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| 1 | The role of m6A modification in the biological functions and diseases显示文摘N6-methyladenosine(m6A)is the most prevalent,abundant and conserved internal cotranscriptional modification in eukaryotic RNAs,especially within higher eukaryotic cells.m6A modification is modified by the m6A methyltransferases,or writers,such as METTL3/14/16,RBM15/15B,ZC3H3,VIRMA,CBLL1,WTAP,and KIAA1429,and,removed by the demethylases,or erasers,including FTO and ALKBH5.It is recognized by m6A-binding proteins YTHDF1/2/3,YTHDC1/2 IGF2BP1/2/3 and HNRNPA2B1,also known as'readers'.Recent studies have shown that m6A RNA modification plays essential role in both physiological and pathological conditions,especially in the initiation and progression of different types of human cancers.In this review,we discuss how m6A RNA methylation influences both the physiological and pathological progressions of hematopoietic,central nervous and reproductive systems.We will mainly focus on recent progress in identifying the biological functions and the underlying molecular mechanisms of m6A RNA methylation,its regulators and downstream target genes,during cancer progression in above systems.We propose that m6A RNA methylation process offer potential targets for cancer therapy in the future. | Xiulin Jiang Baiyang Liu Zhi Nie Lincan Duan Qiuxia Xiong Zhixian Jin Cuiping Yang Yongbin Chen | 2021 | Signal Transduction and Targeted Therapy2021，6，3： | 16 |
| 2 | Nitriding of Hard Fe Electrodepositionand Its Effects on Wear Resistance显示文摘Nitriding is employed for the hard Fe electrodeposition to produce a hard-facing and antiwear coating. It only takes 1 h for the hard Fe coating, which is much shorter than nitriding the Fe and steel. The results showed that the nitriding can increase the microhardness, wear resistance of the coating, as well as the bonding strength of the coating with the substrate. Additionally it can eliminate the brittleness, turn the internal stress of the coating from tension to compression. The wear resistance of the nitrided Fe coating is 4.6 times as high as that of Cr coating. It is simple and economic to combine hard be electroplating and nitriding, which is a good technology of the tribological surface modification. | Chenghui GAO, Dajian CHEN and Baiyang ZHOU Department of Mechanical Engineering, Fuzhou University, Fujian, Fuzhou 350002, China | 2001 | Journal of Materials Science & Technology2001，17，2： | 5 |
| 3 | Effects of the Composition of Electrodeposited Fe-Ni-P Alloy on the Thermostability and Magnetic Properties显示文摘The magnetic properties, structure defects of electrodeposited Fe-Ni-P alloys with various compositions and the thermostability at amorphous state have been studied by DSC, positron annihilation and electronic integrating instrument methods. The results show that the thermostability of amorphous Fe-Ni-P alloys increases with Fe content. Emergence and recrystallization of stable phases defer as the P content of the coating increases. The minimum Hc, Br and Ph occur at 9.4 P (wt pct) content. Maximum Hc, Br and Ph occur at the weight ratio of Fe to Ni equaling to 1/9. | Chenghui GAO Baiyang ZHOU (Institute for Materials Research, Fuzhou University, Fuzhou 350002, China)(Manuscript received February 22, 1996, in revised form June 3, 1996) | 1997 | Journal of Materials Science & Technology1997，13，2： | 4 |
| 4 | 印度和西北太平洋夏季风在年际变化强度和季风-ENSO准两年关系方面的对比显示文摘印度夏季风和西北太平洋夏季风是亚洲季风系统的重要组成部分,研究这两个季风的变异规律具有重要的科学和现实意义。我们在研究中发现热带大西洋海温的影响在最近年代的显著增强可以激发印度和西北太平洋夏季风之间的‘跷跷板’现象,引起这两个季风在年际变化强度和季风–ENSO准两年关系方面的年代际反位相变化。在80年代中期之后(之前),ENSO和热带大西洋(热带印度洋)海表面温度具有更强的耦合,从而支持西北太平洋夏季风(印度夏季风)可以表现出更强的年际变化强度和季风–ENSO准两年关系。在预测未来的亚洲夏季风变化时,热带大西洋海温的影响可能需要给予更多的考虑。 | CHEN Baiyang WANG Lei WU Minmin | 2020 | Atmospheric and Oceanic Science Letters2020，13，5： | 3 |
| 5 | Study of polluted soil remediation based on freezing and thawing cycles显示文摘It is generally known that soil pollution poses a terrible hazard to the environment, but the present techniques of contaminated soil remediation cannot control this growing threat. This paper compares the pollutant extraction efficiency of traditional pumping and treating, which is a typical washing technology for the remediation of contaminated soils, with methods that utilize freeze-thaw cycles. In the soil freezing process, water shifts from unfrozen soils to the freezing front, and the permeability of soil will be enhanced under certain temperature gradients and water conditions. Therefore, this paper discusses the purification of contaminated soil through freeze-thaw action. We conducted a cleansing experiment on clay and silica sand infused with NaCl(simulation of heavy metals) and found that the efficiency of purification was enhanced remarkably in the latter by the freeze-thaw action. To assess the effective extraction of DNAPLs in soil, we conducted an experiment on suction by freezing, predicated on the different freezing points of moisture and pollutants. We found that the permeability coefficient was significantly increased by the freezing-thawing action, enabling the DNAPL contaminants to be extracted selectively and effectively. | DaHu Rui BaiYang Song Yuzuru Ito Li Wang | 2014 | Research in Cold and Arid Regions2014，6，4： | 3 |
| 6 | Overview to the Hard X-ray Modulation Telescope (Insight-HXMT) Satellite显示文摘As China’s first X-ray astronomical satellite, the Hard X-ray Modulation Telescope (HXMT), which was dubbed as Insight-HXMT after the launch on June 15, 2017, is a wide-band(1-250 ke V) slat-collimator-based X-ray astronomy satellite with the capability of all-sky monitoring in 0.2-3 Me V. It was designed to perform pointing, scanning and gamma-ray burst(GRB)observations and, based on the Direct Demodulation Method (DDM), the image of the scanned sky region can be reconstructed.Here we give an overview of the mission and its progresses, including payload, core sciences, ground calibration/facility, ground segment, data archive, software, in-orbit performance, calibration, background model, observations and some preliminary results. | Shuang-Nan Zhang TiPei Li FangJun Lu LiMing Song YuPeng X u CongZhan Liu Yong Chen XueLei Cao QingCui Bu Zhi Chang Gang Chen Li Chen TianXiang Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong Yuan Yuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan Can Gungor ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge Ou JinLu Qu Na Sai RenCheng Shang GuoHong Shen Liang Sun Ying Tan Lian Tao YouLi Tuo Chen Wang ChunQin Wang GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BaiYang Wu BoBing Wu Mei Wu GuangCheng Xiao ShaoLin Xiong LinLi Yan JiaWei Yang Sheng Yang YanJi Yang QiBin Yi Bin Yuan AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang ShenYi Zhangs Shu Zhang Tong Zhang WanChang Zhang Wei Zhang WenZhao Zhang Yi Zhang YiFei Zhang YongJie Zhang Yue Zhang Zhao Zhang Zhi Zhang ZiLiang Zhang HaiSheng Zhao XiaoFan Zhao ShiJie Zheng JianFeng Zhou YuXuan Zhu Yue Zhu RenLin Zhuang | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，4： | 2 |
| 7 | The mitochondrial function was impaired in APP knockout mouse embryo fibroblast cells显示文摘The amyloid precursor protein (APP) is recognized as the source of Aβ, which plays an important role in Alzheimer’s disease. However, the biological function of APP is obscure. Previous studies showed that mitochondria could be a target of APP. In this work, APP knockout mouse embryo fibroblast (MEF) cells were used to test if APP plays any role in maintaining the mitochondrial function. As the result, APP knockout MEF cells (APP-/- cells) showed the abnormal mitochondrial function, including slower cell proliferation, lower mitochondrial membrane potential, lower intracellular ROS, higher mitochondrial membrane fluidity and lower cytochrome c oxidase activity than their wild-type counterparts. However, no change was found in the amount of mitochondria in MEF APP-/-cells. | SHENG BaiYang NIU Ying ZHOU Hui ZHOU Hui YAN JiaXin ZHAO NanMing ZHANG XiuFang GONG YanDao | 2009 | Chinese Science Bulletin2009，54，10： | 2 |
| 8 | Expression of a late em- bryogenesis abundant protein genv, HVa1, from barley confers toler- ance to water deficit and salt stress in transgenic rice 显示文摘 | Deping Xu Xiaolan Duan Baiyang | 1996 | Plant Physiology1996，110，： | 1 |
| 9 | Effects of ozone and ozone/peroxide pretreatments on disinfection byproduct formation during subsequent chlorination and chloramination 显示文摘 | Xin Yang Jinfeng Peng Baiyang Chen | 2012 | Journal of Hazardous Materials2012，，： | 1 |
| 10 | Prussian blue caged in spongiform adsorbents using diatomite and carbon nanotubes for elimina- tion of cesium显示文摘 | HU Baiyang BUNSHI F YU Hongwen | 2012 | Hazardous Materials2012，，： | 1 |
| 11 | A novel microRNA miR-MTCO3P38 inhibits malignant progression via STAT3/PTTG1/MYC in hepatocellular carcinoma显示文摘To the Editor,Hepatocellular carcinoma(HCC)is a malignant tumor with the fourth highest incidence and the third highest mortality among all tumor sites in China.1 Finding new diagnostic markers and therapeutic molecules may be of great value in the treatment of HCC and the improvement of prognosis. | Deliang Guo Yang Gu Dong Ma Pengpeng Liu Baiyang Chen Zhisu Liu Ping Wu Quanyan Liu | 2022 | Genes & Diseases2022，9，4： | 1 |
| 12 | Study on Corrosion Wear Behavior of 70 Aluminum Alloy Oxide Coating显示文摘 | LOU Baiyang ZHU Guo LI Peihua | 2013 | Advanced Ma- terials Research2013，625，： | 1 |
| 13 | Soot size distribution in lightly sooting premixed flames of benzene and toluene显示文摘The evolution of particle size distribution function(PSDF)of soot in premixed flames of benzene and toluene was studied on a burner stabilized stagnation(BSS)flame platform.The cold gas velocities were changed to hold the maximum flame temperatures of different flames approximately constant.The PSDFs of all the test flames exhibited a bimodal distribution,i.e.,a small-size nucleation mode and a large-size accumulation mode.It was observed that soot nucleation and particle growth in the benzene flame were stronger than those in the toluene flame at short residence times.At longer residence times,the PSDFs of the two flames were similar,and the toluene flame showed a larger particle size distribution range and a higher particle volume fraction than the benzene flame. | Wang LIU Jiaqi ZHAI Baiyang LIN He LIN Dong HAN | 2020 | Frontiers in Energy2020，14，1： | 1 |
| 14 | In-situ interaction of nano-PbS with gelatin显示文摘Water-soluble gelatin–PbS bionanocomposites(BNCs)were synthesized via a facile one-pot chemical reaction method at pH7.40.The samples were characterized by transmission electron microscopy(TEM),X-ray diffraction(XRD),UV-vis absorption spectra(UV-vis),Fourier transform infrared spectra(FT-IR)and circular dichroism(CD).FT-IR data were used to envisage the binding of PbS particles with oxygen atoms of carbonyl groups of gelatin molecule.The possible integration mechanism between gelatin and PbS was discussed in detail.The effect of Pb2+and PbS on the conformations of gelatin has also been analyzed by means of UV-vis,CD and FT-IR spectra,resulting in less-helix content and more open structures(-sheet,β-turn,or expanded).A new formula to calculate the association constant was proposed according to the relationship between the absorbance of gelatin–PbS BNCs and the free concentration of PbS,and apparent association constants K(298/303/308 K:3.11/2.00/1.60×106mol/L)at three different temperatures were calculated based on this formula.Thermodynamic parameters such asΔGθ,ΔHθ andΔSθ were also determined.The results of the thermodynamic investigations indicated that the reaction was spontaneous(ΔGθ<0),and enthalpy-driven(ΔHθ<0). | WANG Jun TANG ShiHua WANG BaiYang LI YouQun | 2013 | Science China Chemistry2013，56，11： | 1 |
| 15 | Prussian Blue Caged in Alginate/Calcium Beads as Adsorbents for Removal of Cesium Ions from Contami- nated Water显示文摘 | Vipin Adavan Kiliyankil Hu Baiyang Fugetsu Bun- shi | 2013 | J Hazard Mater2013，，： | 1 |
| 16 | Expression of a late embryogenesis abundant protein gene, HVAI, from barley conferred tolerance to water deficit and salt stress in transgenic rice 显示文摘 | Xu Deping Duan X iaolan Wang Baiyang | 1996 | Plant Physiol1996，110，： | 1 |
| 17 | miR-133b targets NCAPH to promote β-catenin degradation and reduce cancer stem cell maintenance in non-small cell lung cancer显示文摘Dear Editor,Non-small cell lung cancer(NSCLC),one of the most common lung cancers,is well known to have diverse pathological features.Cancer stem cells(CSCs)have been identified to play critical roles in tumor metastasis and drug resistance,while its potential clinical significance and molecular mechanism are still unclear.In addition,numerous findings have also shown that miRNAs play pivotal roles in CSCs during tumor progression. | Qiuxia Xiong Liping Jiang Kun Liu Xiulin Jiang Baiyang Liu Yulin Shi Dating Cheng Yong Duan Cuiping Yang Yongbin Chen | 2021 | Signal Transduction and Targeted Therapy2021，6，8： | 1 |
| 18 | Endogenously generated amyloid β increases membrane fluidity in neural 2a cells显示文摘The effect of endogenously generated amyloid β on membrane fluidity was investigated in Neural 2a cells stably expressing Swedish mutant amyloid precursor protein (APPswe). Membrane fluidity was studied by fluorescence polarizability using 1,6-Diphenyl-1,3,5-Hexatriene (DPH) as the fluorescence probe. It was found that the membrane fluidity in APPswe cells was significantly higher than that in its wild type counterparts. Alleviating the effect of amyloid β either by γ secretase activity inhibition or by amyloid antibody treatment decreased membrane fluidity, which indicated an important role of amyloid β in increasing membrane fluidity. Treatment using amyloid β channel blocker, tromethamine and NA4 suggested that channel formed by amyloid β on the cell membrane is a way through which amyloid β takes its membrane fluidizing effect. | NIU Ying SHENG BaiYang SONG Bo LIU LingLing ZHANG XiuFang ZHAO NanMing GONG YanDao | 2009 | Chinese Science Bulletin2009，54，3： | 1 |
| 19 | Functional expression and display of an antibody Fab fragment in Escherichia coli:study of vector designs and culture conditions显示文摘 | Susanne C Baiyang W | 2004 | Protein Expression and Purification2004，34，2： | 1 |
| 20 | Helicobacter pylori colonization of the human gastric epithelium: A bug’s first step is a novel target for us显示文摘 | Bor‐ShyangSheu Hsiao‐BaiYang Yu‐ChunYeh Jiunn‐JongWu | 2009 | Journal of Gastroenterology and Hepatology2009，，1： | 1 |
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