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| 1 | Effects of land use patterns on soil aggregate stability in Sichuan Basin,China显示文摘Soil aggregate stability as a key indicator of soil structure,is a product of interactions between soil environment,management practices,and land use patterns.The objective of this study was to analyze the impact of various land use patterns on soil aggregate stability in Sichuan Basin of southwestern China.The dry-and water-stable aggregate size distributions were determined by manual dry sieving procedure and Yoder's wet sieving procedure,respectively,while microaggregates and its mechanical and chemical stabilities by Kachisky's method,oscillator method,and citrate-dithionate(C-D) reagent method,separately.The results indicated that fractal dimension and surface fractal dimension were useful indicators to reflect soil aggregate distribution.Land use patterns have an obvious influence on soil aggregate stability.In the study area,water stability,mechanical stability,and chemical stability followed the sequence,Barren land > forestland > orchard > cropland,and the original stability and collapse velocity were sensitive to soil properties and soil structure.The difference of aggregate stability under different land use patterns is mainly due to the intensity of human disturbance and cultivation.Improper land use patterns will lead to breakdown of unstable aggregates,producing finer and more-easily transportable particles and microaggregates.In the future,inappropriate cultivation and land use patterns should be changed to protect soil structure,to improve soil aggregate stability and soil fertility in Sichuan Basin. | Zhen Zhang Chaofu Wei Deti Xie Ming Gao Xibai Zeng | 2008 | Particuology2008，6，3： | 9 |
| 2 | Pathological changes in the lungs and lymphatic organs of 12 COVID-19 autopsy cases显示文摘Systematic autopsy and comprehensive pathological analyses of COVID-19 decedents should provide insights into the disease characteristics and facilitate the development of novel therapeutics.In this study,we report the autopsy findings from the lungs and lymphatic organs of 12 COVID-19 decedents—findings that evaluated histopathological changes;immune cell signature and inflammatory factor expression in the lungs,spleen and lymph nodes.Here we show that the major pulmonary alterations included diffuse alveolar damage,interstitial fibrosis and exudative inflammation featured with extensive serous and fibrin exudates,macrophage infiltration and abundant production of inflammatory factors(IL-6,IP-10,TNFo?and IL-I f).The spleen and hilar lymph nodes contained lesions with tissue structure disruption and immune cell dysregulation,including lymphopenia and macrophage accumulation.These findings provide pathological evidence that links injuries of the lungs and lymphatic organs with the fatal systematic respiratory and immune malfunction in critically ill COVID-19 patients. | Qian Liu Yu Shi Jun Cai Yaqi Duan Rongshuai Wang Hongyan Zhang Qiurong Ruan Jiansha Li Lei Zhao Yifang Ping Rong Chen Liang Ren Xiaochun Fei Heng Zhang Rui Tang Xi Wang Tao Luo Xindong Liu Xuequan Huang Zhenhua Liu Qilin Ao Yong Ren Jing Xiong Zhicheng He Haibo Wu Wenjuan Fu Pengnan Zhao Xinwei Chen Guoqiang Qu Yunyun Wang Xi Wang Jia Liu Dongfang Xiang Sanpeng Xu Xiaowei Zhou Qingrui Li Jinghong Ma Heng Li Jie Zhang Sizhe Huang Xiaohong Yao Yiwu Zhou Chaofu Wang Dingyu Zhang Guoping Wang Liang Liu Xiu-Wu Bian | 2020 | National Science Review2020，7，12： | 6 |
| 3 | THRESHOLD INFRARED IMAGE SEGMENTA- TION BASED ON IMPROVED GENETIC ALGO- RITHM 显示文摘 | Zhang Chaofu Ma Li - Ni Jing Lu - Na | 2012 | Information Science and Control En- gineering (ICISCE) lET International Confer- ence on2012，12，： | 1 |
| 4 | TURBULENT STRUCTURE AND LOCAL SIMILARITY IN THE TOWER LAYER OVER THE NANJING AREA显示文摘 | XU YUMAO ZHOU CHAOFU LI ZHONGKAI ZHANG WEI | 1997 | Boundary - Layer Meteorology1997，，1： | 1 |
| 5 | Irrigation water requirements of rice using Cropwat model in Northern Benin显示文摘Understanding crop water requirements(CWR)in semi-arid region is essential for better irrigation practices,scheduling and efficient use of water since the water supply through rainfall is limited.This paper estimated the crop reference and actual evapotranspiration(Eto and ETc)respectively and the irrigation water requirement of rice(Oryza sativa L.)in Benin’s sub-basin of Niger River(BSBNR)of west Africa,using CROPWAT model.The long recorded climatic data,crop and soil data from 1942 to 2012 were computed with the Cropwat model which is based on the United Nations’Food and Agriculture Organization(FAO)paper number 56(FAO56).The Penman-Monteith method was used to estimate ETo.Crop coefficients(Kc)from the phenomenological stages of rice were applied to adjust and estimate the actual evapotranspiration ETc through a water balance of the irrigation water requirements(IR).The results showed the BSBNR annual reference evapotranspiration(ETo)was estimated at 1967 mm.The lowest monthly value of ETo of 123 mm,was observed in August month,middle of the rainy season while the highest value 210 mm was observed in March within dry season.The crop evapotranspiration ETc and the crop irrigation requirements were estimated at 651 mm and 383 mm,respectively in rainy season and 920 mm and 1148 mm,respectively within a dry season.Irrigation projects of these seasons can then be scheduled for water use efficiency based on these findings. | Abdel-Kabirou Bouraima Zhang Weihua Wei Chaofu | 2015 | International Journal of Agricultural and Biological Engineering2015，8，2： | 1 |
| 6 | Data-driven engineering framework with AI algorithm of Ginkgo Folium tablets manufacturing显示文摘Smart manufacturing still remains critical challenges for pharmaceutical manufacturing.Here,an original data-driven engineering framework was proposed to tackle the challenges.Firstly,from sporadic indicators to five kinds of systematic quality characteristics,nearly 2,000,000 real-world data points were successively characterized from Ginkgo Folium tablet manufacturing.Then,from simplex to the multivariate system,the digital process capability diagnosis strategy was proposed by multivariate C_(pk)integrated Bootstrap-t.The C_(pk)of Ginkgo Folium extracts,granules,and tablets were discovered,which was 0.59,0.42,and 0.78,respectively,indicating a relatively weak process capability,especially in granulating.Furthermore,the quality traceability was discovered from unit to end-to-end analysis,which decreased from 2.17 to 1.73.This further proved that attention should be paid to granulating to improve the quality characteristic.In conclusion,this paper provided a data-driven engineering strategy empowering industrial innovation to face the challenge of smart pharmaceutical manufacturing. | Lijuan Ma Jing Zhang Ling Lin Tuanjie Wang Chaofu Ma Xiaomeng Wang Mingshuang Li Yanjiang Qiao Yongxiang Wang Guimin Zhang Zhisheng Wu | 2023 | Acta Pharmaceutica Sinica B2023，13，5： | 1 |
| 7 | TURBULENT STRUCTURE AND LOCAL SIMILARITY IN THE TOWER LAYER OVER THE NANJING AREA显示文摘 | XU YUMAO ZHOU CHAOFU LI ZHONGKAI ZHANG WEI | 1997 | Boundary - Layer Meteorology1997，，1： | 1 |
| 8 | Temporal variation of soil water and its influencing factors in hilly area of Chongqing,China显示文摘The paper studied the temporal variation of soil water content and its influencing factors in hilly area of Chongqing by the yearly data of 2006 and 2007.According to precipitation anomaly percentage,the year 2006 was a dry year and 2007 a normal year.In the dry year 2006,the variations of soil moisture in all three layers(0-10 cm,10-20 cm,20-40 cm)were medium(10%30%),and those of the two deeper layers were weak(CV<10%).Hence,the seasonal variation of soil moisture in the humid area was large in the dry year and small in the wet year.The probability distributions of soil moisture in all three layers in both dry and normal years showed single-peak shapes.However,peak locations and values varied with different layers and years.Among factors affecting the temporal variation of soil moisture in the 0-10 cm layer,during March to May,the meteorological factors including temperature,sunshine and precipitation were all inversely correlated with soil water content variation.The correlations with average temperature and accumulated temperature were both highly significant P<0.01(P=0.00).The inverse correlations with sunshine and precipitation were significant P<0.05(P=0.01).Among soil physical properties,except for bulk density which was inversely correlated with soil moisture,all other properties were positively correlated.Organic material was positively correlated with soil moisture,which suggested that organics had the sponge effect and contributed to soil water storage and movement.During the period of June to September,there was no significant correlation between soil water content and total storage.The meteorological factors of temperature,accumulated temperature and sunshine were all inversely and highly significantly correlated with soil water content P<0.01(P=0.00). | Zhong Shouqin Zhang Weihua Lv Jiake Wei Chaofu | 2014 | International Journal of Agricultural and Biological Engineering2014，7，4： | 1 |
| 9 | Etoposide,dexamethasone,and pegaspargase with sandwiched radiotherapy in early-stage natural killer/T-cell lymphoma:A randomized phase III study显示文摘Methotrexate,etoposide,dexamethasone,and pegaspargase(MESA)with sandwiched radiotherapy is known to be effective for early-stage extranodal natural killer/T-cell lymphoma,nasal type(NKTCL).We explored the efficacy and safety of reduced-intensity,non-intravenous etoposide,dexamethasone,and pegaspargase(ESA)with sandwiched radiotherapy.This multicenter,randomized,phase III trial enrolled patients aged between 14 and 70 years with newly diagnosed early-stage nasal NKTCL from 27 centers in China.Patients were randomly assigned(1:1)to receive ESA(pegaspargase 2,500 IU/m^(2)intramuscularly on day 1,etoposide 200 mg orally,and dexamethasone 40 mg orally on days 2–4)or MESA(methotrexate 1 g/m^(2)intravenously on day 1,etoposide 200 mg orally,and dexamethasone 40 mg orally on days 2–4,and pegaspargase 2,500 IU/m^(2)intramuscularly on day 5)regimen(four cycles),combined with sandwiched radiotherapy. | Huijuan Zhong Shu Cheng Xi Zhang Bing Xu Jiayi Chen Xufeng Jiang Jie Xiong Yu Hu Guohui Cui Juying Wei Wenbin Qian Xiaobing Huang Ming Hou Feng Yan Xin Wang Yongping Song Jianda Hu Yuanhua Liu Xuejun Ma Fei Li Chongyang Wu Junmin Chen Li Yu Ou Bai Jingyan Xu Zunmin Zhu Li Liu Xin Zhou Li Huang Yin Tong Ting Niu Depei Wu Hao Zhang Chaofu Wang Binshen Ouyang Hongmei Yi Qi Song Gang Cai Biao Li Jia Liu Zhifeng Li Rong Xiao Luqun Wang Yujie Jiang Yanyan Liu Xiaoyun Zheng Pengpeng Xu Hengye Huang Li Wang Saijuan Chen Weili Zhao | 2023 | The Innovation2023，4，3： | 0 |
| 10 | TET (Ten-eleven translocation) family proteins: structure, biological functions and applications显示文摘Ten-eleven translocation(TET)family proteins(TETs),specifically,TET1,TET2 and TET3,can modify DNA by oxidizing 5-methylcytosine(5mC)iteratively to yield 5-hydroxymethylcytosine(5hmC),5-formylcytosine(5fC),and 5-carboxycytosine(5caC),and then two of these intermediates(5fC and 5caC)can be excised and return to unmethylated cytosines by thymine-DNA glycosylase(TDG)-mediated base excision repair.Because DNA methylation and demethylation play an important role in numerous biological processes,including zygote formation,embryogenesis,spatial learning and immune homeostasis,the regulation of TETs functions is complicated,and dysregulation of their functions is implicated in many diseases such as myeloid malignancies.In addition,recent studies have demonstrated that TET2 is able to catalyze the hydroxymethylation of RNA to perform post-transcriptional regulation.Notably,catalytic-independent functions of TETs in certain biological contexts have been identified,further highlighting their multifunctional roles.Interestingly,by reactivating the expression of selected target genes,accumulated evidences support the potential therapeutic use of TETs-based DNA methylation editing tools in disorders associated with epigenetic silencing.In this review,we summarize recent key findings in TETs functions,activity regulators at various levels,technological advances in the detection of 5hmC,the main TETs oxidative product,and TETs emerging applications in epigenetic editing.Furthermore,we discuss existing challenges and future directions in this field. | Xinchao Zhang Yue Zhang Chaofu Wang Xu Wang | 2023 | Signal Transduction and Targeted Therapy2023，8，9： | 0 |
| 11 | Restoration technologies of damaged paddy in hilly post-mining and subsidence-stable area of Southwest China显示文摘The paddy fields and water storage facilities are seriously damaged by the coal mine subsiding in the hilly post-mining and subsidence-stable areas in China,which make the farmers there being suffered greatly from the lack of water for traditional rice cultivation and daily life.The purpose of this paper is to find a method to restore the damaged paddy fields,thereby promoting sustainable development of land resources,and alleviating the contradiction between people and land,as well as creating a more inhabitable environment.The research methodology included field experiments,cultivated observation,and field investigation.This paper selected the Songzao Mining Area as the research area,and focused on the restoration technologies of damaged paddy fields,through the following four different measures at three experimental fields:(1)Traditional repeated cattle plowing(CK);(2)Water retention agent with repeated cattle plowing(W&C);(3)Film without holes under tilth depth(FO);and(4)Film with holes under tilth depth(FW).At last,a contrastive analysis of the four measures was made according to the results of the experiments.The results show that the use of water retaining agent with repeated cattle plowing(W&C)can be the most appropriate method to restore the damaged paddy field in the hilly post-mining and subsidence-stable area in southwest China.Compared with the other three measures,its water productivity is the maximum(0.81 kg/m3),and the net income is the highest(1403$/hm^(2)).What’s more,it is simple,short time-consuming,and low cost,which is benefit to generalize the use of this restoration technology. | Zhong Shouqin Wei Chaofu Liu Bo Zhang Weihua Du Jing Zhang Shichao | 2015 | International Journal of Agricultural and Biological Engineering2015，8，2： | 0 |
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