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| 1 | A Globally Convergent Polak-Ribiere-Polyak Conjugate Gradient Method with Armijo-Type Line Search显示文摘In this paper, we propose a globally convergent Polak-Ribiere-Polyak (PRP) conjugate gradient method for nonconvex minimization of differentiable functions by employing an Armijo-type line search which is simpler and less demanding than those defined in [4,10]. A favorite property of this method is that we can choose the initial stepsize as the one-dimensional minimizer of a quadratic modelΦ(t):= f(xk)+tgkTdk+(1/2) t2dkTQkdk, where Qk is a positive definite matrix that carries some second order information of the objective function f. So, this line search may make the stepsize tk more easily accepted. Preliminary numerical results show that this method is efficient. | Gaohang Yu Lutai Guan Zengxin Wei | 2006 | Numerical Mathematics A Journal of Chinese Universities(English Series)2006，15，4： | 11 |
| 2 | Changing features of extreme precipitation in the Yangtze River basin during 1961-2002显示文摘The total precipitation of the highest 1 day, 3 day, 5 day and 7 day precipitation amount (R1D, R3D, R5D and R7D) in the Yangtze River basin was analyzed with the help of linear trend analysis and continuous wavelet transform method. The research results indi-cated that: 1) Spatial distribution of R1D is similar in comparison with that of R3D, R5D and R7D. The Jialingjiang and Hanjiang river basins are dominated by decreasing trend, which is significant at >95% confidence level in Jialingjiang River basin and insignificant at >95% con-fidence level in Hanjiang River basin. The southern part of the Yangtze River basin and the western part of the upper Yangtze River basin are dominated by significant increasing trend of R1D extreme precipitation at >95% confidence level. 2) As for the R3D, R5D and R7D, the western part of the upper Yangtze River basin is dominated by significant increasing trend at >95% confidence level. The eastern part of the upper Yangtze River basin is dominated by decreasing trend, but is insignificant at >95% confidence level. The middle and lower Yangtze River basin is dominated by increasing trend, but insignificant at >95% confidence level. 3) The frequency and intensity of extreme precipitation events are intensified over time. Pre-cipitation anomalies indicated that the southeastern part, southern part and southwestern part of the Yangtze River basin are dominated by positive extreme precipitation anomalies be-tween 1993–2002 and 1961–1992. The research results of this text indicate that the occurrence probability of flash flood is higher in the western part of the upper Yangtze River basin and the middle and lower Yangtze River basin, esp. in the southwestern and southeastern parts of the Yangtze River basin. | ZHANG Zengxin ZHANG Qiang JIANG Tong | 2007 | Journal of Geographical Sciences2007，17，1： | 9 |
| 3 | Neuroimage-Based Consciousness Evaluation of Patients with Secondary Doubtful Hydrocephalus Before and After Lumbar Drainage显示文摘Hydrocephalus is often treated with a cerebrospinal fluid shunt(CFS) for excessive amounts of cerebrospinal fluid in the brain.However,it is very difficult to distinguish whether the ventricular enlargement is due to hydrocephalus or other causes,such as brain atrophy after brain damage and surgery.The non-trivial evaluation of the consciousness level,along with a continuous drainage test of the lumbar cistern is thus clinically important before the decision for CFS is made.We studied 32 secondary mild hydrocephalus patients with different consciousness levels,who received T1 and diffusion tensor imaging magnetic resonance scans before and after lumbar cerebrospinal fluid drainage.We applied a novel machine-learning method to find the most discriminative features from the multi-modal neuroimages.Then,we built a regression model to regress the JFK Coma Recovery Scale-Revised(CRS-R) scores to quantify the level of consciousness.The experimental results showed that our method not only approximated the CRS-R scores but also tracked the temporal changes in individual patients.The regression model has high potential for the evaluation of consciousness in clinical practice. | Jiayu Huo Zengxin Qi Sen Chen Qian Wang Xuehai Wu Di Zang Tanikawa Hiromi Jiaxing Tan Lichi Zhang Weijun Tang Dinggang Shen | 2020 | Neuroscience Bulletin2020，36，9： | 7 |
| 4 | Morphology cluster and prediction of growth of human brain pyramidal neurons显示文摘Predicting neuron growth is valuable to understand the morphology of neurons, thus it is helpful in the research of neuron classification. This study sought to propose a new method of predicting the growth of human neurons using 1 907 sets of data in human brain pyramidal neurons obtained from the website of NeuroMorpho.Org. First, we analyzed neurons in a morphology field and used an expectation-maximization algorithm to specify the neurons into six clusters. Second, naive Bayes classifier was used to verify the accuracy of the expectation-maximization algorithm. Experiment results proved that the cluster groups here were efficient and feasible. Finally, a new method to rank the six expectation-maximization algorithm clustered classes was used in predicting the growth of human pyramidal neurons. | Chao Yu Zengxin Han Wencong Zeng Shenquan Liu | 2012 | Neural Regeneration Research2012，7，1： | 2 |
| 5 | The Dynamic Experiment on Treating Acid Mine Drainage with Iron Scrap and Sulfate Reducing Bacteria Using Biomass Materials as Carbon Source显示文摘The study is aimed at the problem of high content of Cr^(6+),Cr^(3+)and SO_(4)^(2-)is high and low pH value in acid mine drainage(AMD).Moreover,treatment of AMD by sulfate reducing bacteria(SRB)requires the addition of carbon source,while the treating effectiveness is not good enough on its own.The sugarcane slag,the corn cob and the sunflower straw were selected as the SRB carbon source cooperating with iron scrap to construct the dynamic columns 1,2 and 3.The mechanism of removing Cr^(6+),Cr^(3+),SO_(4)^(2-)and H+and the regularity of sustained release of carbon source and TFe release was studied in AMD.The removal efficiency of heavy metal ions,the ability of sustained release of carbon source,and the ability of adjusting acid by the three dynamic columns were compared.The result shows that the average removal rates of Cr^(6+),Cr^(3+)and SO_(4)^(2-)in effluent of dynamic column 1,filled by sugarcane slag,iron scrap and SRB,were 96.9%,67.1%and 54.3%.The average release of TFe and chemical oxygen demand(COD)were 4.4 and 287.3 mg/L.Its average pH was 6.98.Compared with the performance of dynamic columns 1,2 and 3,dynamic column 1 performed best in removing Cr^(6+),Cr^(3+)and SO_(4)^(2-)from AMD and controlling the release of COD and TFe,adjusting the pH of the solution.The study is of significance in treatment of AMD by taking for biomass materials as SRB carbon source in cooperation with iron scrap. | Xianjun Wang Junzhen Di Yanrong Dong Yu Yang Bing Liang Fankang Meng Tingting Wang Wenbo An Zengxin Li Jianzhi Guo | 2021 | Journal of Renewable Materials2021，9，1： | 2 |
| 6 | HIF-1α在乳腺癌及癌前病变中的表达及其与临床病理因素的关系(英文)显示文摘Objective: The aim of this study was to observe the expressions and clinical significance of HIF-1α in breast cancer and precancerous lesions, and analyze the relationship between the expressions and clinicopathological features in breast cancer. Methods: We analyzed the HIF-1α expression in 128 cases of invasive ductal carcinomas, 146 precancerous lesions patients including 89 cases of ductal carcinoma in situ and 57 cases of atypical ductal hyperplasia. 53 cases of usual ductal hyperplasia breast tissues were selected as a control group. The specimens were evaluated for HIF-1α, estrogen receptor(ER) & progesterone receptor(PR), epidermal growth factor receptor type 2(HER2/neu) and Ki-67. Immunoreactivity was semi-quantitatively evaluated in at least 1000 cells examined under the microscope at 40 × magnification and recorded as the percentage of positive tumor cells over the total number of cells examined in the same area. The percentage scores were subsequently categorized. The express of HIF-1α and their relationship with multiple biological parameters including ER & PR, HER2/neu and Ki-67, the biomarkers levels of CA153, CA125 TSGF, and CEA in blood serum and nipple discharge, histological grade, region lymph node metastasis, distant metastasis and recurrence on files were also assessed. Results: Compared with usual ductal hyperplasia, the positive expression rate of HIF-1α in atypical ductal hyperplasia, ductal carcinoma in situ and invasive ductal carcinomas group was significantly increased(P < 0.01). The positive rates of HIF-1α in invasive ductal carcinomas were 68.75%, which were significantly higher than that in ductal carcinoma in situ(43.8%), atypical ductal hyperplasia(31.6%), usual ductal hyperplasia(9.4%; χ2 = 13.44, 22.27, 52.79, respectively, P < 0.01). Statistical analysis showed that difference of abnormal expression rate of HIF-1α between ductal carcinoma in situ and usual ductal hyperplasia(χ2 = 18.37, P = 0. 00), atypical ductal hyperplasia and usual ductal hyperplasia(χ2 = 8.14, P = 0.00) was significant(P = 0.00). However, no significant difference in the positive expression rate of HIF-1α was found between atypical ductal hyperplasia and ductal carcinoma in situ tissue(χ2 = 2.19, P = 0.14). There was a significantly difference in the mean HIF-1α frequency between ER & PR positive invasive ductal carcinomas group and negative group, epidermal growth factor receptor type 2(HER2/neu) positive and negative groups, Ki-67 proliferation index ≤ 14% and > 14% groups, histological grade(I + II) and grade III invasive ductal carcinomas groups, with lymph node metastasis, distant metastasis and recurrence groups(P < 0.05) and without groups(P < 0.05). However, there was not difference in the mean HIF-1α between age(≤ 50 years vs > 50 years), tumor diameter(≤ 2 cm vs > 2 cm; P > 0.05). The nipple discharge and serum levels of CA153, TSGF, CA125 and CEA in invasive ductal carcinomas HIF-1α positive patients were significantly higher than those in the negative patients(P < 0.05). Conclusion: In breast cancer, HIF-1α expression was abnormally increased. The aberration of HIF-1α may play a key role during oncogenesis(atypical ductal hyperplasia or ductal carcinoma in situ) and promote breast cellular transformation into malignancy, a finding useful for further understanding of tumorigenesis. The abnormal expression of HIF-1α may be as an early event in the development of breast tumor. The over-expression of HIF-1α might be important biological markers for invasion, metastasis and recurrence of breast cancer. | Yun'ai Liang Zengxin Li Gangping Wang | 2014 | The Chinese-German Journal of Clinical Oncology2014，13，1： | 2 |
| 7 | Chitosan and oligochitosan enhance the resistance of peach fruit to brown rot显示文摘 | Zengxin Ma Lingyu Yang Haixia Yan John F. Kennedy Xianghong Meng | 2013 | Carbohydrate Polymers2013，，1： | 2 |
| 8 | A nonmono-tone trust region method for unconstrained optimization显示文摘 | Mo Jiangtao Zhang Kecun Wei Zengxin | 2005 | Applied Mathematics and Computation2005，171，： | 1 |
| 9 | Spatial and temporal variability of precipitation maxima during 1960-2005 in the Yangtze River basin and possible associ- ation with large~scale circulation显示文摘 | Qiang Zhang Chong-Yu Xu Zengxin Zhang | 2008 | Journal of Hydrolo- gy2008，353，： | 1 |
| 10 | Atmospheric moisture budget and floods in the Yangtze River basin, China显示文摘 | Zengxin Zhang Qiang Zhang Chongyu Xu Chunling Liu Tong Jiang | 2009 | Theoretical and Applied Climatology2009，，3： | 1 |
| 11 | The convergence properties of some new conjugate gradient methods 显示文摘 | Wei Zengxin Yao Shengwei Liu Liying | 2006 | Applied Mathematics and Computation2006，183，2： | 1 |
| 12 | Discovery of Blake episode in the Xujiayao paleolithic site, Shanxi, China显示文摘 | Liu Chun Su Pu Jin Zengxin | 1992 | Scientia Geologica Sinica1992，1，1： | 1 |
| 13 | The proof of the sufficient descent condition of the Wei-Yao-Liu conjugate gradient method under the strong Wolfe-Powell line search 显示文摘 | Huang Hai Wei Zengxin Yao Shengwei | 2007 | Applied Mathematics and Computation2007，189，2： | 1 |
| 14 | Observed changes of drought/wetness episodes in the Pearl River basin, China, using the standardized precipitation index and aridity index显示文摘 | Qiang Zhang Chong-Yu Xu Zengxin Zhang | 2009 | Theoretical and Applied Climatology (-)2009，，1： | 1 |
| 15 | Precipitation variability (1956–2002) in the Dongjiang River (Zhujiang River basin, China) and associated large-scale circulation显示文摘 | Yongqin David Chen Qiang Zhang Xixi Lu Shurong Zhang Zengxin Zhang | 2010 | Quaternary International2010，，2： | 1 |
| 16 | Regional frequency analysis and spatio-temporal pattern characterization of rainfall extremes in the Pearl River Basin, China显示文摘 | Tao Yang Quanxi Shao Zhen-Chun Hao Xi Chen Zengxin Zhang Chong-Yu Xu Limin Sun | 2009 | Journal of Hydrology2009，，3： | 1 |
| 17 | Observed changes of drought/wetness episodes in the Pearl River basin, China, using the standardized precipitation index and aridity index 显示文摘 | Zhang Qiang Xu Chongyu Zhang Zengxin | 2009 | Theoretical and Applied Climatol- ogy2009，98，12： | 1 |
| 18 | Metallurgy at the Crossroads: New Analyses of Copper-based Objects at Tianshanbeilu, Eastern Xinjiang, China显示文摘Tianshanbeilu is the largest Bronze Age site in eastern Xinjiang, China. Stretching across the entire second millennium BC, it performed a prominent role in connecting the Hexi corridor, Central China and the steppe. A further insight into the metallurgical tradition and the metal supply network is of vital importance to improve our understanding of its multi-connected nature. This paper offers a new set of chemical and isotopic data on the copper-based objects at Tianshanbeilu, including alloying elements, trace elements(impurities) and lead isotopes. Combining the concentrations of arsenic and antimony reveals that arsenic was introduced to copper partially due to the use of specific minerals tethrahedrite-tennantite. Lead isotopes demonstrate that multiple sources of copper were employed at Tianshanbeilu and a majority of them are characterized by common lead, which appears rather different from those of the Central Plains and the Hexi corridor, but highly consistent with local ores. Surprisingly, one object at Tianshanbeilu contains the well-known highly radiogenic lead. This object undoubtedly marks the westernmost boundary of the distribution of the highly radiogenic lead. We also anticipate that more lead isotopic analyses in NW China will further contribute to the study of the highly radiogenic lead in Central China. | LIU Cheng LIU Ruiliang ZHOU Pengcheng LU Chun YANG Zengxin A.Mark POLLARD Peter HOMMEL MA Jian CUI Jianfeng Peter BRAY TONG Jianyi Jessica RAWSON | 2020 | Acta Geologica Sinica(English Edition)2020，94，3： | 1 |
| 19 | Evaluating the non-stationary relationship between precipitation and streamflow in nine major basins of China during the past 50 years 显示文摘 | ZHANG Zengxin CHEN Xi XU Chongyu | 2011 | Journal of Hydrology2011，409，12： | 1 |
| 20 | Examining the influence of river-lake interaction on the drought and water resources in the Poyang Lake basin显示文摘 | Zhang Zengxin Chen Xi Xu Chongyu | 2015 | Journal of Hydrology2015，522，： | 1 |
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