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| 1 | Acute kidney injury and post-reperfusion syndrome in liver transplantation显示文摘In the past decades liver transplantation(LT) has become the treatment of choice for patients with end stage liver disease(ESLD). The chronic shortage of cadaveric organs for transplantation led to the utilization of a greater number of marginal donors such as older donors or donors after circulatory death(DCD). The improved survival of transplanted patients has increased the frequency of long-term complications, in particular chronic kidney disease(CKD). Acute kidney injury(AKI) post-LT has been recently recognized as an important risk factor for the occurrence of denovo CKD in the long-term outcome. The onset of AKI post-LT is multifactorial, with pre-LT risk factors involved, including higher Model for End-stage Liver Disease score, more sever ESLD and pre-existing renal dysfunction, either with intra-operative conditions, in particular ischaemia reperfusion injury responsible for post-reperfusion syndrome(PRS) that can influence recipient's morbidity and mortality. Post-reperfusion syndrome-induced AKI is an important complication post-LT that characterizes kidney involvement caused by PRS with mechanisms not clearly understood and implication on graft and patient survival. Since preLT risk factors may influence intra-operative events responsible for PRS-induced AKI, we aim to consider all the relevant aspects involved in PRS-induced AKI in the setting of LT and to identify all studies that better clarified the specific mechanisms linking PRS and AKI. A Pub Med search was conducted using the terms liver transplantation AND acute kidney injury; liver transplantation AND post-reperfusion syndrome; acute kidney injury AND post-reperfusion syndrome; acute kidney injury AND DCD AND liver transplantation. Five hundred seventy four articles were retrieved on Pub Med search. Results were limited to title/abstract of English-language articles published between 2000 and 2015. Twenty-three studies were identified that specifically evaluated incidence, risk factors and outcome for patients developing PRS-induced AKI in liver transplantation. In order to identify intra-operative risk factors/mechanisms specifically involved in PRSinduced AKI, avoiding confounding factors, we have limited our study to 'acute kidney injury AND DCD AND liver transplantation'. Accordingly, three out of five studies were selected for our purpose. | Ilaria Umbro Francesca Tinti Irene Scalera Felicity Evison Bridget Gunson Adnan Sharif James Ferguson Paolo Muiesan Anna Paola Mitterhofer | 2016 | World Journal of Gastroenterology2016，22，42： | 16 |
| 2 | A striking local esophageal cytokine expression profile in eosinophilic esophagitis显示文摘 | Carine Blanchard Emily M. Stucke Beatriz Rodriguez-Jimenez Karen Burwinkel Margaret H. Collins Annette Ahrens Eileen S. Alexander Bridget K. Buckmeier Butz Sean C. Jameson Ajay Kaul James P. Franciosi Jonathan P. Kushner Philip E. Putnam J. Pablo Abonia M | 2010 | The Journal of Allergy and Clinical Immunology2010，，1： | 3 |
| 3 | Cardiovascular morbidity and mortality after orthotopic liver transplantation显示文摘 | Simon D. Johnston Joan K. Morris Rob Cramb Bridget K. Gunson James Neuberger | 2002 | Transplantation2002，，6： | 2 |
| 4 | Portal hypertension in polycystic liver disease patients does not affect wait-list or immediate post-liver transplantation outcomes显示文摘AIM To establish the impact of portal hypertension(PH) on wait-list/post-transplant outcomes in patients with polycystic liver disease(PCLD) listed for liver transplantation. METHODS A retrospective single-centre case controlled study of consecutive patients listed for liver transplantation over 12 years was performed from our centre. PH in the PCLD cohort was defined by the one or more of following parameters:(1) presence of radiological or endoscopic documented varices from our own centre or the referral centre;(2) splenomegaly(> 11 cm) on radiology inabsence of splenic cysts accounting for increased imaging size;(3) thrombocytopenia(platelets < 150 × 109/L); or(4) ascites without radiological evidence of hepatic venous outflow obstruction from a single cyst. RESULTS Forty-seven PCLD patients(F: M = 42: 5) were listed for liver transplantation(LT)(single organ, n = 35; combined liver-kidney transplantation, n = 12) with 19 patients(40.4%) having PH. When comparing the PH group with non-PH group, the mean listing age(PH group, 50.6(6.4); non-PH group, 47.1(7.4) years; P = 0.101), median listing MELD(PH group, 12; non-PH group, 11; P = 0.422) median listing UKELD score(PH group, 48; non-PH group, 46; P = 0.344) and need for renal replacement therapy(P = 0.317) were similar. In the patients who underwent LT alone, there was no difference in the duration of ICU stay(PH, 3 d; non-PH, 2 d; P = 0.188), hospital stay length(PH, 9 d; non-PH, 10 d; P = 0.973), or frequency of renal replacement therapy(PH, 2/8; non-PH, 1/14; P = 0.121) in the immediate post-transplantation period. CONCLUSION Clinically apparent portal hypertension in patients with PCLD listed for liver transplantation does not appear to have a major impact on wait-list or peri-transplant morbidity. | Neil Rajoriya Dhiraj Tripathi Joanna A Leithead Bridget K Gunson Sophie Lord James W Ferguson Gideon M Hirschfield | 2016 | World Journal of Gastroenterology2016，22，45： | 2 |
| 5 | Potential of Blood Eosinophils, Eosinophil-Derived Neurotoxin, and Eotaxin-3 as Biomarkers of Eosinophilic Esophagitis显示文摘 | Michael R. Konikoff Carine Blanchard Cassie Kirby Bridget K. Buckmeier Mitchell B. Cohen James E. Heubi Philip E. Putnam Marc E. Rothenberg | 2006 | Clinical Gastroenterology and Hepatology2006，，： | 1 |
| 6 | The impact of disease recurrence on graft survival following liver transplantation: a single centre experience显示文摘 | Ian A Rowe Kerry Webb Bridget K Gunson Naimish Mehta Sayeed Haque James Neuberger | 2008 | Transplant International2008，，5： | 1 |
| 7 | Presidential speechmaking style: Emotional response to micro-expressions of facial affect显示文摘 | Patrick A. Stewart Bridget M. Waller James N. Schubert | 2009 | Motivation and Emotion2009，，2： | 1 |
| 8 | Identification, epidemiology, and chronicity of pediatric esophageal eosinophilia, 1982-1999显示文摘 | Charles W. DeBrosse Margaret H. Collins Bridget K. Buckmeier Butz Casey L. Allen Eileen C. King Amal H. Assa’ad J. Pablo Abonia Philip E. Putnam Marc E. Rothenberg James P. Franciosi | 2010 | The Journal of Allergy and Clinical Immunology2010，，： | 1 |
| 9 | Colorectal cancer in patients with inflammatory bowel disease after liver transplantation for primary sclerosing cholangitis显示文摘 | Alonso Vera Bridget K. Gunson Val Ussatoff Peter Nightingale Daniel Candinas Simon Radley A. David Mayer John A.C. Buckels Paul McMaster James Neuberger Darius F. Mirza | 2003 | Transplantation2003，，12： | 1 |
| 10 | Incidence of Cancers Following Orthotopic Liver Transplantation in a Single Center: Comparison with National Cancer Incidence Rates for England and Wales显示文摘 | Ye H. Oo Bridget K. Gunson Robert J. Lancashire Kar K. Cheng James M. Neuberger | 2005 | Transplantation2005，，6： | 1 |
| 11 | Orthotopic liver transplantation for alcoholic liver disease: A retrospective analysis of survival, recidivism, and risk factors predisposing to recidivism显示文摘 | Joanna Mackie Katherine Groves Angela Hoyle Christian Garcia Raquel Garcia Bridget Gunson James Neuberger | 2001 | Liver Transplantation2001，，5： | 1 |
| 12 | Microbial Assessment and Antibiotic Susceptibility Profile of Bacterial Fish Isolates in an Aquaculture Production Site in Mefou Afamba Division of Cameroon显示文摘The practice of integrated fish farming and the use of local fish meal and manure for fish feeding in Cameroon constitute potential sources of resistant pathogenic bacteria in the fish pond environment.Therefore,a periodical and constant monitoring of the microbiological quality of fish pond is imperative.This study was to assess the microbial contamination of Mfou aquaculture production site and evaluate the antibiotic resistance profile of bacterial fish isolates.Samples of pond water(n=36),sediment(n=36),fishmeal(n=12)and African catfish(Clarias gariepinus),kanga(Heterotis niloticus)and Nile Tilapia(Oreochromis niloticus)(n=36,each)were collected to determine TVAC(Total Viable Aerobic Bacterial Count),FC(Fungal Count),SAC(Staphylococcus aureus count),TCC(Total Coliform Count)and FCC(Feacal Coliform Count).The fish skin isolates of S.aureus,Enterobacter sakazakii,Citrobacter freundii,Serratia fonticola,Klebsiella oxytoca,Proteus spp.,Aeromonas hydrophila,Kluyvera spp.,Moraxella spp.,Pasteurella multocida and Pseudomonas fluorescens were tested against penicillin G(10μg),chloramphenicol(30μg),sulfamethoxazole/trimethoprim(25μg),erythromycin(15μg),tetracycline(30μg),using the disk diffusion method.Results reveal a heavy contamination of fish farms with microbial load above the recommended limits.Our study indicates that fish ponds are sources of zoonotic pathogens underlining their epidemiological and clinical relevance.All bacterial isolates were multiresistant with a multiple antibiotic resistance index above 0.2.These data raise concern about the microbial contamination of aquaculture and associated public health risks in Cameroon. | Judith Julie Takadong Tsafack Dimitri Alex Kamgain Tchuenchieu Hippolyte Tene Mouafo Manuela Annick Bengue Baomog Jorelle Jeanne Bimem Adjele Evrard Koupestchop Medjo Imelda Lucresse Nouteza Djuikoo Bridget Tata Ndakoh Chelea Matchawe James Sasanya Gabriel Nama Medoua | 2021 | Journal of Environmental Science and Engineering(B)2021，10，1： | 0 |
| 13 | The effect of top managers'years of experience on innovation显示文摘Managers'characteristics have been identified to have an influence on how they perceive innovation.This study examines the role of top managers'experience and how it influences their propensity to innovate.It employs a logit model to analyze data from the World Bank's Enterprise Surveys,primarily from small-and medium-sized enterprises in Russia.We justify the positive effect of managers'years of experience as an influential factor of enterprises'innovativeness in developing countries.The results show that top managers'years of experience directly affect innovation. | James Okrah Bridget Irene | 2023 | International Journal of Innovation Studies2023，7，3： | 0 |
| 14 | Rostrum abnormalities in the endangered Indian Ocean humpback dolphin(Sousa plumbea)in South Africa显示文摘Morphological abnormalities in wild animals can be indicators of the underlying health of a population and may be determined through routine photographic surveys.Here,we assess unusual rostrum conditions in Indian Ocean humpback dolphins(Sousa plumbea)inhabiting South African coastal waters to understand the rate of prevalence of abnormal rostrums and formulate hypotheses on potential causes.Photographic data were collated from sys-tematic boat surveys and opportunistic sightings,obtained between April 1998 and March 2021 in various regions along the South African coast.Overall,31 unique individuals were found with abnormal rostrum conditions,vary-ing from slight misalignments to severe wounds and/or aberrant morphologies.In most cases,injuries were likely caused by natural events during the animal’s life history such as interactions with sharks and/or reef-associated hunting strategies.Mark–recapture data indicated that individuals had survived with these injuries for up to 10 years.This study reports the highest incidence of rostrum abnormalities in the species.As numbers reflect only those that have survived their injuries,they are considered a minimum estimate.A better understanding of the cause(s)of these injuries is important given the endangered status of this species. | Guilherme FRAINER Simon ELWEN Sasha DINES Bridget JAMES Els VERMEULEN Gwenith PENRY OAlejandra VARGAS-FONSECA Shanan ATKINS Danielle CONRY Tess GRIDLEY | 2023 | Integrative Zoology2023，18，4： | 0 |
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