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| 1 | Opti cal heterodyne velocity mo dulation spectroscopy enhanced by a magnetic rotation effect显示文摘 | Wang Rongjun Chen Yangqin Cai peipei | 1999 | Chem Phys Lett1999，307，： | 1 |
| 2 | Co-location of QTL for Sclerotinia stem rot resistance and flowering time in Brassica napus显示文摘Sclerotinia stem rot(SSR) caused by Sclerotinia sclerotiorum(Lib.) de Bary is one of the most devastating diseases of Brassica napus worldwide. Both SSR resistance and flowering time(FT) adaptation are major breeding goals in B. napus. However, early maturing rapeseed varieties, which are important for rice-rapeseed rotation in China, are often highly susceptible to SSR. Here, we found that SSR resistance was significantly negatively correlated with FT in a natural population containing 521 rapeseed inbred lines and a double haploid(DH) population with 150 individual lines, both of which had great variation in FT. Four chromosomal regions on A2, A6, C2, and C8 affecting both SSR resistance and FT were identified using quantitative trait loci(QTL) mapping after constructing a high-density genetic map based on single nucleotide polymorphism markers in the DH population.Furthermore, we aligned QTL for the two traits identified in the present and previous studies to the B. napus reference genome, and identified four colocalized QTL hotspots of SSR resistance and FT on A2(0–7.7 Mb), A3(0.8–7.5 Mb), C2(0–15.2 Mb), and C6(20.2–36.6 Mb). Our results revealed a genetic link between SSR resistance and FT in B.napus, which should facilitate the development of effective strategies in both early maturing and SSR resistance breeding and in map-based cloning of SSR resistance QTL. | Jian Wu Peipei Chen Qing Zhao Guangqin Cai Yue Hu Yang Xiang Qingyong Yang Youping Wang Yongming Zhou | 2019 | The Crop Journal2019，7，2： | 1 |
| 3 | Oxidative stress in atrial fibrillation: An emerging role of NADPH oxidase显示文摘 | Ji-Youn Youn Jun Zhang Yixuan Zhang Houzao Chen Depei Liu Peipei Ping James N. Weiss Hua Cai | 2013 | Journal of Molecular and Cellular Cardiology2013，，： | 1 |
| 4 | Thermo-mechanical properties of RTM-made carbon fibre/polyimide composite attaching collar under transient heating显示文摘This study focuses on the thermo-mechanical properties of Carbon Fibre/Polyimide Composite(CFPC)attaching collars under transient heating.The CFPC attaching collars were fabricated by a high-temperature resin transfer moulding process,and their thermo-mechanical properties under the conditions of simultaneous transient heating and bending load were investigated.The results show that the attaching collar tends to fail at 118% of the limit load.The failure mode includes the fracture of the connecting screws,local extrusion damage of the hole edges,and slight ablation damage at the outer plies.And there is no observable residual deformation in the composite attaching collar.Furthermore,considering that the material properties vary with temperature,a progressive damage model based on the sequential thermo-mechanical coupling method was established to study the failure mechanism of the attaching collar.Finally,the damage factor of the CFPC was calculated to assess the safety status of the attaching collar.The results show that the primary damage modes of the composite attaching collar are intralaminar failure,which mainly occurs at the heat insulation layer and the hole edges,and these slightly affect the structural bearing capacity.A good correlation between the experiment and FEA is obtained.The test methods and analysis models proposed contribute to the safety assessment of composite structures under transient heating. | Shengda JIANG Chuyang LUO Peng ZHANG Jianwen BAO Peipei CAI Xufeng XIA | 2023 | Chinese Journal of Aeronautics2023，36，3： | 0 |
| 5 | Optical heterodyne-Zeeman modulation magnetic rotation spectroscopic technique显示文摘Optical heterodyne detection using 500 MHz phase modulation was combined with the Zeeman modulation-magnetic rotation spectroscopy (ZM-MRS) to form a new spectroscopic technique, which effectively reduced the amplitude fluctuation from laser source and greatly improved the signal-to-noise ratio in the detection of transient molecules. | Yangqin Chen Zhiyi Bi Peipei Cai Jingxin Ding Rongjun Wang Jingjing Lu Longsheng Ma | 1999 | Chinese Science Bulletin1999，44，20： | 0 |
| 6 | Rare peptide anchors of HLA class I alleles contribute to the COVID-19 disease severity and T cell memory显示文摘Understanding how human leukocyte antigen(HLA)polymorphism affects both the susceptibility and severity of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection will help to identify individuals at higher risk to better manage and prioritize vaccination at the clinical level and explain the differences in epidemic trends in different regions at the epidemiological level.This study compared the frequencies of HLA class I alleles(HLA-A,B)in 214 coronavirus disease 2019(COVID-19)patients with different disease severity and 35 healthy controls and analyzed the correlations between specific HLA alleles and disease severity and T cell memory.The results showed no significant difference in HLA allele frequencies between COVID-19 patients and healthy controls(P>0.05).The allele HLA-B*13:02 was significantly correlated with the disease severity of COVID-19 patients(P=0.006).After adjustment for age and disease severity,the T cell responses of COVID-19 convalescents with the allele HLA-B*40:01 may be lower at six months(P=0.044)and 12 months(P=0.069).Moreover,these results may be due to their rare peptide anchors by analyzing the binding peptide motifs of these HLA alleles.The study may be valuable for investigating the potential association of specific HLA alleles with SARS-CoV-2 infection. | Xin Wang Jie Zhang Peipei Guo Yuanyuan Guo Xiaonan Yang Maoshun Liu Danni Zhang Yaxin Guo Jianbo Zhan Kun Cai Jikin Zhou Shaobo Dong Jun Liu | 2023 | Biosafety and Health2023，5，6： | 0 |
| 7 | Schiff-base silver nanocomplexes formation on natural biopolymer coated mesoporous silica contributed to the improved curative effect on infectious microbes显示文摘Infectious microbes that spread easily in healthcare facilities remain as the severe threat for the public health,especially among immunocompromised populations.Given the intricate problem of dramatic increase in resistance to common biocides,the development of safe and efficient biocide formulated agents to alleviate drug resistance is highly demanding.In this study,Schiff-base ligands were successfully formed on natural biopolymer of epsilon-poly-L-lysine(ε-PL)decorated aldehyde functionalized mesoporous silica SBA-15(CHO-SBA-15)for the selective coordination of silver ions,which was affirmed by various physicochemical methods.Besides the identified broad-spectrum antibacterial activities,the as-prepared Schiff-base silver nanocomplex(CHO-SBA-15/ε-PL/Ag,CLA-1)exhibited an improved inhibitory effect on infectious pathogen growth typified by Escherichia coli and Staphylococcus aureus in comparison with two control silver complexes without Schiff-base conjugates,SBA-15/ε-PL/Ag and CHO-SBA-15/Ag,respectively.In addition,CLA-1 remarkably inhibited the growth of Mycobacterium tuberculosis due to the excellent antimicrobial activity of silver species.Significantly,CLA-1 kills Candida albicans cells,inhibits biofilm formation,and eliminates preformed biofilms,with no development of resistance during continuous serial passaging.The antifungal activity is connected to disruption of bacterial cell membranes and increased levels of intracellular reactive oxygen species.In mouse models of multidrug-resistant C.albicans infection,CLA-1 exhibited efficient in vivo fungicidal efficacy superior to two antifungal drugs,amphotericin B and fluconazole.Moreover,CLA-1 treatment induces negligible toxicity against normal tissues with safety.Therefore,this study reveals the pivotal role of the molecular design of Schiff-base silver nanocomplex formation on biopolymer surface-functionalized silica mesopores as a green and efficient nanoplatform to tackle infectious microbes. | Ling Cai Yanqiang Huang Yuanyuan Duan Qiao Liu Qilan Xu Jia Jia Jianming Wang Qian Tong Peipei Luo Yujie Wen Luming Peng Qian Wu Xudong Hang Huijun Jiang Ping Zhu Yanmei Yang Boshen Zhou Liping Zeng Hongkai Bi Jin Chen | 2021 | Nano Research2021，14，8： | 0 |
| 8 | Needle-like cobalt phosphide arrays grown on carbon fiber cloth as a binder-free electrode with enhanced lithium storage performance显示文摘Cobalt phosphide(CoP) is a promising anode candidate for lithium-ion batteries(LIBs) due to its high specific capacity and low working potential.However,the poor cycling stability and rate performance,caused by low electrical conductivity and huge volume variation,impede the further practical application of CoP anode materials.Herein,we report an integrated binder-free electrode featuring needle-like CoP arrays grown on carbon fiber cloth(CC) for efficient lithium storage.The as-prepared CoP/CC electrode integrates the advantages of 1 D needle-like CoP arrays for efficient electrolyte wettability and fast cha rge transpo rtation,and 3 D CC substrate for superior mechanical stability,flexibility and high conductivity.As a result,the CoP/CC electrode delivers an initial specific capacity of 1283 mAh/g and initial Coulombic effeciencies of 85.4%,which are much higher than that of conventional CoP electrode.Notably,the Co P/CC electrode shows outstanding cycling performance up to 400 cycles at 0.5 A/cm^(2) and excellent rate performance with a discharge capacity of 549 mAh/g even at 5 A/cm^(2).This work demonstrates the great potential of integrated CoP/CC hybrid as efficient bind-free and freestanding electrode for LIBs and future flexible electronic devices. | Ze Zhang Peipei Zhu Chao Li Ji Yu Jianxin Cai Zhenyu Yang | 2021 | Chinese Chemical Letters2021，32，1： | 0 |
| 9 | Pulmonary rehabilitation protocols in urgent lung transplantation patients显示文摘BACKGROUND:Prolonged invasive respiratory support and extracorporeal membrane oxygenation(ECMO)in patients requiring urgent lung transplantation(ULTx)present signifi cant challenges to clinical practice due to severe underlying diseases and complex conditions.The aim of the study was to report the clinical outcomes of patients who received ULTx and followed the perioperative rehabilitation protocol implemented in a lung transplant center.METHODS:A retrospective analysis was conducted in ULTx patients who required preoperative invasive mechanical ventilation(IMV)and ECMO between January 2018 and January 2023.Data were retrieved from electronic medical records at our lung transplant center.RESULTS:Fourteen patients(mean age 57.43±10.97 years;12 males,2 females)underwent ULTx with bridging ECMO and IMV.The mean body mass index was 23.94±3.33 kg/m²,and the mean Acute Physiology and Chronic Health Evaluation(APACHE)II score was 21.50±3.96.The Nutritional Risk Screening 2002(NRS 2002)scores were≥3.ULTx was performed after an 8.5-day waiting period(interquartile interval[IQR]5.0-26.5 d).Following the surgeries,the average lengths of ECMO and IMV were 1.0(IQR 1.0-2.0)d and 5.0(IQR 3.0-7.3)d,respectively.The total length of hospital stay was 60.1±30.8 d,with an average intensive care unit stay of 38.3±22.9 d and post-operative hospitalization stay of 45.8±26.1 d.Two patients died within 30 d after ULTx,with a 30-day survival rate of 85.71%.CONCLUSION:Patients receiving ULTx showed an acceptable short-term survival rate,validating the practicality and safety of the treatment protocols implemented in our center. | Fei Zeng Lingyun Cai Luyao Guo Meijuan Lan Jiangshuyuan Liang Peipei Gu | 2024 | World Journal of Emergency Medicine2024，15，1： | 0 |
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