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| 1 | On solutions of matrix equation AXB+CVD=F显示文摘 | Xu G Wei M Zheng D | 1998 | Linear Algebra Appl1998，279，： | 2 |
| 2 | Serotonin type 3 receptor subunit gene polymorphisms associated with psychosomatic symptoms in irritable bowel syndrome:A multicenter retrospective study显示文摘BACKGROUND Single-nucleotide polymorphisms(SNPs)of the serotonin type 3 receptor subunit(HTR3)genes have been associated with psychosomatic symptoms,but it is not clear whether these associations exist in irritable bowel syndrome(IBS).AIM To assess the association of HTR3 polymorphisms with depressive,anxiety,and somatization symptoms in individuals with IBS.METHODS In this retrospective study,623 participants with IBS were recruited from five specialty centers in Germany,Sweden,the United States,the United Kingdom,and Ireland.Depressive,anxiety,and somatization symptoms and sociodemographic characteristics were collected.Four functional SNPs—HTR3A c.-42C>T,HTR3B c.386A>C,HTR3C c.489C>A,and HTR3E c.*76G>A—were genotyped and analyzed using the dominant and recessive models.We also performed separate analyses for sex and IBS subtypes.SNP scores were calculated as the number of minor alleles of the SNPs above.The impact of HTR3C c.489C>A was tested by radioligand-binding and calcium influx assays.RESULTS Depressive and anxiety symptoms significantly worsened with increasing numbers of minor HTR3C c.489C>A alleles in the dominant model(F_(depressive)=7.475,P_(depressive)=0.006;F_(anxiety)=6.535,P_(anxiety)=0.011).A higher SNP score(range 0-6)was linked to a worsened depressive symptoms score(F=7.710,P-linear trend=0.006)in IBS.The potential relevance of the HTR3C SNP was corroborated,showing changes in the expression level of 5-HT3AC variant receptors.CONCLUSION We have provided the first evidence that HTR3C c.489C>A is involved in depressive and anxiety symptoms in individuals with IBS.The SNP score indicated that an increasing number of minor alleles is linked to the worsening of depressive symptoms in IBS. | Sabrina Berens Yuanjun Dong Nikola Fritz Jutta Walstab Mauro D'Amato Tenghao Zheng Verena Wahl Felix Boekstegers Justo Lorenzo Bermejo Cristina Martinez Stefanie Schmitteckert Egbert Clevers Felicitas Engel Annika Gauss Wolfgang Herzog Robin Spiller Miriam Goebel-Stengel Hubert Mönnikes Viola Andresen Frieling Thomas Jutta Keller Christian Pehl Christoph Stein-Thöringer Gerard Clarke Timothy G Dinan Eamonn M Quigley Gregory Sayuk Magnus Simrén Jonas Tesarz Gudrun Rappold Lukas van Oudenhove Rainer Schaefert Beate Niesler | 2022 | World Journal of Gastroenterology2022，28，21： | 2 |
| 3 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017，25，5： | 2 |
| 4 | Cancer Genome Scanning in Plasma: Detection of Tumor-Associated Copy Number Aberrations, Single-Nucleotide Variants, and Tumoral Heterogeneity by Massively Parallel Sequencing显示文摘 | Chan K C Allen Jiang Peiyong Zheng Yama W L Liao Gary J W Sun Hao Wong John Siu Shing Shun N Chan Wing C Chan Stephen L Chan Anthony T C Lai Paul B S Chiu Rossa W K Lo Y M D | 2013 | Clinical Chemistry2013，，1： | 2 |
| 5 | Bactericidal Mode of Titanium Dioxide Photoeatalysis显示文摘 | HUANG Zheng MANESS P C BLAKE D M | 2000 | Journal of Photochemistry and Photobiology Chemistry2000，，130： | 1 |
| 6 | Fluoride Exposure From Burning Coal-clay in Guizhou Province,China显示文摘 | Wu D S Zheng B S Wang A M | 2004 | Fluoride2004，37，1： | 1 |
| 7 | Screening for anti-lipase prop- erties of 37 traditional Chinese medicinal herbs显示文摘 | Zheng C D Duan Y Q Gao J M | 2010 | J Chin Med Assoc2010，73，6： | 1 |
| 8 | Combinatorial synergy induced by adenoviral-mediated MDA-7 and Herceptin in Her-2 + breast cancer cells 显示文摘 | Bocangel D Zheng M Mhashilkar A | 2006 | Cancer Gene Ther2006，13，10： | 1 |
| 9 | H5N1 influenza virus pathogenesis in genetically diverse mice is mediated at the level of viral load显示文摘 | Boon AC Finkelstein D Zheng M | | 0，，05： | 1 |
| 10 | The TIL commissioning and performance显示文摘 | X Zhang W Zheng X Wei F Jing Z Sui K Zheng Q Xu X Yuan X Jiang L Yang P Ma M Li J Wang D Hu S He F Li Z Peng B Feng H Zhou L Guo X Li X Zhang J Su Q Zhu H Yu R Zhao C Ma H He D Fan W Zhang | 2008 | Journal of Physics: Conference Series2008，，3： | 1 |
| 11 | A Simulation of Dynamic Recrystallization by Coupling a Cellular Automaton Method With a Topology Deformation Technique 显示文摘 | Xiao N M Zheng C W Li D Z | 2008 | Computational Materials Science2008，41，3： | 1 |
| 12 | Comparison of particle packing models for proportioning concrete constituents for minimum voids ratio显示文摘 | Jones M R Zheng L Newlands M D | 2002 | Materials and Structures2002，35，2： | 1 |
| 13 | Genetic diversity of Gli-1,Gli-2 and Glu-1 alleles amonkg Chinese endemic wheat显示文摘 | Wei Y M Zheng Y H Liu D C | 2001 | Acta Bot Sin2001，43，8： | 1 |
| 14 | The new Characteristics of Coal-burning Bndemic Fluorosis in Some Areas in North-western Guizhou显示文摘 | Wu D S Zheng B S Wang A M | 2004 | Metal Ions in Biology and Medicine2004，8，： | 1 |
| 15 | Direct catalytic conversion of cellulose into ethylene glycol using nickel-promoted tungsten carbide catalysts显示文摘 | JI N ZHANG T ZHENG M Y WANG A Q WANG H WANG X D CHENG J G | 2008 | Angew Chem2008，120，44： | 1 |
| 16 | Intedeu- kin-24 overcomes temozolomide resistance and enhances cell death by down-regulation of O6-methylguanine-DNA methyltransferase in human melanoma cells 显示文摘 | ZHENG M BOCANGEL D RAMESH R | 2008 | Mol Cancer Ther2008，7，12： | 1 |
| 17 | On Solutions of Matrix Equation AXB+CYD=F 显示文摘 | XU G P WEI M S ZHENG D S | 1998 | Linear Aig Appl1998，279，： | 1 |
| 18 | Segmentation of greenvegetation of crop canopy images based on mean shift andfisher linear discriminant显示文摘 | Zheng L Y Shi D M Zhang J T | 2010 | Pattern Recognition Letters2010，31，： | 1 |
| 19 | Effects of dietary lipid levels on growth, survival and lipid metabolism during early ontogeny of Pelteobagrus vachelli larvae显示文摘 | Zheng K K Zhu X M Han D | 2010 | Aquaculture2010，299，14： | 1 |
| 20 | Quercetin activates AMP- activated protein kinase by reducing PP2C expression protecting old mouse brain against high cholesterol-induced neurotoxicity显示文摘 | Lu J Wu D M Zheng Y L | 2010 | J Pathol2010，222，2： | 1 |
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