts-dolerites suggest they came from subducted seamounts that originally formed in an intraplate setting on the Pacific Plate.The Pacific Plate origin of these metabasites suggests they were formed in the Early Cretaceous or earlier.Two types of OIBs have been recognized from alkali metabasites,one of which is geochemically similar to the HIMU-EMI-type OIBs from the West Pacific Seamount Province,and another is similar to the EMII-type OIBs from the Samoa Island in southern Pacific,with negative Nb-Ta-Ti anomalies and enriched Nd-Hf isotopes.Generally,these alkali metabasites are sourced from the heterogeneous mantle sources that are similar to the present South Pacific Isotopic and Thermal Anomaly.This study provides direct evidence for seamount subduction in the Mariana convergent margins.We suggest seamount subduction is significant to element cycling,mantle heterogeneity,and mantle oxidation in subduction zones. | Jianghong Deng Lipeng Zhang He Liu Haiyang Liu Renqiang Liao Abdul Shakoor Mastoi Xiaoyong Yang Weidong Sun | 2021 | Geoscience Frontiers2021,12,3: | 1 |
| 13 | Resonant nonlinear interactions between atmospheric waves in the polar summer mesopause region显示文摘 | Renqiang Liu Fan Yi | 2003 | Science in China Series G: Physics Mechanics and Astronomy2003,,4: | 1 |
| 14 | Eimeria tenella : Expression profiling of toll-like receptors and associated cytokines in the cecum of infected day-old and three-week old SPF chickens显示文摘 | Lei Zhang Renqiang Liu Liping Ma Yingwei Wang Baoliang Pan Jianping Cai Ming Wang | 2012 | Experimental Parasitology2012,,4: | 1 |
| 15 | An innovative three-layer strategy in response to a quartan malaria outbreak among forest goers in Hainan Island,China:a retrospective study显示文摘Background:An outbreak of Plasmodium malariae infection among forest goers in Sanya City of Hainan Island,China was reported in 2015.In response to this outbreak,an innovative three-layer strategy(TLS)targeted forest goers was adapted based on the 1-3-7 approach.Main text:Key elements of TLS are:(i)The village with fve malaria cases and adjacent villages were set as the frst layer.All residents including forest goers were taken as the high-risk population(HRP).Active case detection(ACD)by blood smear microscopy and PCR was selected as the primary measure,and passive case detection(PCD)as complementary measure.One case was identifed under TLS implementation.(ii)The township with cases(Gaofeng Town)and the nearby towns were chosen as the second layer.Only forest goers were screened by ACD,while PCD as a routine screening method.7831 blood smears collected by ACD and PCD and tested with negative results.(iii)The city with cases(Sanya City)and others 12 counties/county-level cities were selected as the third layer.Malaria cases were monitored passively.A total of 77,555 blood slides were screened by PCD with zero positive sample.For each layer,the malaria vector mosquitoes were monitored using light traps,cattle-baited/human-bait traps.Anopheles minimus(dominant species),An.sinensis and An.dirus were captured.Vector control measures mainly include insecticide residual spraying and long-lasting insecticide nets.The capacity of clinicians,public health practitioners and laboratory technicians has been improved through training.During 2016‒2018,TLS and chemoprophylaxis were implemented in the same areas.In the frst layer,all residents were monitored by ACD,and malaria chemoprophylaxis were distributed,89.5%of forest goers were using chemoprophylaxis against malaria.The blood smears(3126 by ACD plus 1516 by PCD)were with zero positive results.Chemoprophylaxis and ACD were ofered to forest goers once a year,and PCD in residents as a complementary measure in the second and third layer,77.8%and 95.1%of forest goers received chemoprophylaxis.In each layer,vector surveillance and control of malaria and trainings for medical staf Conclusions:TLS was efective in blocking the outbreak by P.malariae among forest goers in Hainan in malaria elimination stage.However,whether it could prevent the malaria resurgence in the post-elimination phase needs to be further assessed. | Yuchun Li Yingjuan Huang Renqiang Chen Weizhen Huang Huanzhi Xu Rongshen Ye Shaoling Huang Ji Zhen Xiaodan Wen Guoyi Wang Yong Liu Haishan Li Zaichun Zheng Jian Wang Guoshen Wang Chong Chen Wen Zeng Feng Meng Xiaoming Huang Guangze Wang Bing Yang Yan Chen | 2022 | Infectious Diseases of Poverty2022,11,5: | 0 |
| 16 | Immunogenicity of a recombinant VSV-Vectored SARS-CoV vaccine induced robust immunity in rhesus monkeys after single-dose immunization显示文摘Severe acute respiratory syndrome(SARS)is a highly contagious zoonotic disease caused by SARS coronavirus(SARS-Co V).Since its outbreak in Guangdong Province of China in 2002,SARS has caused 8096 infections and774 deaths by December 31st,2003.Although there have been no more SARS cases reported in human populations since 2004,the recent emergence of a novel coronavirus disease(COVID-19)indicates the potential of the recurrence of SARS and other coronavirus disease among humans.Thus,developing a rapid response SARS vaccine to provide protection for human populations is still needed.Spike(S)protein of SARS-Co V can induce neutralizing antibodies,which is a pivotal immunogenic antigen for vaccine development.Here we constructed a recombinant chimeric vesicular stomatitis virus(VSV)VSVΔG-SARS,in which the glycoprotein(G)gene is replaced with the SARS-Co V S gene.VSVΔG-SARS maintains the bullet-like shape of the native VSV,with the heterogeneous S protein incorporated into its surface instead of G protein.The results of safety trials revealed that VSVΔG-SARS is safe and effective in mice at a dose of 1×10^(6)TCID_(50).More importantly,only a single-dose immunization of 2×10^(7)TCID_(50)can provide high-level neutralizing antibodies and robust T cell responses to non-human primate animal models.Thus,our data indicate that VSVΔG-SARS can be used as a rapid response vaccine candidate.Our study on the recombinant VSV-vectored SARS-Co V vaccines can accumulate experience and provide a foundation for the new coronavirus disease in the future. | Dan Shan Xiaoyan Tang Renqiang Liu Dan Pan Xijun Wang Jinying Ge Zhiyuan Wen Zhigao Bu | 2022 | Virologica Sinica2022,37,2: | 0 |
| 17 | Single cell RNA and immune repertoire prowling of COVID-19 patients reveal novel neutralizing antibody显示文摘There is no doubt that COVID-19 outbreak is currently the biggest public health threat,which has caused catastrophic con sequences in many countries and regions.As host immunity is key to fighting against virus infection,it is important to characterize the immunologic changes in the COVID-19 patients,and to explore potential therapeutic candidates.The most efficient ways to end this pandemic are to vaccinate the susceptible population,and to use specific drugs,such as monoclonal antibodies against the viral spike protein(S protein),to treat the affected individuals.Several promising neutralizing antibodies have recently been reported(Cao et al.,2020;Lv et al.,2020). | Fang Li Meng Luo Wenyang Zhou Jinliang Li Xiyun Jin Zhaochun Xu Liran Juan Zheng Zhang Yuou Li Renqiang Liu Yiqun Li Chang Xu Kexin Ma Huimin Cao Jingwei Wang Pingping Wang Zhigao Bu Qinghua Jiang | 2021 | Protein & Cell2021,12,10: | 0 |
| 18 | Advances in the Researches of the Middle and Upper Atmosphere in China显示文摘In this paper we summarize the research results by Chinese scientists in 2016–2018. The focuses are placed on the researches of the middle and upper atmosphere, specifically the researches associated with groundbased observation capability development, dynamical processes, and properties of circulation and chemistryclimate coupling of the middle atmospheric layers. | CHEN Zeyu CHEN Hongbin XU Jiyao L Daren ZHANG Shaodong XUE Xianghui TIAN Wenshou LIU Renqiang CHEN Wen HU Yongyun WANG Rui HU Dingzhu HU Xiong YANG Guotao GONG Yun LU Gaopeng | 2018 | 空间科学学报2018,38,5: | 0 |
| 19 | Efcient soluble PTCBI‑type non‑fullerene acceptor materials for organic solar cells显示文摘Single perylene diimide(PDI)used as a non-fullerene acceptor(NFA)in organic solar cells(OSCs)is enticing because of its low cost and excellent stability.To improve the photovoltaic performance,it is vital to narrow the bandgap and regulate the stacking behavior.To address this challenge,we synthesize soluble perylenetetracarboxylic bisbenzimidazole(PTCBI)molecules with a bulky side chain at the bay region,by replacing the widely used“swallow tail”type alkyl chains at the imide position of PDI molecules with a planar benzimidazole structure.Compared with PDI molecules,PTCBI molecules exhibit red-shifted UV–vis absorption spectra with larger extinction coefcient,and one magnitude higher electron mobility.Finally,OSCs based on one soluble PTCBI-type NFA,namely MAS-7,exhibit a champion power conversion efciency(PCE)of 4.34%,which is signifcantly higher than that of the corresponding PDI-based OSCs and is the highest PCE of PTCBI-based OSCs reported.These results highlight the potential of soluble PTCBI derivatives as NFAs in OSCs. | Xiang Gao Fengbo Sun Xinzhu Tong Xufan Zheng Yinuo Wang Cong Xiao Pengcheng Li Renqiang Yang Xunchang Wang Zhitian Liu | 2023 | Frontiers of Optoelectronics2023,16,2: | 0 |
| 20 | Subtle Side Chain Triggers Unexpected Two-Channel Charge Transport Property Enabling 80%Fill Factors and Efficient Thick-Film Organic Photovoltaics显示文摘To clearly show how important the impact of side chains on organic solar cells(OSCs)is,we designed three acceptors IDIC-CxPh(x=4,5,or 6)via subtle side-chain regulation.Despite this small change,significant distinctions were detected.IDIC-C4Ph devices achieve an optimal efficiency of 13.94%under thermal annealing,but thermal-assistant solvent-vapor annealing hugely suppresses the efficiencies to 10%.However,the C6Ph side chain endows extremely disordered stacking orientations,generating moderate efficiencies of~12.50%.Excitingly,the IDIC-C5Ph affords an unexpected two-channel p-p charge transport(TCCT)property,boosting the fill factor(FF)by up to 80.02%and efficiency to 14.56%,ranking the best among five-ring fused-ladder-type acceptors.Impressively,the special TCCT behavior of IDIC-C5Ph enables 470 nm thick-film OSC with a high FF of up to 70.12%and efficiency of 13.01%,demonstrating the great promise in fabricating largescale OSCs. | Yonghai Li Lu Yu Liangliang Chen Chenyu Han Huanxiang Jiang Zitong Liu Nan Zheng Jiuxing Wang Mingliang Sun Renqiang Yang Xichang Bao | 2021 | The Innovation2021,2,1: | 0 |