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| 1 | 2019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。 | 刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W | 2020 | 中华高血压杂志2020,28,3: | 516 |
| 2 | Effect of metabolic structures and energy requirements on curdlan production by Alcaligenes faecalis显示文摘 | Zheng, ZY Lee, AW Zhan, XB Shi, Z Wang, L Zhu, L Wu, JR Lin, CC | 2007 | 中国生物学文摘2007,21,10: | 13 |
| 3 | Pulmonary infection control window in treatment of severe respiratory failure of chronic obstructive pulmonary diseases: a prospective, randomized controlled, multi-centred study显示文摘Background Early withdraw from invasive mechanical ventilation (MV) followed by noninvasive MV is a new strategy for changing modes of treatment. This study was conducted to estimate the feasibility and the efficacy of early extubation and sequential noninvasive MV commenced at beginning of pulmonary infection control window in patients with exacerbated hypercapnic respiratory failure caused by chronic obstructive pulmonary diseases (COPD). Methods A prospective, randomized controlled study was conducted in eleven teaching hospitals' respiratory or medical intensive care units in China. Ninety intubated COPD patients with severe hypercapnic respiratory failure triggered by pulmonary infection (pneumonia or purulent bronchitis) were involved in the study. When the pulmonary infection had been controlled by antibiotics and comprehensive therapy, the 'pulmonary infection control window (PIC window)' has been reached. Each case was randomly assigned to study group (extubation and noninvasive MV via facial mask immediately) or control group (invasive MV was received continuously after PIC window by using conventional weaning technique).Results Study group (n=47) and control group (n=43) had similar clinical characteristics initially and at the time of PIC window. Compared with control group, study group had shorter duration of invasive MV [(6.4±4.4) days vs (11.3±6.2) days, P=0.000], lower rate of ventilator associated pneumonia (VAP) (3/47 vs 12/43, P=0.014), fewer days in ICU [(12±8) days vs (16±11) days, P=0.047] and lower hospital mortality (1/47 vs 7/43, P=0.025).Conclusions In COPD patients requiring intubation and invasive MV for hypercapnic respiratory failure, which is exacerbated by pulmonary infection, early extubation followed by noninvasive MV initiated at the start of PIC window may decrease significantly the duration of invasive MV, the risk of VAP and hospital mortality. | Wang, C Zhan, QY Cao, ZX Wei, LQ Cheng, ZZ Liu, S Zhang, JL Chen, RC Luo, Q Niu, SF Zhu, L Wu, DW Fang, BM Wu, TH Wang, CZ Liu, YN | 2005 | Chinese Medical Journal2005,,19: | 6 |
| 4 | Clinical and angiographic characteristics of premenopausal women with coronary artery disease显示文摘当中年的 men.It 的疾病广泛地被接受,背景冠的动脉疾病( CAD )通常被考虑因为荷尔蒙 protection.Based ,为绝经前的女人的 CAD 的风险是低的,没有足够的 concern.Even nowthere ,更绝经前的女人受不了咽峡炎和心肌的梗塞,这仍然是有限的详细数据为了描述绝经前的 CAD patients.This 的 characteristicsmechanism 和预后,文章瞄准了到分析临床所有 P < 0.05 )我们在绝经前的 CAD 发现了单个容器的更多的经常的参与的 .Although (43.2%对 26.9%P=0 ),并且三倍的容器在绝经后( 56-60 岁) CAD 病人(33.8%对 20.4%P=0 )更严重的损害(90%)在留给主要(2.9%对1.1%, P=0.048 )并且近似左前面的下降动脉(男孩)(28.2%对 16.6%P=0 )在绝经前的 CAD ,组是有胸不快的绝经前的女人总是被发现把明显的 atherosclerosismore 使倾向了被定位的 found. | DOU Ke-fei XU Bo YANG Yue-jin Lü Rong QIU Hong YANG Wei-xian MU Zhao-wei GAO Run-lin GAO Zhan CHEN Ji-lin QIAO Shu-bin LI Jian-jun QIN Xue-wen LIU Hai-bo WU Yong-jian CHEN Jue YAO Min YOU Shi-jie YUAN Jin-qing DAI Jun | 2008 | Chinese Medical Journal2008,,23: | 5 |
| 5 | Behavior modeling and verification of movement authority scenario of Chinese Train Control System using AADL显示文摘Train control systems like most digital controllers are, by definition, hybrid systems as they interact with or try to control some aspects of the physical world. Detailed behavior modeling with constraints specification and formal verification, required for reliability prediction, is a great challenge for hybrid system designers.Train control systems further intensify this challenge with extensive interaction between computing units and their physical environment and their mutual dependence on each other. In this paper, we investigate behavior modeling and formal verification of Chinese Train Control System Level 3(CTCS-3) using Architectural Analysis & Design Language(AADL) to cope with this challenge. AADL is an architecture description language for embedded systems and is based on model-based engineering paradigm. Along with structural modeling of embedded systems using the core language constructs, AADL also provides support for language extension through annex sublanguages. In system requirements specification document, the behavior of the CTCS-3 is specified as a set of basic operation scenarios that cooperate with each other to achieve safe and secure functionality of trains.Movement Authority(MA) scenario, explored in this paper, is considered as a basic and most crucial scenario to prevent trains from colliding with each other. The detailed discrete behavior of control system is modeled and verified using the Behavior Language for Embedded Systems with Software(BLESS) annex sublanguage of AADL, and the continuous behavior of train with the cyber–physical interaction(communication between train and control system) is modeled using the Hybrid annex sublanguage. The behavior of the MA scenario at system level is verified using the Hybrid Hoare Logic theorem prover. Behavior constraints are specified as assertions using first-order logic formulas augmented with a simple temporal operator. | AHMAD Ehsan DONG YunWei LARSON Brian Lü JiDong TANG Tao ZHAN NaiJun | 2015 | Science China(Information Sciences)2015,58,11: | 4 |
| 6 | Polar interaction of polymer host-solvent enables stable solid electrolyte interphase in composite lithium metal anodes显示文摘The lithium(Li) metal anode is an integral component in an emerging high-energy-density rechargeable battery.A composite Li anode with a three-dimensional(3 D) host exhibits unique advantages in suppressing Li dendrites and maintaining dimensional stability.However,the fundamental understanding and regulation of solid electrolyte interphase(SEI),which directly dictates the behavior of Li plating/stripping,are rarely researched in composite Li metal anodes.Herein,the interaction between a polar polymer host and solvent molecules was proposed as an emerging but effective strategy to enable a stable SEI and a uniform Li deposition in a working battery.Fluoroethylene carbonate molecules in electrolytes are enriched in the vicinity of a polar polyacrylonitrile(PAN) host due to a strong dipole-dipole interaction,resulting in a LiF-rich SEI on Li metal to improve the uniformity of Li deposition.A composite Li anode with a PAN host delivers 145 cycles compared with 90 cycles when a non-polar host is employed.Moreover,60 cycles are demonstrated in a 1:0 Ah pouch cell without external pressure.This work provides a fresh guidance for designing practical composite Li anodes by unraveling the vital role of the synergy between a 3 D host and solvent molecules for regulating a robust SEI. | Peng Shi Ze-Yu Liu Xue-Qiang Zhang Xiang Chen Nan Yao Jin Xie Cheng-Bin Jin Ying-Xin Zhan Gang Ye Jia-Qi Huang Stephens IfanE L Titirici Maria-Magdalena Qiang Zhang | 2022 | Journal of Energy Chemistry2022,31,1: | 3 |
| 7 | Microsatellite markers derived from bay scallop (Argopecten irradians) expressed sequence tags显示文摘 | Zhan A B Bao Z M Wang X L etal | 2005 | Fisheries Science2005,71,6: | 1 |
| 8 | Genotoxicity of microcystin-LR in human lymphoblastoid TK6 ceils 显示文摘 | Zhan L Sakamoto H Sakuraba M | 2004 | Mutation Research2004,,: | 1 |
| 9 | Fluid geoanalysis in the Chinese Continental Scientific Drilling Project 显示文摘 | Luo L Q Zhan X C Sun Q | 2004 | Geostandards and C eoanalytical Research2004,28,2: | 1 |
| 10 | The heavy ion cooler-storage-ring project (HIRFL- CSR) at Lanzhou显示文摘 | XIA J W ZHAN W L WEN B W | 2002 | Nucl Instrum Methods Phys Res A2002,488,12: | 1 |
| 11 | Simulation for guideroll in 3D-FE analysis of cold ring rolling 显示文摘 | GUO L G YANG H ZHAN M LI H LI L Y | 2004 | Mater Sci Forum2004,,: | 1 |
| 12 | A panel of polymorphic EST-derived microsatellite loci for the bay scallop ( Argopecten irradians ) 显示文摘 | Zhan A B Hu J J Wang X L etal | 2006 | J Mollus Stud2006,72,: | 1 |
| 13 | Indenpendent associations of serum concentrations of 25-hydroxy vitamin D显示文摘 | Zhan G Focr Es L C | 2010 | J Hypertens2010,28,9: | 1 |
| 14 | Estimation of Survival Proba- Bility for a Ship in Beam Seas using the Safe Basin显示文摘 | Zhan J L Seung K L Joon Y K | 2010 | Ocean Engng2010,,37: | 1 |
| 15 | Continuous adminis- tration of recombinant human endostatin (Endostar) : a pre -clini- cal safety study显示文摘 | HUANG R F ZHAN Q ZHOU X L | 2012 | Exp Ther Med2012,3,6: | 1 |
| 16 | Disruption of renal tubular mitochondrial quality control by myo-inositol oxygenase in diabetic kidney disease显示文摘 | Zhan M Usman IM Sun L Kanwar YS | 2014 | Journal of the American Society of Nephrology:JASN2014,,: | 1 |
| 17 | Single-wall carbon nanotubes as attractive toughening agents in alumina based nanoeomposites显示文摘 | ZHAN G D KUNTZ J D WAN J L | 2003 | Nature Materials2003,2,1: | 1 |
| 18 | Performance of an unsaturated expansive soil slope subjected to artificial rainfall infiltration显示文摘 | NGCW W ZHAN L T BAO C G etal | 2003 | Geotechnique2003,53,2: | 1 |
| 19 | Robust disturbance attenuation with stability for linear systems with norm-bounded nonlinear uncertainties显示文摘 | Wang L Y Zhan W | 1996 | IEEE Transactions on Automatic Control1996,41,6: | 1 |
| 20 | Resveratrol enhances GLUT-4 translocation to the caveolar lipid raft fractions through AMPK/Akt/eNOS signalling pathway in diabetic myocardium显示文摘 | Penumathsa SV Thirunavukkarasu M Zhan L | 2008 | J Cell Mol Med2008,12,6: | 1 |