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| 1 | V2O5 Nanospheres with Mixed Vanadium Valences as High Electrochemically Active Aqueous Zinc-Ion Battery Cathode显示文摘AV4+-V2O5 cathode with mixed vanadium valences was prepared via a novel synthetic method using VOOH as the precursor,and its zinc-ion storage performance was evaluated.The products are hollow spheres consisting of nanoflakes.The V4+-V2O5 cathode exhibits a prominent cycling performance,with a specific capacity of 140 mAhg-1 after 1000 cycles at 10 A g.1,and an excellent rate capability.The good electrochemical performance is attributed to the presence of V4+,which leads to higher electrochemical activity,lower polarization,faster ion diffusion,and higher electrical conductivity than V2O5 without V4+.This engineering strategy of valence state manipulation may pave the way for designing high-performance cathodes for elucidating advanced battery chemistry. | Fei Liu Zixian Chen Guozhao Fang Ziqing Wang Yangsheng Cai Boya Tang Jiang Zhou Shuquan Liang | 2019 | Nano-Micro Letters2019，11，2： | 12 |
| 2 | Simultaneous regulation of cations and anions in an electrolyte for high-capacity, high-stability aqueous zinc–vanadium batteries显示文摘Safe,inexpensive aqueous zinc-ion batteries(AZIBs)are regarded as promising energy storage devices.However,they still face issues,including dissolution and collapse of the cathode as well as H_(2)evolution and the growth of Zn dendrites on the Zn anode.Herein,we simultaneously regulate the cations and anions in the electrolyte for high-capacity,high-stability aqueous zinc–vanadium(Zn–V)batteries based on a bimetallic cation-doped Na_(0.33)K_(0.1)V_(2)O_(5)·nH_(2)O cathode.We demonstrate that Na^(+) cations suppress cathode dissolution and restrain Zn dendrite growth on the anode via an electrostatic shield effect.We also illustrate that ClO_(4)^(-) anions participate in energy storage at the cathode and are reduced to Cl^(-),generating a protective layer on the Zn anode surface and providing a stable interface to decrease Zn dendrites and H_(2)evolution during long-term cycling.When Na^(+) and ClO_(4)^(-) are introduced into an aqueous ZnSO_(4) electrolyte,a Zn/Zn symmetric cell shows durable and reversible Zn stripping/plating for 1500 h at a current density of 1 mA cm^(-2) and with an area capacity of 1 mAh cm^(-2).Zn/Na_(0.33)K_(0.1)V_(2)O_(5)·nH_(2)O full batteries exhibit a high capacity of 600 mAh g^(-1)at 0.1 A g^(-1) and long-term cycling performance for 5000 cycles,with a capacity of 200 mAh g^(-1) at 20 Ag^(-1). | Ziqing Wang Miao Zhou Liping Qin Minghui Chen Zixian Chen Shan Guo Liangbing Wang Guozhao Fang Shuquan Liang | 2022 | eScience2022，2，2： | 8 |
| 3 | Pros and Cons: Autophagy in Acute Spinal Cord Injury显示文摘Autophagy plays an important role in the development and pathogenesis of various diseases. It can be induced by a variety of events such as hypoxia, nutrient-starvation, and mechanical damage. Many neurological disorders such Parkinson’s disease, Alzheimer’s disease, amyotrophic lateral sclerosis, Huntington’s disease, cerebral ischemia, and acute spinal cord injury (ASCI), are closely related to autophagy. However, therapeutic strategies to manipulate autophagy have not yet been fully deciphered due to the limited knowledge of the molecular mechanisms underlying autophagy in these disorders. | Zheng Li Tianshi Chen Yuanwu Cao Xiaoxing Jiang Haodong Lin Jian Zhang Zixian Chen | 2019 | Neuroscience Bulletin2019，35，5： | 6 |
| 4 | 1.3 GHz E-O bandwidth GaN-based micro-LED for multi-gigabit visible light communication显示文摘The data rate of a visible light communication(VLC) system is basically determined by the electrical-to-optical(E-O) bandwidth of its light-emitting diode(LED) source. In order to break through the intrinsic limitation of the carrier recombination rate on E-O bandwidth in conventional c-plane LEDs based on In Ga N quantum wells,a blue micro-LED with an active region of nano-structured In Ga N wetting layer is designed, fabricated, and packaged to realize a high-speed VLC system. The E-O bandwidth of the micro-LED can reach up to 1.3 GHz. Based on this high-speed micro-LED, we demonstrated a data rate of 2 Gbps with a bit error rate(BER) of 1.2×10^(-3) with simple on-off keying signal for a 3-m real-time VLC. In addition, a 4-Gbps VLC system using quadrature phase shift keying-orthogonal frequency-division multiplexing with a BER of 3.2×10^(-3) is also achieved for the same scenario. Among all the point-to-point VLC systems based on a single-pixel LED,this work has the highest distance-bandwidth product of 3 GHz·m and the highest distance-rate product of 12 Gbps·m. | LEI WANG ZIXIAN WEI CHIEN-JU CHEN LAI WANG H.Y.FU LI ZHANG KAI-CHIA CHEN MENG-CHYI WU YUHAN DONG ZHIBIAO HAO YI LUO | 2021 | Photonics Research2021，9，5： | 4 |
| 5 | Effects of metal ions and heat shock on the expression of a metallothionein-like gene htMT2 in Helianthus tuberosus显示文摘The expression of htMT2 in tissues of Helianthus tuberosus treated with metal ions and heat shock is studied by Northern blot hybridization. The results indicate that htMT2 is not expressed in roots. The expression in leaves and stems can be reduced by Cu2+ and induced by low concentration of Zn2+. However, the expression of htMT2 can be suppressed by Zn2+ when its concentrations are above 500 μmol/L. The effects of Ca2+ on the expression of htMT2 in leaves are similar to that of Zn2+. But Ca2+ induces the expression of htMT2 in stems. The expression levels of htMT2 in various tissues are not significantly affected by heat shock. The results above demonstrate that the expression of htMT2 can be regulated by metal ions and confirm that htMT2 is a new metallothionein-like gene. | CHANG Tuanjie, CHEN Lei, CHEN Wanxin, LU Zixian, CHEN Songbiao and ZHU Zhen(Institute of Genetics, Chinese Academy of Sciences, Beijing 100101, China) | 2002 | Progress in Natural Science:Materials International2002，12，7： | 3 |
| 6 | Development of part-dissolvable chitosan fibers with surface N-succinylation for wound care dressing显示文摘 | Guohui SUN Chao FENG Ming KONG Xiaojie CHENG Jiaojiao BING Guixue XIA Zixian BAO Hyunjin PARK Xiguang CHEN | 2015 | Frontiers of Materials Science2015，9，3： | 2 |
| 7 | Single-cell RNA-Seq analysis identified kidney progenitor cells from human urine显示文摘Dear Editor,Urine passes through the entire kidney and urinary tract system starting from the glomerulus and ending to the urethra.Cells in the kidney and urinary tract could be exfoliated from the epithelium into the urine,while leukocyte could infiltrate from the local tissue into the urine,which makes the urine a useful subject for clinical evaluation of relevant diseases. | Yujia Wang Yu Zhao Zixian Zhao Dandan Li Hao Nie Yufen Sun Xiaobei Feng Ting Zhang Yu Ma Jing Nie Guangyan Cai Xiangmei Chen Wei Zuo | 2021 | Protein & Cell2021，12，4： | 2 |
| 8 | Molecular design towards two-dimensional electron acceptors for efficient non-fullerene solar cells显示文摘Non-fullerene polymer solar cells(NF-PSCs) have gained wide attention recently. Molecular design of non-fullerene electron acceptors effectively promotes the photovoltaic performance of NF-PSCs. However,molecular electron acceptors with 2-dimensional(2 D) configuration and conjugation are seldom reported.Herein, we designed and synthesized a series of novel 2 D electron acceptors for efficient NF-PSCs. With rational optimization on the conjugated moieties in both vertical and horizontal direction, these 2 D electron acceptors showed appealing properties, such as good planarity, full-spectrum absorption, high absorption extinction coefficient, and proper blend morphology with donor polymer. A high PCE of 9.76%was achieved for photovoltaic devices with PBDB-T as the donor and these 2 D electron acceptors. It was also found the charge transfer between the conjugated moieties in two directions of these 2 D molecules contributes to the utilization of absorbed photos, resulting in an exceptional EQE of 87% at 730 nm. This work presents rational design guidelines of 2 D electron acceptors, which showed great promise to achieve high-performance non-fullerene polymer solar cells. | Yan Liu Zixian Liu Zhicheng Hu Yuanying Liang Zhenfeng Wang Zhongxin Chen Fei Huang Yong Cao | 2020 | Journal of Energy Chemistry2020，29，12： | 1 |
| 9 | Mechanical Analysis and Performance Optimization for the Lunar Rover’s Vane-Telescopic Walking Wheel显示文摘It is well-known that optimizing the wheel system of lunar rovers is essential.However,this is a difficult task due to the complex terrain of the moon and limited resources onboard lunar rovers.In this study,an experimental prototype was set up to analyze the existing mechanical design of a lunar rover and improve its performance.First,a new vane-telescopic walking wheel was proposed for the lunar rover with a positive and negative quadrangle suspension,considering the complex terrain of the moon.Next,the performance was optimized under the limitations of preserving the slope passage and minimizing power consumption.This was achieved via analysis of the wheel force during movement.Finally,the effectiveness of the proposed method was demonstrated by several simulation experiments.The newly designed wheel can protrude on demand and reduce energy consumption;it can be used as a reference for lunar rover development engineering in China. | Lu Yang Bowen Cai Ronghui Zhang Kening Li Zixian Zhang Jiehao Lei Baichao Chen Rongben Wang | 2020 | Engineering2020，6，8： | 1 |
| 10 | Establishment of a coupled expression system mediated by modified T7 RNA poly-merase gene显示文摘A coupled expression system for plants was established in this study. The 5’-terminal of T7 RNA poly-merase gene was modified by addition of the coding sequence of nuclear location signal from SV40 large T antigen. Plant expression vector pBBT7 was constructed with the modified T7 RNA polymerase gene under the control of CaMV35S promoter. Another expression vector pBTG contained cassette of gusA controlled by T7 promoter. The two vectors were co-transformed into tobacco via the Agrobecte-rium -mediated method. Results of GUS activity indicated that the co-transformed plant with pBBT7 and pBTG showed a high level of GUS activity. The results demonstrated that the coupled expression system of T7 polymerase and T7 promoter was workable in plants. | Feng Chen Zixian Lu Tuanjie Chang Honglin Xu Qian Wu Guifang Xiao Zhen Zhu | 2002 | Chinese Science Bulletin2002，47，14： | 1 |
| 11 | Single-cell transcriptome profiling of the vaginal epithelium reveals the heterogeneity of suprabasal cells显示文摘Dear Editor,The integrity of the vaginal epithelium is crucial for women’s reproductive health and for providing protection against HIV and sexually transmitted infections.1 The vagina is a tubular tract made of fibromuscular and elastic tissue that connects the cervix to the outer genitals.Its main function is to discharge uterine secretions.2 The vaginal epithelium(VE)is a keratinized,stratified squamous epithelium consisting of three layers:the basal layer,the suprabasal layer,and the apical cornified layer. | Chen Liang Zixian Zhao Sarah Liu Ting Zhang Wei Zuo | 2023 | Precision Clinical Medicine2023，6，1： | 0 |
| 12 | ANXA2 Facilitates Enterovirus 71 Infection by Interacting with 3D Polymerase and PI4KB to Assist the Assembly of Replication Organelles显示文摘Similar to that of other enteroviruses, the replication of enterovirus 71(EV71) occurs on rearranged membranous structures called replication organelles(ROs). Phosphatidylinositol 4-kinase Ⅲ(PI4KB), which is required by enteroviruses for RO formation, yields phosphatidylinositol-4-phosphate(PI4P) on ROs. PI4P then binds and induces conformational changes in the RNA-dependent RNA polymerase(Rd Rp) to modulate Rd Rp activity. Here, we targeted 3D polymerase, the core enzyme of EV71 ROs, and found that the host factor Annexin A2(ANXA2) can interact with 3 D polymerase and promote the replication of EV71. Then, an experiment showed that the annexin domain of ANXA2, which possesses membranebinding capacity, mediates the interaction of ANXA2 with EV71 3 D polymerase. Further research showed that ANXA2 is localized on ROs and interacts with PI4KB. Overexpression of ANXA2 stimulated the formation of PI4P, and the level of PI4P was decreased in ANXA2-knockout cells. Furthermore, ANXA2, PI4KB, and 3D were shown to be localized to the viral RNA replication site, where they form a higher-order protein complex, and the presence of ANXA2 promoted the PI4 KB-3D interaction. Altogether, our data provide new insight into the role of ANXA2 in facilitating formation of the EV71 RNA replication complex. | Qiuhan Zhang Siliang Li Ping Lei Zixian Li Feifei Chen Qi Chen Yulu Wang Jiami Gong Qi Tang Xinjin Liu Ke Lan Shuwen Wu | 2021 | Virologica Sinica2021，36，6： | 0 |
| 13 | Community Detection in Blockchain Social Networks显示文摘In this work,we consider community detection in blockchain networks.We specifically take the Bitcoin network and Ethereum network as two examples,where community detection serves in different ways.For the Bitcoin network,we modify the traditional community detection method and apply it to the transaction social network to cluster users with similar characteristics.For the Ethereum network,on the other hand,we define a bipartite social graph based on the smart contract transactions.A novel community detection algorithm which is designed for low-rank signals on graph can help find users’communities based on user-token subscription.Based on these results,two strategies are devised to deliver on-chain advertisements to those users in the same community.We implement the proposed algorithms on real data.By adopting the modified clustering algorithm,the community results in the Bitcoin network are basically consistent with the ground-truth of the betting site community which has been announced to the public.Meanwhile,we run the proposed strategy on real Ethereum data,visualize the results and implement an advertisement delivery on the Ropsten test net. | Sissi Xiaoxiao Wu Zixian Wu Shihui Chen Gangqiang Li Shengli Zhang | 2021 | Journal of Communications and Information Networks2021，6，1： | 0 |
| 14 | Bromocriptine protects perilesional spinal cord neurons from lipotoxicity after spinal cord injury显示文摘Recent studies have revealed that lipid droplets accumulate in neurons after brain injury and evoke lipotoxicity,damaging the neurons.However,how lipids are metabolized by spinal cord neurons after spinal cord injury remains unclear.Herein,we investigated lipid metabolism by spinal cord neurons after spinal cord injury and identified lipid-lowering compounds to treat spinal cord injury.We found that lipid droplets accumulated in perilesional spinal cord neurons after spinal cord injury in mice.Lipid droplet accumulation could be induced by myelin debris in HT22 cells.Myelin debris degradation by phospholipase led to massive free fatty acid production,which increased lipid droplet synthesis,β-oxidation,and oxidative phosphorylation.Excessive oxidative phosphorylation increased reactive oxygen species generation,which led to increased lipid peroxidation and HT22 cell apoptosis.Bromocriptine was identified as a lipid-lowering compound that inhibited phosphorylation of cytosolic phospholipase A2 by reducing the phosphorylation of extracellular signal-regulated kinases 1/2 in the mitogen-activated protein kinase pathway,thereby inhibiting myelin debris degradation by cytosolic phospholipase A2 and alleviating lipid droplet accumulation in myelin debris-treated HT22 cells.Motor function,lipid droplet accumulation in spinal cord neurons and neuronal survival were all improved in bromocriptine-treated mice after spinal cord injury.The results suggest that bromocriptine can protect neurons from lipotoxic damage after spinal cord injury via the extracellular signal-regulated kinases 1/2-cytosolic phospholipase A2 pathway. | Ying Peng Zhuoxuan Li Zhiyang Zhang Yinglun Chen Renyuan Wang Nixi Xu Yuanwu Cao Chang Jiang Zixian Chen Haodong Lin | 2024 | Neural Regeneration Research2024，19，5： | 0 |
| 15 | Arterial spin labeling perfusion MRI applications in drug‑resistant epilepsy and epileptic emergency显示文摘Epilepsy affects all age groups and is one of the most common and disabling neurological disorders worldwide.Drug-resistant epilepsy(DRE),status epilepticus(SE),and sudden unexpected death in epilepsy(SUDEP),which are associated with considerable healthcare costs and mortality,have always been difficult to address and become the focus of clinical research.The rapid identification of seizure onset and accurate localization of epileptic foci are crucial for the treatment and prognosis of people with DRE,SE,or near-SUDEP.However,most of the conventional neuroimaging techniques for assessing cerebral blood flow of people with epilepsy are restricted by time consumption,limited resolution,and ionizing radiation.Arterial spin labeling(ASL)is a newly powerful non-contrast magnetic resonance imaging technique that enables the quantitative evaluation of brain perfusion,characterized by its unique advantages of reproducibility and easy accessibility.Recent studies have demonstrated the potential advantages of ASL for the diagnosis and evaluation of epilepsy.Therefore,in this review,we discussed the complementary value of ASL in evaluating and characterizing the basic substrates underlying refractory epilepsy and epileptic emergencies. | Yingchun Xu Ge Tan Deng Chen Jiao Liu Zixian Zhou Ling Liu | 2023 | Acta Epileptologica2023，6，3： | 0 |
| 16 | Zero Sequence Voltage and Current Control in Four-wire Grids-fed by Grid-forming Inverters显示文摘Low voltage three-phase four-wire AC distribution grids may experience high neutral current,mainly caused by asymmetrical distribution of single-phase loads in three phases.High neutral current will not only increase line losses but also result in neutral potential variations.For the LV AC distribution grid established by a grid-forming inverter(e.g.,uninterruptible power supply and solid-state-transformer),it also suffers from the same neutral current issues.Therefore,this paper comparatively studies several neutral current control approaches and their impacts on grid voltage balance,which is required by grid code.Then,this paper proposes an optimal neutral current control approach,which can obtain maximum neutral current suppression with less impact on grid voltage balance.The correctness of the theoretical analysis is validated through both simulation and experimental results. | Zixian Zhu Wei Chen Vito Giuseppe Monopoli | 2023 | CSEE Journal of Power and Energy Systems2023，9，6： | 0 |
| 17 | An Evaluation of Chinese Human-Computer Dialogue Technology显示文摘There is a growing interest in developing human-computer dialogue systems which is an important branch in the field of artificial intelligence(AI).However,the evaluation of large-scale Chinese human-computer dialogues is still a challenging task.To attract more attention to dialogue evaluation work,we held the fourth Evaluation of Chinese Human-Computer Dialogue Technology(ECDT).It consists of few-shot learning in spoken language understanding(SLU)(Task 1)and knowledge-driven multi-turn dialogue competition(Task 2),the data sets of which are provided by Harbin Institute of Technology and Tsinghua University.In this paper,we will introduce the evaluation tasks and data sets in detail.Meanwhile,we will also analyze the evaluation results and the existing problems in the evaluation. | Zixian Feng Caihai Zhu Weinan Zhang Zhigang Chen Wanxiang Che Minlie Huang Linlin Li | 2021 | Data Intelligence2021，3，2： | 0 |
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