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| 1 | Identification and analysis of type II TGF-β receptors in BMP-9-induced osteogenic differentiation of C3H10T1/2 mesenchymal stem cells显示文摘我们的以前的研究表明了那根骨头形态基因的蛋白质(BMP-9 ) 9 是最有效的 BMP 之一导致间充质的干细胞(MSC ) 的造骨细胞区别。然而,位于 MSC 的 BMP-9-induced osteogenic 区别下面的分子的机制尚待充分被阐明。在这研究,主导否定(DN ) 类型 II TGF- 受体被构造并且介绍干细胞进 C3H10T1/2,然后,在 vitro 并且在 vivo,试金被执行分析并且识别为 BMP-9-induced 要求的类型 II TGF- 受体成骨。我们发现那三 DN 类型 II TGF-受体, DN-BMPRII , DN-ActRII ,和 DN-ActRIIB ,减少的 BMP-9-induced 碱的磷酸酶(高山)活动,在有约束力的元素( SBE )控制了的 BMP-9-induced Smad 导致了减少记者活动, Smad6 和 Smad7 的减少的 BMP-9-induced 表达式,并且减少在在 vivo 的 vitro 和宫外的骨头形成的 BMP-9-induced 矿化作用,最后导致了减少的骨头群众和不成熟的成骨。这些调查结果强烈建议了那三野类型的 II TGF- 受体, BMPRII, ActRII 和 ActRIIB,可以在 C3H10T1/2 房间的 BMP-9-induced osteogenic 区别起一个功能的作用。然而, C3H10T1/2 干细胞能表示 BMPRII 和 ActRII,然而并非 ActRIIB。用 RNA 干扰(RNAi ) ,我们发现那项酶记者活动和高山活动被 BMP-9 导致了因此被禁止与一起 BMPRII 和 ActRII 击倒。一起拿,我们的结果证明 BMPRII 和 ActRII 是在 C3H10T1/2 房间的 BMP-9-induced osteogenic 区别的功能的类型 II TGF- 受体。 | Ningning Wu Yingze Zhao Yibing Yin Yan Zhang Jinyong Luo | 2010 | Acta Biochimica et Biophysica Sinica2010，42，10： | 20 |
| 2 | Spatial patterns of ephemeral plants in Gurbantünggüt Desert显示文摘In the present research,the authors measured parameters of richness,cover and importance value of ephemeral and ephemeroid plants on south-north and east-west transects in the Gurbantünggüt Desert in early spring,and investigated and analyzed the microhabitats,such as terrain,geomorphology,soil physical-chemical properties and crusts. By comparison,the regional differences in the ephemeral distribution in the desert were revealed. The species of ephemeral plants in the south and center are the richest and those in the west are the poorest in the desert. The cover of ephemeral plants in the mid-south is higher than that in the north,and that in the mid-east is higher than that in the west. The response of ephemeral plants to the spatial variation of the desert habitat forms the population-habitat gradient of ephemeral plants. The characteristics are:(1) In the habitat with higher terrain,coarser textured soil with poorer sorting and correspondingly higher organic matter and lower alkali-saline contents,Carex physoides and Eremopyrum orientale are the dominant ephemeral plants;(2) In the dry habitat with lower terrain,looser textured soil,some organic matter,alkali-saline soil,and developed crust,the ephemeral plants Alyssum linifolium and Erodium oxyrrhynchum are of characteristic of drought and alkali-saline tolerance;(3) In the habitat with lower terrain,some water and more alkali-saline soil,the ephemeral plants Neotorularia torulosa and Hypecoum parviflorum being of alkali-saline tolerance are mainly developed. However,most ephemerals are distributed in a habitat order of higher terrain,some organic,and less alkali-saline soil on the above-mentioned ephemeral population-habitat gradient. The spatial gradient of variation in desert microhabitats is small,and as a whole,the physio-logical character of mesophytism is represented by the desert ephemerals. | QIAN YiBing WU ZhaoNing ZHANG LiYun ZHAO RuiFeng WANG XiaoYan LI YouMin | 2007 | Chinese Science Bulletin2007，52，22： | 16 |
| 3 | Accurate Evaluation of Free-form Surface Profile Error Based on Quasi Particle Swarm Optimization Algorithm and Surface Subdivision显示文摘Although significant progress has been made in precision machining of free-form surfaces recently, inspection of such surfaces remains a difficult problem. In order to solve the problem that no specific standards for the verification of free-form surface profile are available, the profile parameters of free-form surface are proposed by referring to ISO standards regarding form tolerances and considering its complexity and non-rotational symmetry. Non-uniform rational basis spline(NURBS) for describing free-form surface is formulated. Crucial issues in surface inspection and profile error verification are localization between the design coordinate system(DCS) and measurement coordinate system(MCS) for searching the closest points on the design model corresponding to measured points. A quasi particle swarm optimization(QPSO) is proposed to search the transformation parameters to implement localization between DCS and MCS. Surface subdivide method which does the searching in a recursively reduced range of the parameters u and v of the NURBS design model is developed to find the closest points. In order to verify the effectiveness of the proposed methods, the design model is generated by NURBS and the measurement data of simulation example are generated by transforming the design model to arbitrary position and orientation, and the parts are machined based on the design model and are measured on CMM. The profile errors of simulation example and actual parts are calculated by the proposed method. The results verify that the evaluation precision of freeform surface profile error by the proposed method is higher 10%-22% than that by CMM software. The proposed method deals with the hard problem that it has a lower precision in profile error evaluation of free-form surface. | WEN Xiulan ZHAO Yibing WANG Dongxia ZHU Xiaochun XUE Xiaoqiang | 2013 | Chinese Journal of Mechanical Engineering2013，26，2： | 13 |
| 4 | The Coix Genome Provides Insights into Panicoideae Evolution and Papery Hull Domestication显示文摘Coix is a grass crop domesticated as early as the Neolithic era.It is still widely cultivated for both highly nutritional food and medicinal use.However,the genetic study and breeding of this crop are hindered by the lack of a sequenced genome.Here,we report de novo sequencing and assembly of the 1619-Mb genome of Coix,and annotation of 75.39%repeats and 39629 protein-coding genes.Comparative genomics analysis showed that Coix is more closely related to sorghum than maize,but intriguingly only Coix and maize had a recent genome duplication event,which was not detected in sorghum.We further constructed a genetic map and mapped several important traits,especially the strength of hull.Selection of papery hull(thin:easy dehulling)from the stony hull(thick:difficult dehulling)in wild progenitors was a key step in Coix domestication.The papery hull makes seed easier to process and germinate.Anatomic and global transcriptome analysis revealed that the papery hull is a result of inhibition of cell division and wall biogenesis.We also successfully demonstrated that seed hull pressure resistance is controlled by two major quantitative trait loci(QTLs),which are associated with hull thickness and color,respectively.The two QTLs were further fine mapped within intervals of 250 kb and 146 kb,respectively.These resources provide a platform for evolutionary studies and will facilitate molecular breeding of this important crop. | Chao Guo Yanan Wang Aiguo Yang Jun He Chaowen Xiao Shanhua Lv Fengming Han Yibing Yuan Yuan Yuan Xiaolong Dong Juan Guo YawenYang-Hailan Liu Ningzhi Zuo Yaxi Hu Kangxu Zhao Zhengbo Jiang Xing Wang Tingting Jiang Yaou Sherf Moju Cao Yuan Wang Zhaobo Long Tingzhao Rong Luqi Huang Shufeng Zhou | 2020 | Molecular Plant2020，13，2： | 11 |
| 5 | Vegetation patterns and species-environment relationships in the Gurbantunggut Desert of China显示文摘Gurbantunggut 沙漠在中国是最大的马厩和半马厩沙沙漠,还很少数据为这些多样的荒芜的风景在植被模式和种类环境关系上存在。调查区域的沙沙丘主要具有 | QIAN Yibing WU Zhaoning ZHAO Ruifeng ZHANG Liyun | 2008 | Journal of Geographical Sciences2008，18，4： | 10 |
| 6 | Some projectively flat (α,β)-metrics显示文摘In this paper, we study a class of Finsler metrics in the form F = α + ∈β + 2k β2/α-k2β4/3α3 , where α= (√aijyiyj) is a Riemannian metric, β = biyi is a 1-form, and ∈ and k ≠ 0 are constants. We obtain a sufficient and necessary condition for F to be locally projectively flat and give the non-trivial special solutions. Moreover, it is proved that such projectively flat Finsler metrics with the constant flag curvature must be locally Minkowskian. | SHEN Yibing ZHAO Lili | 2006 | Science China Mathematics2006，49，6： | 7 |
| 7 | Mineral compositions in breast milk of healthy Chinese lactating women in urban areas and its associated factors显示文摘 | Zhao Ai Ning Yibing Zhang Yumei Yang Xiaoguang Wang Junkuan Li Wenjun Wang Peiyu | 2014 | Chinese Medical Journal2014，，14： | 7 |
| 8 | Rutile TiO2 Microspheres with Exposed Nano-Acicular Single Crystals for Dye-Sensitized Solar Cells显示文摘有暴露的 nano 针状的单个晶体的特别地结构化的金红石 TiO2 microspheres 成功地经由一个灵巧的热水的方法被综合了。在在 450 点的锻烧以后? | Haimin Zhang Hua Yu Yanhe Han Porun Liu Shanqing Zhang Peng Wang Yibing Cheng Huijun Zhao | 2011 | Nano Research2011，4，10： | 5 |
| 9 | A facile and general approach for the synthesis of fluorescent silica nanoparticles doped with inert dyes显示文摘A general and facile approach was developed for the synthesis of almost monodisperse fluorescent silica nanoparticles (NPs) doped with inert dyes, which are organic fluorophores that are strongly fluorescent but are hydrophobic or lack a covalent binding group. The prepared NPs were mesoporous and the dye molecules were encapsulated in the pores via hydrophobic interaction with the CTAB template. The NPs were stable and highly fluorescent in aqueous solution, and have potential applications in bioanalysis and fluorescence encoding. | MU Xue WU ChuanLiu LAI JinPing CHEN JianBin ZHENG JinSheng LI Chong ZHAO YiBing | 2011 | Chinese Science Bulletin2011，56，31： | 5 |
| 10 | Polydopamine and collagen coated micro-grated polydimethylsiloxane for human mesenchymal stem cell culture显示文摘Natural tissues contain highly organized cellular architecture.One of the major challenges in tissue engineering is to develop engineered tissue constructs that promote cellular growth in physiological directionality.To address this issue,micro-patterned polydimethylsiloxane(PDMS)substrates have been widely used in cell sheet engineering due to their low microfabrication cost,higher stability,excellent biocompatibility,and most importantly,ability to guide cellular growth and patterning.However,the current methods for PDMS surface modification either require a complicated procedure or generate a non-uniform surface coating,leading to the production of poor-quality cell layers.A simple and efficient surface coating method is critically needed to improve the uniformity and quality of the generated cell layers.Herein,a fast,simple and inexpensive surface coating method was analyzed for its ability to uniformly coat polydopamine(PD)with or without collagen on micro-grated PDMS substrates without altering essential surface topographical features.Topographical feature,stiffness and cytotoxicity of these PD and/or collagen based surface coatings were further analyzed.Results showed that the PD-based coating method facilitated aligned and uniform cell growth,therefore holds great promise for cell sheet engineering as well as completely biological tissue biomanufacturing. | Dhavan Sharma Wenkai Jia Fei Long Shweta Pati Qinghui Chen Yibing Qyang Bruce Lee Chang Kyong Choi Feng Zhao | 2019 | Bioactive Materials2019，4，1： | 4 |
| 11 | On fundamental groups of Finsler manifolds In memory of the centenary birthday of Professor S.S.Chern显示文摘In this paper,we study the growth of fundamental groups of Finsler manifolds.Some relationships between the growth of fundamental groups and the volume growth of universal covers of Finsler manifolds are found.Some estimates of entropies and the number of generators of fundamental groups of Finsler manifolds are given.Moreover,the quasi-isometry and the geometric norm in Finsler geometry are considered. | SHEN YiBing ZHAO Wei | 2011 | Science China Mathematics2011，54，9： | 3 |
| 12 | Comparison on effect of hydrophobicity on the antibacterial and antifungal activities of α-helical antimicrobial peptides显示文摘HPRP-A1, a 15-mer α-helical cationic peptide, was derived from N-terminus of ribosomal protein L1 (RpL1) of Helicobacter pylori. In this study, HPRP-A1 was used as a framework to obtain a series of peptide analogs with different hydrophobicity by single amino acid substitutions in the center of nonpolar face of the amphipathic helix in order to systematically study the effect of hydrophobicity on biological activities of -helical antimicrobial peptides. Hydrophobicity and net charge of peptides played key roles in the biological activities of these peptide analogs; HPRP-A1 and peptide analogs with relative higher hydrophobicity exerted broad spectrum antimicrobial activity against Gram-negative bacteria, Gram-positive bacteria and pathogenic fungi, but also showed stronger hemolytic activity; the change of hydrophobicity and net charge of peptides had similar effects with close trend and extent on antibacterial activities and antifungal activities. This indicated that there were certain correlations between the antibacterial mode of action and the antifungal mode of action of these peptides in this study. The peptides exhibited antimicrobial specificity for bacteria and fungi, which provided potentials to develop new antimicrobial drugs for clinical practices. | ZHAO LianJing HUANG YiBing GAO Song CUI Yan HE Dan WANG Li CHEN YuXin | 2013 | Science China Chemistry2013，56，9： | 3 |
| 13 | {001} facets dominated anatase TiO_2 : Morphology, formation/etching mechanisms and performance显示文摘Controllable growth of anatase TiO2 crystals with exposed high reactive crystal facets has aroused great attention in the fields of science and technology due to their unique structure-dependent properties. Recently, much effort has been paid to synthesize anatase TiO2 crystals with exposed high reactive {001} facets. Herein, we review the recent progress in synthesizing {001} facets dominated anatase TiO2 crystals with different morphologies by various synthetic methods. Furthermore, our review is mainly focused on the formation/etching mechanisms of {001} facets dominated anatase TiO2 crystals based on our and other studies. The extensive application potentials of the anatase TiO2 crystals with exposed {001} facets have been summarized in this review such as photocatalysis, photoelectrocatalysis, solar energy conversion, lithium ion battery, and hydrogen generation. Based on the current studies, we give some perspectives on the research topic. We believe that this comprehensive review on anatase TiO2 crystals with high reactive {001} facets can further promote the relative research in this field. | ZHANG HaiMin LIU XiaoLu LI YiBing LI Ying ZHAO HuiJun | 2013 | Science China Chemistry2013，56，4： | 3 |
| 14 | microRNA-21 overexpression contributes to cell proliferation by targetingPTEN in endometrioid endometrial cancer显示文摘 | Xiaoyan Qin Lei Yan Xingbo Zhao Chunyan Li Yibing Fu | 2012 | Oncology Letters2012，，： | 2 |
| 15 | Protection of 3'-methoxy-puerarin against focal brain ischemia and its association with c-fos expression显示文摘The present study established a rat model of focal brain ischemia by occlusion of the middle cerebral artery covered with FeCl3, and investigated the protective effect of 3'-methoxy-puerarin. Hippocampal and cortical c-fos gene expression was determined using in situ hybridization. Results showed that 3'-methoxy-puerarin reduced neurological deficit scores, cerebral infarcted zone and water content of brain tissues, dramatically increased the activity of catalase and glutathione peroxidase in the ischemia zone of the hippocampus, increased the activity of catalase in the cortex, decreased lipid peroxide and lactic acid contents in the hippocampus and cerebral cortex, and down-regulated c-fos gene expression in brain ischemic rats. Results demonstrated that 3'-methoxy-puerarin exhibited cerebroprotective effects against focal brain ischemia, which involved c-fos gene expression. | Sha Liu Yibing Zhang Guiyou Du Yong Zhao Haifeng Cui Chunyu Cao | 2011 | Neural Regeneration Research2011，6，27： | 2 |
| 16 | Progress in the toxicological researches for quantum dots显示文摘Quantum dots (QDs) have received more and more attention as a novel example of nanomaterials. Due to their unique fluorescent characteristics,quantum dots have been successfully applied in biotech-nology and medicine applications. Recently,the toxicity and the potential environmental effects of QDs have become a research hotspot. In this paper,toxicological effects of QDs are reviewed,and the prospects and research directions are given based on the analysis of this research field. | LI HongCheng ZHOU QunFang LIU Wei YAN Bing ZHAO Yibing JIANG GuiBin | 2008 | Science China Chemistry2008，51，5： | 2 |
| 17 | Phosphorus Efficacy in Four Chinese Long-Term Experiments with Different Soil Properties and Climate Characteristics显示文摘 | Linping Zhao Yibing Ma Guoqing Liang Shutian Li Lishu Wu | 2009 | Communications in Soil Science and Plant Analysis . 2009 (19-2)2009，，19： | 1 |
| 18 | Development of a novel rhodamine-type fluorescent probe to determine peroxynitrite显示文摘 | Yang Xiaofeng Guo Xiangqun Zhao Yibing | 2002 | Talanta2002，57，5： | 1 |
| 19 | FWENet:a deep convolutional neural network for flood water body extraction based on SAR images显示文摘As one of the most severe natural disasters in the world,floods caused substantial economic losses and casualties every year.Timely and accurate acquisition of flood inundation extent could provide technical support for relevant departments in the field of flood emergency response and disaster relief.Given the accuracy of existing research works extracting flood inundation extent based on Synthetic Aperture Radar(SAR)images and deep learning methods is relatively low,this study utilized Sentinel-1 SAR images as the data source and proposed a novel model named flood water body extraction convolutional neural network(FWENet)for flood information extraction.Then three classical semantic segmentation models(UNet,Deeplab v3 and UNet++)and two traditional water body extraction methods(Otsu global thresholding method and Object-Oriented method)were compared with the FWENet model.Furthermore,this paper analyzed the water body area change situations of Poyang Lake.The main results of this paper were as follows:Compared with other five water body extraction methods,the FWENet model achieved the highest water body extraction accuracy,its F1 score and mean intersection over union(mIoU)were 0.9871 and 0.9808,respectively.This study could guarantee the subsequent research on flood extraction based on SAR images. | Jingming Wang Shixin Wang Futao Wang Yi Zhou Zhenqing Wang Jianwan Ji Yibing Xiong Qing Zhao | 2022 | International Journal of Digital Earth2022，15，1： | 1 |
| 20 | Synthesis of the clinopyroxenes join CaMgSi2O6- NaAlSi2O6 for jewellery 显示文摘 | Zhao Tinghe Yan Xuewei Cui Shuojing Zhu Yibing | 1995 | Journal of Material Science1995，30，4： | 1 |
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