|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Relationship between angiotensin-(1-7) and angiotensin Ⅱ correlates with hemodynamic changes in human liver cirrhosis显示文摘AIM:To measure circulating angiotensins at different stages ofhuman cirrhosis and to further evaluate a possible relationship between renin angiotensin system (RAS) components and hemodynamic changes.METHODS: Patients were allocated into 4 groups: mild-to-moderate liver disease (MLD), advanced liver disease (ALD), patients undergoing liver transplantation, and healthy controls. Blood was collected to determine plasma renin activity (PRA), angiotensin (Ang) , Ang Ⅱ, and Ang-(1-7) levels using radioimmunoassays. During liver transplantation, hemodynamic parameters were determined and blood was simultaneously obtained from the portal vein and radial artery in order to measure RAS components.RESULTS: PRA and angiotensins were elevated in ALD when compared to MLD and controls (P < 0.05). In contrast, Ang was signicantly reduced in MLD. Ang-(1-7)/Ang Ⅱ ratios were increased in MLD when compared to controls and ALD. During transplantation, Ang Ⅱ levels were lower and Ang-(1-7)/Ang Ⅱ ratios were higher in the splanchnic circulation than in the peripheral circulation (0.52 ± 0.08 vs 0.38 ± 0.04, P < 0.02), whereas the peripheral circulating Ang /Ang ratio was elevated in comparison to splanchnic lev-els (0.18 ± 0.02 vs 0.13 ± 0.02, P < 0.04). Ang-(1-7)/Ang Ⅱ ratios positively correlated with cardiac output (r= 0.66) and negatively correlated with systemic vascular resistance (r =-0.70).CONCLUSION: Our ndings suggest that the relation-ship between Ang-(1-7) and Ang Ⅱmay play a role in the hemodynamic changes ofhuman cirrhosis. | Walkíria Wingester Vilas-Boas Antnio Ribeiro-Oliveira Jr Regina Maria Pereira Renata da Cunha Ribeiro Jerusa Almeida Ana Paula Nadu Ana Cristina Simoes e Silva Robson Augusto Souza dos Santos | 2009 | World Journal of Gastroenterology2009，15，20： | 11 |
| 2 | Effect of propranolol on the splanchnic and peripheral renin angiotensin system in cirrhotic patients显示文摘AIM:To evaluate the effect of β-blockade on angiotensins in the splanchnic and peripheral circulation of cirrhotic patients and also to compare hemodynamic parameters during liver transplantation according to propranolol pre-treatment or not. METHODS:Patients were allocated into two groups:outpatients with advanced liver disease(LD) and during liver transplantation(LT). Both groups were subdivided according to treatment with propranolol or not. Plasma was collected through peripheral venipuncture to determine plasma renin activity(PRA),Angiotensin(Ang) Ⅰ,Ang Ⅱ,and Ang-(1-7) levels by radioimmunoassay in LD group. During liver transplantation,hemodynamic parameters were determined and blood samples were obtained from the portal vein to measure renin angiotensin system(RAS) components.RESULTS:PRA,Ang Ⅰ,Ang Ⅱ and Ang-(1-7) were signifi cantly lower in the portal vein and periphery in all subgroups treated with propranolol as compared to non-treated. The relationships between Ang-(1-7) and Ang Ⅰ levels and between Ang Ⅱ and Ang Ⅰ were significantly increased in LD group receiving propranolol. The ratio between Ang-(1-7) and Ang Ⅱ remained unchanged in splanchnic and peripheral circulation in patients under β-blockade,whereas the relationship between Ang Ⅱ and Ang Ⅰ was significantly increased in splanchnic circulation of LT patients treated with propranolol. During liver transplantation,cardiac output and index as well systemic vascular resistance and index were reduced in propranolol-treated subgroup. CONCLUSION:In LD group,propranolol treatment reduced RAS mediators,but did not change the ratio between Ang-(1-7) and Ang Ⅱ in splanchnic and peripheral circulation. Furthermore,the modification of hemodynamic parameters in propranolol treated patients was not associated with changes in the angiotensin ratio. | Walkíria Wingester Vilas-Boas Antnio Ribeiro-Oliveira Jr Renata da Cunha Ribeiro Renata Lúcia Pereira Vieira Jerusa Almeida Ana Paula Nadu Ana Cristina Sim■es e Silva Robson Augusto Souza Santos | 2008 | World Journal of Gastroenterology2008，14，44： | 2 |
| 3 | In vitro assessment of Metarhizium anisopliae isolates to control the cattle tick Boophilus microplus 显示文摘 | Ana Paula G F habajara da S V J Aoi M | 2000 | Veterinary Parasitology2000，91，： | 1 |
| 4 | Anti-Ageing Cosmetics: Facts and Controversies显示文摘 | Marcia Ramos-e-Silva Livia Celem Stella Ramos-e-Silva Ana Paula Fucci da Costa | 2013 | Clinics in Dermatology2013，，： | 1 |
| 5 | Comparative evaluation of calcium hypochlorite and sodium hypochlorite associated with passive ultrasonic irrigation on antimicrobial activity of a root canal system infected with enterococcus faecalis: an in vitro study 显示文摘 | Ana Paula DA Matheus Albino S Daniela Cristina M | 2014 | Journal of Endodontics2014，40，12： | 1 |
| 6 | VSUMM: A mechanism designed to produce static video summaries and a novel evaluationmethod 显示文摘 | De Avila Sandra Eliza Fontes Lopes Ana Paula Brandao da Luz Jr Antonio | 2011 | Pattern Recognition Letters2011，32，1： | 1 |
| 7 | Dietary corn germ containing pheytic acid prevents pork meat lipid oxidation while maintaining normal animal growth performance显示文摘 | Ana Paula R Harbach Mara C R da Costa | 2007 | Food Chemistry2007，100，： | 1 |
| 8 | Antifungal Activity of Decyl Gallate against Several Species of Pathogenic Fungi显示文摘 | Ana Carolina Alves de Paula e Silva Caroline Barcelos Costa-Orlandi Fernanda Patrícia Gullo Fernanda Sangalli-Leite Haroldo Cesar de Oliveira Julhiany de Fátima da Silva Liliana Scorzoni Nayla de Souza Pitangui Suélen Andrea Rossi Tatiane Benaducci Vaness | 2014 | Evidence-Based Complementary and Alternative Medicine2014，，： | 1 |
| 9 | Medicinal plants from the Brazilian Amazonian region and their antileishmanial activity:a review显示文摘Leishmaniasis, a neglected disease caused by Leishmania protozoans, primarily affects people in tropical and subtropical areas. Chemotherapy based on the use of pentavalent antimonials, amphotericin B,paromomycin, miltefosine and liposomal amphotericin B is currently the only effective treatment.However, adverse effects, long-term treatment and the emergence of parasite resistance have led to the search for alternative treatments. Natural products used in traditional medicine provide an unlimited source of molecules for the identification of new drugs, and the Amazon region has abundant biodiversity that includes several species of plants and animals, providing a rich source of new products and compounds. Although the literature describes numerous promising compounds and extracts for combating Leishmania protozoans, the results of such research have not been embraced by the pharmaceutical industry for the development of new drugs. Therefore, this review focused on the antileishmanial activity of extracts, isolated compounds and essential oils commonly used by the local population in the Brazilian Amazonian region to treat several illnesses and described in the literature as promising compounds for combating leishmaniasis. | Bruno Jose Martins Da Silva Amanda Anastacia Pinto Hage Edilene Oliveira Silva Ana Paula Drummond Rodrigues | 2018 | Journal of Integrative Medicine2018，16，4： | 1 |
| 10 | In vitro assess-ment of Metarhizium anisopliaeisolates to control the cattle tickBoophilus microplus 显示文摘 | Ana Paula G F Itabajara da S V J Aoi M | 2000 | Veterinary Parasitology2000，94，11： | 1 |
| 11 | Chondrolysis of the hip in an adolescent : clinical and radiological outcomes 显示文摘 | Ana Paula Sakamotoa Larissa Lucati Ramosb Artur da Rocha Correa Fernandesc | 2013 | Rev Bras Reumatol2013，53，2： | 1 |
| 12 | Chlorogenic acids from Tithonia diversifolia demonstrate better anti-inflammatory effect than indomethacin and its sesquiterpene lactones显示文摘 | Daniela Aparecida Chagas-Paula Rejane Barbosa de Oliveira Vanessa Cristina da Silva Leonardo Gobbo-Neto Thaís Helena Gasparoto Ana Paula Campanelli Lúcia Helena Faccioli Fernando Batista Da Costa | 2011 | Journal of Ethnopharmacology2011，，2： | 1 |
| 13 | Syngas Production from Crude Glycerol Using Pyrolysis显示文摘 | Ana Paula Gimenez Peres Nivea de Lima da Silva Mafia Regina Wolf Maciel Rubens Maciel Filho | 2011 | Journal of Chemistry and Chemical Engineering2011，5，2： | 1 |
| 14 | Physical, Meehanical, and Thermal Performance of Cement - Stabilized Rammed Earth - Rice Husk Ash Walls 显示文摘 | Ana Paula da Silva Milani | 2012 | Journal of Materials In Civil Engineering2012，24，6： | 1 |
| 15 | Regulated on Activation, Normal T Cell Expressed and Secreted (RANTES) Antagonist (Met-RANTES) Controls the Early Phase of Trypanosoma cruzi–Elicited Myocarditis显示文摘 | Ana Paula M.P. Marino Andréa da Silva Paula dos Santos Luzia Maria de Oliveira Pinto Ricardo Tostes Gazzinelli Mauro Martins Teixeira Joseli Lannes-Vieira | 2004 | Circulation2004，，11： | 1 |
| 16 | Molecular thermochemical study of Ni(II), Cu(II) and Zn(II) complexes with N,N ′-bis(salicylaldehydo)ethylenediamine显示文摘 | Maria D.M.C. Ribeiro da Silva Jorge M. Gon?alves Ana L.R. Silva Paula C.F.C. Oliveira Bernd Schr?der Manuel A.V. Ribeiro da Silva | 2004 | Journal of Molecular Catalysis A Chemical2004，，1： | 1 |
| 17 | An AFLP marker linked to the Pm-1 gene that confers resistance to Podosphaera xanthii race 1 in Cucumis melo显示文摘 | TEIXEIRA ANA PAULA MATOSO BARRETO FATIMA APARECIDA DA SILVA | 2008 | Genetics and Molecular Biology2008，31，2： | 1 |
| 18 | Evidence that AKT and GSK-3β pathway are involved in acute hyperhomocysteinemia显示文摘 | Aline A. da Cunha Ana Paula Horn Juliana B. Hoppe Patrícia B. Grudzinski Samanta O. Loureiro Andréa G.K. Ferreira Maira J. da Cunha Felipe Schmitz Christianne G. Salbego Angela T.S. Wyse | 2012 | International Journal of Developmental Neuroscience2012，，5： | 1 |
| 19 | In vitro assess-ment of Metarhizium anisopliaeisolates to control the cattle tickBoophilus microplus显示文摘 | Ana Paula G F Itabajara da S V J Aoi M | 2000 | Veterinary Parasitology2000，94，： | 1 |
| 20 | Integrating species and successional classes for wood production in a mixed forest restoration system in a neotropical region显示文摘As forests in neotropical regions,particularly in developing countries,are devastated,interventions to restore biodiversity and its ecological functions are needed.Rural producers have thus been encouraged to grow trees for wood production as an economic activity.The objective of this study was to quantify the increment of wood density of four forest species from different successional classes of a mixed system of restoration in a neotropical forest in Brazil.Tree discs were sampled at breast height and analyzed radially by X-ray densitometry to obtain apparent density and basic density.Three trees each of a species from the pioneer,early and late secondary successional stages and of the dominant species in the climax community.The radial profiles indicated increasing density from the pith to bark of trunks,except for some variations due to wood defects and growth.Average density was 0.576 g cm^(-3),0.655 g cm^(-3),0.706 g cm^(-3)and 0.775 g cm^(-3),respectively,for Peltophorum dubium,Schinus terebinthifolius,Cariniana estrellensis and Hymenaea courbaril.Radial profiles indicated higher amplitudes in the apparent densities for slow-growing species.X-ray densitometry generated parameters such as minimum,average and maximum densities,and radial density variations.These parameters are important for understanding the ecological functional role of successional classes of the Atlantic Forest from the Neotropical region. | Ananias Francisco Dias Junior Ana Lucia Martins Sodero Pincelli Ana Paula Camara da Silva Alison Moreira da Silva Natalia Dias de Souza Mario Tommasiello Filho Jose Otavio Brito | 2021 | Journal of Forestry Research2021，32，6： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员