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| 1 | One-day versus two-day cleansing for colon capsule endoscopy: a prospective randomized pilot study显示文摘 | Laura Ramos Onofre Alarcón Zaida Adrian Antonio Z. Gimeno-García David Nicolás-Pérez Alejandro Jiménez-Sosa Enrique Quintero | 2013 | Gastroenterologia y Hepatologia2013，，： | 2 |
| 2 | Percutaneous biliary metal wall stent-ing in malignant obstructive jaundice显示文摘 | Adrian A Indara Dileep N | 2003 | Euro J Gastroenterol&Hepatol2003，15，8： | 1 |
| 3 | Percutaneous biliary metal wall stenting in malignant obstructive jaundice显示文摘 | Adrian A Indar Dileep N Lobo Andrew D Gilliam Roger Gregson Ian Davidson Simon Whittaker John Doran Brian J Rowlands Ian J Beckingham | 2003 | European Journal of Gastroenterology & Hepatology2003，，： | 1 |
| 4 | Oil transport in surfzone显示文摘 | CHENG N S LAW W K ADRIAN A N | 2000 | Journal of hydraulic enginerring2000，，： | 1 |
| 5 | Overview of interleukin-18: more than an interferon-γ inducing factor 显示文摘 | CHARLES A D DANIELA N ADRIAN J P | 1998 | Journal of Leukocyte Biology1998，63，： | 1 |
| 6 | Understory abundance, species diversity and functional attribute response to thinning in coniferous stands显示文摘 | Adrian A Andrew R N Klaus J P | 2010 | Forest Ecology and Management2010，260，7： | 1 |
| 7 | Percutaneous biliary metal wall stenting in malignant obstructive jaundice显示文摘 | Adrian A Indara Dileep N | 2003 | J Euro Gastroenterol & Hepatol2003，15，8： | 1 |
| 8 | Anal pressures impaired by stapler insertion during colorectal anastomosis 显示文摘 | Ho Yik - Hong F Tan Margaret A N Leong Adrian M | 1999 | Dis Colon Rectum1999，42，1： | 1 |
| 9 | Percutaneous biliary metal wall stenting in malignant obstructive jaundice显示文摘 | Adrian A Indara Dileep N | 2003 | Euro J Gastroenterol & Hepatol2003，15，8： | 1 |
| 10 | Potential effects of future land-use change on regional carbon stocks in the UK显示文摘 | Elena C Adrian C N Ross A H | 2011 | Environmental Science & Policy2011，14，1： | 1 |
| 11 | Clinical applicability and prognostic significance of molecular response assessed by fluorescent‐ PCR of immunoglobulin genes in multiple myeloma. Results from a GEM / PETHEMA study显示文摘 | Joaquin Martinez‐Lopez Elena Fernández‐Redondo Ramón García‐Sánz María Angeles Montalbán Pilar Martínez‐Sánchez Bruno Pavia María Victoria Mateos Laura Rosi?ol Marisa Martín Rosa Ayala Rafael Martínez María Jesus Blanchard Adrian Alegre Joan Besalduch Joa | 2013 | Br J Haematol2013，，5： | 1 |
| 12 | Percutaneous biliary metal wall stenting in malignant obstructive jaundice显示文摘 | Adrian A Indara Dileep N | 2003 | Euro J Gastroenterol &Hepatol2003，15，8： | 1 |
| 13 | Impacts of communi- ty-based conservation on local communities in the AnnapumaConservation Area, Nepal显示文摘 | Siddhartha B B Peter A F Adrian C N | 2006 | Biodiversity and Conservation2006，3，： | 1 |
| 14 | Anaerobic biotransformation of explosives in aquifer slurries amended with ethanol and propylene glycol显示文摘 | Adrian N R Ciint M A | 2007 | Chemosphere2007，66，： | 1 |
| 15 | Numerical and experimental studies of simple geometries in slam- ming 显示文摘 | Adrian C Aboulghit E M A Alain N | 2011 | International Journal of Offshore and Polar Engineering2011，21，3： | 1 |
| 16 | 扩散边界:R.I.房屋显示文摘该项目中的房屋设计是在建造过程中逐渐形成的,在施工中确定当前的结构,而最终用途还未确定。客户家庭期待建成的建筑物,可让他们在周末的时候享受这个风景秀丽之地,远离城市喧嚣,但不确定是要建一个具有野外烧烤功能的凉亭、周末小屋、第二套住宅还是另一个办公室。 | Adrian Moreno María Samaniego Jorge Durán María Gracia Borja Andrea Cisneros Bicubik Sebastián Crespo Andrés Fernández | 2019 | 世界建筑导报2019，34，2： | 0 |
| 17 | Commitment of human mesenchymal stromal cells to skeletal lineages is independent of their morphogenetic capacity显示文摘BACKGROUND Mesenchymal stromal cells(MSCs)are multipotent cell populations obtained from fetal and adult tissues.They share some characteristics with limb bud mesodermal cells such as differentiation potential into osteogenic,chondrogenic,and tenogenic lineages and an embryonic mesodermal origin.Although MSCs differentiate into skeletal-related lineages in vitro,they have not been shown to selforganize into complex skeletal structures or connective tissues,as in the limb.In this work,we demonstrate that the expression of molecular markers to commit MSCs to skeletal lineages is not sufficient to generate skeletal elements in vivo.AIM To evaluate the potential of MSCs to differentiate into skeletal lineages and generate complex skeletal structures using the recombinant limb(RL)system.METHODS We used the experimental system of RLs from dissociated-reaggregated human placenta(PL)and umbilical cord blood(UCB)MSCs.After being harvested and reaggregated in a pellet,cultured cells were introduced into an ectodermal cover obtained from an early chicken limb bud.Next,this filled ectoderm was grafted into the back of a donor chick embryo.Under these conditions,the cells received and responded to the ectoderm’s embryonic signals in a spatiotemporal manner to differentiate and pattern into skeletal elements.Their response to differentiation and morphogenetic signals was evaluated by quantitative poly-merase chain reaction,histology,immunofluorescence,scanning electron microscopy,and in situ hybridization.RESULTS We found that human PL-MSCs and UCB-MSCs constituting the RLs expressed chondrogenic,osteogenic,and tenogenic molecular markers while differentially committing into limb lineages but could not generate complex structures in vivo.MSCs-RL from PL or UCB were committed early to chondrogenic lineage.Nevertheless,the UCB-RL osteogenic commitment was favored,although preferentially to a tenogenic cell fate.These findings suggest that the commitment of MSCs to differentiate into skeletal lineages differs according to the source and is independent of their capacity to generate skeletal elements or connective tissue in vivo.Our results suggest that the failure to form skeletal structures may be due to the intrinsic characteristics of MSCs.Thus,it is necessary to thoroughly evaluate the biological aspects of MSCs and how they respond to morphogenetic signals in an in vivo context.CONCLUSION PL-MSCs and UCB-MSCs express molecular markers of differentiation into skeletal lineages,but they are not sufficient to generate complex skeletal structures in vivo. | Jessica Cristina Marín-Llera Damián García-García Estefania Garay-Pacheco Victor Adrian Cortes-Morales Juan Jose Montesinos-Montesinos Jesus Chimal-Monroy | 2023 | World Journal of Stem Cells2023，15，7： | 0 |
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