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| 1 | Reduction of low-grade manganese oxide ore by biomass roasting显示文摘The reduction process of manganese dioxide in low-grade manganese ore by biomass roasting was investigated.The calcine of manganese oxide ore was further leached by sulphuric acid, the manganese in ore can be converted into manganese sulfate.Effects of the mass ratio of manganese ore to sawdust, roasting temperature and time, leaching temperature and time, leaching agent concentration and liquid-solid ratio were studied.97.71% of manganese recovery can be achieved under the optimal conditions:the mass ratio of manganese ore to sawdust of 5:1, roasting temperature at 500℃ for 40 min, leaching temperature at 60℃ for 40 min, sulphuric acid concentration of 1 mol/L and liquid-solid ratio of 10:1.Other types of low-grade manganese ore like Guilin ore, Nanning ore and Gongcheng ore were tested and the same results were obtained. | Jingjing SONG Guocai ZHU Ping ZHANG Yuna ZHAO | 2010 | Acta Metallurgica Sinica(English Letters)2010，23，3： | 14 |
| 2 | Recovering indium with sulfating roasting from copper-smelting ash显示文摘A technology for recovering indium from Jinchuan copper-smelting ash was developed. Indium in the ash was first enriched to the leaching-slag in leaching process,and then recovered by sulfating roasting. The method included mix-ing the leaching-slag with sulfuric acid,making them into particles,roasting the mixture,and then leaching the calcine with hot water. Above 90% of indium in calcine could be dissolved into the leaching solution. The optimized conditions were determined as follows: the mass ratio of sulfuric acid to leaching slag was 0.1,the roasting time was about 1 to 1.5 h in the temperature range of 200-250°C,and the calcine was leached for 1 h with 5:1 of liquid/solid ratio at 60°C. Over 99% of in-dium in leaching solution was finally enriched by Zn substitution or sulfide precipitation. | ZHU Guocai ZHENG Mingdan FAN Guanglong ZHAO Yuna | 2007 | Rare Metals2007，26，5： | 12 |
| 3 | Structural basis for the impact of phosphorylation on the activation of plant receptor-like kinase BAK1显示文摘 | Liming Yan Yuanyuan Ma Dan Liu Xiaochao Wei Yuna Sun Xiaoyue Chen Huadong Zhao Jingwen Zhou Zhiyong Wang Wenqing Shui Zhiyong Lou | 2012 | Cell Research2012，22，8： | 10 |
| 4 | Lactobacillus reuteri-derived extracellular vesicles maintain intestinal immune homeostasis against lipopolysaccharideinduced inflammatory responses in broilers显示文摘Background:Lactobacillus reuteri strains are widely used as probiotics to prevent and treat inflammatory bowel disease by modulating the host’s immune system.However,the underlying mechanisms by which they communicate with the host have not been clearly understood.Bacterial extracellular vesicles(EVs)have been considered as important mediators of host-pathogen interactions,but their potential role in commensals-host crosstalk has not been widely studied.Here,we investigated the regulatory actions of EVs produced by L.reuteri BBC3,a gut-associated commensal bacterium of Black-Bone chicken,in the development of lipopolysaccharide(LPS)-induced intestinal inflammation in a chicken model using both in vivo and in vitro experiments.Results:L.reuteri BBC3 produced nano-scale membrane vesicles with the size range of 60-250 nm.Biochemical and proteomic analyses showed that L.reuteri BBC3-derived EVs(LrEVs)carried DNA,RNA and several bioactive proteins previously described as mediators of other probiotics’beneficial effects such as glucosyltransferase,serine protease and elongation factor Tu.In vivo broiler experiments showed that administration of LrEVs exerted similar effects as L.reuteri BBC3 in attenuating LPS-induced inflammation by improving growth performance,reducing mortality and decreasing intestinal injury.LrEVs suppressed the LPS-induced expression of pro-inflammatory genes(TNF-α,IL-1β,IL-6,IL-17 and IL-8),and improved the expression of anti-inflammatory genes(IL-10 and TGF-β)in the jejunum.LrEVs could be internalized by chicken macrophages.In vitro pretreatment with LrEVs reduced the gene expression of TNF-α,IL-1βand IL-6 by suppressing the NF-κB activity,and enhanced the gene expression of IL-10 and TGF-βin LPS-activated chicken macrophages.Additionally,LrEVs could inhibit Th1-and Th17-mediated inflammatory responses and enhance the immunoregulatory cells-mediated immunosuppression in splenic lymphocytes of LPS-challenged chickens through the activation of macrophages.Finally,we revealed that the reduced content of both vesicular proteins and nucleic acids attenuated the suppression of LrEVs on LPS-induced inflammatory responses in ex vivo experiments,suggesting that they are essential for the LrEVs-mediated immunoregulation.Conclusions:We revealed that LrEVs participated in maintaining intestinal immune homeostasis against LPSinduced inflammatory responses in a chicken model.Our findings provide mechanistic insight into how commensal and probiotic Lactobacillus species modulate the host’s immune system in pathogens-induced inflammation. | Rujiu Hu Hua Lin Mimi Wang Yuezhen Zhao Haojing Liu Yuna Min Xiaojun Yang Yupeng Gao Mingming Yang | 2021 | Journal of Animal Science and Biotechnology2021，12，3： | 5 |
| 5 | Reduction of Low-grade Manganese Dioxide Ore Pellets by Biomass Wheat Stalk显示文摘An investigation on reducing low-grade manganese dioxide ore pellets was carried out by using wheat stalk as reductant. The main impact factors of reduction percent such as particle size, biomass/ore ratio, heating rate, nitrogen flow rate, temperature and time in reduction process were discussed. The morphology and component of manganese dioxide ore particle at different stages were also analyzed by scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDS). The results show the increase of the reduction temperature and time, biomass/ore ratio, and the decrease of particle size, heating rate and nitrogen flow rate can significantly enhance reduction efficiency. The reduction kinetic of the manganese ore is controlled by three-dimensional mass diffusion of gaseous reductive volatiles passing from the surface to the core of the ore particles. The activation energy E and frequency factor A were calculated to be 24.15 kJ · mol-1 and 166 min-1 , respectively. Biomass pyrolysis volatiles adsorbed onto the surface of the ore particle leads to serious variation of the microstructures and chemical composition of the manganese ore particles. | Honglei ZHANG Guocai ZHU Hong YAN Yuna ZHAO Tiancheng LI Xiujuan FENG | 2013 | Acta Metallurgica Sinica(English Letters)2013，26，2： | 3 |
| 6 | Kinetics of recovering germanium from lignite ash with chlorinating roasting methods显示文摘由使氯化烤恢复 Ge 的一个过程被提出。因为它的低沸腾点, GeCl4 与褐煤灰被分开并且恢复。运动分析显示使氯化烤过程与缩小模型的 unreacted 核心适合,反应率方程对应于 1 吗?2a/3?( 1?一) 2/3 = kt。明显的激活精力 Ea 被计算是在 pH = 的媒介的 22.36 kJ D301R 树脂 3.47。静态地浸透的吸附能力是 410 mg/g。在 D301R 树脂上吸附的磅(IV ) 能是由 1.0-2.0 mol/L NaOH 的 eluted。率常数是 k298 = 5. | ZHU Guocai WANG Jingyan CHENG Zhuo ZHAO Yuna | 2008 | Rare Metals2008，27，3： | 3 |
| 7 | Photonic integrated spiking neuron chip based on a self-pulsating DFB laser with a saturable absorber显示文摘We proposed and experimentally demonstrated a simple and novel photonic spiking neuron based on a distributed feedback(DFB)laser chip with an intracavity saturable absorber(SA).The DFB laser with an intracavity SA(DFBSA)contains a gain region and an SA region.The gain region is designed and fabricated by the asymmetric equivalentπ-phase shift based on the reconstruction-equivalent-chirp technique.Under properly injected current in the gain region and reversely biased voltage in the SA region,periodic self-pulsation was experimentally observed due to the Q-switching effect.The self-pulsation frequency increases with the increase of the bias current and is within the range of several gigahertz.When the bias current is below the self-pulsation threshold,neuronlike spiking responses appear when external optical stimulus pulses are injected.Experimental results show that the spike threshold,temporal integration,and refractory period can all be observed in the fabricated DFB-SA chip.To numerically verify the experimental findings,a time-dependent coupled-wave equation model was developed,which described the physics processes inside the gain and SA regions.The numerical results agree well with the experimental measurements.We further experimentally demonstrated that the weighted sum output can readily be encoded into the self-pulsation frequency of the DFB-SA neuron.We also benchmarked the handwritten digit classification task with a simple single-layer fully connected neural network.By using the experimentally measured dependence of the self-pulsation frequency on the bias current in the gain region as an activation function,we can achieve a recognition accuracy of 92.2%,which bridges the gap between the continuous valued artificial neural networks and spike-based neuromorphic networks.To the best of our knowledge,this is the first experimental demonstration of a photonic integrated spiking neuron based on a DFB-SA,which shows great potential to realizing large-scale multiwavelength photonic spiking neural network chips. | YUECHUN SHI SHUIYING XIANG XINGXING GUO YAHUI ZHANG HONGJI WANG DIANZHUANG ZHENG YUNA ZHANG YANAN HAN YONG ZHAO XIAOJUN ZHU XIANGFEI CHEN XUN LI YUE HAO | 2023 | Photonics Research2023，11，8： | 2 |
| 8 | An investigation on stability of biomass reduced manganese dioxide ore显示文摘In this study,how to improve the stability of reduced manganese oxide ore was discussed by investigating reoxidation conditions and kinetics mechanism in the cooling process of manganese dioxide ore reduced by biomass.The effects of the temperature and time,chip size of biomass,raw materials thickness and different additives on stability of the products were determined.The valence variation of manganese in ore and the reoxidation kinetics of reduced products were studied.The results show that decrease of reduction temperature and time,and increase of raw materials thickness and little H2SO4 additive are favorable for the stability of the reduced products.The kinetics mechanism of the reoxidation is controlled by diffusion with dynamic apparent activation energy of E1=25.10 kJ·mol-1,and conformation of manganese in the process is changed from MnO to Mn3O4. | Honglei ZHANG Guocai ZHU Hong YAN Yuna ZHAO Fangpu CHEN Wenjuan WANG | 2012 | Acta Metallurgica Sinica(English Letters)2012，25，6： | 2 |
| 9 | FLNa negatively regulated proliferation and metastasis in lung adenocarcinoma A549 cells via suppression of EGFR显示文摘Filamin A (FLNa ) 是无所不在地表示的细胞质的蛋白质,它 24 次象 Ig 一样重复跟随的一个 N 终端肌动朊绑定领域(ABD ) 创作。FLNa 作为连接 transmembrane 受体的细胞骨架蛋白质工作,包括 integrins,到 F 肌动朊并且用作发信号的中介。最近的研究作为与超过 90 蛋白质交往并且在细胞的发信号的 transduction 起重要作用的支架蛋白质识别了 FLNa。在人的 FLNa 基因的变化或缺点被显示了引起众多的发展缺点。而且, FLNa 的异常表示在许多癌症被观察了例如甲状旁腺的肿瘤,颈的癌症,和乳癌。然而,它在肺腺癌的角色很少被讨论了。在现在的学习,我们的在里面 vitro 并且在 vivo,研究证明在肺癌症房间线 A549 房间的那 silencing FLNa 表情由提高表皮的生长因素受体和英皇家空军之阶级最低之兵发信号小径的激活支持了 A549 房间的增长,移植,和侵略。这些结果在肺癌症和揭开的新奇机制使 FLNa 的新奇功能清楚些,这些结果为肺腺癌为预言和治疗提供了可能的目标。 | Yuna Zhang Tienian Zhu Jingpu Liu Jiankun Liu Dongmei Gao Tongyi Su Ruijing Zhao | 2018 | Acta Biochimica et Biophysica Sinica2018，50，2： | 2 |
| 10 | Study in reductive- roast leaching manganese from low-grade manganese dioxide ores using cornstalk as reductant显示文摘 | CHENG Zhuo ZHU Guoeai ZHAO Yuna | 2009 | Hydrometallurgy2009，96，12： | 1 |
| 11 | Preparation and properties of ZnO nano-whiskers显示文摘By a novel controlled combustion synthesis method, a large amount of ZnO nano-whiskers with different morphologies like nanotetrapods, long-leg nanotetrapod and multipods, were prepared without any catalysts and additives in open air at high temperature. Their morphologies, structures and optical properties were in-vestigated by using SEM, XRD and PL spectrum. The possible growth mechanisms on the ZnO nano-whiskers were proposed in this paper. | SHI XiaoLing CAO MaoSheng ZHAO YuNa SONG WeiLi RONG JiLi | 2008 | Science China(Technological Sciences)2008，51，9： | 1 |
| 12 | First principles calcula-tions of electronic,dynamical,and thermodynamic properties of rocksalt ScX(X=N,P,As,Sb)显示文摘 | Xue Wenhui Yu You Zhao Yuna | 2009 | Comput Mater Sci2009，45，： | 1 |
| 13 | A novel and simple combustion route towards long legs nanotetrapod ZnO显示文摘 | Zhao Yuna Cao Maosheng Li Jingang | 2005 | Mater Res Bull2005，40，10： | 1 |
| 14 | Engagement of TLR and Dectin-1/Syk Signaling Is Required for Activation of Notch Targets in Dendritic Cells显示文摘Pattern-recognition receptors,such as toll-like receptors(TLRs),detect a wide range of microbial products and initiate innate immune responses leading to the production of inflammatory mediators.In addition,TLR signaling also activates expression of Notch target genes that play crucial roles in suppression of TLR-triggered inflammatory responses.However,whether TLR signaling pathways engaged by other classes of pattern-recognition receptors induce expression of Notch target genes remains unclear.Here we demonstrate that zymosan,a stimulus for TLR2 and dectin-1,strongly induces expression of multiple Notch target genes in both human and murine dendritic cells.Mechanistically,induction of Notch targets by zymosan is both TLR2-and Syk-dependent through activation of mitogen-activated protein kinases and the transcription factor c-Fos.Hence,our data reveals a novel mechanism that efficient induction of Notch target genes requires engagement of TLR and dectin-1/Syk signaling pathways. | Yuna Zhao Chanyang Ju Karmen Au Jimmy Zhu Baohong Zhao Yingli Shang Xiaoyu Hu | 2021 | Infectious Microbes & Diseases2021，3，2： | 1 |
| 15 | Thermal decomposition kinetics and mechanism of magnesium bicarbonate aqueous solution显示文摘 | Yuna Zhao Guocai Zhu | 2007 | Hydrometallurgy2007，，3： | 1 |
| 16 | With epilepsy as the symptoms start youth eerebrovascular malformation in 15 eases of clin- ical and imaging analysi显示文摘 | Zhao Hui Ding Changqing Zhang Yuna | 2012 | Journal of Qiqihar Medical College2012，21，22： | 1 |
| 17 | Surface modification of electrospun fibers with mechano-growth factor for mitigating the foreign-body reaction显示文摘The implantation of synthetic polymeric scaffolds induced foreign-body reaction(FBR)seriously influence the wound healing and impair functionality recovery.A novel short peptide,mechano-growth factor(MGF),was introduced in this study to modify an electrospun polycaprolactone(PCL)fibrous scaffold to direct the macrophage phenotype transition and mitigate the FBR.In vitro studies discovered the cell signal transduction mechanism of MGF regulates the macrophage polarization via the expression of related genes and proteins.We found that macrophages response the MGF stimuli via endocytosis,then MGF promotes the histone acetylation and upregulates the STAT6 expression to direct an anti-inflammatory phenotype transition.Subsequently,an immunoregulatory electrospun PCL fibrous scaffold was modified by silk fibroin(SF)single-component layer-by-layer assembly,and the SF was decorated with MGF via click chemistry.Macrophages seeded on scaffold to identify the function of MGF modified scaffold in directing macrophage polarization in vitro.Parallelly,rat subcutaneous implantation model and rat tendon adhesion model were performed to detect the immunomodulatory ability of the MGF-modified scaffold in vivo.The results demonstrate that MGF-modified scaffold is beneficial to the transformation of macrophages to M2 phenotype in vitro.More importantly,MGF-functionalized scaffold can inhibit the FBR at the subcutaneous tissue and prevent tissue adhesion. | Yang Song Linhao Li Weikang Zhao Yuna Qian Lili Dong Yunnan Fang Li Yang Yubo Fan | 2021 | Bioactive Materials2021，6，9： | 1 |
| 18 | Study in reduction roast leaching manganese from low - grade manganese dioxide ores using cornstalk as reductant 显示文摘 | Cheng Zhuo Zhu Guocai Zhao Yuna | 2009 | Hydrometallurgy2009，96，2： | 1 |
| 19 | Study in reduction- roast leaching manganese from low-grade manganese dioxide ores using cornstalk as reductant 显示文摘 | Cheng Zhuo Zhu Guoeai Zhao Yuna | 2009 | Hydrometallurgy2009，96，12： | 1 |
| 20 | A theory on constructing blocked two-level designs with general minimum lower order confounding显示文摘仅当试验性的单位是同类的,到试验性的单位的处理联合的完全随机的分配是适当的。当实验的尺寸相对大时,如此的同质不能总是被保证。合适把不同类的单位划分成同类的组,作为块知道,是实际设计策略。怎么划分试验性的单位因为一个给定的图案是一个重要问题。堵住的一般最小降低惊讶的顺序为选择的一个新标准被堵住图案。在加倍的帮助下,理论和秒订浸透的设计,我们在场在堵住的一般最小下面构造最佳的堵住的图案上的一个理论降低顺序惊讶标准。 | Yuna ZHAO Shengli ZHAO Min-Qian LIU | 2016 | Frontiers of Mathematics in China2016，11，1： | 1 |
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