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| 1 | Blockade of cholecystokinin-2 receptor and cyclooxygenase-2 synergistically induces cell apoptosis, and inhibits the proliferation of human gastric cancer cells in vitro显示文摘Gastrin and cyclooxygenase-2(COX-2) playimportant roles in the carcinogenesis and progression ofgastric cancer.However,it remains unknown whether the combination of cholecystokinin-2(CCK-2) receptor antagonist plus COX-2 inhibitor exerts synergistic anti-tumor effects on human gastric cancer.Here,we demonstrated that the combination of AG-041R(a CCK-2 receptor antagonist) plus NS-398(a selective COX-2 inhibitor) treatment had synergistic effects on proliferation inhibition,apoptosis induction,down-regulation of Bcl-2 and up-regulation of Bax expression in MKN-45 cells.These results indicate that simultaneous targeting of CCK-2 receptor and COX-2 may inhibit gastric cancer development more effectively than targeting either molecule alone.(C)2008 Elsevier Ireland Ltd.All rights reserved. | Sun, W. H. | 2008 | 南京医科大学学报(自然科学版)2008,28,9: | 30 |
| 2 | Voluntary exercise-induced neurogenesis in the postischemic dentate gyrus is associated with spatial memory recovery from stroke显示文摘 | Luo, C. X. Jiang, J. Zhou, Q. G. Zhu, X. J. Wang, W. Zhang, Z. J. Han, X. Zhu, D. Y. | 2007 | 南京医科大学学报(自然科学版)2007,27,10: | 13 |
| 3 | Nature:通过控制血管生长来开发治疗癌症等多种疾病的新型疗法显示文摘最近,一项刊登在国际杂志Nature上的研究报告中,来自耶鲁大学的研究人员通过研究揭示了如何通过控制血管发育来帮助开发治疗心血管疾病以及癌症的新型疗法。 | Yu, Pengchun Wilhelm, Kerstin Dubrac, Alexandre Tung, Joe K. Alves, Tiago C. Fang, Jennifer S. Xie, Yi Zhu, Jie Chen, Zehua De Smet, Frederik Zhang, Jiasheng Jin, Suk-Won Sun, Lele Sun, Hongye Kibbey, Richard G. Hirschi, Karen K. Hay, Nissim Carmeliet, Peter Chittenden, Thomas W. Eichmann, Anne Potente, Michael Simons, Michael | 2017 | 现代生物医学进展2017,17,22: | 9 |
| 4 | Characterization and source apportionment of atmospheric organic and elemental carbon during fall and winter of 2003 in Xi’an, China显示文摘 | Cao J. J. Wu F. Chow J. C. Lee S. C. Li Y. Chen S. W. An Z. S. Fung K. K. Watson J. G. Zhu C. S. Liu S. X | 2005 | Atmospheric Chemistry and Physics2005,,56: | 6 |
| 5 | Characterization and source apportionment of atmospheric organic and elemental carbon during fall and winter of 2003 in Xi’an, China显示文摘 | Cao J. J. Wu F. Chow J. C. Lee S. C. Li Y. Chen S. W. An Z. S. Fung K. K. Watson J. G. Zhu C. S. Liu S. X | 2005 | Atmospheric Chemistry and Physics2005,,56: | 3 |
| 6 | Wide Absorption Spectrum Measuring Methods by DFB-LDs in Water Vapor Detection System显示文摘由分布式的反馈激光二极管(DFB-LDs ) 的宽吸收光谱的二测量方法在检测水蒸汽吸收线被介绍。一个人是扫描方法的分部,并且由当前的调整由温度调整和快光谱调节速度调节范围利用宽光谱。明确地,这个方法被划分一个目标认识到光谱区域进对应于 DFB-LD 的特定的温度的几节,为百由当前的调整扫描每节预定,并且平均数据提起信号到噪音比率( SNR ),然后联合所有节得到整个系列。10 ppmv 的精确性被这个方法与 10 厘米的路径长度在水蒸汽的测量获得了。另外一个是适合方法的数据,基于吸收线形状功能;吸收线能被与部分测量数据适合描述。恰当的吸收线与测量数据被适合很好,并且关联系数(R 平方) 的平方是不亚于 0.99。 | Y. N. LIU J. CHANG J. LIAN Q. WANG G. P. LV W. J. WANG Z. LIU X. Z. LIU S. S. ZHANG Z. L. WANG S. JIANG C. G. ZHU W. WEI B.N. SUN | 2014 | Photonic Sensors2014,4,3: | 2 |
| 7 | Study of backward terahertz radiation from intense picosecond laser–solid interactions using a multichannel calorimeter system显示文摘A multichannel calorimeter system is designed and constructed which is capable of delivering single-shot and broadband spectral measurement of terahertz(THz) radiation generated in intense laser–plasma interactions. The generation mechanism of backward THz radiation(BTR) is studied by using the multichannel calorimeter system in an intense picosecond laser–solid interaction experiment. The dependence of the BTR energy and spectrum on laser energy, target thickness and pre-plasma scale length is obtained. These results indicate that coherent transition radiation is responsible for the low-frequency component(<1 THz) of BTR. It is also observed that a large-scale pre-plasma primarily enhances the high-frequency component(>3 THz) of BTR. | H. Liu G.-Q. Liao Y.-H. Zhang B.-J. Zhu Z. Zhang Y.-T. Li G. G. Scott D. Rusby C. Armstrong E. Zemaityte P. Bradford N. Woolsey P. Huggard P. McKenna D. Neely | 2019 | High Power Laser Science and Engineering2019,7,1: | 2 |
| 8 | EFFECT OF HOT DEFORMATION PARAMETERS ON RECRYSTALLIZATION OF STEEL T91显示文摘In this paper, the recrystallization behavior of steel 9Gr- 1Mo - V-Wb - N at high temperature was studied using Gleeble - 1500 thermalmechanical simulator.The critical conditions of occurrence of dy- namic recrystallization during hot deformation were obtained,and by means of double hit testing with an inter -hit time, the metabynamic recrystallization between rolling passes and its effect factors were also imitated.Additionally,the deformation activation energy of T91 steel,the relationship between critical stress,strain, temperature, and strain rate were regressed respectively, the results were sati- sfied. | F. X. Zhu C. Liu G. Z. Chui and D. F. Gao (State Key Lab. of Rolling and Autoation, Northeastem University, Shenyang 110006, China) | 2000 | Acta Metallurgica Sinica(English Letters)2000,13,1: | 2 |
| 9 | RFLP tagging of a new semidwarfing gene in rice显示文摘 | C. Z. Liang M. H. Gu X. B. Pan G. H. Liang L. H. Zhu | 1994 | Theoretical and Applied Genetics (-)1994,,6: | 1 |
| 10 | Pitting initiation of 316L stainless steel in the media of sulfate-reducing and iron-oxidizing bacteria显示文摘 | Y. H. Zhang C. M. Xu G. X. Cheng W. S. Zhu | 2007 | Inorganic Materials2007,,6: | 1 |
| 11 | Preparation of sol-gel-derived Ca1?x Sr x ZrO3 perovskite dielectric thin films显示文摘 | T. Yu C. H. Chen Y. K. Lu X. F. Chen W. Zhu R. G. Krishnan | 2007 | Journal of Electroceramics (-)2007,,1: | 1 |
| 12 | Study on sub-cycling algorithm for flexible multi-body system—integral theory and implementation flow chart显示文摘 | J. C. Miao P. Zhu G. L. Shi G. L. Chen | 2008 | Computational Mechanics2008,,2: | 1 |
| 13 | RFLP tagging of a new semidwarfing gene in rice显示文摘 | C. Z. Liang M. H. Gu X. B. Pan G. H. Liang L. H. Zhu | 1994 | Theoretical and Applied Genetics (-)1994,,6: | 1 |
| 14 | A strategy for improving mechanical properties of a fiber reinforced epoxy composite using functionalized carbon nanotubes显示文摘 | Daniel C. Davis Justin W. Wilkerson Jiang Zhu Viktor G. Hadjiev | 2011 | Composites Science and Technology2011,,8: | 1 |
| 15 | Hybridization between transgenic Brassica napus L. and its wild relatives: Brassica rapa L., Raphanus raphanistrum L., Sinapis arvensis L., and Erucastrum gallicum (Willd.) O.E. Schulz显示文摘 | S. I. Warwick M.-J. Simard A. Légère H. J. Beckie L. Braun B. Zhu P. Mason G. Séguin-Swartz C. N. Stewart | 2003 | Theoretical and Applied Genetics2003,,3: | 1 |
| 16 | Multi-photon induced ultraviolet emission from hexagram-shaped ZnO nanorods显示文摘 | G. P. Zhu J. Zhu C. X. Xu X. Li J. P. Liu Y. P. Cui | 2009 | Applied Physics A2009,,2: | 1 |
| 17 | A CCD imaging spectrograph in the improved solar tower of Nanjing University显示文摘 | Y. R. Huang C. Fang M. D. Ding X. F. Gao Z. G. Zhu S. Y. Ying J. Hu Y. Z. Xue | 1995 | Solar Physics1995,,1: | 1 |
| 18 | Effects of temperature and fish oil supplementation on ovarian development and foxl 2 mRNA expression in spotted scat Scatophagus argus显示文摘 | G.‐L. Li M.‐Z. Zhang S.‐P. Deng H.‐P. Chen C.‐H. Zhu | 2015 | J Fish Biol2015,,: | 1 |
| 19 | Influence of training on the response of androgen plasma concentrations to exercise in swimmers显示文摘 | M. Bonifazi E. Bela G. Carli L. Lodi G. Martelli B. Zhu C. Lupo | 1995 | European Journal of Applied Physiology and Occupational Physiology1995,,2: | 1 |
| 20 | Buckypaper-based catalytic electrodes for improving platinum utilization and PEMFC’s performance显示文摘 | W. Zhu D. Ku J.P. Zheng Z. Liang B. Wang C. Zhang S. Walsh G. Au E.J. Plichta | 2010 | Electrochimica Acta2010,,7: | 1 |