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| 1 | Abundance of antibiotic resistance genes and their association with bacterial communities in activated sludge of wastewater treatment plants: Geographical distribution and network analysis显示文摘Wastewater treatment plants(WWTPs) are deemed reservoirs of antibiotic resistance genes(ARGs). Bacterial phylogeny can shape the resistome in activated sludge. However, the co-occurrence and interaction of ARGs abundance and bacterial communities in different WWTPs located at continental scales are still not comprehensively understood. Here, we applied quantitative PCR and Miseq sequence approaches to unveil the changing profiles of ARGs(sul1, sul2, tet W, tet Q, tet X), int I1 gene, and bacterial communities in 18 geographically distributed WWTPs. The results showed that the average relative abundance of sul1 and sul2 genes were 2.08 × 10^(-1) and 1.32 × 10^(-1) copies/16 S rRNA copies, respectively. The abundance of tet W gene was positively correlated with the Shannon diversity index(H′), while both studied sul genes had significant positive relationship with the int I1 gene. The highest average relative abundances of sul1, sul2, tet X, and int I1 genes were found in south region and oxidation ditch system. Network analysis found that 16 bacterial genera co-occurred with tet W gene. Co-occurrence patterns were revealed distinct community interactions between aerobic/anoxic/aerobic and oxidation ditch systems. The redundancy analysis model plot of the bacterial community composition clearly demonstrated that the sludge samples were significant differences among those from the different geographical areas,and the shifts in bacterial community composition were correlated with ARGs. Together,these findings from the present study will highlight the potential risks of ARGs and bacterial populations carrying these ARGs, and enable the development of suitable technique to control the dissemination of ARGs from WWTPs into aquatic environments. | Haihan Zhang Huiyan He Shengnan Chen Tinglin Huang Kuanyu Lu Zhonghui Zhang Rong Wang Xueyao Zhang Hailong Li | 2019 | Journal of Environmental Sciences2019，31，8： | 9 |
| 2 | Biogeographic distribution patterns of algal community in different urban lakes in China: Insights into the dynamics and co-existence显示文摘Urban lake ecosystems are significant for social development,but currently we know little about the geographical distribution of algal community in urban lakes at a large-scale.In this study,we investigated the algal community structure in different areas of urban lakes in China and evaluated the influence of water quality parameters and geographical location on the algal community.The results showed that obvious differences in water quality and algal communities were observed among urban lakes in different geographical areas.Chlorophyta was the dominant phylum,followed by cyanobacteria in all areas.The network analysis indicated that algal community composition in urban lakes of the western and southern area showed more variations than the eastern and northern areas,respectively.Redundancy analysis and structural equation model revealed that nutrients and p H were dominant environmental factors that affected the algal community,and they showed higher influence than that of iron,manganese and COD Mn concentration.Importantly,algal community and density exhibited longitude and latitude relationship.In general,these results provided an ecological insight into large-scale geographical distributions of algal community in urban lakes,thereby having potential applications for management of the lakes. | Haihan Zhang Rongrong Zong Huiyan He Kaiwen Liu Miaomiao Yan Yutian Miao Ben Ma Xin Huang | 2021 | Journal of Environmental Sciences2021，33，2： | 9 |
| 3 | Identification of novel cis-elements bound by BplMYB46 involved in abiotic stress responses and secondary wall deposition显示文摘Transcription factors(TFs)play vital roles in various biological processes by binding to cis-acting elements to control expressions of their target genes.The MYB TF BplMYB46,from Betula platyphylla,is involved in abiotic stress responses and secondary wall deposition.In the present study,we used a TF-centered yeast onehybrid technology(TF-centered Y1H)to identify the cisacting elements bound by BplMYB46.We screened a shortinsert random library and identified three cis-elements bound by BplMYB46:an E-box(CA(A/T/C)(A/G/C)TG)and two novel motifs,a TC-box(T(G/A)TCG(C/G))and a GT-box(A(G/T)T(A/C)GT(T/G)C).Chromatin immunoprecipitation(ChIP)and effector-reporter coexpression assays in Nicotiana tabacum confirmed binding of BplMYB46 to the TC-box,GT-box,and E-box motifs in the promoters of the phenylalanine ammonia lyase(PAL),peroxidase(POD),and superoxide dismutase(SOD)genes,which function in abiotic stress tolerance and secondary wall biosynthesis.This finding improves our understanding of potential regulatory mechanisms in the response to abiotic stress and secondary wall deposition of BplMYB46 in B.platyphylla. | Huiyan Guo Liuqiang Wang Chuanping Yang Yiming Zhang Chunrui Zhang Chao Wang | 2018 | Journal of Integrative Plant Biology2018，60，10： | 7 |
| 4 | Cow, yak, and camel milk diets differentially modulated the systemic immunity and fecal microbiota of rats显示文摘Cow milk is most widely consumed; however,non-cattle milk has gained increasing interest because of added nutritive values. We compared the health effects of yak,cow,and camel milk in rats. By measuring several plasma immune factors,significantly more interferon-c was detected in the camel than the yak(P = 0.0020) or cow(P = 0.0062) milk group. Significantly more Ig M was detected in the yak milk than the control group(P = 0.0071). The control group had significantly less interleukin 6 than the yak(P = 0.0499)and cow(P = 0.0248) milk groups. The fecal microbiota of the 144 samples comprised mainly of the Firmicutes(76.70 ± 11.03%),Bacteroidetes(15.27 ± 7.79%),Proteobacteria(3.61 ± 4.34%),and Tenericutes(2.61 ± 2.53%) phyla. Multivariate analyses revealed a mild shift in the fecal microbiota along the milk treatment. We further identified the differential microbes across the four groups. At day 14,22 and 28 differential genera and species were identified(P = 0.0000–0.0462),while 8 and 11 differential genera and species(P = 0.0000–0.0013) were found at day 28. Some short-chain fatty acid and succinate producers increased,while certain health-concerned bacteria(Prevotella copri,Phascolarctobacterium faecium,and Bacteroides uniformis) decreased after 14 days of yak or camel milk treatment. We demonstrated that different animal milk could confer distinctive nutritive value to the host. | Yongping Wen Qiuwen He Jia Ding Huiyan Wang Qiangchuan Hou Yi Zheng Changkun Li Yuzhu Ma Heping Zhang Lai-Yu Kwok | 2017 | Science Bulletin2017，62，6： | 4 |
| 5 | Template-free synthesis of carbon doped TiO2 mesoporous microplates for enhanced visible light photodegradation显示文摘钛二氧化物(TiO 2) 广泛地为太阳能变换和环境补习作为稳固的光催化剂被采用。与控制粒子尺寸和缩小的 bandgap 构造多孔的 TiO 2 的能力是为设计的一个必要要求高度有效并且 recyclable 光催化剂。这里,我们报导没有模板的醋酸与高 crystallinity 和 mesoporous 结构为可见光的应答的做碳的 TiO 2 microplates 的合成导致了方法。从醋酸导出的撤退电子的有二齿的羧化物 ligands 能缩小 TiO 2 的 bandgap,这被显示出(1.84 ? eV ) 实质地。而且,结果的 microplate 光催化剂展出优秀 photocatalytic 效率和稳固液体的分离性能,它将为未来是有益的工业应用。 | Juming Liu Lu Han Huiyan Ma Hao Tian Jucai Yang Qiancheng Zhang Benjamin J. Seligmann Shaobin Wang Jian Liu | 2016 | Science Bulletin2016，61，19： | 4 |
| 6 | Nonfatal Child Pedestrian Injury in Two Urban Cities of Guangdong Province,China:Results from a Cross-sectional Survey显示文摘Objective To describe the epidemiological characteristics of nonfatal child pedestrian injuries and provide information to help understand an important public-health problem.Methods This was a school-based,cross-sectional questionnaire survey.The sample (42 750 children) was obtained from two urban cities of Guangdong Province,China,using multi-stage randomized sampling.Information was collected by the respondents self-reporting in the classroom.Results The incidence rate of nonfatal child pedestrian injuries in the cities was 2.0%.Boys had a higher incidence rate (2.6%) than girls (1.4%).Compared to other children,those aged 10 years are at the highest risk.The primary places of occurrence were sidewalks,residential roads,and crosswalks.High-risk behavior of the children immediately prior to injury included mid-block crossings,playing on roads,and crossing on red lights.The major vehicles that caused pedestrian injuries were bicycles,car or vans,and motorcycles.Bruises,fractures,and injuries to the internal organs were the top three types of injuries.Almost 40% of victims were hospitalized,and nearly 30% of the victims suffered long-term disabilities.Conclusion This study shows that nonfatal child pedestrian injuries are a very serious public-health problem in the urban cities of Guangdong.Based on the epidemiological characteristics,prevention strategies and further research should be carried out to reduce the occurrence of injuries. | MA WenJun NIE ShaoPing XU HaoFeng XU YanJun XIE HuiYan ZHANG YuRun | 2011 | Biomedical and Environmental Sciences2011，24，4： | 4 |
| 7 | Genomic insights into the ESBL and MCR-l-producing ST648 Escherichia coli with multi-drug resistance显示文摘多粘菌素由 multidrug 抵抗的克否定的病原体对严重感染充当避难处的一根最终的线。这个常规想法被活动 colistin 抵抗基因(mcr-1 ) 的最近的发现戏剧性地质问在食物动物和世界范围的人是流行的。更重要地, mcr-1 基因被发现与另外的抗菌素抵抗基因 co 局部性,提起可能性与平底锅药抵抗超级臭虫正在出现。然而,很少在 mcr-1-positive 的染色体上被报导细菌的主人水库。这里,我们报导三个人定序的染色体 mcr-1-positive Escherichia coli (E15004, E15015 和 E15017 ) 孤立并且通过细菌的比较 genomics 的分析定义一般特征。和顺序打字的进一步的 genomic 采矿允许我们阐明 MCR-1-carrying E。coli E15017 属于顺序类型 ST648 和 coproduces 扩大光谱的 -lactamase (ESBL ) 。给 ST648 与任何一个新德里 metallo 为伙伴所知的事实 -- lactamase 1 或 ESBL,我们的结果与 multidrug 电阻作为流行克隆加亮 ST648 的可能性。 | Huimin Zhang Christopher H. Seward Zuowei Wu Huiyan Ye Youjun Feng | 2016 | Science Bulletin2016，61，11： | 4 |
| 8 | Quantifying soil erosion with GIS-based RUSLE under different forest management options in Jianchang Forest Farm显示文摘Quantitatively estimating soil erosion with an integration of geographic information system (GIS) and the revised universal soil loss equation (RUSLE) under four different exposed soil proportion scenarios caused by forest management practices was studied at Jianchang Forest Farm. The GIS provided means of input data generation required by RUSLE model and allowed a spatial assessment of the erosion hazard over the study area. Four exposed soil proportion scenarios of 5%, 10%, 20% and 30% were tested with the GIS-based RUSLE model to evaluate soil erosion hazard. The predicted soil erosion potentials were classified into five categories in order to provide valuable aids for management planning. | ZHANG Hengming, WANG Qingli, DAI Limin, Guofan Shao, TANG Una, WANG Shunzhong & GU Huiyan Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang 110016, China Graduate University of Chinese Academy of Sciences, Beijing 100101, China Department of Forestry and Natural Resources, Purdue University, Lafayette IN47901, USA Northeast Forestry University, Harbin 150040, China | 2006 | Science China(Technological Sciences)2006，49，z1： | 3 |
| 9 | Direct observation of interlayer coherent acoustic phonon dynamics in bilayer and few-layer PtSe2显示文摘This work reports the real-time observation of the interlayer lattice vibrations in bilayer and few-layer PtSe_2 by means of the coherent phonon method. The layer-breathing mode and standing wave mode of the interlayer vibrations are found to coexist in such a kind of group-10 transition metal dichalcogenides(TMDCs). The interlayer breathing force constant standing for perpendicular coupling(per effective atom) is derived as 7.5 N/m,2.5 times larger than that of graphene. The interlayer shearing force constant is comparable to the interlayer breathing force constant, which indicates that PtSe2 has nearly isotropic interlayer coupling. The low-frequency Raman spectroscopy elucidates the polarization behavior of the layer-breathing mode that is assigned to have A1 g symmetry. The standing wave mode shows redshift with the increasing number of layers, which successfully determines the out-of-plane sound velocity of PtSe2 experimentally. Our results manifest that the coherent phonon method is a good tool to uncover the interlayer lattice vibrations, beyond the conventional Raman spectroscopy limit. The strong interlayer interaction in group-10 TMDCs reveals their promising potential in high-frequency(~terahertz) micro-mechanical resonators. | XIN CHEN SAIFENG ZHANG LEI WANG YI-FAN HUANG HUIYAN LIU JIAWEI HUANG NINGNING DONG WEIMIN LIU IVAN MKISLYAKOV JEAN MICHEL NUNZI LONG ZHANG JUN WANG | 2019 | Photonics Research2019，7，12： | 3 |
| 10 | Properties and Structures of Bi_2O_3-B_2O_3-TeO_2 Glass显示文摘Glass formation range of Bi2O3—B2O3—TeO2 system has been investigated(B2O3 < 40 mol%).Four glasses with compositions xBi2O3—3OB2O3—(70—x)TeO2(x = 40,50,60 and 70 mol%) have been prepared by using melt quenching technique.The effect of Bi2O3 content on thermal stability,optical properties and structures of these four Bi2O3—B2O3—TeO2 glasses is systematically investigated by inductive coupled plasma emission spectrometer(ICP),differential scanning calorimetry(DSC),Raman spectra and X-ray photoelectron spectroscopy(XPS).It is found that the density,refractive index and optical basicity increase with increasing Bi2O3.The Raman spectra and XPS spectra show that the glass network is mainly constituted by the[BiO6] octahedron,[TeO4]trigonal bipyramidal,[TeO3]trigonal pyramid,[BO3]trigonal pyramid and[BO4]tetrahedron structural units.With increasing Bi2O3,the coordination number around B atom changes from 3 to 4 and [TeO4]units are converted to[TeO3]units.Bi5+ ions may exist in Bi2O3—B2O3—TeO2(BBT) system and their amount grows with increasing Bi2O3 content. | Guoying Zhao Ying Tian Huiyan Fan Junjie Zhang Lili Hu | 2013 | Journal of Materials Science & Technology2013，29，3： | 2 |
| 11 | Research on Steam Oxidation Resistance of Si3N4-bonded SiC Refractories显示文摘The steam oxidation of Si3N4-bonded SiC was determined at 1000℃for 50,100,150,200,250 and 300 h,respectively,according to ASTM C863-2000.The evolution of the phase composition and the microstructure as well as their relationship was investigated by XRD and SEM.The results show that the oxidation rate of Si3N4-bonded SiC is periodic.The presence of nitrogen element can impede the crystallization of SiO2 glass;the local enrichment of CaO impurities is unfavorable for the existence of fibrous SiO2.SiO2 mainly exists as cristobalite when the CaO/SiO2 ratio reaches a suitable level,but gradually transforms to quartz along with the oxidation time when the SiO2 content increases,or the CaO/SiO2 ratio decreases,due to the insufficient mineralization of CaO.The crystallization of SiO2 glass,especially the formation of quartz is the key factor leading to the volume expansion and structural stress.When the cracks extend and reach the surface,the degradation of the material accelerates. | CAO Huiyan HUANG Zhigang ZHANG Xinhua LIU Zhen | 2020 | China's Refractories2020，29，1： | 2 |
| 12 | Pyrolysis of single large biomass particle: Simulation and experiments显示文摘Pyrolysis and heat transfer characteristics of single large biomass particle were investigated using threedimensional unsteady heat transfer model coupled with chemical reactions.The consumption of biomass and the production of products were simulated.Some experiments were designed to provide model parameters for simulation calculations.The simulation was verified by pyrolysis experiments of large biomass particle in a vertical tube furnace.The simulation results show the internal heat and mass transfer law during the pyrolysis of large biomass particle.When the biomass particle diameter is between 10 and 30 mm,for every 5 mm increase in particle diameter,the time required for complete pyrolysis will increase on average by about 50 s.When the pyrolysis temperature is between 673 K and 873 K,a slight decrease in the pyrolysis temperature will cause the time required for the biomass to fully pyrolyze to rise significantly.And the phenomenon is more obvious in the low temperature range.The results indicate that the numerical simulation agrees well with the experimental results. | Kai Wang Huiyan Zhang Sheng Chu Zhenting Zha | 2021 | Chinese Journal of Chemical Engineering2021，34，1： | 2 |
| 13 | Fenton reactions drive nucleotide and ATP syntheses in cancer显示文摘我们在场 14 癌症的织物 transcriptomic 数据的计算研究打字到地址:什么可以驾驶癌症房间分割?我们到由 Fenton 反应的细胞内部的 pH 的那坚持的混乱的分析点可能在癌症开发的根。明确地,我们统计上证明了 Fenton 反应发生在癌症 cytosol,越过所有 14 癌症的线粒体打字,基于经由 Michaelis-Menten 方程综合的癌症组织基因表示数据。另外,我们证明了在疾病房间的 cytosol 的(i) Fenton 反应将连续地房间由产生网质子通过综合的联合使 pH 稳定,对哪个作出回应增加他们的 pH 对哪个 glycolytic ATP 并且由核苷酸综合体消费他们,它可以驱使房间分割连续地综合的核苷酸根除;并且(ii ) 在线粒体的 Fenton 反应与最终来自 H 2 O 2, 大部分从有免疫力的房间发源。一个模型被开发连接这些到癌症开发,在一些变化可以被选择以 Fenton 反应支配的率便于房间分割的地方。 | Huiyan Sun Chi Zhang Sha Cao Tao Sheng Ning Dong Ying Xu | 2018 | Journal of Molecular Cell Biology2018，10，5： | 2 |
| 14 | Comparison of non-catalytic and catalytic fast pyrolysis of corncob in a fluidized bed reactor显示文摘 | Huiyan Zhang Rui Xiao He Huang Gang Xiao | 2008 | Bioresource Technology2008，，3： | 2 |
| 15 | Oxaliplatin,Fluorouracil and Leucovorin (FOLFOX) as First-line Chemotherapy for Metastatic or Recurrent Colorectal Cancer Patients显示文摘OBJECTIVE To investigate the efficiency and safety of the oxaliplatin, fluorouracil(5-FU)and leucovorin regimen(FOLFOX)in previously untreated patients with metastatic or recurrent colorectal cancer. METHODS Previously untreated patients with metastatic or recurrent colorectal cancer received 100 mg/m2 of oxaliplatin intravenously(IV)over 2 h on day 1,and IV 400 mg/m2 of leucovorin over 2 h followed by a bolus of 400 mg/m2 of 5-FU.Then 2,600~3,000 mg/m2 of 5-FU was administered by continuous infusion over 46 h. RESULTS An evaluated response rate was determined for 97 of 105 treated patients.The overal response rate was 35.1%,9 patients(9.3%) had a complete response and 25 patients(25.8%)a partial response.Thirty-two patients(33.0%)developed stable disease and 32.0%of the patients progressed.The median time to progression(TTP)was 7.7 months and the median overal survival 20.5 months.One and 2-year survival rates were 68%and 32%.Toxic effects based on the National Cancer Institute-Common Toxicity Criteria(NCI-CTC),reaching grade 3/4 were:neutropenia 12.3%, anemia 11.3%,vomiting 4.1%and diarrhea 7.2%.Grade 3 neuropathy was 5.1%.The overall survival rate of patients who had received a radical resection was superior to the patients who had not received a operation,or had received a pal iative resection(P=0.0658).The serum levels of CEA,ALP and LDH had no relationship with survival(P>0.05). CONCLUSION The FOLFOX regimen containing oxaliplatin,5-FU plus leucovorin was an efficacious regimen with good tolerability in previously untreated metastatic or recurrent colorectal cancer patients. | Bing Han Ruihua Xu Yanxia Shi Huiyan Luo Xiaojuan Xiang Yuhong Li Li Zhang Tongyu Lin Youjian He | 2007 | Chinese Journal of Clinical Oncology2007，4，6： | 2 |
| 16 | Comparison of catalytic pyrolysis of biomass with MCM-41 and CaO catalysts by using TGA–FTIR analysis显示文摘 | Denghui Wang Rui Xiao Huiyan Zhang Guangying He | 2010 | Journal of Analytical and Applied Pyrolysis2010，，2： | 1 |
| 17 | MicroRNA-25 functions as a potential tumor suppressor in colon cancer by targeting Smad7显示文摘 | Qiang Li Chaoxia Zou Chendan Zou Zhongjing Han Haifeng Xiao Huiyan Wei Wei Wang Lei Zhang Xueying Zhang Qingchao Tang Chunjing Zhang Ji Tao Xishan Wang Xu Gao | 2013 | Cancer Letters2013，，： | 1 |
| 18 | A medical image 3 D recon- struction method based on improved MC and MT algorithms 显示文摘 | Huiyan Jiang Ye Zhang Yudong Zhao | 2009 | Industrial Electronics and Applications2009，，2527： | 1 |
| 19 | Fault prognostics and reliability estimation of DC motor using time series analysis based on degradation data 显示文摘 | Wang Li Zhang Huiyan Xue Hong | 2012 | Journal of Theoretical and Applied Information Technology2012，45，2： | 1 |
| 20 | Relationship between NO_2 Concentration and Meteorological Factors in the Urban Area of Wanzhou District显示文摘Firstly,the daily variations of NO2 concentration in the urban area of Wanzhou in 2012 were analyzed,and then the relationship between NO2 concentration and meteorological factors( precipitation,atmospheric pressure,wind speed,temperature,relative humidity and sunshine hours) was discussed. Finally,the multiple linear regression equation was established to predict NO2 concentration. The results showed that NO2 concentration in the urban area of Wanzhou did not exceed 80 μg /m3in most days from January 1 to December 31 in 2012. Among the six meteorological factors,NO2 concentration correlated significantly with three meteorological factors,that is,NO2 concentration correlated negatively with atmospheric pressure and wind speed but positively with relative humidity. NO2 concentration in the urban area of Wanzhou could be predicted using the multiple linear regression model. According to the rose diagram of wind directions,the wind blowing from the NNW was dominant in the urban area of Wanzhou. | Xiang Yingchun Zhang Liying Mao Xiaozhen Ma Huiyan Qian Ruozhi | 2014 | Meteorological and Environmental Research2014，5，3： | 1 |
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