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| 1 | Novel multimodal analgesia regimen improves post-TACE pain in patients with hepatocellular carcinoma显示文摘Backgroud: Transarterial chemoembolization(TACE) is the primary palliative treatment for patients with unresectable hepatocellular carcinoma(HCC). However, it is often accompanied by postoperative pain which hinder patient recovery. This study was to examine whether preemptive parecoxib and sufentanilbased patient controlled analgesia(PCA) could improve the pain management in patients receiving TACE for inoperable HCC. Methods: From June to December 2016, 84 HCC patients undergoing TACE procedure were enrolled. Because of the willingness of the individuals, it is difficult to randomize the patients to different groups. We matched the patients' age, gender and pain scores, and divided the patients into the multimodal group( n = 42) and control group( n = 42). Patients in the multimodal group received 40 mg of parecoxib, 30 min before TACE, followed by 48 h of sufentanil-based PCA. Patients in the control group received a routine analgesic regimen, i.e., 5 mg of dezocine during operation, and 100 mg of tramadol or equivalent intravenous opioid according to patient's complaints and pain intensity. Postoperative pain intensity, percentage of patients as per the pain category, adverse reaction, duration of hospital stay, cost-effectiveness, and patient's satisfaction were all taken into consideration when evaluated. Results: Compared to the control group, the visual analogue scale scores for pain intensity was significantly lower at 2, 4, 6, and 12 h(all P < 0.05) in the multimodal group and a noticeably lower prevalence of post-operative nausea and vomiting in the multimodal group(31.0% vs. 59.5%). Patient's satisfaction in the multimodal group was also significantly higher than that in the control group(95.2% vs. 69.0%). No significant difference was observed in the duration of hospital stay between the two groups. Conclusion: Preemptive parecoxib and sufentanil-based multimodal analgesia regime is a safe, efficient and cost-effective regimen for postoperative pain control in HCC patients undergoing TACE. | Jian-Guo Guo Lu-Ping Zhao Yue-Feng Rao Yin-Ping Gao Xue-Jiao Guo Tan-Yang Zhou Zhi-Ying Feng Jun-Hui Sun Xiao-Yang Lu | 2018 | Hepatobiliary & Pancreatic Diseases International2018，17，6： | 18 |
| 2 | Efficacy of neoadjuvant therapy and surgical rescue for locally advanced hepatoblastomas:10 year single-center experience and literature review显示文摘AIM:To report our experience with long-term outcomes after multimodal management therapy.METHODS:An observational retrospective study was performed containing seven patients with hepatoblastoma(Hbl)treated in our institution,a tertiary referral center,from 2003 to 2011.Demographic,preoperative,surgical,and outcome variables were collected.A survival analysis and a review of the current literature related to combination neoadjuvant chemotherapy and surgical resection on Hbl were performed.RESULTS:The median age at surgery was 14.4 mo,with a male to female ratio of 4:3.Pretext staging at diagnosis was as follows:stageⅠ,4 cases;stageⅡ,2 patients;and stageⅢ,1 case.Mean pretreatment tumor volume was 735 cm3.Five out of seven patients received neoadjuvant chemotherapy according to SIOPEL-3 or SIOPEL-6 protocols.Tumor volume and alphafetoprotein levels significantly dropped after neoadjuvant therapy.Surgical procedures performed included hemihepatectomies,segmentectomies and atypical resection.All patients received chemotherapy after surgery.Median postoperative hospital stay was 8 d.All patients were alive and disease-free after a median follow-up period of 23 mo.With regards to the literature review,seventeen articles were found that were related to our search.CONCLUSION:Our series shows how multimodal management of Hbl,exhaustive control and a meticulous surgical approach leads to almost 100%complete resection with optimal postoperative results. | Dolores Ayllon Teran Oscar Gómez Beltran Rubén Ciria Bru Elena Mateos González María José Pea Rosa Antonio Luque Molina Pedro López Cillero Javier Briceo Delgado | 2014 | World Journal of Gastroenterology2014，20，29： | 12 |
| 3 | A self-organizing multimodal multi-objective pigeon-inspired optimization algorithm显示文摘Multi-objective optimization algorithms have recently attracted much attention as they can solve problems involving two or more conflicting objectives effectively and efficiently. However, most existing studies focus on improving the performance of the solutions in the objective spaces. This paper proposes a novel multimodal multi-objective pigeon-inspired optimization(MMOPIO) algorithm where some mechanisms are designed for the distribution of the solutions in the decision spaces. First, MMOPIO employs an improved pigeon-inspired optimization(PIO) based on consolidation parameters for simplifying the structure of the standard PIO. Second, the self-organizing map(SOM) is combined with the improved PIO for better control of the decision spaces, and thus, contributes to building a good neighborhood relation for the improved PIO.Finally, the elite learning strategy and the special crowding distance calculation mechanisms are used to prevent premature convergence and obtain solutions with uniform distribution, respectively. We evaluate the performance of the proposed MMOPIO in comparison to five state-of-the-art multi-objective optimization algorithms on some test instances, and demonstrate the superiority of MMOPIO in solving multimodal multi-objective optimization problems. | Yi HU Jie WANG Jing LIANG Kunjie YU Hui SONG Qianqian GUO Caitong YUE Yanli WANG | 2019 | Science China(Information Sciences)2019，62，7： | 10 |
| 4 | Multimodal treatment of hepatocellular carcinoma on cirrhosis: An update显示文摘Hepatocellular carcinoma(HCC)is the most frequent primary liver tumor,and overall,it is one of the most frequent cancers.The association of HCC with chronic liver disease,and cirrhosis in particular,is well known,making treatment complex and challenging.The treatment of HCC must take into account the presence and stage of chronic liver disease,with the aim of preserving hepatic function that is often already impaired,the stage of HCC and the clinical condition of the patient.The different treatment options include surgical resection,transplantation,local ablation,chemoembolization,radioembolization and molecular targeted therapies;these treatments can be combined in various ways to achieve different goals.Ideally,liver transplantation is best treatment for early stage HCC on cirrhosis because it removes both the tumor and the chronic disease that produced it;however,the application of this powerful tool is limited by the scarcity of donors.Downstaging and bridging are different strategies for the management of HCC patients who will undergo liver transplantation.Several professionals,including gastroenterologists,radiologists and surgeons,are involved in the choice of the most appropriate treatment for a single case,and a multidisciplinary approach is necessary to optimize the outcome.The purpose of this review is to provide a comprehensive description of the current treatment options for patients with HCC by analyzing the advantages,disadvantages and rationale for their use. | Marco Vivarelli Roberto Montalti Andrea Risaliti | 2013 | World Journal of Gastroenterology2013，19，42： | 9 |
| 5 | 胃的癌症的多模式的治疗显示文摘 Gastric cancer is the second leading cause of death from malignant disease worldwide.Although complete surgical resection remains the only curative modality for early stage gastric cancer,surgery alone only provides long-term survival in 20%of patients with advancedstage disease.To improve current results,it is necessary to consider multimodality treatment,including chemotherapy,radiotherapy and surgery.Recent clinical trials have shown survival benefit of combining different neoadjuvant or adjuvant protocols compared with surgery with curative intent.Furthermore,the implementation of chemotherapy with novel targeted agents could play an important role in the multimodal management of advanced gastric cancer.In this paper,we focus on a multidisciplinary approach in the treatment of gastric cancer and discuss future strategies to improve the outcome for these patients. | Ilaria Proserpio Stefano Rausei Sabrina Barzaghi Francesco Frattini Federica Galli Domenico Iovino Francesca Rovera Luigi Boni Gianlorenzo Dionigi Graziella Pinotti | 2014 | World Journal of Gastrointestinal Surgery2014，6，4： | 8 |
| 6 | Outcome of transarterial chemoembolization-based multi-modal treatment in patients with unresectable hepatocellular carcinoma显示文摘AIM:To investigate the efficacy and safety of transarterial chemoembolization(TACE)-based multimodal treatment in patients with large hepatocellular carcinoma(HCC).METHODS:A total of 146 consecutive patients were included in the analysis,and their medical records and radiological data were reviewed retrospectively.RESULTS:In total,119 patients received TACE-based multi-modal treatments,and the remaining 27 received conservative management.Overall survival(P<0.001)and objective tumor response(P=0.003)were significantly better in the treatment group than in the conservative group.After subgroup analysis,survival benefits were observed not only in the multi-modal treatment group compared with the TACE-only group(P=0.002)but also in the surgical treatment group compared with the loco-regional treatment-only group(P<0.001).Multivariate analysis identified tumor stage(P<0.001)and tumor type(P=0.009)as two independent pre-treatment factors for survival.After adjusting for significant pre-treatment prognostic factors,objective response(P<0.001),surgical treatment(P=0.009),and multi-modal treatment(P=0.002)were identified as independent post-treatment prognostic factors.CONCLUSION:TACE-based multi-modal treatments were safe and more beneficial than conservative management.Salvage surgery after successful downstaging resultedin long-term survival in patients with large,unresectable HCC. | Do Seon Song Soon Woo Nam Si Hyun Bae Jin Dong Kim Jeong Won Jang Myeong Jun Song Sung Won Lee Hee Yeon Kim Young Joon Lee Ho Jong Chun Young Kyoung You Jong Young Choi Seung Kew Yoon | 2015 | World Journal of Gastroenterology2015，21，8： | 7 |
| 7 | palliative care and end-stage colorectal cancer management:The surgeon meets the oncologist显示文摘Colorectal cancer(CRC)is a common neoplasia in the Western countries,with considerable morbidity and mortality.Every fifth patient with CRC presents with metastatic disease,which is not curable with radical intent in roughly 80%of cases.Traditionally approached surgically,by resection of the primitive tumor or stoma,the management to incurable stageⅣCRC patients has significantly changed over the last three decades and is nowadays multidisciplinary,with a pivotal role played by chemotherapy(CHT).This latter have allowed for a dramatic increase in survival,whereas the role of colonic and liver surgery is nowadays matter of debate.Although any generalization is difficult,two main situations are considered,asymptomatic(or minimally symptomatic)and severely symptomatic patients needing aggressive management,including emergency cases.In asymptomatic patients,new CHT regimens allow today long survival in selected patients,also exceeding two years.The role of colonic resection in this group has been challenged in recent years,as it is not clear whether the resection of primary CRC may imply a further increase in survival,thus justifying surgeryrelated morbidity/mortality in such a class of shortliving patients.Secondary surgery of liver metastasis is gaining acceptance since,under new generation CHT regimens,an increasing amount of patients with distant metastasis initially considered non resectable become resectable,with a significant increase in long term survival.The management of CRC emergency patients still represents a major issue in Western countries,and is associated to high morbidity/mortality.Obstruction is traditionally approached surgically by colonic resection,stoma or internal by-pass,although nowadays CRC stenting is a feasible option.Nevertheless,CRC stent has peculiar contraindications and complications,and its long-term cost-effectiveness is questionable,especially in the light of recently increased survival.Perforation is associated with the highest mortality and remains mostly matter for surgeons,by abdominal lavage/drainage,colonic resection and/or stoma.Bleeding and other CRC-related symptoms(pain,tenesmus,etc.)may be managed by several mini-invasive approaches,including radiotherapy,laser therapy and other transanal procedures. | Renato Costi Francesco Leonardi Daniele Zanoni Vincenzo Violi Luigi Roncoroni | 2014 | World Journal of Gastroenterology2014，20，24： | 6 |
| 8 | Clinical outcomes following salvage Gamma Knife radiosurgery for recurrent glioblastoma显示文摘Glioblastoma multiforme(GBM) is the most common malignant primary brain tumor with a survival prognosis of 14-16 mo for the highest functioning patients. Despite aggressive, multimodal upfront therapies, the majority of GBMs will recur in approximately six months. Salvage therapy options for recurrent GBM(r GBM) are an area of intense research. This study compares recent survival and quality of life outcomes following Gamma Knife radiosurgery(GKRS) salvage therapy. Following a Pub Med search for studies usingGKRS as salvage therapy for malignant gliomas, nine articles from 2005 to July 2013 were identified which evaluated rG BM treatment. In this review, we compare overall survival following diagnosis, overall survival following salvage treatment, progression-free survival, time to recurrence, local tumor control, and adverse radiation effects. This report discusses results for rG BM patient populations alone, not for mixed populations with other tumor histology grades. All nine studies reported median overall survival rates(from diagnosis, range:16.7-33.2 mo; from salvage, range:9-17.9 mo). Three studies identified median progression-free survival(range:4.6-14.9 mo). Two showed median time to recurrence of GBM. Two discussed local tumor control. Six studies reported adverse radiation effects(range:0%-46% of patients). The greatest survival advantages were seen in patients who received GKRS salvage along with other treatments, like resection or bevacizumab, suggesting that appropriately tailored multimodal therapy should be considered with each rG BM patient. However, there needs to be a randomized clinical trial to test GKRS for rG BM before the possibility of selection bias can be dismissed. | Erik W Larson Halloran E Peterson Wayne T Lamoreaux Alexander R MacKay Robert K Fairbanks Jason A Call Jonathan D Carlson Benjamin C Ling John J Demakas Barton S Cooke Christopher M Lee | 2014 | World Journal of Clinical Oncology2014，5，2： | 5 |
| 9 | Multimodal Nutrition Education for Cancer Patients显示文摘Globally,30%-40%of cancer patients are at nutritional risk,while about 20%of patients die due to malnutrition rather than the tumor itself.Malnutrition in cancer patients can occur at any stage,thus,it is necessary to carry out multimodal nutrition education on several different occasions.We believe that providing education at three important stages:upon admission,during hospitalization and at discharge can provide a good outcome.Multimodal nutrition education can include materials that are experienced through three different senses:seeing,hearing and touching,and can include online education,offline education,oral education and brochures.This literature review indicated that providing nutrition education can not only improve the nutritional status of cancer patients,but can also improve the ability of patients and their families to manage their own nutrition. | Yin Feng Li Li Xia Zhang Xue Xiao Hong Yi Liao Jing Wang Xiao Li Tang | 2021 | Journal of Nutritional Oncology2021，6，2： | 5 |
| 10 | Analysis of the postoperative hemostatic profile of colorectal cancer patients subjected to liver metastasis resection surgery显示文摘BACKGROUND Liver resection surgery has advanced greatly in recent years,and the adoption of fasttrack programs has yielded good results.Combination anesthesia (general anesthesia associated to epidural analgesia) is an anesthetic-analgesic strategy commonly used for the perioperative management of patients undergoing surgery of this kind,though there is controversy regarding the coagulation alterations it may cause and which can favor the development of spinal hematomas.AIM To study the postoperative course of liver resection surgery,an analysis was made of the outcomes of liver resection surgery due to colorectal cancer metastases in our centre in terms of morbiditymortality and hospital stay according to the anesthetic technique used (general vs combination anesthesia).METHODS A prospective study was made of 61 colorectal cancer patients undergoing surgery due to liver metastases under general and combination anesthesia between January 2014 and October 2015.The patient characteristics,intraoperative variables,postoperative complications,evolution of hemostatic parameters,and stay in intensive care and in hospital were analyzed.RESULTS A total of 61 patients were included in two homogeneous groups: general anesthesia (n = 30) and combination anesthesia (general anesthesia associated to epidural analgesia)(n = 31).All patients had normal coagulation values before surgery.The international normalized ratio (INR) in both the general and combination anesthesia groups reached maximum values at 2448 h (mean 1.37 and 1.45 vs 1.39 and 1.41,respectively),followed by a gradual decrease.There was less intraoperative bleeding in the combination anesthesia group (769 mL) than in the general anesthesia group (1200 mL)(P < 0.05).Of the 61 patients,38.8% in the general anesthesia group experienced some respiratory complication vs 6.6% in the combination anesthesia group (P < 0.001).The time to gastrointestinal tolerance was significantly correlated to the type of anesthesia,though not so the stay in critical care or the time to hospital discharge.CONCLUSION Epidural analgesia in liver resection surgery was seen to be safe,with good results in terms of pain control and respiratory complications,and with no associated increase in complications secondary to altered hemostasis. | Guillermo Perez Navarro Ana Maria Pascual Bellosta Sonia María Ortega Lucea Mario Serradilla Martín Jose Manuel Ramirez Rodriguez Javier Martinez Ubieto | 2019 | World Journal of Clinical Cases2019，7，17： | 4 |
| 11 | Monitoring Value of Multimodal Magnetic Resonance Imaging in Disease Progression of Amyotrophic Lateral Sclerosis: A Prospective Observational Study显示文摘Background: Ongoing efforts have been made to identify new neuroimaging markers to track amyotrophic lateral sclerosis (ALS) progression. This study aimed to explore the monitoring value of multimodal magnetic resonance imaging (MRI) in the disease progression of ALS. Methods: From September 2015 to March 2017, ten patients diagnosed with ALS in Peking Union Medical College Hospital completed head MRI scans at baseline and during follow-up. Multimodal MRI analyses, including gray matter (GM) volume measured by voxel-based morphometry;cerebral blood flow (CBF) evaluated by arterial spin labeling;functional connectivity, including low-frequency fluctuation (fALFF) and regional homogeneity (ReHo), measured by resting-state functional MRI;and integrity of white-matter (WM) fiber tracts evaluated by diffusion tensor imaging, were performed in these patients. Comparisons of imaging metrics were made between baseline and follow-up using paired t-test. Results: In the longitudinal comparisons, the brain structure (GM volume of the right precentral gyri, left postcentral gyri, and right thalami) and perfusion (CBF of the bilateral temporal poles, left precentral gyri, postcentral gyri, and right middle temporal gyri) in both motor and extramotor areas at follow-up were impaired to different extents when compared with those at baseline (all P < 0.05, false discovery rate adjusted). Functional connectivity was increased in the motor areas (fALFF of the right precentral gyri and superior frontal gyri, and ReHo of right precentral gyri) and decreased in the extramotor areas (fALFF of the bilateral middle frontal gyri and ReHo of the right precuneus and cingulate gyri) (all P < 0.001, unadjusted). No significant changes were detected in terms of brain WM measures. Conclusion: Multimodal MRI could be used to monitor short-term brain changes in ALS patients. | Dong-Chao Shen Yin-Yan Xu Bo Hou Hong-Fei Tai Kang Zhang Shuang-Wu Liu Zhi-Li Wang Feng Feng Ming-Sheng Liu Li-Ying Cui | 2018 | Chinese Medical Journal2018，，24： | 4 |
| 12 | Central Pattern Generator(CPG)Control of a Biomimetic Robot Fish for Multimodal Swimming显示文摘This paper introduces the design and control of a biomimetic robot fish for multimodal swimming.The biomimetic design consists of three parts:the rigid head,the wire-driven body and the compliant tail.The control is an improved Central Pattern Generator(CPG)with the high-level control command:(M,co,B,R),where M is the amplitude,co is the angular velocity,B is the offtet and R is the time ratio between two phases forming one flapping cycle.This method differs from previous research in two aspects:(1)The CPG control is firstly implemented on the wire-driven robot fish.(2)The improved CPG model synthesizes symmetrical flapping in cruising and asymmetrical flapping in turning for the robot fish.The asymmetrical flapping refers to the asymmetry of the offset and the time ratio.This combination of the design and the control has several advantages over the existing multimodal swimming robot fishes.First,it uses just one driving motor for undulatory oscillation while the others need to use two or more motors.Second,with just one motor,the CPG control can be easily implemented.Third,the use of the time ratio,R,makes the robot fish turn more naturally and effectively.Experimental results show the robot fish achieved the maximum speed of 1.37 Body Length/Second(BL.s-1)and the largest turning rate of 4577s.Additionally,in many swimming conditions,its Strouhal Number falls in the range from 0.2 to 0.4,which implies the robot fish is efficient. | Fengran Xie Yong Zhong Ruxu Du Zheng Li | 2019 | Journal of Bionic Engineering2019，16，2： | 4 |
| 13 | 在精神分裂症和听觉的幻觉的多模式的 morphometry 和功能的磁性的回声成像显示文摘 AIM:To validate a multimodal[structural and functional magnetic resonance(MR)]approach as coincidence brain clusters are hypothesized to correlate with clinical severity of auditory hallucinations.METHODS:Twenty-two patients meeting Diagnostic and Statistical Manual of Mental Disorders(fourth edition,DSM-Ⅳ)criteria for schizophrenia and experiencing persistent hallucinations together with 28 healthy controls were evaluated with structural and functional MR imaging with an auditory paradigm designed to replicate those emotions related to the patients’hallucinatory experiences.Coincidence maps were obtained by combining structural maps of gray matter reduction with emotional functional increased activation.Abnormal areas were correlated with the brief psychiatric rating scale(BPRS)and the psychotic symptom rating scale(PSYRATS)scales.RESULTS:The coincidence analysis showed areas with coexistence gray matter reductions and emotional activation in bilateral middle temporal and superior temporal gyri.Significant negative correlations between BPRS and PSYRATS scales were observed.BPRS scores were negatively correlated in the middle temporal gyrus(right)(t=6.86,P=0.001),while negative PSYRATS correlation affected regions in both the superior temporal gyrus(left)(t=7.85,P=0.001)and middle temporal gyrus(left)(t=4.97,P=0.002).CONCLUSION:Our data identify left superior and middle temporal gyri as relevant areas for the understanding of auditory hallucinations in schizophrenia.The use of multimodal approaches,sharing structural and functional information,may demonstrate areas specifically linked to the severity of auditory hallucinations. | Gracián García-Martí Eduardo Jesús Aguilar Luis Martí-Bonmatí M José Escartí Julio Sanjuán | 2012 | World Journal of Radiology2012，4，4： | 3 |
| 14 | Risk for emerging bipolar disorder, variants, and symptoms in children with attention deficit hyperactivity disorder, now grown up显示文摘AIM: To determine the prevalence of bipolar disorder(BD) and sub-threshold symptoms in children with attention deficit hyperactivity disorder(ADHD) through 14 years' follow-up, when participants were between 21-24 years old.METHODS: First, we examined rates of BD type Ⅰ?and Ⅱ diagnoses in youth participating in the NIMH-funded Multimodal Treatment Study of ADHD(MTA). We used the diagnostic interview schedule for children(DISC), administered to both parents(DISC-P) and youth(DISCY). We compared the MTA study subjects with ADHD(n = 579) to a local normative comparison group(LNCG, n = 289) at 4 different assessment points: 6, 8, 12, and 14 years of follow-ups. To evaluate the bipolar variants, we compared total symptom counts(TSC) of DSM manic and hypomanic symptoms that were generated by DISC in ADHD and LNCG subjects. Then we sub-divided the TSC into pathognomonic manic(PM) and non-specific manic(NSM) symptoms. We compared the PM and NSM in ADHD and LNCG at each assessment point and over time. We also evaluated the irritability as category A2 manic symptom in both groups and over time. Finally, we studied the irritability symptom in correlation with PM and NSM in ADHD and LNCG subjects.RESULTS: DISC-generated BD diagnosis did not differ significantly in rates between ADHD(1.89%) and LNCG 1.38%). Interestingly, no participant met BD diagnosis more than once in the 4 assessment points in 14 years. However, on the symptom level, ADHD subjects reported significantly higher mean TSC scores: ADHD 3.0; LNCG 1.7; P < 0.001. ADHD status was associated with higher mean NSM: ADHD 2.0 vs LNCG 1.1; P < 0.0001. Also, ADHD subjects had higher PM symptoms than LNCG, with PM means over all time points of 1.3 ADHD; 0.9 LNCG; P = 0.0001. Examining both NSM and PM, ADHD status associated with greater NSM than PM. However, Over 14 years, the NSM symptoms declined and changed to PM over time(df 3, 2523; F = 20.1; P < 0.0001). Finally, Irritability(BD DSM criterion-A2) rates were significantly higher in ADHD than LNCG(χ2 = 122.2, P < 0.0001), but irritability was associated more strongly with NSM than PM(df 3, 2538; F = 43.2; P < 0.0001).CONCLUSION: Individuals with ADHD do not appear to be at significantly greater risk for developing BD, but do show higher rates of BD symptoms, especially NSM. The greater linkage of irritability to NSM than to PM suggests caution when making BD diagnoses based on irritability alone as one of 2(A-level) symptoms for BD diagnosis, particularly in view of its frequent presentation with other psychopathologies. | Ahmed Z Elmaadawi Peter S Jensen L Eugene Arnold Brooke SG Molina Lily Hechtman Howard B Abikoff Stephen P Hinshaw Jeffrey H Newcorn Laurence Lee Greenhill James M Swanson Cathryn A Galanter | 2015 | World Journal of Psychiatry2015，5，4： | 3 |
| 15 | Multi-feature Multimodal Biometric Recognition Based on Quaternion Locality Preserving Projection显示文摘This paper proposed Quaternion locality preserving projection(QLPP)for multi-feature multimodal biometric recognition.Multi-features fill the real part or the three imaginary parts of quaternion to constitute the quaternion fusion features.In quaternion division ring,QLPP extracts the local information and finds essential manifold structure of the quaternion fusion features.Deferent from Quaternion principal component analysis(QPCA)and Quaternion fisher discriminant analysis(QFDA),QLPP takes advantage of the optimal linear approximations to find the nonlinear manifold structures.Two experiments are designed:one fuses four features from two biometric modalities,and the other fuses three features from three biometric modalities.The experimental results show the proposed algorithm achieves much better performance than the unimodal biometric algorithms,the traditional feature level fusion methods(weighted sum rule and series rule)and two quaternion representation methods(QPCA and QFDA). | WANG Zhifang ZHEN Jiaqi LI Yanchao LI Guoqiang HAN Qi | 2019 | Chinese Journal of Electronics2019，28，4： | 3 |
| 16 | IBPSO-Based MUSIC Algorithm for Broken Rotor Bars Fault Detection of Induction Motors显示文摘In spectrum analysis of induction motor current, the characteristic components of broken rotor bars(BRB) fault are often submerged by the fundamental component. Although many detection methods have been proposed for this problem, the frequency resolution and accuracy are not high enough so that the reliability of BRB fault detection is a ected. Thus, a new multiple signal classification(MUSIC) algorithm based on particle swarm intelligence search is developed. Since spectrum peak search in MUSIC is a multimodal optimization problem, an improved bare?bones particle swarm optimization algorithm(IBPSO) is proposed first. In the IBPSO, a modified strategy of subpopulation determination is introduced into BPSO for realizing multimodal search. And then, the new MUSIC algorithm, called IBPSO?based MUSIC, is proposed by replacing the fixed?step traversal search with IBPSO. Meanwhile, a simulation signal is used to test the e ectiveness of the proposed algorithm. The simulation results show that its frequency precision reaches 10^(-5), and the computational cost is only comparable to that of traditional MUSIC with 0.1 search step. Finally, the IBPSO?based MUSIC is applied in BRB fault detection of an induction motor, and the e ectiveness and superiority are proved again. The proposed research provides a modified MUSIC algorithm which has su cient frequency precision to detect BRB fault in induction motors. | Pan-Pan Wang Xiao-Xiao Chen Yong Zhang Yong-Jun Hu Chang-Xin Miao | 2018 | Chinese Journal of Mechanical Engineering2018，31，5： | 2 |
| 17 | Hepatocellular carcinoma: Surgeon's view on latest findings and future perspectives显示文摘Hepatocellular carcinoma(HCC) is the most common liver-derived malignancy with a high fatality rate. Risk factors for the development of HCC have been identified and are clearly described. However, due to the lack of tumor-specific symptoms, HCC are diagnosed at progressed tumor stages in most patients, and thus curative therapeutic options are limited. The focus of this review is on surgical therapeutic options which can be offered to patients with HCC with special regard to recent findings, not exclusively focused on surgical therapy, but also to other treatment modalities. Further, potential promising future perspectives for the treatment of HCC are discussed. | Jan Erik Slotta Otto Kollmar Volker Ellenrieder B Michael Ghadimi Kia Homayounfar | 2015 | World Journal of Hepatology2015，7，9： | 2 |
| 18 | Multimodal Emotion Recognition with Transfer Learning of Deep Neural Network显示文摘Due to the lack of large-scale emotion databases,it is hard to obtain comparable improvement in multimodal emotion recognition of the deep neural network by deep learning,which has made great progress in other areas.We use transfer learning to improve its performance with pretrained models on largescale data.Audio is encoded using deep speech recognition networks with 500 hours’speech and video is encoded using convolutional neural networks with over 110,000 images.The extracted audio and visual features are fed into Long Short-Term Memory to train models respectively.Logistic regression and ensemble method are performed in decision level fusion.The experiment results indicate that 1)audio features extracted from deep speech recognition networks achieve better performance than handcrafted audio features;2)the visual emotion recognition obtains better performance than audio emotion recognition;3)the ensemble method gets better performance than logistic regression and prior knowledge from micro-F1 value further improves the performance and robustness,achieving accuracy of 67.00%for“happy”,54.90%for“an?gry”,and 51.69%for“sad”. | HUANG Jian LI Ya TAO Jianhua YI Jiangyan | 2017 | ZTE Communications2017，15，B12： | 2 |
| 19 | Stability of γ′ multimodal microstructure in a Ni-based powder metallurgy superalloy显示文摘Multimodal size distribution of γ′ phase was obtained in a slow-cooling experiment following supersolvus solution treatment(1191°C). The morphology of the secondary γ′ particles exhibited splitting and protrusion instabilities. In the subsequent aging process(815°C), reverse coarsening was observed, i.e., the average precipitate size decreased with increasing aging time.Reverse coarsening slows the coarsening rate of the precipitates, increases the hardness of the alloy, and greatly improves the morphological stability of the γ′ phase. | ZHANG Ming LIU GuoQuan WANG Hao HU BenFu | 2018 | Science China(Technological Sciences)2018，61，12： | 2 |
| 20 | Advances in therapeutics for liver metastasis from colorectal cancer显示文摘The evolution of chemotherapeutic regimens that include targeted molecular agents has resulted in a breakthrough in the management of advanced colorectal liver metastasis (CLM), improving the progression-free survival after liver resection, and rendering initially unresectable liver tumors resectable, with reported resection rates ranging from 13% to 51%. In addition, the criteria used for selecting patients for hepatectomy have been expanding because of advances in surgical techniques and improvements in chemotherapy. However, the increasing use of chemotherapy has raised concern about potential hepatotoxicities such as steatosis, chemotherapy-associated steatohepatitis, and sinusoidal obstruction syndrome, and their deleterious effects on postoperative outcome. The present review focuses on the advantages and disadvantages of chemotherapy, strategies for the prevention and diagnosis of chemotherapy-associated liver injury, and the adoption of more aggressive surgical approaches, which have changed the traditional paradigm for CLM. | Akira Kobayashi Shinichi Miyagawa | 2010 | World Journal of Gastrointestinal Oncology2010，2，10： | 2 |
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