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| 1 | Screening for main components associated with the idiosyncratic hepatotoxicity of a tonic herb, Polygonum multiflorum显示文摘典型药用的植物的主要成分,蓼 multiflorum (用汉语的 Heshouwu ) ,那导致特质的肝损害仍然保持不清楚。我们的以前的工作证明了有 lipopolysaccharide (LPS ) 的无毒的剂量和 Heshouwu 的治疗学的剂量的 cotreatment 能在老鼠导致肝损害,而独唱治疗不能导致看得见的损害。在现在的工作,用成分大美人和敲门在里面策略,我们发现 Heshouwu 的乙醇醋酸盐(EA ) 摘录在对待 LPS 的老鼠显示了可比较的特质的 hepatotoxicity 到整个摘录。结果显示血浆丙氨酸 aminotransferase, aspartate aminotransferase,和肝 histologic 的重要举起变化,而另外的分开的部分没能导致肝损害。有另外的分开的部分的 EA 摘录的混合在对待 LPS 的老鼠导致了可比较的特质的 hepatotoxicity 到整个摘录。化学分析进一步揭示了那 2,3,5,4-tetrahydroxy trans-stilbene-2-O -- 配糖物(trans-SG ) 和它的 cis 异构体是在 EA 的二主要混合物摘录。而且,孤立的 cis- ,并且不它的 trans 异构体,显示的可比较的特质的 hepatotoxicity 到在对待 LPS 的老鼠的 EA 摘录。cis-SG 的更高的内容从与收集的将军相比与 Heshouwu 联系的实际的肝沉醉病人在 Heshouwu 白酒或准备被检测样品。另外,血浆 metabolomics 分析证明 cis-SG-disturbing 充实显著地不同于的小径在对待 LPS 的老鼠的 trans-SG。所有这些结果建议 cis-SG 仔细与 Heshouwu 的特质的 hepatotoxicity 被联系。认为 trans-SG 的 cis-trans 异构化被紫外光或日光调停,我们的调查结果为在药发现控制 photoisomerization 并且为 Heshouwu 和芪相关的药的临床的使用用作参考。 | Chunyu Li Ming Niu Zhaofang Bai Congen Zhang Yanling Zhao Ruiyu Li Can Tu Huifang Li Jing Jing Yakun Meng Zhijie Ma Wuwen Feng Jinfa Tang Yun Zhu Jinjie Li Xiaoya Shang Zhengsheng Zou Xiaohe Xiao Jiabo Wang | 2017 | Frontiers of Medicine2017，11，2： | 41 |
| 2 | Synchronization of two coupled exciters in a vibrating system of spatial motion显示文摘纸建议调查二的同步的一条分析途径在空间运动的一个颤动的系统联合了 exciters。为二 exciters 的平均尖速度介绍骚乱参数,我们推出二 exciters,联合矩阵的惯性在是对称的尖速度的非维的联合方程并且联合矩阵的僵硬在一个非反响的颤动系统是反对称的。阶段角度的联合余弦效果将引起对二台马达起作用限制二 exciters 之间的阶段差别的增加以及在跑期间支撑它二 exciters 的对称的转矩的动态典型表演处理的联合的分析。它身体上解释二 exciters 的自我同步的怪癖。颤动的阶段角度的余弦效果由每 exciter 愿望减少使它惯性的时刻激动。每 exciter 的惯性的剩余时刻代表它惯性的相对时刻。 exciters 是二 exciters 的惯性的相对非维的时刻都比乘他们的产品的零和四伟大的二的同步的稳定性条件比他们阶段角度的联合余弦效果的系数的平方大,它等价于联合矩阵的惯性是积极的明确并且所有它的元素是积极的。数字结果证明颤动的系统的结构能保证同步操作的稳定性条件。关键词频率俘获-稳定性-同步-颤动的系统-振动同步传播工程被辽宁省学院科学和研究( 2008S095 )支持,中国的国家自然科学基础的关键工程( 50535010 , 50805020 )并且中国( 2007AA04Z442 )的高技术研究和开发节目。 | Chunyu Zhao Hongtao Zhu Yimin Zhang Bangchun Wen | 2010 | Acta Mechanica Sinica2010，26，3： | 25 |
| 3 | Observation of mega-dune evaporation after various rain events in the hinterland of Badain Jaran Desert, China显示文摘The formation mechanisms of the mega-dunes and lakes in the hinterland of Badain Jaran Desert,China,is the focus of extensive academic research in the field of geoscience,and an often debated topic is whether atmospheric precipitation on the mega-dune can infiltrate to recharge groundwater.In the present study,the probability distribution functions and the return period analysis of extreme daily precipitation based on long-term precipitation records for the southern margin of Badain Jaran Desert and 2-year observation of hinterland precipitation were used to classify precipitation in the desert region.The data of automatic weather station and eddy covariance system in the desert hinterland were used to analyze evaporation on the mega-dune surface after various rain events.The results showed that the rain events in the desert could be divided into three categories.The first is conventional precipitation(CP),which is below 5 mm,accounting for roughly 90%of all rain events in the desert.The second and third categories are ordinary annual maximum(OAM)and extreme precipitation(EP),in which precipitation is roughly 20 mm and more than 40 mm,respectively.The atmospheric precipitation of CP and OAM evaporated from the megadune surface in 1–3 days and 3–4 weeks,respectively.Following an EP event,the mega-dune evaporation was negatively influenced by the upper dry sand layer,and a lengthy period was required for its complete removal.The accumulative evaporation and accumulative precipitation of all three types of rain events indicated that local atmospheric precipitation had no significant contribution to recharging the groundwater system in the hinterland of Badain Jaran Desert.This research will benefit comprehensive elucidation of the formation mechanism of lakes in the hinterland of Badain Jaran Desert. | Ning Ma Naiang Wang Liqiang Zhao Zhenyu Zhang Chunyu Dong Shiping Shen | 2014 | Chinese Science Bulletin2014，59，2： | 14 |
| 4 | Eleven COVID-19 Outbreaks with Local Transmissions Caused by the Imported SARS-CoV-2 Delta VOC-China,July-August,2021显示文摘Starting from December 2019,Wuhan,China,encountered the first outbreak of coronavirus disease 2019(COVID-19)(1-2).The epidemic was successfully suppressed by strict containment so that the number of infected people was reduced to 0 on April 8,2020(3–4).After that,China experienced roughly 3 dozen outbreaks with local transmission caused by imported severe acute respiratory syndrome coronavirus 2(SARS-CoV-2). | Lei Zhou Kai Nie Hongting Zhao Xiang Zhao Bixiong Ye Ji Wang Cao Chen Hong Wang Jiangli Di Jinsong Li Chao Li Zhixiao Chen Ruiqi Ren Peihua Niu Hui Chen Tao Chen Yali Wang Lili Li Bingxue Han Ruhan A Si Chen Dan Li Dan Li Chunxia Jin Xin Zhang Jiangmei Liu Chunyu Xu Yecheng Yao Yenan Feng Zhili Li Bike Zhang Yang Song Peter Hao Yanping Zhang Hao Li Qun Li George F.Gao Guoqing Shi Wenbo Xu | 2021 | China CDC weekly2021，3，41： | 13 |
| 5 | Synchronization of the four identical unbalanced rotors in a vibrating system of plane motion显示文摘A new mechanism is proposed to implement the synchronization of the four unbalanced rotors in a vibrating system, which consists of a main rigid frame (MRF) and two accessorial rigid frames (ARF). An analytical approach is developed to study the coupling dynamic characteristics of the four unbalanced rotors, which converts the problem of synchronization of the four unbalanced rotors into the existence and the stability of zero solutions for the non-dimensional differential equations of the angular velocity disturbance parameters (NDDEDP). The stability of zero solutions of the NDDEDP is decomposed into that of its generalized system and a system of the three first order differential equations for the disturbance parameters of the phase differences. The coupling dynamic characteristic of the four unbalanced rotors includes the inertia coupling, the stiffness coupling of angular velocity and the load torque coupling. The non-dimensional inertia coupling matrix is symmetric, the non dimensional matrix of the stiffness coupling of angular velocity is antisymmetric and its diagonal elements are all negative. Hence, the general system of the NDDEDP automatically satisfies the generalized Lyapunov equations when the non-dimensional inertia coupling matrix is positive definite and its elements are all positive. Using Routh-Hurwitz criterion the condition of stability of differential equations for the disturbance parameters of the phase differences is obtained. The load torque coupling makes the vibrating system have the dynamic characteristic of selecting motions and self-synchronization of the four unbalanced rotors arises from the dynamic characteristic of selecting motion of the vibrating system. When the two coefficients of coupling cosine effect of phase angles are all greater than 0 and the three indexes of synchronization are all far greater than 1, the vibrating system can implement an elliptical motion of the main rigid frame required in engineering. Numeric results show that the structural parameters of the proposed mechanism can guarantee the non-dimensional inertia matrix to be always positive definite. Computer simulation is carried out to verify the results of the theoretical investigation. | ZHAO ChunYu, WEN BangChun & ZHANG XueLiang School of Mechanical Engineering and Automation, Northeastern University, Shenyang 110004, China | 2010 | Science China(Technological Sciences)2010，53，2： | 12 |
| 6 | A point mutation resulting in a 13 bp deletion in the coding sequence of Cldf leads to a GA-deficient dwarf phenotype in watermelon显示文摘The dwarf architecture is an important and valuable agronomic trait in watermelon breeding and has the potential to increase fruit yield and reduce labor cost in crop cultivation.However,the molecular basis for dwarfism in watermelon remains largely unknown.In this study,a recessive dwarf allele(designated as Cldf(Citrullus lanatus dwarfism))was fine mapped in a 32.88 kb region on chromosome 09 using F2 segregation populations derived from reciprocal crossing of a normal line M08 and a dwarf line N21.Gene annotation of the corresponding region revealed that the Cla015407 gene encoding a gibberellin 3β-hydroxylase functions as the best possible candidate gene for Cldf.Sequence analysis showed that the fourth polymorphism site(a G to A point mutation)at the 3′AG splice receptor site of the intron leads to a 13 bp deletion in the coding sequence of Cldf in dwarf line N21 and thus results in a truncated protein lacking the conserved domain for binding 2-oxoglutarate.In addition,the dwarf phenotype of Cldf could be rescued by exogenous GA3 application.Phylogenetic analysis suggested that the small multigene family GA3ox(GA3 oxidase)in cucurbit species may originate from three ancient lineages in Cucurbitaceae.All these data support the conclusion that Cldf is a GA-deficient mutant,which together with the cosegregated marker can be used for breeding new dwarf cultivars. | Chunhua Wei Chunyu Zhu Liping Yang Wei Zhao Rongxue Ma Hao Li Yong Zhang Jianxiang Ma Jianqiang Yang Xian Zhang | 2019 | Horticulture Research2019，6，1： | 12 |
| 7 | Bavachin enhances NLRP3 inflammasome activation induced by ATP or nigericin and causes idiosyncratic hepatotoxicity显示文摘Psoraleae Fructus(PF)is a well-known traditional herbal medicine in China,and it is widely used for osteoporosis,vitiligo,and other diseases in clinical settings.However,liver injury caused by PF and its preparations has been frequently reported in recent years.Our previous studies have demonstrated that PF could cause idiosyncratic drug-induced liver injury(IDILI),but the mechanism underlying its hepatotoxicity remains unclear.This paper reports that bavachin isolated from PF enhances the specific stimuli-induced activation of the NLRP3 inflammasome and leads to hepatotoxicity.Bavachin boosts the secretion of IL-ip and caspase-1 caused by ATP or nigericin but not those induced by poly(I:C),monosodium urate crystal,or intracellular lipopolysaccharide.Bavachin does not affect AIM2 or NLRC4 inflammasome activation.Mechanistically,bavachin specifically increases the production of nigericin-induced mitochondrial reactive oxygen species among the most important upstream events in the activation of the NLRP3 inflammasome.Bavachin increases the levels of aspartate transaminase and alanine aminotransferase in serum and hepatocyte injury accompanied by the secretion of IL-ip via a mouse model of lipopolysaccharide-mediated susceptibility to IDILI.These results suggest that bavachin specifically enhances the ATP-or nigericin-induced activation of the NLRP3 inflammasome.Bavachin also potentially contributes to PF-induced idiosyncratic hepatotoxicity.Moreover,bavachin and PF should be evaded among patients with diseases linked to the ATP-or nigericin-mediated activation of the NLRP3 inflammasome,which may be a dangerous factor for liver injury. | Nan Qin Guang Xu Yan Wang Xiaoyan Zhan Yuan Gao Zhilei Wang Shubin Fu Wei Shi Xiaorong Hou Chunyu Wang Ruisheng Li Yan Liu Jiabo Wang Haiping Zhao Xiaohe Xiao Zhaofang Bai | 2021 | Frontiers of Medicine2021，15，4： | 9 |
| 8 | Effect of N fertilization rate on soil alkalihydrolyzable N, subtending leaf N concentration,fiber yield, and quality of cotton显示文摘Soil alkali-hydrolyzable nitrogen, which is sensitive to N fertilization rate, is one of the indicators of soil nitrogen supplying capacity. Two field experiments were conducted in Dongtai(120°19″ E, 32°52″ N), Jiangsu, China in 2009 and Dafeng(120°28″ E, 33°12″ N), Jiangsu province, China in 2010. Six nitrogen rates(0, 150, 300, 375, 450, and 600 kg ha^(-1)) were used to study the effect of N fertilization rate on soil alkali-hydrolyzable nitrogen content(SAHNC), subtending leaf nitrogen concentration(SLNC), yield, and fiber quality. In both Dongtai and Dafeng experiment station, the highest yield(1709 kg ha^(-1)), best quality(fiber length 30.6 mm, fiber strength 31.6 c N tex^(-1), micronaire 4.82), and highest N agronomic efficiency(2.03 kg kg^(-1)) were achieved at the nitrogen fertilization rate of 375 kg ha^(-1). The dynamics of SAHNC and SLNC could be simulated with a cubic and an exponential function,respectively. The changes in SAHNC were consistent with the changes in SLNC. Optimal average rate(0.276 mg day^(-1)) and duration(51.8 days) of SAHNC rapid decline were similar to the values obtained at the nitrogen rate of 375 kg ha^(-1)at which cotton showed highest fiber yield, quality, and N agronomic efficiency. Thus, the levels and strategies of nitrogen fertilization can affect SAHNC dynamics. The N fertilization rate that optimizes soil alkali-hydrolyzable nitrogen content would optimize the subtending leaf nitrogen concentration and thereby increase the yield and quality of the cotton fiber. | Binglin Chen Hongkun Yang Weichao Song Chunyu Liu Jiao Xu Wenqing Zhao Zhiguo Zhou | 2016 | The Crop Journal2016，4，4： | 8 |
| 9 | An Improved Hilbert Curve for Parallel Spatial Data Partitioning显示文摘一条新奇 Hilbert 曲线为划分的平行空间数据被介绍,与空间信息和向量数据项的可变长度的特征的巨大数量的性质的考虑。基于改进 Hilbert 弯曲,算法能被设计空间数据在平行空间数据库在多重磁盘之中划分完成几乎制服。因此,数据不平衡的现象能显著地被避免,搜索和询问效率能被提高。 | MENG Lingkui HUANG Changqing ZHAO Chunyu LIN Zhiyong | 2007 | Geo-Spatial Information Science2007，10，4： | 7 |
| 10 | Mesenteric lymph reperfusion may exacerbate brain injury in a rat model of superior mesenteric artery occlusion shock显示文摘BACKGROUND:The intestinal lymphatic pathway and intestinal ischemia/reperfusion are mainly involved in mesenteric lymph duct ligation or drainage;moreover,intervention by reducing the lymph liquid reflux might relieve lung and other organ dysfunction induced by intestinal ischemia/reperfusion;however,research addressing mesenteric lymph reperfusion (MLR) and brain injury has not yet to be reported.OBJECTIVE:To observe the effect of MLR on brain tissue in a rat model of superior mesenteric artery occlusion (SMAO) shock,and to explore the molecular mechanism of MLR.DESIGN,TIME AND SETTING:A randomized,controlled,animal experiment at a neuro-pathophysiology level was performed at the Institute of Microcirculation,Hebei North University;Department of Pathophysiology,Basic Medical College;Department of Pathology,the First Hospital of Hebei North University between December 2007 and March 2009.MATERIALS:Adenosine triphosphate (ATP) standard was provided by the National Institute for the Control of Pharmaceutical and Biological Products;lactic acid (LA),superoxide dismutase (SOD),malonaldehyde (MDA),nitrogen monoxidum (NO),nitric oxide synthase (NOS),myeloperoxidase (MPO) and ATPase assay kits were provided by Nanjing Jiancheng Bioengineering Institute,China.METHODS:A total of 24 male Wistar rats were randomly divided into four groups.In the sham-surgery group (n=6),both the mesenteric lymph duct and the superior mesenteric artery were not blocked;in the MLR group (n=6),the mesenteric lymph duct was occluded for 1 hour followed by 2-hour reperfusion;in the SMAO group (n=6),the superior mesenteric artery was occluded for 1 hour followed by 2-hour reperfusion;in the MLR + SMAO group (n=6),both the mesenteric lymph duct and superior mesenteric artery were occluded for 1 hour followed by 2-hour reperfusion.MAIN OUTCOME MEASURES:Mean arterial blood pressure prior to and following ischemia/reperfusion;brain tissue morphology levels of LA,MDA,SOD,NO,NOS,MPO,ATPase and ATP following reperfusion.RESULTS:MLR did not cause changes in mean arterial blood pressure,brain tissue morphology,LA,MDA,NO,ATP,SOD,NOS,MPO and ATPase.However,SMAO caused a rapid decrease and gradual increase of mean arterial blood pressure.Neuronal necrosis,degeneration and swelling were observed in brain tissue.Contents of MDA,NO,LA and ATP as well as activities of NOS and MPO were significantly increased (P < 0.05),but activities of SOD and Na+-K+-ATPase were significantly decreased (P < 0.05).MLR aggravated neuronal damage in a rat model of SMAO shock.Following MLR,mean arterial blood pressure was significantly decreased (P < 0.05),contents of MDA and NO as well as activities of NOS and MPO were significantly increased (P < 0.05),but activities of Ca2+-ATPase,Mg2+-ATPase and Ca2+-Mg2+-ATPase as well as ATP content were significantly decreased (P < 0.05).CONCLUSION:MLR aggravates brain injury in a rat model of SMAO shock,which correlates with oxygen-derived free radical injury,NO synthesis and release,sequestration of neutrophilic granulocytes,decreasing activity of cell membrane pumps and energy metabolism dysfunction.Pathogenesis of the intestinal lymphatic pathway should be thoroughly investigated to prevent ischemia/reperfusion injury. | Zigang Zhao Chunyu Niu Aimin Shang Jiaming Tian Rui Han Chunhui Zhang Yuping Zhang Jing Zhang | 2010 | Neural Regeneration Research2010，5，9： | 7 |
| 11 | Preparation and characterization of boron-doped corn straw biochar: Fe(Ⅱ) removal equilibrium and kinetics显示文摘Nowadays,iron ions as a ubiquitous heavy metal pollutant are gradually concerned and the convenient and quick removal of excessive iron ions in groundwater has become a major challenge for the safety of drinking water.In this study,boron-doped biochar(B-BC)was successfully prepared at various preparation conditions with the addition of boric acid.The as-prepared material has a more developed pore structure and a larger specific surface area(up to 897.97 m2/g).A series of characterization results shows that boric acid effectively activates biochar,and boron atoms are successfully doped on biochar.Compared with the ratio of raw materials,the pyrolysis temperature has a greater influence on the amount of boron doping.Based on Langmuir model,the maximum adsorption capacity of 800 B-BC1:2 at25℃,40℃,55℃ are 50.02 mg/g,95.09 mg/g,132.78 mg/g,respectively.Pseudo-second-order kinetic model can better describe the adsorption process,the adsorption process is mainly chemical adsorption.Chemical complexation,ions exchange,and co-precipitation may be the main mechanisms for Fe2+removal. | Long Sui Chunyu Tang Qing Du Ying Zhao Kui Cheng Fan Yang | 2021 | Journal of Environmental Sciences2021，33，8： | 6 |
| 12 | Simulation of Hydrodynamic Performance of Drag and Double Reverse Propeller Podded Propulsors显示文摘不稳定的表演在开的水里拖并且加倍反向的推进器 podded propulsors 数字地用计算液体动力学(CFD ) 被模仿方法。一个动人的网孔方法习惯于更写实地模仿 propulsor 工作条件,和戳,转矩,和两 propulsors 的侧面的力量系数被比较并且分析。在不同进展系数与稳定、不稳定的结果的流动地分发一起对 propulsors 的不同部分起作用的力量被比较。而且,侧面的力量的变化和之间的差别上述二个方法主要被分析。两个方法的戳和转矩结果是类似的,这被显示出。 | Chunyu Guo Pengfei Dou Tao Jing Dagang Zhao | 2016 | Journal of Marine Science and Application2016，15，1： | 6 |
| 13 | Amyloid fibril structure of α-synuclein determined by cryo- electron microscopy显示文摘 | Yaowang Li Chunyu Zhao Feng LUO Zhenying Liu Xinrui Gui Zhipu LUO Xiang Zhang Dan Li Cong Liu Xueming Li | 2018 | Cell Research2018，28，9： | 5 |
| 14 | Dissecting human embryonic skeletal stem cell ontogeny by single-cell transcriptomic and functional analyses显示文摘Human skeletal stem cells(SSCs)have been discovered in fetal and adult long bones.However,the spatiotemporal ontogeny of human embryonic SSCs during early skeletogenesis remains elusive.Here we map the transcriptional landscape of human limb buds and embryonic long bones at single-cell resolution to address this fundamental question.We found remarkable heterogeneity within human limb bud mesenchyme and epithelium,and aligned them along the proximal-distal and anterior-posterior axes using known marker genes.Osteo-chondrogenic progenitors first appeared in the core limb bud mesenchyme,which give rise to multiple populations of stem/progenitor cells in embryonic long bones undergoing endochondral ossification.Importantly,a perichondrial embryonic skeletal stem/progenitor cell(eSSPC)subset was identified,which could self-renew and generate the osteochondral lineage cells,but not adipocytes or hematopoietic stroma.eSSPCs are marked by the adhesion molecule CADM1 and highly enriched with FOXP1/2 transcriptional network.Interestingly,neural crest-derived cells with similar phenotypic markers and transcriptional networks were also found in the sagittal suture of human embryonic calvaria.Taken together,this study revealed the cellular heterogeneity and lineage hierarchy during human embryonic skeletogenesis,and identified distinct skeletal stem/progenitor cells that orchestrate endochondral and intramembranous ossification. | Jian He Jing Yan Jianfang Wang Liangyu Zhao Qian Xin Yang Zeng Yuxi Sun Han Zhang Zhijie Bai Zongcheng Li Yanli Ni Yandong Gong Yunqiao Li Han He Zhilei Bian Yu Lan Chunyu Ma Lihong Bian Heng Zhu Bing Liu Rui Yue | 2021 | Cell Research2021，31，7： | 5 |
| 15 | Space-confined growth of monolayer ReSe2 under a graphene layer on Au foils显示文摘Vertical heterostructures based on two-dimensional(2D)materials have attracted widespread interest for their numerous applications in electronic and optoelectronic devices.Herein,we report the direct construct!on of an abnormal graphene/ReSe2 stack on Au foils by a two-step chemical vapor deposition(CVD)strategy.During the second growth stage,mono layer ReSe2 is found to prefere ntially evolve at the irUerface between the first-grown graphene layer and the Au substrate.The unusual stacking behavior is unraveled by in-situ'cutting open'the upper graphene from the defects to expose the lower ReSe2 using scanning tunneling microscopy(STM).From combination of these results with density functional theory calculations,the domain boundaries and edge sites of graphene are proposed to be adsorption sites for Re and Se precursors,further facilitating the growth of ReSe2 at the van der Waals gap of graphene/Au.This work hereby offers an intriguing strategy for obtaining vertical 2D heterostructures featured with an ultra-clean interface and a designed stacking geometry. | Chunyu Xie Shaolong Jiang Xiaolong Zou Yuanwei Sun Liyun Zhao Min Hong Shulin Chen Yahuan Huan Jianping Shi Xiebo Zhou Zhepeng Zhang Pengfei Yang Yuping Shi Porun Liu Qing Zhang Peng Gao Yanfeng Zhang | 2019 | Nano Research2019，12，1： | 4 |
| 16 | Relationship Between Organ Masses and Basal Metabolic Rate (BMR) in Tree Sparrows (Passer montanus)显示文摘BMR(basal metabolic rate),body mass and organ masses of tree sparrows(Passer montanus) were measured to analyze the correlation between organ masses and BMR in tree sparrows,and to evaluate the underlying physiological causes of difference in BMR. Adult tree sparrows were live-trapped by mist net in Qiqihar City,Heilongjiang Province(47 29'N,124 02'E) . The closed circuit respirometer was used to measure the metabolic rate(MR) ,and controlled the ambient temperature by using a water bath(±0.5℃) . Body masses were measured to the nearest 0.01 g before and after BMR measurements with a Sartorius balance(model BT25S) . The mean value was recorded as body mass. Wet and dry masses of several organs were measured,too. BMR was(4.276± 0.385) mL O 2 /(g h) and mean body mass was(18.522±0.110) g. Since not all the variables were normal distributed,a log 10-transformation of those variables was employed to linearize them,prior to analyses. Simple regression analyses indicated that most organ masses showed a significant high correlation with body mass. Both the small intestine and rectum masses were notable exception to that trend. The body-mass-adjusted residual analysis showed that only the kidney wet mass,brain mass,stomach mass,small mass and rectum wet mass correlated with BMR. In addition,correlations between several organ masses and BMR were observed. Because of the inter-correlations of organ masses,a principal component analysis(PCA) was performed to redefine the morphological variability. The first four components whose eigenvalues were greater than 1 could explain 75.2% variance of BMR. The first component,whose proportion reached 30.19%,was affected mainly by stomach mass,small intestine mass and rectum mass. Therefore,the results supported the hypothesis that BMR was controlled by some 'expensive metabolic' organs. | LI Ming YIN Yajie NIE Chunyu QU Lina ZHNAG Guofa LIANG Yantao ZHAO Xiaoju LIU Jinsong | 2011 | Journal of Northeast Agricultural University(English Edition)2011，18，4： | 4 |
| 17 | Classification of Northeast China Cold Vortex Activity Paths in Early Summer Based on K-means Clustering and Their Climate Impact显示文摘The classification of the Northeast China Cold Vortex(NCCV)activity paths is an important way to analyze its characteristics in detail.Based on the daily precipitation data of the northeastern China(NEC)region,and the atmospheric circulation field and temperature field data of ERA-Interim for every six hours,the NCCV processes during the early summer(June)seasons from 1979 to 2018 were objectively identified.Then,the NCCV processes were classified using a machine learning method(k-means)according to the characteristic parameters of the activity path information.The rationality of the classification results was verified from two aspects,as follows:(1)the atmospheric circulation configuration of the NCCV on various paths;and(2)its influences on the climate conditions in the NEC.The obtained results showed that the activity paths of the NCCV could be divided into four types according to such characteristics as the generation origin,movement direction,and movement velocity of the NCCV.These included the generation-eastward movement type in the east of the Mongolia Plateau(eastward movement type or type A);generation-southeast longdistance movement type in the upstream of the Lena River(southeast long-distance movement type or type B);generationeastward less-movement type near Lake Baikal(eastward less-movement type or type C);and the generation-southward less-movement type in eastern Siberia(southward less-movement type or type D).There were obvious differences observed in the atmospheric circulation configuration and the climate impact of the NCCV on the four above-mentioned types of paths,which indicated that the classification results were reasonable. | Yihe FANG Haishan CHEN Yi LIN Chunyu ZHAO Yitong LIN Fang ZHOU | 2021 | Advances in Atmospheric Sciences2021，38，3： | 4 |
| 18 | Self-synchronization theory of dual motor driven vibration system with two-stage vibration isolation frame显示文摘This paper studies self-synchronization and stability of a dual-motor driven vibration system with a two-stage vibration isolation frame. Oscillation amplitude of the material box large enough can be ensured on the vibration system in order to screen materials. Reduction of the dynamic load transmitted to the foundation can also be achieved for the vibration system. A Lagrange equation is used to set up the motion differential equations of the system, and a dimensionless coupled equation of the eccentric rotors is obtained using a method of modified average small parameter. According to the existence condition of zero solution in the dimensionless coupled equation of the eccentric rotors, the precondition for commencing self-synchronization motion is achieved.The stability condition of self-synchronization is obtained based on the Routh-Hurwitz criterion. The theoretical analysis is validated by simulations and experiments. | He LI Dan LIU Lai JIANG Chunyu ZHAO Bangchun WEN | 2015 | Applied Mathematics and Mechanics(English Edition)2015，36，2： | 4 |
| 19 | Study on repairing canine mandibular defect with porous Mg-Sr alloy combined with Mg-Sr alloy membrane显示文摘To discuss the feasibility of the application of porous Mg-Sr alloy combined with Mg-Sr alloy membrane in the repair of mandibular defects in dogs.The second and third mandibular premolars on both sides were extracted from six dogs.The model of mandible buccal fenestration bone defects were prepared after the sockets healed.Twelve bone defects were randomly divided into groups A and B,then Mg-Sr alloy was implanted in bone defects of group A and covered by Mg-Sr alloy membrane while Mg-Sr alloy was implanted in bone defects of group B and covered by mineralized collagen membrane.Bone defects observed on cone beam computed tomographic images and comparing the gray value of the two groups after 4,8 and 12 weeks.After 12 weeks,the healing of bone defects were evaluated by gross observation,X-ray microscopes and histological observation of hard tissue.Bone defects in each group were repaired.At 8 and 12 weeks,the gray value of group A was higher than that of group B(P<0.05).At 12 weeks,the bone volume fraction of group A was higher than that of group B(P<0.05).The newly woven bone in group A is thick and arranged staggered,which was better than that of group B.Porous Mg-Sr alloy combined with Mg-Sr alloy membrane could further promote the repair of mandibular defects,and obtain good osteogenic effect. | Shanning Zhang Xirao Sun Chunyu Kang Man Yang Yuan Zhao Chengyue Wang | 2020 | Regenerative Biomaterials2020，7，3： | 3 |
| 20 | Molecular dynamics simulation for surface melting and self-preservation effect of methane hydrate显示文摘The surface melting process of structure sI methane hydrate is simulated at T = 240, 260, 280, and 300 K using NVT molecular dynamics method. The simulation results show that a quasi-liquid layer will be formed during the melting process. The density distribution, translation, orientation, and dynamic properties of water molecules in the quasi-liquid layer are calculated as a function of the distance normal to the interface, which indicates the performance of quasi-liquid layer exhibits a continuous change from crystal-like to liquid-like. The quasi-liquid layer plays as a resistance of mass transfer restraining the diffusion of water and methane molecules during the melting process. The resistance of quasi-liquid layer will restrain methane molecules diffuse from hydrate phase to gas phase and slow the melting process, which can be considered as a possible mechanism of self-preservation effect. The performance of quasi-liquid layer is more crystal-like when the temperature is lower than the melt- ing-point of water, which will exhibit an obvious self-preservation. The self-preservation will weaken while the temperature is higher than the melting-point of water because of the liquid-like performance of the quasi-liquid layer. | DING LiYing GENG ChunYu ZHAO YueHong HE XianFeng WEN Hao | 2008 | Science China Chemistry2008，51，7： | 3 |
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