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| 1 | Mechanism of Kinect-based virtual reality training for motor functional recovery of upper limbs after subacute stroke显示文摘The Kinect-based virtual reality system for the Xbox 360 enables users to control and interact with the game console without the need to touch a game controller,and provides rehabilitation training for stroke patients with lower limb dysfunctions.However,the underlying mechanism remains unclear.In this study,18 healthy subjects and five patients after subacute stroke were included.The five patients were scanned using functional MRI prior to training,3 weeks after training and at a12-week follow-up,and then compared with healthy subjects.The Fugl-Meyer Assessment and Wolf Motor Function Test scores of the hemiplegic upper limbs of stroke patients were significantly increased 3 weeks after training and at the 12-week follow-up.Functional MRI results showed that contralateral primary sensorimotor cortex was activated after Kinect-based virtual reality training in the stroke patients compared with the healthy subjects.Contralateral primary sensorimotor cortex,the bilateral supplementary motor area and the ipsilateral cerebellum were also activated during hand-clenching in all 18 healthy subjects.Our findings indicate that Kinect-based virtual reality training could promote the recovery of upper limb motor function in subacute stroke patients,and brain reorganization by Kinect-based virtual reality training may be linked to the contralateral sensorimotor cortex. | Xiao Bao Yurong Mao Qiang Lin Yunhai Qiu Shaozhen Chen Le Li Ryan S.Cates Shufeng Zhou Dongfeng Huang | 2013 | Neural Regeneration Research2013，8，31： | 15 |
| 2 | The Coix Genome Provides Insights into Panicoideae Evolution and Papery Hull Domestication显示文摘Coix is a grass crop domesticated as early as the Neolithic era.It is still widely cultivated for both highly nutritional food and medicinal use.However,the genetic study and breeding of this crop are hindered by the lack of a sequenced genome.Here,we report de novo sequencing and assembly of the 1619-Mb genome of Coix,and annotation of 75.39%repeats and 39629 protein-coding genes.Comparative genomics analysis showed that Coix is more closely related to sorghum than maize,but intriguingly only Coix and maize had a recent genome duplication event,which was not detected in sorghum.We further constructed a genetic map and mapped several important traits,especially the strength of hull.Selection of papery hull(thin:easy dehulling)from the stony hull(thick:difficult dehulling)in wild progenitors was a key step in Coix domestication.The papery hull makes seed easier to process and germinate.Anatomic and global transcriptome analysis revealed that the papery hull is a result of inhibition of cell division and wall biogenesis.We also successfully demonstrated that seed hull pressure resistance is controlled by two major quantitative trait loci(QTLs),which are associated with hull thickness and color,respectively.The two QTLs were further fine mapped within intervals of 250 kb and 146 kb,respectively.These resources provide a platform for evolutionary studies and will facilitate molecular breeding of this important crop. | Chao Guo Yanan Wang Aiguo Yang Jun He Chaowen Xiao Shanhua Lv Fengming Han Yibing Yuan Yuan Yuan Xiaolong Dong Juan Guo YawenYang-Hailan Liu Ningzhi Zuo Yaxi Hu Kangxu Zhao Zhengbo Jiang Xing Wang Tingting Jiang Yaou Sherf Moju Cao Yuan Wang Zhaobo Long Tingzhao Rong Luqi Huang Shufeng Zhou | 2020 | Molecular Plant2020，13，2： | 11 |
| 3 | Methods of Studying Petroleum Systems in Residual Basins-A Case Study of Mesozoic and Palaeozoic MarineBasins in Southern China显示文摘 | ZHAO Zongju, ZHU Yan, YANG Shufeng, WANG Genghai,XU Yunjun, FENG Jialiang and DENG Hongying Department of Geoscience, Zhejiang University, Hangzhou 310027, Zhejiang Hangzhou Institute of Petroleum Geology, Hangzhou 310023, Zhejiang Zhou Jian Fei Zhenbi | 2002 | Acta Geologica Sinica(English Edition)2002，76，2： | 4 |
| 4 | Pliocene flora and paleoenvironment of Zanda Basin, Tibet, China显示文摘This paper describes a plant megafossil assemblage from the Pliocene strata of Xiangzi, Zanda Basin in the western Qinghai-Tibet Plateau. Twenty-one species belonging to 12 genera and 10 families were identified. Studies show that the Pliocene vegetation in Zanda Basin was mostly deciduous shrub composed of Cotoneaster, Spiraea, Caragana, Hippophae,Rhododendron, Potentilla fruticosa, etc. Leaf sizes of these taxa were generally small. Paleoclimate reconstruction using Coexistence Analysis and CLAMP showed that this area had higher temperature and precipitation in the Pliocene than today, and distinct seasonal precipitation variability was established. The reconstructed paleoelevation of Zanda Basin in the Pliocene was similar to modern times. In the context of central Asian aridification, the gradual drought in the area beginning in the late Cenozoic caused vegetation to transition from shrub to desert, and the flora composition also changed. | Jian HUANG Tao SU Shufeng LI Feixiang WU Tao DENG Zhekun ZHOU | 2020 | Science China Earth Sciences2020，63，2： | 2 |
| 5 | Cloning and characterization of miRNAs from maize seedling roots under low phosphorus stress显示文摘 | Zhiming Zhang Haijian Lin Yaou Shen Jian Gao Kui Xiang Li Liu Haiping Ding Guangsheng Yuan Hai Lan Shufeng Zhou Maojun Zhao Shibin Gao Tingzhao Rong Guangtang Pan | 2012 | Molecular Biology Reports2012，，8： | 1 |
| 6 | Simultaneous determination of the lactone and carboxylate forms of irinotecan (CPT-11) and its active metabolite SN-38 by high-performance liquid chromatography: Application to plasma pharmacokinetic studies in the rat显示文摘 | Xiaoxia Yang Zeping Hu Sui Yung Chan Boon Cher Goh Wei Duan Eli Chan Shufeng Zhou | 2005 | Journal of Chromatography B2005，，2： | 1 |
| 7 | Mechanism of the antiulcerogenic effect of Ganoderma lucidum polysaccharides on indomethacin-induced lesions in the rat显示文摘 | Yihuai Gao Shufeng Zhou Jianbo Wen | 2002 | Life Sciences2002，，6： | 1 |
| 8 | Mechanism of the antiulcerogenic effect of Ganoderma lucidum polysaccharides on indomethacin induced lesions in the rat 显示文摘 | Yihuai Gao Shufeng Zhou Jianbo Wen | 2002 | Life Sciences2002，，6： | 1 |
| 9 | Analysis of long term catalytic performance for isobutane alkylation catalyzed by NMA–AlCl3 based ionic liquid analog显示文摘Isobutane alkylation with 2-butene to produce high-quality gasoline was catalyzed by Nmethylacetamide(NMA)-AlCl3 based ionic liquid(IL) analog with a NMA/AlCl3 molar ratio of 0.75 and CuCl modification,which was marked as CuCl-modified 0.75 NMA-1.0 AlCl3.The long-term experiment was carried out in the autoclave operated in continuous mode to investigate the distribution of alkylate under different experimental nodes.The result indicated that the long-term alkylation was divided into three stages:rising,stable,and descending regions.C8 selectivity and molar ratio of trimethylpentanes(TMPs) to dimethylhexanes(DMHs) reached the highest level in the stable region,and research octane number(RON) of alkylate was as high as 97.Anionic Al species([AlbCl7]^-,[A1 CuC15]^-) and cationic Al species([AlCl2 L]^+) from IL analog as two active Lewis acidic species played a catalytic role in the long-term alkylation,whereas the neutral Al species did not participate into the alkylation.Moreover,the structure of CuCl-modified 0.75 NMA-1.0 AlCl3 was destroyed after the deactivation,and CuCl was enriched in the CD2 Cl2-insoluble substance,resulting in a decreasing TMP/DMH ratio.The catalytic lifetime of IL analog was similar with CuCl-modified 0.55 Et3 NHCl-1.0 AlCl3 IL,but IL analog had a lower cost. | Pengcheng Hu Zhitao Wu Junlin Wang Yuqing Huang Yang Deng Shufeng Zhou | 2019 | Chinese Journal of Chemical Engineering2019，27，8： | 1 |
| 10 | Overexpression ofphytoene synthase gene from Salicorniaeuropaea alters response to reactive oxygen species under salt stress in transgenic Arabidopsis显示文摘 | Han Heping Li Yinxin Zhou Shufeng | 2008 | Biotechnol Lett2008，30，8： | 1 |
| 11 | Cancer Prevention and Treat- ment by Ganoderma, a Mushroom with Medicinal Properties 显示文摘 | Yihuai Gao Shufeng Zhou | 2003 | FOOD REVIEWS INTERNATIONAL2003，19，3： | 1 |
| 12 | A genome wide association study between copy number variation (CNV) and human height in Chinese population显示文摘Copy number variation (CNV) is a type of genetic variation which may have important roles in phenotypic variability and disease susceptibility. To hunt for genetic variants underlying human height variation, we performed a genome wide CNV association study for human height in 618 Chinese unrelated subjects using Affymetrix 500K array set. After adjusting for age and sex, we found that four CNVs at 6p21.3, 8p23.3-23.2, 9p23 and 16p12.1 were associated with human height (with borderline significant p value: 0.013, 0.011, 0.024, 0.049; respectively). However, after multiple tests correction, none of them was associated with human height. We observed that the gain of copy number (more than 2 copies) at 8p23.3-23.2 was associated with lower height (normal copy number vs. gain of copy number: 161.2 cm vs. 153.7 cm, p = 0.011), which accounted for 0.9% of height variation. Loss of copy number (less than 2 copies) at 6p21.3 was associated with 0.8% lower height (loss of copy number vs. normal copy number: 154.5 cm vs. 161.1 cm, p = 0.013). Since no important genes influencing height located in CNVs at loci of 8p23.3-23.2 and 6p21.3, the two CNVs may cause the structural rear- rangements of neighbored important candidate genes, thus regulates the variation of height. Our results expand our knowledge of the genetic factors underlying height variation and the biological regulation of human height. | Xi Li Lijun Tan Xiaogang Liu Shufeng Lei Tielin Yang Xiangding Chen Fang Zhang Yue Fang Yan Guo Liang Zhang Han Yan Feng Pan Zhixin Zhang Yumei Peng Qi Zhou Lina He Xuezhen Zhu Jing Cheng Lishu Zhang Yaozhong Liu Qing Tian Hongwen Deng | 2010 | Journal of Genetics and Genomics2010，37，12： | 1 |
| 13 | Inflammation and cancer stem cells显示文摘 | Sarah Shigdar Yong Li Santanu Bhattacharya Michael O’Connor Chunwen Pu Jia Lin Tao Wang Dongxi Xiang Lingxue Kong Ming Q. Wei Yimin Zhu Shufeng Zhou Wei Duan | 2014 | Cancer Letters2014，，2： | 1 |
| 14 | Modelling the thresholds of nitrogen/phosphorus concentration and hydraulic retention time for bloom control in reclaimed water landscape显示文摘The risks posed by algal blooms caused by nitrogen and phosphorus in reclaimed water used in urban water landscapes need to be carefully controlled.In this study,the combined effects of the nitrogen and phosphorus concentrations and the light intensity and temperature on the specific growth rates of algae were determined using Monod,Steele,and Arrhenius models,then an integrated algal growth model was developed.The algae biomass,nitrogen concentration,and phosphorus concentration mass balance equations were used to establish a new control model describing the nitrogen and phosphorus concentration and hydraulic retention time thresholds for algal blooms.The model parameters were determined by fitting the models to data acquired experimentally.Finally,the control model and numerical simulations for six typical algae and mixed algae under standard conditions were used to determine nitrogen/phosphorus concentration and hydraulic retention time thresholds for landscape water to which reclaimed water is supplied(i.e.,for a reclaimed water landscape). | Keying Song Shufeng Zhu Yun Lu Guohua Dao Yinhu Wu Zhuo Chen Shengnan Wang Junhan Liu Wenguang Zhou Hong-Ying Hu | 2022 | Frontiers of Environmental Science & Engineering2022，16，10： | 1 |
| 15 | Role of P-glycoprotein in the transport of tanshinone I, one active triterpenoid from Salvia miltiorrhiza 显示文摘 | Li Xingxiao Zhou Zhiwei Zhou Shufeng | 2008 | Drug Metab lett2008，2，3： | 1 |
| 16 | Influence of synthesis condition on pore structure of A1 pillared clays and supported Pd catalysts for deep oxida- tion of benzene显示文摘 | Zuo Shufeng Zhou Renxian | 2008 | Micropor Mesopor Mater2008，113，123： | 1 |
| 17 | Simultaneous determination of metformin and gliclazide in human plasma by liquid chromatography - tandem mass spectrometry : application to a bioequivalence study of two formulations in healthy volunteers显示文摘 | ZHONG Guoping BI Huichang ZHOU Shufeng | 2005 | Journal of Mass Spectrometer2005，40，11： | 1 |
| 18 | Inflammation and cancer stem cells显示文摘 | Sarah Shigdar Yong Li Santanu Bhattacharya Michael O’Connor Chunwen Pu Jia Lin Tao Wang Dongxi Xiang Lingxue Kong Ming Q. Wei Yimin Zhu Shufeng Zhou Wei Duan | 2014 | Cancer Letters2014，，2： | 1 |
| 19 | Clinical outcomes and management of mechanism-based inhibition of cytochrome P450 3A4显示文摘 | ZHOU Shufeng CHAN Eli LI Xiaotian | 2005 | Ther Clin Risk Manag2005，1，1： | 1 |
| 20 | Pharmacokinetic interactions of drugs with St John' s wort显示文摘 | ZHOU Shufeng CHANT E PAN Shenquan | 2004 | Journal of Psychopharmacology2004，18，2： | 1 |
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