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| 1 | Crystal structure of ISG54 reveals a novel RNA binding structure and potential functional mechanisms显示文摘刺激干扰素的基因 56 (ISG56 ) 家庭成员在堵住病毒的复制并且然而,调整细胞的功能起重要作用他们的内在的分子的机制大部分是不清楚的。这里,我们在场 ISG54 的水晶结构,有新奇 RNA 有约束力的结构的 ISG56 家庭蛋白质。结构证明 ISG54 单体有 9 tetratricopeptide 像重复的主题和伙伴到形成交换域的 dimers。C 终端部分合拢进超级螺旋状的结构并且在它的内部表面上有一条广泛地断然控告的核苷酸绑定隧道。EMSA 结果证明 ISG54 明确地绑在一些 RNA,例如 adenylate uridylate (AU ) 富有的 RNA,与或没有 5 ′triphosphorylation。Mutagenesis 和功能的研究证明这个 RNA 有约束力的能力对它的抗病毒的活动重要。我们的结果建议位于这干扰素可诱导的基因的抗病毒的活动下面的新机制 56 家庭成员。 | Zhenlin Yang Huanhuan Liang Qian Zhou Ying Li Haiwei Chen Wen Ye Danying Chen Joy Fleming Hongbing Shu Yingfang Liu | 2012 | Cell Research2012，22，9： | 8 |
| 2 | Application of CFD Modeling to Hydrodynamics of CycloBio Fluidized Sand Bed in Recirculating Aquaculture Systems显示文摘To improve the efficiency of a CycloBio fluidized sand bed(CB FSB) in removal of dissolved wastes in recirculating aquaculture systems, the hydrodynamics of solid-liquid flow was investigated using computational fluid dynamics(CFD) modeling tools. The dynamic characteristics of silica sand within the CB FSB were determined using three-dimensional, unsteady-state simulations with the granular Eulerian multiphase approach and the RNG k-ε turbulence model, and the simulation results were validated using available lab-scale measurements. The bed expansion of CB FSB increased with the increase in water inflow rate in numerical simulations. Upon validation, the simulation involving 0.55 mm particles, the Gidaspow correlation for drag coefficient model and the Syamlal-O'Brien correlation for kinetic granular viscosity showed the closest match to the experimental results. The volume fraction of numerical simulations peaked as the wall was approached. The hydrodynamics of a pilot-scale CB FSB was simulated in order to predict the range of water flow to avoid the silica sand overflowing. The numerical simulations were in agreement with the experimental results qualitatively and quantitatively, and thus can be used to study the hydrodynamics of solid-liquid multiphase flow in CB FSB, which is of importance to the design, optimization, and amplification of CB FSBs. | LIU Yao SONG Xiefa LIANG Zhenlin PENG Lei | 2014 | Journal of Ocean University of China2014，13，1： | 8 |
| 3 | Networking retinomorphic sensor with memristive crossbar for brain-inspired visual perception显示文摘Compared to human vision,conventional machine vision composed of an image sensor and processor suffers from high latency and large power consumption due to physically separated image sensing and processing.A neuromorphic vision system with brain-inspired visual perception provides a promising solution to the problem.Here we propose and demonstrate a prototype neuromorphic vision system by networking a retinomorphic sensor with a memristive crossbar.We fabricate the retinomorphic sensor by using WSe_(2)/h-BN/Al_(2)O_(3)van der Waals heterostructures with gate-tunable photoresponses,to closely mimic the human retinal capabilities in simultaneously sensing and processing images.We then network the sensor with a large-scale Pt/Ta/Hf O_(2)/Ta one-transistor-one-resistor(1 T1 R)memristive crossbar,which plays a similar role to the visual cortex in the human brain.The realized neuromorphic vision system allows for fast letter recognition and object tracking,indicating the capabilities of image sensing,processing and recognition in the full analog regime.Our work suggests that such a neuromorphic vision system may open up unprecedented opportunities in future visual perception applications. | Shuang Wang Chen-Yu Wang Pengfei Wang Cong Wang Zhu-An Li Chen Pan Yitong Dai Anyuan Gao Chuan Liu Jian Liu Huafeng Yang Xiaowei Liu Bin Cheng Kunji Chen Zhenlin Wang Kenji Watanabe Takashi Taniguchi Shi-Jun Liang Feng Miao | 2021 | National Science Review2021，8，2： | 5 |
| 4 | A Comparative Study on Hydrodynamic Performance of Double Deflector Rectangular Cambered Otter Board显示文摘In the present work,the hydrodynamic performance of the double deflector rectangular cambered otter board was studied using wind tunnel experiment,flume tank experiment and numerical simulation.Results showed that the otter board had a good hydrodynamic performance with the maximum lift-to-drag ratio(K_(MAX) = 3.70).The flow separation occurred when the angle of attack(AOA) was at 45?,which revealed that the double deflector structure of the otter board can delay the flow separation.Numerical simulation results showed a good agreement with experiment ones,and could predict the critical AOA,which showed that it can be used to study the hydrodynamic performance of the otter board with the advantage of flow visualization.However,the drag coefficient in flume tank was much higher than that in wind tunnel,which resulted in a lower lift-to-drag ratio.These may be due to different fluid media between flume tank and wind tunnel,which result in the big difference of the vortexes around the otter board.Given the otter boards are operated in water,it was suggested to apply both flume tank experiment and numerical simulation to study the hydrodynamic performance of otter board. | XU Qingchang FENG Chunlei HUANG Liuyi XU Jiqiang WANG Lei ZHANG Xun LIANG Zhenlin TANG Yanli ZHAO Fenfang WANG Xinxin | 2018 | Journal of Ocean University of China2018，17，5： | 5 |
| 5 | Significant Effects of Fishing Gear Selectivity on Fish Life History显示文摘Over the past few decades, extreme changes have occurred in the characters of exploited fish populations. The majority of these changes have affected the growth traits of fish life history, which include a smaller size-at-age, an earlier age-at-maturation and among others. Currently, the causes of these life history traits changes still require systematic analyses and empirical studies. The explanations that have been cited are merely expressed in terms of fish phenotypic adaptation. It has been claimed that the original traits of fish can be recovered once the intensity of exploitation of the fish is controlled. Sustained environmental and fishing pressure will change the life history traits of most fish species, so the fish individual's traits are still in small size-at-age and at earlier age-at-maturation in exploited fish populations. In this paper, we expressed our view of points that fishing gear has imposed selectivity on fish populations and individuals as various other environmental factors have done and such changes are unrecoverable. According to the existing tend of exploited fish individual's life history traits, we suggested further researches in this field and provided better methods of fishery management and thereby fishery resources protection than those available early. | LIANG Zhenlin SUN Peng YAN Wei HUANG Liuyi TANG Yanli | 2014 | Journal of Ocean University of China2014，13，3： | 4 |
| 6 | Characterization of Bacterial Community Associated with Four Organs of the Yesso Scallop (Patinopecten yessoensis) by High-Throughput Sequencing显示文摘We used Illumina high-throughput sequencing of PCR-amplified V3-V4 16 S rRNA gene regions to characterize bacterial communities associated with the adductor muscles, gills, gonads and intestines of the Yesso scallop(Patinopecten yessoensis) from waters around Zhangzidao, Dalian, China. Overall, 421,276 optimized reads were classified as 25 described bacterial phyla and 308 genera. Firmicutes, Proteobacteria, Tenericutes, Bacteroidetes, Chlamydiae and Spirochaetae accounted for > 97% of the total reads in the four organs. The bacterial 16 S rDNA sequences assigned to Firmicutes and Proteobacteria were abundant in the adductor muscles, gills and gonads; while reads from Tenericutes were dominant in the intestines, followed by those from Firmicutes, Chlamydiae, Proteobacteria and Bacteroidetes. At the genus level, the dominant genera in the adductor muscles, gills and gonads appeared to be Bacillus, Enterococcus and Lactococcus, whereas Mycoplasma was dominant in the intestines. The relative abundances of Bacillus, Enterococcus, Lactococcus, Alkaliphilus, Raoultella, Paenibacillus and Oceanobacillus were significantly lower in the intestine than in the other three organs. Cluster analysis and principal coordinates analysis of the operational taxonomy units profile revealed significant differences in the bacterial community structure between the intestine and the other three organs. Taken together, these results suggest that scallops have intestine-specific bacterial communities and the adductor muscles, gills and gonads harbor similar communities. The difference in the bacterial community between organs may relate to unique habitats, surroundings, diet and their respective physiological functions. | MA Yuexin LI Ming SUN Jingxian HAO Zhenlin LIANG Jun ZHAO Xuewei | 2019 | Journal of Ocean University of China2019，18，2： | 2 |
| 7 | Study on the downhole permanent low frequency pulsating water injection technique显示文摘Waterflood technique with pressure fluctuation, especially with low, ultra low frequency, changes the continuous water flow into the flow with pressure fluctuation, and can prevent contamination precipitation, formation plugging and Jamin effect. It also can prevent the plugging of water injection well, decrease the pressure of waterflood and increase the rate of water injection. On the basis of the existing eccentric injection mandrel, used the energy storage character of air energy accumulator and the pressure switch character of pressure control valve, fixed the plunger valve for pressure control on the position of blanking plug, then developed one new injection mandrel with low frequency character, which can inject water continuously with low, ultra low frequency. Water fluctuation produced during the water injection affect the formation directly and is useful to break down, prevent plugging and augment injection. | WANG Zhiming QI Zhenlin XUE Liang | 2009 | 石油钻采工艺2009，31，1： | 2 |
| 8 | Spatial and temporal characteristics of trophic structure of the southern Huanghai Sea fish communities显示文摘The spatial and temporal characteristics of trophic structure of fish communities in the southern Huanghai Sea were examined based on the data sampled from bottom trawl surveys conducted during the autumn of 2000 and the spring of 2001.Hierarchical agglomerative cluster method and bootstrap randomization were used to identify significant trophic groups for each fish assemblage in the southern Huanghai Sea.A total of six major trophic groups were identified within this system,which classified predators based upon location in the water column or prey size(i.e.,benthic to pelagic predators or fish to small invertebrate prey predators).The similarity level used to identify significant trophic groups in each assemblage ranged from 24% to 34%.Although planktivores were the dominant trophic group in each assemblage(60%~79%),there were spatial and temporal variations in the trophic structure,which reflected the differences in the abundance and availability of dominant preys.Simplified food webs were constructed to evaluate the most important trophic relationships between the dominant prey taxa and the fishes in each assemblage within this system.Although there were some differences in the key prey species among different food webs,pelagic prey items(mainly euphausiids and copepods)represent the most important energetic link between primary producers and higher trophic level predators.The trophic level for most fishes was between 3 and 4,and the weighted mean trophic level for each assemblage ranged from 3.3 to 3.4.Compared with previous study in the mid-1980s,there was an obvious downward trend in the trophic level for most fish species,which resulted mainly from the fluctuation in key prey species in the Huanghai Sea.The decrease in the importance of Japanese anchovy seems to be offset by other abundant prey species such as Euphausia pacifica and copepods(mainly Calanus sinicus). | XUE Ying JIN Xianshi LIANG Zhenlin YE Zhenjiang | 2008 | Acta Oceanologica Sinica2008，27，4： | 2 |
| 9 | Experimental Study on the Hydrodynamic Characteristics of a Submersible Fish Cage at Various Depths in Waves显示文摘Submersible fish cages can be submerged under the water to mitigate the negative effects that arise from severe sea conditions and improve the growing environment for the farmed fish. Thus they are increasingly applied in offshore aquaculture. To ensure both safety and economic efficiency of submersible fish cages, it is important to determine the optimum submergence depth. In this study, a series of physical model experiments were conducted to investigate the hydrodynamic performance of a submersible fish cage at various submergence depths(1/6, 1/4, 1/3, and 1/2 of the water depth as well as the floating condition for reference) with a model scale of 1:20. The results of the physical model experiment for the different depths were compared to analyze the effects of submergence depths on the mooring line tension and the movement of the floating collar. The results showed that the mooring line tension and the floating collar movement significantly attenuated with increasing submergence depth. However, the attenuation tendency became stable when the fish cage reached a certain depth. According to the results, 1/3 of water depth was determined as the optimal submergence depth of the fish cages. Deeper submergence depths showed no significant advantage from a perspective of the hydrodynamic characteristics of the fish cage. The determination of the optimum submergence depth is beneficial for the structural design and operation safety of submersible net cages. | LIU Shengcong BI Chunwei YANG Hui HUANG Liuyi LIANG Zhenlin ZHAO Yunpeng | 2019 | Journal of Ocean University of China2019，18，3： | 2 |
| 10 | Particle image velocimetry and numerical simulations of the hydrodynamic characteristics of an artificial reef显示文摘 | Jiang Zhaoyang Liang Zhenlin Liu Yang | 2013 | Chinese Journal of Oceanology and Limnology2013，5，31： | 1 |
| 11 | Comparison of six statistical approaches in the selection of appropriate fish growth models显示文摘 | ZHU Lixin LI Lifang LIANG Zhenlin | | 0，，03： | 1 |
| 12 | NHC-gold(Ⅰ)-alkyne complexes induced hepatocellular carcinoma cell death through bioorthogonal activation by palladium complex in living system显示文摘Bioorthogonal reactions can take place in biological environments without interfering with biochemical processes.In this study,Pd(PPh_(3))_(2)Cl_(2)was used as a bioorthogonal catalyst to in situ transform the stable N-heterocyclic carbene(NHC)-gold(Ⅰ)-alkyne complex 5 to its active species which can effectively inhibit thioredoxin reductase(TrxR)and exhibit significant anticancer bioactivity in hepatocellular carcinoma(HCC). | Yunlong Lu Yuanhao Liu Zhenlin Liang Xiaoyan Ma Lijuan Liu Zhenfan Wen Iogann Tolbatov Alessandro Marrone Wukun Liu | 2023 | Chinese Chemical Letters2023，34，9： | 0 |
| 13 | Kinetic-boosted CO_(2) electroreduction to formate via synergistic electric-thermal field on hierarchical bismuth with amorphous layer显示文摘Electrocatalytic converting CO_(2) into chemical products has emerged as a promising approach to achieving carbon neutrality.Herein,we report a bismuth-based catalyst with high curvature terminal and amorphous layer which fabricated via two-step electrodeposition achieves stable formate output in a wide voltage window of 600 mV.The Faraday efficiency(FE) of formate reached up to 99.4% at-0.8 V vs.RHE and it remained constant for more than 92 h at-15 mA cm^(-2).More intriguingly,FE formate of95.4% can be realized at a current density of industrial grade(-667.7 mA cm^(-2)) in flow cell.The special structure promoted CO_(2) adsorption and reduced its activation energy and enhanced the electric-thermal field and K^(+) enrichment which accelerated the reaction kinetics.In situ spectroscopy and theoretical calculation further confirmed that the introduction of amorphous structure is beneficial to adsorpting CO_(2)and stabling*OCHO intermediate.This work provides special insights to fabricate efficient electrocatalysts by means of structural and crystal engineering and makes efforts to realize the industrialization of bismuth-based catalysts. | Bing Yang Junyi Zeng Zhenlin Zhang Lin Meng Donglin Shi Liang Chen Youju Huang | 2024 | Journal of Energy Chemistry2024，90，3： | 0 |
| 14 | Impact of summer moratorium on set-net fi shery in Haizhou Bay,China显示文摘The set-net fi shery resources in Haizhou Bay,China have been over-exploited because of over-fi shing and environmental deterioration.To better understand the current situations and the development trends of fi shery resources,the temporal change of biological characteristics and community compositions were analyzed from 2011 to 2018.Meanwhile,we evaluated the impact of the summer moratorium of marine fi shing(SMMF)on the set-net fi shery.Results show that the mean total length of the six principal species showed varying degrees of decreasing trends,while the changing patterns for the mean weight proportion of the six groups varied.For the whole communities,the similarities of the inter-annual community diversities and compositions were high.SMMF is meaningful to help reproductive success and support recruitment.Every year,the catch per unit eff orts of the six principal species after SMMF were signifi cantly higher than before SMMF except for Octopus ocellatus.The target groups showed a higher mean weight proportion after SMMF than before SMMF in eight years,while the non-target groups were converse.Therefore,the resources of the set-net fi shery are changing in the study periods;and SMMF is an important factor infl uencing biological characteristics and community structure.Despite some challenges,SMMF is still one of the most appropriate policy tools to protect the set-net fi shery resources under the reality of China. | Guangjie FANG Haolin YU Xinmeng WANG Huaxiang SHENG Yanli TANG Changdong LIU Chuanxi CHEN Zhenlin LIANG | 2022 | Journal of Oceanology and Limnology2022，40，4： | 0 |
| 15 | Distribution Characteristics of Fat Greenling(Hexagrammos otakii) Inhabiting Artificial Reefs Around Qiansandao Island, Haizhou Bay, China显示文摘Chinese government has provided vigorous financial supports to artificial reef(AR)projects to repair marine ecosystem.Qiansandao AR,an important AR project of Fishery Resource Restoration Program in Shandong Province,was built during 2002 to 2007.It has enhanced the local fishery harvest and generated positive economic benefits.Fat greenling(Hexagrammos otakii)is a major commercial reef fish in Qiansandao with high economic values.Its distribution characteristics need to be further studied.In this research,we studied the potential influence of environmental variables and distance from ARs on catch per unit effort(CPUE)and body length of fat greenlings.The results showed that the average body length of fat greenlings distributed within 10 m from ARs was longer than that of fat greenlings distributed more than 600 m away from ARs.Body length also increased with the increased salinity,while it declined as temperature increased.The probability of the presence of fat greenling increased when temperature was below 20℃,then it slightly decreased.CPUE decreased as the distance increased.Our results elucidate the potential effects of environmental variables and distance from ARs on the distribution of fat greenling,which may also be helpful to the distribution research of other reef fish species. | WANG Xinmeng SUN Peng TANG Yanli LIANG Zhenlin | 2019 | Journal of Ocean University of China2019，18，5： | 0 |
| 16 | Comparison of 16S rRNA Gene Primers on Studying Microbial Community Composition in Bottom Water and Sediment of Artificial Reefs in Laoshan Bay, China显示文摘Marine microorganisms are indispensable regulators of nutrient cycling and energy flow,which are crucial for artificial reefs(ARs)ecosystems.However,little is known about the microbial communities in the bottom water and sediment of ARs.Studies of microbial diversities have greatly advanced due to the development of high-throughput sequencing technologies,whereas the results may vary significantly due to the primers’choice.This study investigated the influences of two 16S ribosomal RNA gene primer choices(V4 and V3-V4)on microbial community compositions and structures.The results showed that the taxonomic assignment de-tected by primer V3-V4 was higher compared with that obtained by primer V4,whereas microbial community compositions had strong correlations between the two primers.Microbial beta diversities of ARs can be uncovered by both primers,but the relation-ships between communities and environmental parameters were inconsistent.The performances of the two primers for water samples were highly consistent,but the inconformity was evident for sediment samples.Given the relatively lower taxonomic classification of primer V4 for sediment samples,primer V3-V4 was recommended for later studies.With the development and advancement of ARs in China,our findings provide a meaningful reference for ecologists focusing on the microbial diversities and ecological functions of these artificial habitats in the future. | FANG Guangjie YU Haolin SHENG Huaxiang TANG Yanli LIANG Zhenlin | 2022 | Journal of Ocean University of China2022，21，5： | 0 |
| 17 | Polymer Integrated Waveguide Optical Biosensor by Using Spectral Splitting Effect显示文摘 | Xiaonan HAN Xiuyou HAN Yuchen SHAO Zhenlin WU Yuxin LIANG Jie TENG Shuhui BO Geert MORTHIER Mingshan ZHAO | 2017 | Photonic Sensors2017，7，2： | 0 |
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