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| 1 | Transcranial Doppler ultrasonography: From methodology to major clinical applications显示文摘Non-invasive Doppler ultrasonographic study of cerebral arteries [transcranial Doppler(TCD)] has been extensively applied on both outpatient and inpatient settings. It is performed placing a low-frequency(≤ 2 MHz) transducer on the scalp of the patient over specific acoustic windows, in order to visualize the intracranial arterial vessels and to evaluate the cerebral blood flow velocity and its alteration in many different conditions. Nowadays the most widespread indication for TCD in outpatient setting is the research of right to left shunting, responsable of so called 'paradoxical embolism', most often due to patency of foramen ovale which is responsable of the majority of cryptogenic strokes occuring in patients younger than 55 years old. TCD also allows to classify the grade of severity of such shunts using the so called 'microembolic signal grading score'. In addition TCD has found many useful applications in neurocritical care practice. It is useful on both adults and children for day-to-day bedside assessment of critical conditions including vasospasm in subarachnoidal haemorrhage(caused by aneurysm rupture or traumatic injury), traumatic brain injury, brain stem death. It is used also to evaluate cerebral hemodynamic changes after stroke. It also allows to investigate cerebral pressure autoregulation and for the clinical evaluation of cerebral autoregulatory reserve. | Antonello D'Andrea Marianna Conte Massimo Cavallaro Raffaella Scarafile Lucia Riegler Rosangela Cocchia Enrica Pezzullo Andreina Carbone Francesco Natale Giuseppe Santoro Pio Caso Maria Giovanna Russo Eduardo Bossone Raffaele Calabrò | 2016 | World Journal of Cardiology2016，8，7： | 10 |
| 2 | New fecal test for non-invasive Helicobacter pylori detection:A diagnostic accuracy study显示文摘AIM To assess the diagnostic accuracy of a new fecal test for detecting Helicobacter pylori(H. pylori), using ^(13)Curea breath test as the reference standard, and explore bacterial antibiotic resistance. METHODS We conducted a prospective two-center diagnostic test accuracy study. We enrolled consecutive people≥ 18 years without previous diagnosis of H. pylori infection, referred for dyspepsia between February and October 2017. At enrollment, all participants underwent 13 C-urea breath test. Participants aged over 50 years were scheduled to undergo upper endoscopy with histology. Participants collected stool samples 1-3 d after enrollment for a new fecal investigation(THD fecal test). The detection of bacterial 23 S rRNA subunit gene indicated H. pylori infection. We also used the index diagnostic test to examine mutations conferring resistance to clarithromycin and levofloxacin. Independent investigators analyzed index test and reference test standard results blinded to the other test findings. We estimated sensitivity, specificity, positive(PPV) and negative(NPV) predictive value, diagnostic accuracy, positive and negative likelihood ratio(LR), together with 95% confidence intervals(CI).RESULTS We enrolled 294 consecutive participants(age: Median 37.0 years, IQR: 29.0-46.0 years; men: 39.8%). Ninetyfive(32.3%) participants had a positive ^(13)C-urea breath test. Twenty-three(7.8%) participants underwent upper endoscopy with histology, with a full concordance between ^(13)C-urea breath test and histology in detecting H. pylori infection. Four(1.4%) out of the 294 participants withdrew from the study after the enrollment visit and did not undergo THD fecal testing. In the 290 participants who completed the study, the THD fecal test sensitivity was 90.2%(CI: 84.2%-96.3%), specificity 98.5%(CI:96.8%-100%), PPV 96.5%(CI: 92.6%-100%), NPV 95.6%(CI: 92.8%-98.4%), accuracy 95.9%(CI: 93.6%-98.2%), positive LR 59.5(CI: 19.3-183.4), negative LR 0.10(CI: 0.05-0.18). Out of 83 infected participants identified with the THD fecal test, 34(41.0%) had bacterial genotypic changes consistent with antibiotic-resistant H. pylori infection. Of these, 27(32.5%) had bacterial strains resistant to clarithromycin, 3(3.6%) to levofloxacin, and 4(4.8%) to both antibiotics. CONCLUSION The THD fecal test has high performance for the non-invasive diagnosis of H. pylori infection while additionally enabling the assessment of bacterial antibiotic resistances. | Andrea Iannone Floriana Giorgio Francesco Russo Giuseppe Riezzo Bruna Girardi Maria Pricci Suetonia C Palmer Michele Barone Mariabeatrice Principi Giovanni FM Strippoli Alfredo Di Leo Enzo Ierardi | 2018 | World Journal of Gastroenterology2018，24，27： | 5 |
| 3 | Laparoscopic and open surgical treatment of left-sided pancreatic lesions: clinical outcomes and cost-effectiveness analysis显示文摘 | Paolo Limongelli Andrea Belli Gianluca Russo Luigi Cioffi Alberto D’Agostino Corrado Fantini Giulio Belli | 2012 | Surgical Endoscopy2012，，7： | 4 |
| 4 | Estrogen receptors expression in long-lasting ulcerative pancolitis with and without dysplasia: A preliminary report显示文摘 | Mariabeatrice Principi Nicola De Tullio Maria Principia Scavo Domenico Piscitelli Andrea Marzullo Silvana Russo Francesca Albano Katia Lofano Samanta Papagni Michele Barone Enzo Ierardi Alfredo Di Leo | 2012 | Scandinavian Journal of Gastroenterology2012，，10： | 2 |
| 5 | Laparoscopic hand-assisted right hemihepatectomy by ultrasound-directed intrahepatic approach显示文摘 | Giulio Belli Alberto D’Agostino Corrado Fantini Andrea Belli Luigi Cioffi Paolo Limongelli Gianluca Russo | 2009 | Journal of Hepato-Biliary-Pancreatic Surgery2009，，： | 1 |
| 6 | Genetic Mechanisms in Interval Colon Cancers显示文摘 | James M. Richter Maria Simona Pino Thomas R. Austin Emily Campbell Jackie Szymonifka Andrea L. Russo Theodore S. Hong Darrell Borger A. John Iafrate Daniel C. Chung | 2014 | Digestive Diseases and Sciences2014，，9： | 1 |
| 7 | Neo-glycoconjugates:Stereoselective synthesis of o-glycosyl amides via staudinger ligation reactions显示文摘 | ALDO BIANCHI ANDREA RUSSO | 2005 | Tetrahedron:Asymmetry2005，16，： | 1 |
| 8 | Static Balancing of Parallel Robots 显示文摘 | RUSSO Andrea SINATRA Rosario XI Fengfeng | 2005 | Mechanism and Machine Theory2005，40，2： | 1 |
| 9 | Carvedilol increases two-year survivalin dialysis patients with dilated cardiomyopathy显示文摘 | Gennaro Cice Luigi Ferrara Antonello D'Andrea Salvatore D'Isa Attilio Di Benedetto Antonio Cittadini Pina Elvira Russo Paolo Golino Raffaele Calabrò | 2003 | Journal of the American College of Cardiology2003，，9： | 1 |
| 10 | Static balancing of parallel robots显示文摘 | Andrea Russo Rosario Sinatra Fengfeng Xi | 2005 | Mechanism and Machine Theory2005，2，： | 1 |
| 11 | Noninvasive Diagnosis of Electroanatomic Abnormalities in Arrhythmogenic Right Ventricular Cardiomyopathy显示文摘 | Pasquale Santangeli Maurizio Pieroni Antonio Dello Russo Michela Casella Gemma Pelargonio Andrea Macchione Antonia Camporeale Costantino Smaldone Stefano Bartoletti Luigi Di Biase Fulvio Bellocci Andrea Natale | 2010 | Circulation: Arrhythmia and Electrophysiology2010，，6： | 1 |
| 12 | Histological Substrate of Atrial Biopsies in Patients With Lone Atrial Fibrillation显示文摘 | Andrea Frustaci Cristina Chimente Fulvio Bellocci Emanuela Morgante Matteo A. Russo Attilio Maseri | 1997 | Circulation1997，，4： | 1 |
| 13 | Disability, more than multimorbidity, was predictive of mortality among older persons aged 80 years and older显示文摘 | Francesco Landi Rosa Liperoti Andrea Russo Ettore Capoluongo Christian Barillaro Marco Pahor Roberto Bernabei Graziano Onder | 2010 | Journal of Clinical Epidemiology2010，，7： | 1 |
| 14 | Repeat liver surgery by laparoscopy for a malignant recurrence after previous open or laparoscopic resection显示文摘Aim:This paper reported the experience of one center on repeat laparoscopic liver surgery for metastasis and hepatocellular carcinoma(HCC)with a review of the literature.Methods:This retrospective study included 24 patients who underwent laparoscopic re-intervention(hepatic resection and radiofrequency ablation)for recurrent HCC in cirrhosis(n=17)and for recurrent malignant metastases(n=7)after a previous open or laparoscopic procedure.Patients were divided into two groups according to the fi rst surgical approach.Group 1 underwent open resection and laparoscopic procedure(7 patients),and Group 2 underwent laparoscopic resection and laparoscopic procedure(17 patients).Results:Mean operative time for re-intervention was signifi cantly longer for Group 1(220.14±80.06 min)than for Group 2(150±56.18 min;P=0.001),whereas the mean blood loss and mean hospital stay were comparable in both groups.According to Dindo-Clavien classifi cation,overall morbidity ranged between Grade I and IIIa and was similar in both groups.Conclusion:This study suggests that repeat laparoscopic surgery for recurrent hepatic malignant diseases in selected patients is a feasible and safe procedure with good short-term outcomes,but further prospective studies are needed to support these results. | Luigi Cioffi Andrea Belli Corrado Fantini Alberto D’Agostino Gianluca Russo Giulio Belli | 2015 | Hepatoma Research2015，1，1： | 1 |
| 15 | Midarm muscle circumference, physical performance and mortality: Results from the aging and longevity study in the Sirente geographic area (ilSIRENTE study)显示文摘 | Francesco Landi Andrea Russo Rosa Liperoti Marco Pahor Matteo Tosato Ettore Capoluongo Roberto Bernabei Graziano Onder | 2009 | Clinical Nutrition2009，，4： | 1 |
| 16 | Microvolt T-Wave Alternans Distinguishes Between Patients Likely and Patients Not Likely to Benefit From Implanted Cardiac Defibrillator Therapy: A Solution to the Multicenter Automatic Defibrillator Implantation Trial (MADIT) II Conundrum显示文摘 | Daniel M. Bloomfield Richard C. Steinman Pearila B. Namerow Michael Parides Jorge Davidenko Elizabeth S. Kaufman Timothy Shinn Anne Curtis John Fontaine Douglas Holmes Andrea Russo Chuen Tang J Thomas Bigger | 2004 | Circulation2004，，14： | 1 |
| 17 | The role of UGT1A1 , 28 polymorphism in the pharmacodynamics and pharmacokinetics of irinotecan in patients with metastatic colorectal cancer显示文摘 | Toffoli G Cecchin E Corona G Russo A Buonadonna A D'Andrea M etal | 2006 | J Clin Oncol2006，24，19： | 1 |
| 18 | Single-Agent Pemetrexed or Sequential Pemetrexed/Gemcitabine as Front-Line Treatment of Advanced Non-small Cell Lung Cancer in Elderly Patients or Patients Ineligible for Platinum-Based Chemotherapy: A Multicenter, Randomized, Phase II Trial显示文摘 | Cesare Gridelli Eckhard Kaukel Vanessa Gregorc Maria Rita Migliorino Thomas R. Müller Christian Manegold Adolfo Favaretto Andrea Martoni Orazio Caffo Alexander Schmittel Antonio Rossi Francesca Russo Patrick Peterson María Mu?oz Martin Reck | 2007 | Journal of Thoracic Oncology2007，，3： | 1 |
| 19 | Covalent functionalization of decellularized tissues accelerates endothelialization显示文摘In the field of tissue regeneration,the lack of a stable endothelial lining may affect the hemocompatibility of both synthetic and biological replacements.These drawbacks might be prevented by specific biomaterial functionalization to induce selective endothelial cell(EC)adhesion.Decellularized bovine pericardia and porcine aortas were selectively functionalized with a REDV tetrapeptide at 10^(-5)M and 10^(-6)M working concentrations.The scaffold-bound peptide was quantified and REDV potential EC adhesion enhancement was evaluated in vitro by static seeding of human umbilical vein ECs.The viable cells and MTS production were statistically higher in functionalized tissues than in control.Scaffold histoarchitecture,geometrical features,and mechanical properties were unaffected by peptide anchoring.The selective immobilization of REDV was effective in accelerating ECs adhesion while promoting proliferation in functionalized decellularized tissues intended for blood-contacting applications. | Eleonora Dal Sasso Annj Zamuner Andrea Filippi Filippo Romanato Tiziana Palmosi Luca Vedovelli Dario Gregori Jose Luís Gòmez Ribelles Teresa Russo Antonio Gloria Laura Iop Gino Gerosa Monica Dettin | 2021 | Bioactive Materials2021，6，11： | 1 |
| 20 | Staticbalancing of parallel robots显示文摘 | Russo Andrea Sinatra Rosario Xi Fengfeng | 2005 | Mechanism and MachineTheory2005，40，2： | 1 |
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