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| 1 | Stable classi?cation with limited sample: transferring a 30-m resolution sample set collected in 2015 to mapping 10-m resolution global land cover in 2017显示文摘As the world strives to reduce the impact of population growth, urbanization, agricultural expansion, and climate change on food security, energy and water shortage, resource over-exploration, biodiversity loss, environmental pollution, and ultimately human health, timely and higher resolution land cover information is urgently needed to achieve the sustainable development goals of the United Nations. | Peng Gong Han Liu Meinan Zhang Congcong Li Jie Wang Huabing Huang Nicholas Clinton Luyan Ji Wenyu Li Yuqi Bai Bin Chen Bing Xu Zhiliang Zhu Cui Yuan Hoi Ping Suen Jing Guo Nan Xu Weijia Li Yuanyuan Zhao Jun Yang Chaoqing Yu Xi Wang Haohuan Fu Le Yu Iryna Dronova Fengming Hui Xiao Cheng Xueli Shi Fengjin Xiao Qiufeng Liu Lianchun Song | 2019 | Science Bulletin2019，64，6： | 166 |
| 2 | Research progress on silicon/carbon composite anode materials for lithium-ion battery显示文摘Silicon(Si) has been considered as one of the most promising anode material for the next generation lithium-ion batteries(LIBs) with high energy densities, due to its high theoretical capacity, abundant availability and environmental friendliness. However, silicon materials with low intrinsic electric and ionic conductivity suffer from huge volume variation during lithiation/delithiation processes leading to the pulverization of Si and subsequently resulting in severe capacity fading of the electrodes. Coupling of Si with carbon(C) realizes a favorable combination of the two materials properties, such as high lithiation capacity of Si and excellent mechanical and conductive properties of C, making silicon/carbon composite(Si/C) ideal candidates for LIBs anodes. In this review, recent progresses of Si/C materials utilized in LIBs are summarized in terms of structural design principles, material synthesis methods, morphological characteristics and electrochemical performances by highlighting the material structures. The mechanisms behind the performance enhancement are also discussed. Moreover, other factors that affect the performance of Si/C anodes, such as prelithiation, electrolyte additives, and binders, are also discussed. We aim to present a full scope of the Si/C-based anodes, and help understand and design future structures of Si/C anodes in LIBs. | Xiaohui Shen Zhanyuan Tian Ruijuan Fan Le Shao Dapeng Zhang Guolin Cao Liang Kou Yangzhi Bai | 2018 | Journal of Energy Chemistry2018，27，4： | 29 |
| 3 | Expenditure and financial burden for the diagnosis and treatment of colorectal cancer in China:a hospital.based,multicenter,cross-sectional survey显示文摘Background: The increasing prevalence of colorectal cancer(CRC) in China and the paucity of information about relevant expenditure highlight the necessity of better understanding the financial burden and effect of CRC diagnosis and treatment. We performed a survey to quantify the direct medical and non-medical expenditure as well as the resulting financial burden of CRC patients in China.Methods: We conducted a multicenter, cross-sectional survey in 37 tertiary hospitals in 13 provinces across China between 2012 and 2014. Each enrolled patient was interviewed using a structured questionnaire. All expenditure data were inflated to the 2014 Chinese Yuan(CNY; 1 CNY = 0.163 USD). We quantified the overall expenditure and financial burden and by subgroup(hospital type, age at diagnosis, sex, education, occupation, insurance type, household income, clinical stage, pathologic type, and therapeutic regimen). We then performed generalized linear modeling to determine the factors associated with overall expenditure.Results: A total of 2356 patients with a mean age of 57.4 years were included, 57.1 % of whom were men; 13.9% of patients had stage I cancer; and the average previous-year household income was 54,525 CNY.The overall average direct expenditure per patient was estimated to be 67,408 CNY, and the expenditures for stage Ⅰ, Ⅱ, Ⅲ, and Ⅳ disease were 56,099 CNY, 59,952 CNY, 67,292 CNY, and 82,729 CNY, respectively. Non-medical expenditure accounted for 8.3%of the overall expenditure. The 1-year out-of-pocket expenditure of a newly diagnosed patient was 32,649 CNY, which accounted for 59.9% of their previous-year household income and caused 75.0% of families to suffer an unmanageable financial burden. Univariate analysis showed that financial burden and overall expenditure differed in almost all subgroups(P < 0.05), except for sex. Multivariate analysis showed that patients who were treated in specialized hospitals and those who were diagnosed with adenocarcinoma or diagnosed at a later stage were likely to spend more,whereas those with a lower household income and those who underwent surgery spent less(all P < 0.05).Conclusions: For patients in China, direct expenditure for the diagnosis and treatment of CRC seemed catastrophic,and non-medical expenditure was non-ignorable. The financial burden varied among subgroups, especially among patients with different clinical stages of disease, which suggests that, in China, CRC screening might be cost-effective. | Hui-Yao Huang Ju-Fang Shi Lan-Wei Guo Ya-Na Bai Xian-Zhen Liao Guo-iangLiu A-Yan Mao Jian-Song Ren Xiao-Jie Sun Xin-Yu Zhu Le Wang Bing-Bing Song Ling-Bin Du Lin Zhu Ji-Yong Gong Qi Zhou Yu-Qin Liu Rong Cao Ling Mai Li Lan Xiao-Hua Sun Ying Ren Jin-Yi Zhou Yuan-Zheng Wang Xiao Qi Pei-An Lou Dian Shi Ni Li Kai Zhang Jie He Min Dai | 2017 | Chinese Journal of Cancer2017，36，8： | 25 |
| 4 | Onco-miR-24 regulates cell growth and apoptosis by targeting BCL2L11 in gastric cancer显示文摘胃的癌症是世界范围的最普通的恶意之一;然而,在 tumorigenesis 的分子的机制仍然需要探索。BCL2L11 属于 BCL-2 家庭,并且充当内在的 apoptotic 串联的一个中央管理者并且调停房间 apoptosis。尽管 miRNAs 被报导了涉及癌症开发的每个阶段,在 GC 的 miR-24 的角色还没被报导。在现在的学习,当 BCL2L11 的表示在 GC 的肿瘤纸巾被禁止时, miR-24 被发现起来调整。研究从在 vitro 并且在显示出的 vivo,那 miR-24 调整 BCL2L11 表示由与 mRNA 的 3UTR 直接有约束力,因此支持房间生长,移植当禁止房间 apoptosis 时。因此, miR-24 是能是为未来的潜在的药目标的新奇 onco-miRNA 临床的使用。 | Haiyang Zhang Jingjing Duan Yanjun Qu Ting Deng Rui Liu Le Zhang Ming Bai Jialu Li Tao Ning Shaohua Ge Xia Wang ZhenzhenWang~ Qian Fan Hongli Li Guoguang Ying Dingzhi Huang Yi Ba | 2016 | Protein & Cell2016，7，2： | 11 |
| 5 | Mechanical Properties and Microstructure of In Situ TiB_2-7055 Composites显示文摘In order to fabricate a kind of high strength particulate reinforced aluminum-matrix composites, the high strength aluminum alloy 7055 was selected as a matrix. Composites reinforced with varying amounts of TiB2 particles were synthesized using the in situ method, and their mechanical properties and microstructure were analyzed. It is found that the in situ TiB2 particles sized from 50 to 400 nm uniformly disperse in the matrix. With the weight fraction of TiB2 particles increasing, the elastic modulus as well as the yield strength and the ultimate tensile strength increase, while the ductility decrease. The improvement of strength could be attributed to good bonding between TiB2 and the matrix, and also the TiB2 particles act as a barrier to dislocation. | CHEN dong LE Yong-kang BAI Liang MA Nai-heng LI Xian-feng WANG Hao-wei | 2006 | Chinese Journal of Aeronautics2006，19，B12： | 8 |
| 6 | Assessment of the cropland classifications in four global land cover datasets: A case study of Shaanxi Province, China显示文摘Accurate and reliable cropland surface information is of vital importance for agricultural planning and food security monitoring. As several global land cover datasets have been independently released,an inter-comparison of these data products on the classification of cropland is highly needed. This paper presents an assessment of cropland classifications in four global land cover datasets,i.e.,moderate resolution imaging spectrometer(MODIS) land cover product,global land cover map of 2009(Glob Cover2009),finer resolution observation and monitoring of global cropland(FROM-GC) and 30-m global land cover dataset(Globe Land30). The temporal coverage of these four datasets are circa 2010. One of the typical agricultural regions of China,Shaanxi Province,was selected as the study area. The assessment proceeded from three aspects: accuracy,spatial agreement and absolute area. In accuracy assessment,506 validation samples,which consist of 168 cropland samples and 338 non-cropland ones,were automatically and systematically selected,and manually interpreted by referencing high-resolution images dated from 2009 to 2011 on Google Earth. The results show that the overall accuracy(OA) of four datasets ranges from 61.26 to 80.63%. Globe Land30 dataset,with the highest accuracy,is the most accurate dataset for cropland classification. The cropland spatial agreement(mainly located in the plain ecotope of Shaanxi) and the non-cropland spatial agreement(sparsely distributed in the south and middle of Shaanxi) of the four datasets only makes up 33.96% of the whole province. FROM-GC and Globe Land30,obtaining the highest spatial agreement index of 62.40%,have the highest degree of spatial consistency. In terms of the absolute area,MODIS underestimates the cropland area,while Glob Cover2009 significantly overestimates it. These findings are of value in revealing to which extent and on which aspect that these global land cover datasets may agree with each other at small scale on each ecotope region. The approaches taken in this study could be used to derive a fused cropland classification dataset. | CHEN Xiao-yu LIN Ya ZHANG Min YU Le LI Hao-chuan BAI Yu-qi | 2017 | Journal of Integrative Agriculture2017，16，2： | 8 |
| 7 | Six new monacolin analogs from red yeast rice显示文摘Six novel monacolin analogs, monacolins V_1–V_6(1–6), together with seven known ones(7–13), were isolated from the ethyl acetate extract of red yeast rice. Their structures and absolute configurations were determined by spectroscopic methods,especially 2D NMR(~1H-~1HCOSY, HSQC, HMBC, and NOESY/ROESY) and CD spectroscopic analyses as well as chemical derivation.Monacolins V_2(2) and V_3(3) represent the first examples of monacolins with 3-hydroxybutyrate substitute. The anti-inflammatory inhibitory activities against the lipopolysaccharide(LPS) induced NO production in BV-2 cells as well as antioxidant activities against rat liver microsomal lipid peroxidation were evaluated. | LIU Bing-Yu XU Fei BAI Jian YAN Dao-Jiang ZHANG Le ZHANG Dan HU You-Cai | 2019 | Chinese Journal of Natural Medicines2019，17，5： | 3 |
| 8 | Selection of water source for water transfer based on algal growth potential to prevent algal blooms显示文摘Water transfer is becoming a popular method for solving the problems of water quality deterioration and water level drawdown in lakes. However, the principle of choosing water sources for water transfer projects has mainly been based on the effects on water quality, which neglects the influence in the variation of phytoplankton community and the risk of algal blooms. In this study, algal growth potential(AGP) test was applied to predict changes in the phytoplankton community caused by water transfer projects. The feasibility of proposed water transfer sources(Baqing River and Jinsha River) was assessed through the changes in both water quality and phytoplankton community in Chenghai Lake, Southwest China. The results showed that the concentration of total nitrogen(TN) and total phosphorus(TP) in Chenghai Lake could be decreased to 0.52 mg/L and 0.02 mg/L respectively with the simulated water transfer source of Jinsha River. The algal cell density could be reduced by 60%, and the phytoplankton community would become relatively stable with the Jinsha River water transfer project, and the dominant species of Anabaena cylindrica evolved into Anabaenopsis arnoldii due to the species competition. However, the risk of algal blooms would be increased after the Baqing River water transfer project even with the improved water quality. Algae gained faster proliferation with the same dominant species in water transfer source. Therefore, water transfer projects should be assessed from not only the variation of water quality but also the risk of algal blooms. | Yongjun Song Jing Qi Le Deng Yaohui Bai Huijuan Liu Jiuhui Qu | 2021 | Journal of Environmental Sciences2021，33，5： | 3 |
| 9 | Optical visualization and polarized light absorption of the single-wall carbon nanotube to verify intrinsic thermal applications显示文摘The predicted extraordinary properties of carbon nanotubes(CNTs)from theoretical calculations have great potential for many applications.However,reliable experimental determination of intrinsic properties at the single-tube level is currently a matter of concern,and many challenges remain because of the unhandled and nanoscale size of individual nanotubes.Here,we demonstrated a prototype to detect the intrinsic thermal conductivity of the single-wall carbon nanotube(SWCNT)and verify the significant non-resonant optical absorption behavior on tiny nanotubes by integrating the nanotube and ice into a new core-shell design.In particular,a reversible optical visualization method based on the individual suspended ultra-long SWCNT was first developed by wrapping a nanotube with ice in the cryogenic air environment.The light-induced thermal effect on the hybrid core-shell structure was used tomelt the ice shell,which subsequently acted as a temperature sensor to verify the intrinsic thermal conductivity of the core-like nanotube.More interestingly,we successfully determined for the first time the thermal response phenomenon of the tiny absorption cross section in SWCNT in the vertical-polarization configuration and the significant non-resonant absorption behavior in the parallel-polarization configuration.These investigations will provide a better understanding for the unique optical behaviors of CNT and enable the detection of intrinsic properties of various one-dimensional nanostructures such as nanotubes,nanowires,and nanoribbons. | Xiao Zhang Li Song Le Cai Xuezeng Tian Qiang Zhang Xiaoying Qi Wenbin Zhou Nan Zhang Feng Yang Qingxia Fan Yanchun Wang Huaping Liu Xuedong Bai Weiya Zhou Sishen Xie | 2015 | Light(Science & Applications)2015，4，1： | 2 |
| 10 | Atomically isolated Pd sites within Pd-S nanocrystals enable trifunctional catalysis for direct,electrocatalytic and photocatalytic syntheses of H_(2)O_(2)显示文摘Although high-efficiency production of hydrogen peroxide(H_(2)O_(2))can be realized separately by means of direct,electrochemical,and photocatalytic synthesis,developing versatile catalysts is particularly challenging yet desirable.Herein,for the first time we reported that palladium-sulphur nanocrystals(Pd-S NCs)can be adopted as robust and universal catalysts,which can realize the efficient O_(2) conversion by three methods.As a result,Pd-S NCs exhibit an excellent selectivity(89.5%)to H_(2)O_(2)with high productivity(133.6 mol·kgcat^(−1)·h^(−1))in the direct synthesis,along with the significantly enhanced H_(2)O_(2)production activity and stability via electrocatalytic and photocatalytic syntheses.It is demonstrated that the isolated Pd sites can enhance the adsorption of O_(2) and inhibit its O–O bond dissociation,improving H_(2)O_(2)selectivity and reducing H_(2)O_(2)degradation.Further study confirms that the difference in surface atom composition and arrangement is the key factor for different ORR mechanisms on Pd NCs and Pd-S NCs. | Tang Yang Chengyong Yang Jiabo Le Zhiyong Yu Lingzheng Bu Leigang Li Shuxing Bai Qi Shao Zhiwei Hu Chih-Wen Pao Jun Cheng Yonggang Feng Xiaoqing Huang | 2022 | Nano Research2022，15，3： | 2 |
| 11 | AoATG5 plays pleiotropic roles in vegetative growth,cell nucleus development,conidiation,and virulence in the nematode-trapping fungus Arthrobotrys oligospora显示文摘Autophagy is an evolutionarily conserved process in eukaryotes,which is regulated by autophagy-related genes(ATGs).Arthrobotrys oligospora is a representative species of nematode-trapping(NT)fungi that can produce special traps for nematode predation.To elucidate the biological roles of autophagy in NT fungi,we characterized an orthologous Atg protein,AoAtg5,in A.oligospora.We found that AoATG5 deletion causes a significant reduction in vegetative growth and conidiation,and that the transcript levels of several sporulation-related genes were significantly downregulated during sporulation stage.In addition,the cell nuclei were significantly reduced in theΔAoATG5 mutant,and the transcripts of several genes involved in DNA bio-synthesis,repair,and ligation were significantly upregulated.InΔAoATG5 mutants,the autophagic process was significantly impaired,and trap formation and nematocidal activity were significantly decreased.Comparative transcriptome analysis results showed that AoAtg5 is involved in the regulation of multiple cellular processes,such as autophagy,nitrogen metabolism,DNA biosynthesis and repair,and vesicular transport.In summary,our results suggest that AoAtg5 is essential for autophagy and significantly contributes to vegetative growth,cell nucleus development,sporulation,trap formation,and pathogenicity in A.oligospora,thus providing a basis for future studies focusing on related mechanisms of autophagy in NT fungi. | Duanxu Zhou Yingmei Zhu Na Bai Le Yang Meihua Xie Jiangliu Yang Meichen Zhu Ke-Qin Zhang Jinkui Yang | 2022 | Science China(Life Sciences)2022，65，2： | 2 |
| 12 | Spinosin, a C-glycoside flavonoid from semen Zizhiphi Spinozae, potentiated pentobarbital-induced sleep via the serotonergic system 显示文摘 | Wang LE Bai YJ Shi XR | 2008 | Pharmacol Biochem Be2008，90，3： | 1 |
| 13 | Adaptive interference alignment with CSI uncertainty 显示文摘 | Xie Bai Le Li Yang Minn H | 2013 | IEEE Transactions on Communications2013，61，2： | 1 |
| 14 | PKC-SWI6 signaling regulates asexual development,cell wall integrity,stress response,and lifestyle transition in the nematode-trapping fungus Arthrobotrys oligospora显示文摘Predatory fungi possess intricate signal transduction systems that regulate their development and support successful infection of the host.Herein,we characterized three components of the cell wall integrity-controlling pathway,namely protein kinase C(Ao PKC),SLT2-MAPK(Ao SLT2),and SWI6(Ao SWI6),in a representative nematode-trapping fungus Arthrobotrys oligospora,using gene disruption and multi-omics approaches.The phenotypic traits(such as mycelia development,conidiation,stress response,and trap morphogenesis) and metabolic profiles of ΔAopkc and ΔAoswi6 mutants were similar but differed from those of the ΔAoslt2 mutants.Transcriptomic analysis indicated that the genes differentially expressed in the absence of Aoswi6 were involved in DNA replication,repair,and recombination during trap formation.Moreover,the yeast two-hybrid assay showed that Ao PKC interacted with Ao SWI6,suggesting that in A.oligospora,PKC can directly regulate SWI6,bypassing the SLT2signaling cascade.Conclusively,our findings deepen our understanding of the regulatory mechanism of asexual development and lifestyle switching in nematode-trapping fungi. | Meihua Xie Ni Ma Na Bai Le Yang Xuewei Yang Ke-Qin Zhang Jinkui Yang | 2022 | Science China(Life Sciences)2022，65，12： | 1 |
| 15 | Spinosin,a C-glycosied flavonoid from semen Zizhiphi Spinozae,potentiated pentobarbital-in-duced sleep via the serotonergic system显示文摘 | Wang LE Bai YJ Shi XR | 2008 | Pharmacol Biochem Be2008，90，3： | 1 |
| 16 | N-heterocyclic carbene-stabilized metal nanoparticles within porous organic cages for catalytic application显示文摘Tuning the surface-embellishing ligands of metal nanoparticles(NPs) is a powerful strategy to modulate their morphology and surface electronic and functional features, impacting their catalytic activity and selectivity. In this work, we report the design and synthesis of a polytriazolium organic cage PIC-T, capable of stabilizing Pd NPs within its discrete cavity. The obtained material(denoted Pd@PCC-T) is highly durable and monodispersed with narrow particle-size distribution of 2.06 ± 0.02 nm, exhibiting excellent catalytic performance and recyclability in the Sonogashira coupling and tandem reaction to synthesize benzofuran derivatives. Further investigation indicates that the modulation of N-heterocyclic carbene sites embedded in the organic cage has an impact on NPs’ catalytic efficiency, thus providing a novel methodology to design superior NP catalysts. | Tong Liu Sha Bai Le Zhang F.Ekkehardt Hahn Ying-Feng Han | 2022 | National Science Review2022，9，6： | 1 |
| 17 | Gold nanoparticles supported on function- alized mesoporous silica for selective oxidation of cyclohexane显示文摘 | Wu P P Bai P Le Z B | 2011 | Mieroporous and Mesoporous Materials2011，141，3： | 1 |
| 18 | Spinosin,a C-glycoside flavonoid from semen Zizhiphi Spinozae,potentiated pentobarbital-induced sleep via the serotonergic system显示文摘 | Wang LE Bai YJ Shi XR | 2008 | Pharmacol Biochem Behav2008，90，3： | 1 |
| 19 | Spinosin, a C - glycoside flavonoidfrom Semen Zizyphi Spinosae, potentiated pentobarbital - inducedsleep via the serotonergic system 显示文摘 | Wang LE Bai YJ Shi XR | 2008 | Pharmacol Biochem Behav2008，90，3： | 1 |
| 20 | Spinosin,a C-glycoside flavonoidfrom semen Zizhiphi Spinozae,potentiated pentobarbital-induced sleepvia the serotonergic system显示文摘 | Wang LE Bai YJ Shi XR | 2008 | Pharmacology Biochemistry and Be-havior2008，90，： | 1 |
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