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| 1 | 42,573 cases of hepatectomy in China: a multicenter retrospective investigation显示文摘Hepatectomy is currently routinely performed in most hospitals in China. China owns the largest population of liver diseases and the biggest number of liver resection cases. A nationwide multicenter retrospective investigation involving 112 hospitals was performed, and focused on liver resection for patients with hepatocellular carcinoma(HCC). 42,573 cases of hepatectomy were enrolled, and 18,275 valid cases of liver resection for HCC patients were selected for statistical analysis. The epidemiology of HCC, distribution of hepatectomy, postoperative complications and prognosis were finally analyzed. In the 18,275 HCC patients,81% had hepatitis B virus infection and 10% had hepatitis C virus infection. 38% of the HCC patients had normal Alphafetoprotein(AFP) level, and other 35% had an AFP level lower than 400 ng mL^(-1). In the study period, 97% of the hepatectomy for HCC were treated with open surgery, and 23.81% had vascular exclusion techniques. The operation time was(191.7±105.6) min,the blood loss was(546.0±562.8) m L, and blood transfusion was(543.0±1,035.2) m L. The median survival for HCC patients was 631 days, with 1-, 3-, and 5-year overall survival of 73.2%, 28.8% and 19.6%, respectively. Liver cirrhosis, multiple nodules,tumor thrombosis and high AFP level were risk factors that affect postoperative survival. | Binhao Zhang Bixiang Zhang Zhiwei Zhang Zhiyong Huang Yifa Chen Minshan Chen Ping Bie Baogang Peng Liqun Wu Zhiming Wang Bo Li Jia Fan Lunxiu Qin Ping Chen Jingfeng Liu Zhe Tang Jun Niu Xinmin Yin Deyu Li Songqing He Bin Jiang Yilei Mao Weiping Zhou Xiaoping Chen | 2018 | Science China(Life Sciences)2018，61，6： | 39 |
| 2 | Optical property and spectroscopy studies on the selected lubricating oil in the terahertz range显示文摘The optical property and spectroscopy of selected kinds of lubricating oil are studied based on the terahertz time-domain spectroscopy (THz-TDS) in the spectral range of 0.3-1.6 THz. The samples are classified by their characteristics via the near-infrared spectrum. The experimental results reveal that lubricating oil is more sensitive in the range of terahertz than in the near-infrared,and the specific kinds of lubricating oil can be identified according to their different spectral features in the terahertz range. The THz-TDS technology applied to lubricating oil analysis has potentially significant impact on the petroleum field. | TIAN Lu ZHOU QingLi JIN Bin ZHAO Kun ZHAO SongQing SHI YuLei ZHANG CunLin | 2009 | Science China(Physics,Mechanics & Astronomy)2009，52，12： | 25 |
| 3 | Identification of aberrant cell cycle regulation in Epstein-Barr virus-associated nasopharyngeal carcinoma by cDNA microarray and gene set enrichment analysis显示文摘 | Wenling Zhang Zhaoyang Zeng Yanhong Zhou Wei Xiong Songqing Fan Lan Xiao Donghai Huang Zheng Li Dan Li Minghua Wu Xiaoling Li Shourong Shen Rong Wang Li Cao Ke Tang Guiyuan Li | 2009 | Acta Biochimica et Biophysica Sinica2009，41，5： | 11 |
| 4 | Spectrum features of commercial derv fuel oils in the terahertz region显示文摘Characteristic spectra in the 0.5-2.5 terahertz (THz) range of three commercial derv fuel oils have been obtained using THz time-domain spectroscopy and calculated using density functional theory.The simulated results and experimental absorption curves suggest that the skeleton vibration is predominant in the THz region,and the absorption bumps of diesels are a superposition of various components.The investigation demonstrates that different diesels can be distinguished using THz time-domain spectroscopy and THz technology is a promising method to detect the composition and properties of diesels via chemical analysis. | ZHAO Hui ZHAO Kun TIAN Lu ZHAO SongQing ZHOU QingLi SHI YuLei ZHAO DongMei ZHANG CunLin | 2012 | Science China(Physics,Mechanics & Astronomy)2012，55，2： | 8 |
| 5 | Effect of ambient oxygen pressure on structural, optical and electrical properties of SnO_2 thin films显示文摘Polycrystalline SnO2 thin films were deposited on sapphire substrates at 450°C under different ambient oxygen pressures by pulsed laser deposition technique. The effect of ambient oxygen pressure on the structural, optical and electri- cal properties of SnO2 thin films was studied. X-ray diffraction and Hall measurements show that increasing the ambient oxygen pressure can improve crystallization of the films and decrease resistivity of the films. A violet emission peak cen- tered at 409 nm was observed from photoluminescence measurements for SnO2 films under deposition ambient oxygen pressure above 5 Pa, which is related to the improvement of crystalline of the films. | ZHAO Songqing ZHOU Yueliang WANG Shufang ZHAO Kun HAN Peng | 2006 | Rare Metals2006，25，6： | 4 |
| 6 | Extracellular calcium elicits feedforward regulation of the roll-like receptor-triggered innate immune response显示文摘 | Songqing Tang Taoyong Chen Mingjin Yang Lei Wang Zhou Yu Bin Xie Cheng Qian Sheng Xu Nan Li Xuetao Cao Jianli Wang | 2017 | Cellular & Molecular Immunology2017，14，2： | 3 |
| 7 | A Novel Multifunctional α-Amylase from the Thermophilic Fungus Malbranchea cinnamomea : Biochemical Characterization and Three-Dimensional Structure显示文摘 | Peng Han Peng Zhou Songqing Hu Shaoqing Yang Qiaojuan Yan Zhengqiang Jiang | 2013 | Applied Biochemistry and Biotechnology2013，，2： | 1 |
| 8 | Comparison of the performance of conventional, temperature-controlled, and ultrasound-assisted ionic liquid dispersive liquid–liquid microextraction combined with high-performance liquid chromatography in analyzing pyrethroid pesticides in honey samples显示文摘 | Jiaheng Zhang Haixiang Gao Bing Peng Songqing Li Zhiqiang Zhou | 2011 | Journal of Chromatography A2011，，38： | 1 |
| 9 | Long non-coding RNA AFAP1-AS1 accelerates lung cancer cells migration and invasion by interacting with SNIP1 to upregulate c-Myc显示文摘Actin filament associated protein 1 antisense RNA 1(named AFAP1-AS1)is a long non-coding RNA and overexpressed in many cancers.This study aimed to identify the role and mechanism of AFAP1-AS1 in lung cancer.The AFAP1-AS1 expression was firstly assessed in 187 paraffin-embedded lung cancer and 36 normal lung epithelial tissues by in situ hybridization.The migration and invasion abilities of AFAP1-AS1 were investigated in lung cancer cells.To uncover the molecular mechanism about AFAP1-AS1 function in lung cancer,we screened proteins that interact with AFAP1-AS1 by RNA pull down and the mass spectrometry analyses.AFAP1-AS1 was highly expressed in lung cancer clinical tissues and its expression was positively correlated with lung cancer patients'poor prognosis.In vivo experiments confirmed that AFAP1-AS1 could promote lung cancer metastasis.AFAP1-AS1 promoted lung cancer cells migration and invasion through interacting with Smad nuclear interacting protein 1(named SNIP1),which inhibited ubiquitination and degradation of c-Myc protein.Upregulation of c-Myc molecule in turn promoted the expression of ZEB1,ZEB2,and SNAIL gene,which ultimately enhanced epithelial to mesenchymal transition(EMT)and lung cancer metastasis.Understanding the molecular mechanism by which AFAP1-AS1 promotes lung cancer's migration and invasion may provide novel therapeutic targets for lung cancer patients'early diagnosis and therapy. | Yu Zhong Liting Yang Fang Xiong Yi He Yanyan Tang Lei Shi Songqing Fan Zheng Li Shanshan Zhang Zhaojian Gong Can Guo Qianjin Liao Yujuan Zhou Ming Zhou Bo Xiang Xiaoling Li Yong Li Zhaoyang Zeng Guiyuan Li Wei Xiong | 2021 | Signal Transduction and Targeted Therapy2021，6，7： | 1 |
| 10 | Cloud-based smartphone-assisted chemiluminescent assay for rapid screening of electroactive bacteria显示文摘Electroactive bacteria(EAB)can transfer electrons to exocellular solid acceptors and have widespread applications in the fields of pollutant degradation,biosynthesis,and hydrogen generation.Traditional EAB screening methods can precisely measure the bacterial extracellular electron transfer ability,but they suffer from time-consuming and labor-intensive procedures.The chemiluminescence technique is effective for the rapid detection of hemoglobin but has not been applied for EAB screening.Herein,we utilized a chemiluminescent assay to identify EAB through a multiheme c-type cytochrome(c-Cyt)triggered chemiluminescent reaction.The multiheme c-Cyts-triggered chemiluminescence was conveniently determined by taking photographs with commercial smartphones and cloud-based computing.The acquired image signal shows a significant and linear relationship with the bacterial concentration.Measurement results of the chemiluminescence intensity triggered by different bacterial species with the proposed method are strongly associated with those of the microplate reading method(Pearson’s r of 0.9795;P<0.01)and dissimilatory Fe(Ⅲ)reduction method(Pearson’s r of 0.9628;P<0.01).Furthermore,this cloud-based and smartphone-assisted chemiluminescent assay is instrument-free and easy to operate,and results can be obtained within 2 min.The findings demonstrate that the proposed method can effectively detect EAB.Therefore,it will be an alternative approach for EAB screening and can have promising applications in microbiology,environmental science,and bioenergy. | WEN JunLin HE DaiGui LUO SongQing ZHOU ShunGui YUAN Yong | 2023 | Science China(Technological Sciences)2023，66，3： | 1 |
| 11 | USE OF IONIC LIQUID-BASED DISPERSIVE LIQUID–LIQUID MICROEXTRACTION AND HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY TO DETECT FORMALDEHYDE IN AIR, WATER, AND SOIL SAMPLES显示文摘 | Bing Peng Jiaheng Zhang Chenghao Wu Songqing Li Yubo Li Haixiang Gao Runhua Lu Wenfeng Zhou | 2014 | Journal of Liquid Chromatography & Related Technologies2014，，6： | 1 |
| 12 | Modeling and analysis of actively Q-switched Fe:ZnSe laser pumped by a 2.8μm fiber laser显示文摘A theoretical model concerning active Q-switching of an Fe:ZnSe laser pumped by a continuous-wave(CW)2.8μm fiber laser is developed.Calculations are compared with the recently reported experiment results,and good agreement is achieved.Effects of principal parameters,including pump power,output reflectivity,ion concentration and temperature of crystal,on the laser output performance are investigated and analyzed.Numerical results demonstrate that similar to highly efficient CWFe:ZnSe laser,low temperature of the crystal is significant to obtain high peak power Q-switched pulses.The numerical simulation results are useful for optimizing the design of actively Q-switched Fe:ZnSe laser. | LIANG Xiaolin ZHOU Songqing LIU Zhizhuang BAO Bengang | 2023 | Optoelectronics Letters2023，19，9： | 0 |
| 13 | BRD7 plays an anti-inflammatory role during early acute inflammation by inhibiting activation of the NF-кB signaling pathway显示文摘Increasing evidence has shown a strong association between tumor-suppressor genes and inflammation.However,the role of BRD7 as a novel tumor suppressor in inflammation remains unknown.In this study,by observing BRD7 knockout mice for 6–12 months,we discovered that compared with BRD7+/+mice,BRD7^(−/−)mice were more prone to inflammation,such as external inflammation and abdominal abscess.By using mouse embryo fibroblast(MEF)cells from the BRD7 knockout mouse,an in vitro lipopolysaccharide(LPS)-stimulated MEF cell line was established.The mRNA levels of interleukin-6(IL-6),tumor necrosis factor-α(TNF-α),chemokine(C-X-C motif)ligand 1(CXCL-1)and inducible nitric oxide synthase(iNOS)were significantly increased in BRD7^(−/−)MEF cells compared with BRD7+/+MEF cells after LPS stimulation for 1 or 6 h.In addition,the cytoplasm-to-nucleus translocation of nuclear factor kappa-B(NF-κB;p65)and an increased NF-κB reporter activity were observed in BRD7^(−/−)MEF cells at the 1 h time point but not at the 6 h time point.Furthermore,an in vivo dextran sodium sulfate(DSS)-induced acute colitis model was created.As expected,the disease activity index(DAI)value was significantly increased in the BRD7^(−/−)mice after DSS treatment for 1–5 days,which was demonstrated by the presence of a significantly shorter colon,splenomegaly and tissue damage.Moreover,higher expression levels of IL-6,TNF-α,p65,CXCL-1 and iNOS,and an increased level of NF-κB(p65)nuclear translocation were also found in the DSS-treated BRD7^(−/−)mice.These findings suggest that BRD7 has an anti-inflammatory role during early acute inflammation by inhibiting activation of the NF-кB signaling pathway,which provides evidence to aid in understanding the therapeutic effects of BRD7 on inflammatory diseases. | Ran Zhao Yukun Liu Heran Wang Jing Yang Weihong Niu Songqing Fan Wei Xiong Jian Ma Xiaoling Li Joshua B Phillips Ming Tan Yuanzheng Qiu Guiyuan Li Ming Zhou | 2017 | Cellular & Molecular Immunology2017，14，10： | 0 |
| 14 | Reflectivity measurement technology of special high reflective mirrors and uncertainty analysis of measurement results显示文摘In order to meet the reflectivity measurement requirements of any incident angle at different points of the large size special high mirror,a rotating cavity ring-down spectroscopy high reflectivity measurement system was built,in which the rotation function of the resonant cavity was set,and the lifting and parallel travelling mechanism of the measured mirror was added.Furthermore,the uncertainty of the measurement results was analyzed and calculated.The results showed that the reflectivity of a high reflective mirror measured by the system was 99.9795%,the measurement accuracy reached the order of 10-6,and the combined standard uncertainty of reflectivity measurement was 0.0028%.Collectively,these results provide a detection guarantee for the maintenance of the large size special high mirror,and provide ideas and methods for the uncertainty analysis of measurement results of similar equipment parameters. | LIANG Xiaolin ZHOU Songqing LI Xiaowu ZHOU Ling CHEN Huihuang | 2023 | Optoelectronics Letters2023，19，1： | 0 |
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