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| 1 | Enhanced perovskite electronic properties via A-site cation engineering显示文摘Organic-inorganic halide perovskites have emerged as excellent candidates for low-cost photovoltaics and optoelectronics.While the predominant recent trend in designing perovskites for efficient and stable solar cells has been to mix different A-site cations,the role of A-site cations is still limited to tune the lattice and bandgap of perovskites.Herein we compare the optoelectronic properties of acetamidinum(Ace)and guanidinium(Gua)mixed methylammonium lead iodide perovskites and shed a light on the hidden role of A-site cation on the carrier mobility of mixed-cation lead iodide perovskites.The cations do not affect the bandgap of the perovskites since the orbitals from Ace and Gua do not contribute to the band edges of the material.However,the mobility of the Ace mixed perovskite is significantly enhanced to be an order of magnitude higher than that of the pristine perovskite.We apply the Ace mixed perovskite in hole-conductor-free printable mesoscopic perovskite solar cells and obtain a stabilized PCE of over 18%(certified 17.7%),which is the highest certified efficiency so far. | Xufeng Xiao Yanmeng Chu Chunyu Zhang Zhihui Zhang Zexiong Qiu Cheng Qiu Huaixing Wang Anyi Mei Yaoguang Rong Gengzhao Xu Yue Hu Hongwei Han | 2021 | Fundamental Research2021，1，4： | 2 |
| 2 | A Case of Refractory Childhood Glaucoma Secondary to Weill-Marchesani Syndrome:Management with Combined CO_(2) Laser-Assisted Sclerectomy Surgery and Trabeculectomy显示文摘A 2-year-old girl was diagnosed as Weill-Marchesani syndrome with typical systemic features of short stature,short and stubby hands and feet,language disorders and mental retardation.He developed bilateral angle closure glaucoma,ectopia lentis and suffered visual loss from the ocular features of Weill-Marchesani syndrome.The child was successfully treated by combined CO_(2) laser-assisted sclerectomy surgery and trabeculectomy. | Yang Zhang Ailing Bian Anyi Liang Fei Mo Gangwei Cheng | 2022 | Chinese Medical Sciences Journal2022，37，2： | 1 |
| 3 | AHNAK2 is a biomarker and a potential therapeutic target of adenocarcinomas显示文摘Adenocarcinoma is the second largest histological type of cervical cancer,second only to cervical squamous cell carcinoma.At present,despite the clinical treatment strategies of cervical adenocarcinoma and cervical squamous cell carcinoma being similar,the outcome and prognosis of cervical adenocarcinoma are significantly poor.Therefore,it is urgent to find specific biomarker and therapeutic target for cervical adenocarcinoma.In this study,we aim to reveal and verify the potential biomarkers and therapeutic targets of cervical adenocarcinoma.Weighted correlation network analysis(WGCNA)reveals the differentially-expressed genes significantly related to the histological characteristics of the two cervical cancer subtypes.We select the genes with the top 20 significance for further investigation.Through microarray and immunohistochemical(IHC)analyses of a variety of tumor tissues,we find that among these 20 genes,AHNAK2 is highly expressed not only in cervical adenocarcinoma,but also in multiple of adenocarcinoma tissues,including esophagus,breast and colon,while not in normal gland tissues.In vitro,AHNAK2 knockdown significantly inhibits cell proliferation and migration of adenocarcinoma cell lines.In vivo,AHNAK2 knockdown significantly inhibits tumor progression and metastasis of various adenocarcinomas.RNA-sequencing and bioinformatics analyses suggest that the inhibitory effect of AHNAK2 knockdown on tumor progression is achieved by regulating DNA replication and upregulating Bim expression.Together,we demonstrate that AHNAK2 is a biomarker and a potential therapeutic target for adenocarcinomas. | Meng Xu Anyi Cheng Liya Yu Wei Wei Jinpeng Li Cheguo Cai | 2022 | Acta Biochimica et Biophysica Sinica2022，54，11： | 0 |
| 4 | Comprehensive reutilization of herbal waste:Coproduction of magnolol,honokiol,and β-amyrin from Magnolia officinalis residue显示文摘Herbal extraction residues(HERs)cause serious environmental pollution and resource waste.In this study,a novel green route was designed for the comprehensive reutilization of all components in HERs,taking Magnolia officinalis residues(MOR)as an example.The reluctant structure of MOR was first destroyed by alkali pretreatment to release the functional ingredients(magnolol and honokiol)originally remaining in MOR and to make MOR more accessible for hydrolysis.A metal–organic frame material MIL-101(Cr)with a maximum absorption capacity of 255.64 mg g^(-1)was synthesized to absorb the released honokiol and magnolol from the pretreated MOR solutions,and 40 g L^(-1)reducing sugars were obtained with 81.8%enzymatic hydrolysis rate at 10%MOR solid loading.Finally,382 mg L-1β-amyrin was produced from MOR hydrolysates by an engineered yeast strain.In total,1 kg honokiol,8 kg magnolol,and 7.64 kg β-amyrin could produce from 1 ton MOR by this cleaner process with a total economic output of 170,700 RMB. | Lukun Xiao Anyi Zhao Jie Qiu An Liu Sha Chen Jinzhu Jiang Jun Zhang Cong Guo Jipeng Di Jintang Cheng Chang Chen Kangxin Hou Aiping Zhang Yan Liu Caixia Wang | 2024 | Green Energy & Environment2024，9，2： | 0 |
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