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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020，28，3： | 516 |
| 2 | Structural basis of AMPK regulation by adenine nucleotides and glycogen显示文摘激活安培的蛋白质 kinase (AMPK ) 为糖尿病,肥胖,和癌症的治疗是一个中央细胞的精力传感器和精力动态平衡,和一个有希望的药目标的管理者。这里我们人的 α 的现在的低分辨率的水晶结构; 1 β 2 γ 1 holo-AMPK 建筑群跳了到它的 allosteric 调节的人安培和肝糖模仿 cyclodextrin,两个在 phosphorylated (4.05 Å) 并且 non-phosphorylated (4.60 Å) 状态。另外,我们解决了 2.95 Å人的 kinase 领域(KD ) 的结构跳了到邻近的 autoinhibitory 领域(帮助) 并且表现了广泛生物化学并且 mutational 研究。一起,这些研究由安培和肝糖说明 allosteric AMPK 调整的内在的机制,其绑定改变在交替的帮助(安培) 和糖类绑定模块(肝糖) 之间的 equilibria 相互作用。 | Xiaodan Li Lili Wang X Edward Zhou Jiyuan Ke Parker W de Waal Xin Gu M H Eileen Tan Dongye Wang Donghai Wu H Eric Xu Karsten Melcher | 2015 | Cell Research2015，25，1： | 8 |
| 3 | Destabilization of strigolactone receptor DWARF14 by binding of ligand and E3-1igase signaling effector DWARF3显示文摘 | Li-Hua Zhao X Edward Zhou Wei Yi Zhongshan Wu Yue Liu Yanyong Kang Li Hou Parker W de Waal Suling Li Yi Jiang Adrian Scaffidi Gavin R Flematti Steven M Smith Vinh Q Lam Patrick R Griffin YonghongWang Jiayang Li Karsten Melcher H Eric Xu | 2015 | Cell Research2015，25，11： | 7 |
| 4 | Mutation analysis of autosomal dominant polycystic kidney disease genes in Han Chinese显示文摘 | Zhang S Mei C Zhang D Dai B Tang B Sun T Zhao H Zhou Y Li L Wu Y Wang W Shen X Song J | 2005 | 第二军医大学学报2005，26，8： | 6 |
| 5 | Establishment and Applications of Epstein-Barr Virus-based Episomal Vectors in Human Embryonic Stem Cells显示文摘 | Ren C Zhao M Yang X Li D Jiang X Wang L Shan W Yang H Zhou L Zhou W Zhang H | 2006 | 中国生物学文摘2006，20，7： | 4 |
| 6 | The structural basis of the dominant negative phenotype of the Gαi1β1Y2 G203A/A326S heterotrimer显示文摘 | Ping LIU Ming-zhu JIA X Edward ZHOU Parker W DE WAAL Bradley M DICKSON Bo LlU Li HOU Yan-ting YIN Ya n-yong KANG Yi SHI Karsten MELCHER H Eric XU Yi JIANG | 2016 | Acta Pharmacologica Sinica2016，37，9： | 3 |
| 7 | The Novel Mechanical Property of Tongue of a Woodpecker显示文摘Biomaterials such as bone,teeth,nacre and silk are known to have superior mechanical properties due to their specificnanocomposite structures.Here we report that the woodpecker’s tongue exhibits a novel strength and flexibility due to its specialcomposite micro/nanostructure.The tongue consists of a flexible cartilage-and-bone skeleton covered with a thin layer tissue ofhigh strength and elasticity.At the interface between the cartilage-and-bone skeleton and the tissue layer,there is a hierarchicalfiber-typed connection.It is this special design of the tongue that makes the woodpeckers efficient in catching the insects insidetrees.The special micro/nanostructures of the woodpecker’s tongue show us a potential method to enhance the interfacialconnection between soft and hard material layers for bio-inspired composite system designs. | P Zhou X Q Kong C W Wu Z Chen | 2009 | Journal of Bionic Engineering2009，6，3： | 3 |
| 8 | Analytical study on possible self-excited oscillation in S-shaped regions of pump-turbines显示文摘 | Zhou J X Karney B W Hu M Xu J C | 2011 | Proceedings of the Institution of Mechanical Engineers2011，，8： | 2 |
| 9 | Assay of serum arylesterase activity by fitting reaction curve with an integrated rate equation显示文摘 | Liao F Liu W L Zhou Q X | 2001 | Clin Chim Acta2001，314，12： | 2 |
| 10 | Principal axis-based correspondence between multiple cameras for people tracking 显示文摘 | W M Hu X Zhou | 2006 | IEEE Trans on Pattern Analysis and Machine Intelligence2006，28，4： | 1 |
| 11 | Fiber-reinforced Silicon-containing Arylacetylene Resin Composites显示文摘 | Zhang J Huang J X Zhou W | 2007 | Express Polymer Letters2007，1，12： | 1 |
| 12 | Expression of VGLUTs contributes to degeneration and acquisition of learning and memory 显示文摘 | Cheng X R Yang Y Zhou W X | 2011 | Neurobiol Learn Mem2011，95，： | 1 |
| 13 | CD127 expession inversely corre- lates with Foxl and suppressive fucation of human CI4 + Treg cells 显示文摘 | Liu W Putnam A L Zhou X Y | 2006 | J Exp Med2006，203，7： | 1 |
| 14 | Effect of temperature and strain rate on mechanical properties of 63Sn/37Pb solder alloy显示文摘 | Shi X Q Zhou W Pang H L J | 1999 | ASME:Journal of Electronic Packaging1999，121，： | 1 |
| 15 | Growth and Magnetic Properties of MnO2-β Nanowire Microspheres显示文摘 | YANG J B ZHOU X D JAMES W J | 2004 | Appl Phys Lett2004，85，15： | 1 |
| 16 | Investigation on coal pyrolysis in CO2 atmosphere显示文摘 | DUAN L B ZHAO C S ZHOU W QU C R CHEN X P | 2009 | Energy Fuels2009，23，7： | 1 |
| 17 | Multifractal Detrended Cross-correlation Analysis for Two Nonstationary Signals显示文摘 | Zhou W X | 2008 | Physica Review E2008，，2： | 1 |
| 18 | Level and source of 129I of environmental samples in Xi,an region,China显示文摘 | Zhang L Zhou W Hou X | 2011 | Science of The Total Envi-ronment2011，409，19： | 1 |
| 19 | Effect of high magnetic field on intermetallic phase growth in Ni-AI diffusion couples 显示文摘 | REN X CHEN G Q ZHOU W L WU C W ZHANG J S | 2009 | Journal of Alloys and Compounds2009，472，12： | 1 |
| 20 | Impact of interval between neoadjuvant chemoradiotherapy and surgery for rectal cancer on surgical and oncologic outeome显示文摘 | Zeng W G Zhou Z X Liang J W | 2014 | J Surg Oncol2014，110，4： | 1 |
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