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| 1 | A lead isotopic study of the human bioaccessibility of lead in urban soils from Glasgow, Scotland显示文摘 | John G. Farmer Andrew Broadway Mark R. Cave Joanna Wragg Fiona M. Fordyce Margaret C. Graham Bryne T. Ngwenya Richard J.F. Bewley | 2011 | Science of the Total Environment2011，，23： | 1 |
| 2 | Determination of the bioaccessibility of chromium in Glasgow soil and the implications for human health risk assessment 显示文摘 | Andrew Broadway Mark R Cave Joanna Wragg | 2010 | Science of The Total Environment2010，409，2： | 1 |
| 3 | Determination of the bioaccessibility of chromium in Glasgow soil and the implications for human health risk assessment显示文摘 | Broadway Andrew Cave Mark R Wragg Joanna | | 0，，02： | 1 |
| 4 | Determination of the bioaccessibility of chromium in Glasgow soil and the implications for human health risk assessment显示文摘 | Andrew Broadway Mark R. Cave Joanna Wragg Fiona M. Fordyce Richard J.F. Bewley Margaret C. Graham Bryne T. Ngwenya John G. Farmer | 2010 | Science of the Total Environment2010，，2： | 1 |
| 5 | 冠状动脉介入治疗稳定性心绞痛ORBITA挑战心脏病专家,在选择经皮冠状动脉介入治疗的患者时要更加严格显示文摘十余年前,随机临床试验COURAGE研究显示,经皮冠状动脉介入治疗(PCI)未能降低已接受最佳药物治疗的稳定性冠心病患者的死亡或心肌梗死风险。PCI对延缓动脉粥样硬化病变进展无效,但却成为临床最常用的恢复冠状动脉灌注和缓解劳力性心绞痛的治疗方法。 | Adam Timmis Andrew Wragg 刘冬(译) 袁建松(校) | 2019 | 英国医学杂志中文版2019，22，4： | 0 |
| 6 | VEGFR1/CXCR4-positive progenitor cells modulate local inflammation and augment tissue perfusion by a SDF-1-dependent mechanism显示文摘Recruitment and retention of circulating progenitor cells at the site of injured or ischemic tissues facilitates adult neovascularization.We hypothesized that cell therapy could modulate local neo-vascularization through the vascular endothelial growth factor(VEGF)/stromal cellderived factor-1(SDF-1)axis and by paracrine effects on local endothelial cells.We isolated from rat bone marrow a subset of multipotent adult progenitor cell-derived progenitor cells(MDPC).In vitro,MDPCs secreted multiple cytokines related to inflammation and angiogenesis,including monocyte chemotactic protein-1,SDF-1,basic fibroblast growth factor,and VEGF,and expressed the chemokine receptors CXCR4 and VEGFR1.To investigate in vivo properties,we transplanted MDPCs into the ischemic hind limbs of rats.Elevated levels of the chemokine SDF-1 and colocalization of CD11b^+cells marked the initial phase of tissue remodeling after cell transplantation.Prolonged engraftment was observed in the adventitial-medial border region of arterioles of ischemic muscles.However,engrafted cells did not differentiate into endothelial or smooth muscle cells.Limb perfusion normalized 4 weeks after cell injection.Inhibition of SDF-1 reduced the engraftment of transplanted cells and decreased endothelial cell proliferation.These findings suggest a two-stage model whereby transplanted MDPCs modulate wound repair through recruitment of inflammatory cells to ischemic tissue.This is an important potential mechanism for cell transplantation,in addition to the direct modulation of local vascular cells through paracrine mechanisms. | Andrew Wragg Jason A.Mellad Leilani E.Beltran Mikhail Konoplyannikov Hong San Sherry Boozer Robert J.Deans Anthony Mathur Robert J.Lederman Jason C.Kovacic Manfred Boehm | 2016 | 世界最新医学信息文摘2016，16，2： | 0 |
| 7 | VEGFR1/CXCR4-positive progenitor cells modulate local inflammation and augment tissue perfusion by a SDF-1-dependent mechanism显示文摘Recruitment and retention of circulating progenitor cells at the site of injured or ischemic tissues facilitates adult neovascularization. We hypothesized that cell therapy could modulate local neo-vascularization through the vascular endothelial growth factor(VEGF)/stromal cellderived factor-1(SDF-1) axis and by paracrine effects on local endothelial cells. We isolated from rat bone marrow a subset of multipotent adult progenitor cell-derived progenitor cells(MDPC). In vitro, MDPCs secreted multiple cytokines related to inflammation and angiogenesis, including monocyte chemotactic protein-1, SDF-1, basic fibroblast growth factor, and VEGF, and expressed the chemokine receptors CXCR4 and VEGFR1. To investigate in vivo properties, we transplanted MDPCs into the ischemic hind limbs of rats. Elevated levels of the chemokine SDF-1 and colocalization of cd11b+ cells marked the initial phase of tissue remodeling after cell transplantation. Prolonged engraftment was observed in the adventitial–medial border region of arterioles of ischemic muscles. However, engrafted cells did not differentiate into endothelial or smooth muscle cells. Limb perfusion normalized 4 weeks after cell injection. Inhibition of SDF-1 reduced the engraftment of transplanted cells and decreased endothelial cell proliferation. These findings suggest a two-stage model whereby transplanted MDPCs modulate wound repair through recruitment of inflammatory cells to ischemic tissue. This is an important potential mechanism for cell transplantation, in addition to the direct modulation of local vascular cells through paracrine mechanisms. | Andrew Wragg Jason A.Mellad Leilani E.Beltran Mikhail Konoplyannikov Hong San Sherry Boozer Robert J.Deans Anthony Mathur Robert J.Lederman Jason C.Kovacic Manfred Boehm | 2015 | 世界最新医学信息文摘2015，15，99： | 0 |
| 8 | 治疗心绞痛的新药显示文摘心绞痛是心肌缺血所致的疼痛,通常由阻塞性冠状动脉疾病所致.虽然典型心绞痛表现为劳力性胸痛,但患者也可有不典型症状, | Daniel A Jones Adam Timmis Andrew Wragg 苏冠华(译) 李景东(校) | 2014 | 英国医学杂志中文版2014，，1： | 0 |
| 9 | VEGFR1/CXCR4-positive progenitor cells modulate local inflammation and augment tissue perfusion by a SDF-1-dependent mechanism显示文摘Recruitment and retention of circulating progenitor cells at the site of injured or ischemic tissues facilitates adult neovascularization. We hypothesized that cell therapy could modulate local neo-vascularization through the vascular endothelial growth factor(VEGF)/stromal cellderived factor-1(SDF-1) axis and by paracrine effects on local endothelial cells. We isolated from rat bone marrow a subset of multipotent adult progenitor cell-derived progenitor cells(MDPC). In vitro, MDPCs secreted multiple cytokines related to inflammation and angiogenesis, including monocyte chemotactic protein-1, SDF-1, basic fibroblast growth factor, and VEGF, and expressed the chemokine receptors CXCR4 and VEGFR1. To investigate in vivo properties, we transplanted MDPCs into the ischemic hind limbs of rats. Elevated levels of the chemokine SDF-1 and colocalization of cd11b+ cells marked the initial phase of tissue remodeling after cell transplantation. Prolonged engraftment was observed in the adventitial–medial border region of arterioles of ischemic muscles. However, engrafted cells did not differentiate into endothelial or smooth muscle cells. Limb perfusion normalized 4 weeks after cell injection. Inhibition of SDF-1 reduced the engraftment of transplanted cells and decreased endothelial cell proliferation. These findings suggest a two-stage model whereby transplanted MDPCs modulate wound repair through recruitment of inflammatory cells to ischemic tissue. This is an important potential mechanism for cell transplantation, in addition to the direct modulation of local vascular cells through paracrine mechanisms. | Andrew Wragg Jason A.Mellad Leilani E.Beltran Mikhail Konoplyannikov Hong San Sherry Boozer Robert J.Deans Anthony Mathur Robert J.Lederman Jason C.Kovacic Manfred Boehm | 2015 | 世界最新医学信息文摘2015，15，A0： | 0 |
| 10 | VEGFR1/CXCR4-positive progenitor cells modulate local inflammation and augment tissue perfusion by a SDF-1-dependent mechanism显示文摘Recruitment and retention of circulating progenitor cells at the site of injured or ischemic tissues facilitates adult neovascularization. We hypothesized that cell therapy could modulate local neo-vascularization through the vascular endothelial growth factor(VEGF)/stromal cellderived factor-1(SDF-1) axis and by paracrine effects on local endothelial cells. We isolated from rat bone marrow a subset of multipotent adult progenitor cell-derived progenitor cells(MDPC). In vitro, MDPCs secreted multiple cytokines related to inflammation and angiogenesis, including monocyte chemotactic protein-1, SDF-1, basic fibroblast growth factor, and VEGF, and expressed the chemokine receptors CXCR4 and VEGFR1. To investigate in vivo properties, we transplanted MDPCs into the ischemic hind limbs of rats. Elevated levels of the chemokine SDF-1 and colocalization of cd11b+ cells marked the initial phase of tissue remodeling after cell transplantation. Prolonged engraftment was observed in the adventitial–medial border region of arterioles of ischemic muscles. However, engrafted cells did not differentiate into endothelial or smooth muscle cells. Limb perfusion normalized 4 weeks after cell injection. Inhibition of SDF-1 reduced the engraftment of transplanted cells and decreased endothelial cell proliferation. These findings suggest a two-stage model whereby transplanted MDPCs modulate wound repair through recruitment of inflammatory cells to ischemic tissue. This is an important potential mechanism for cell transplantation, in addition to the direct modulation of local vascular cells through paracrine mechanisms. | Andrew Wragg Jason A.Mellad Leilani E.Beltran Mikhail Konoplyannikov Hong San Sherry Boozer Robert J.deans Anthony Mathur Robert J.lederman Jason C.Kovacic Manfred Boehm | 2015 | 世界最新医学信息文摘2015，15，90： | 0 |
| 11 | VEGFR1/CXCR4-positive progenitor cells modulate local inflammation and augment tissue perfusion by a SDF-1-dependent mechanism显示文摘Recruitment and retention of circulating progenitor cells at the site of injured or ischemic tissues facilitates adult neovascularization.We hypothesized that cell therapy could modulate local neo-vascularization through the vascular endothelial growth factor(VEGF)/stromal cellderived factor-1(SDF-1) axis and by paracrine effects on local endothelial cells.We isolated from rat bone marrow a subset of multipotent adult progenitor cell-derived progenitor cells(MDPC).In vitro,MDPCs secreted multiple cytokines related to inflammation and angiogenesis,including monocyte chemotactic protein-1,SDF-1,basic fibroblast growth factor,and VEGF,and expressed the chemokine receptors CXCR4 and VEGFR1.To investigate in vivo properties,we transplanted MDPCs into the ischemic hind limbs of rats.Elevated levels of the chemokine SDF-1 and colocalization of CD 11b^+ cells marked the initial phase of tissue remodeling after cell transplantation.Prolonged engraftment was observed in the adventitial-medial border region of arterioles of ischemic muscles.However,engrafted cells did not differentiate into endothelial or smooth muscle cells.Limb perfusion normalized 4 weeks after cell injection.Inhibition of SDF-1 reduced the engraftment of transplanted cells and decreased endothelial cell proliferation.These findings suggest a two-stage model whereby transplanted MDPCs modulate wound repair through recruitment of inflammatory cells to ischemic tissue.This is an important potential mechanism for cell transplantation,in addition to the direct modulation of local vascular cells through paracrine mechanisms. | Andrew Wragg Jason A.Mellad Leilani E.Beltran Mikhail Konoplyannikov Hong San Sherry Boozer robert J.deans anthony Mathur Robert J.lederman Jason C.Kovacic Manfred Boehm | 2016 | 世界最新医学信息文摘2016，16，4： | 0 |
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