|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The levels, sources and reactivity of volatile organic compounds in a typical urban area of Northeast China显示文摘Air concentrations of volatile organic compounds(VOCs) were continually measured at a monitoring site in Shenyang from 20 August to 16 September 2017. The average concentrations of alkanes, alkenes, aromatics and carbonyls were 28.54, 6.30, 5.59 and9.78 ppbv, respectively. Seven sources were identified by the Positive Matrix Factorization model based on the measurement data of VOCs and CO. Vehicle exhaust contributed the most(36.15%) to the total propene-equivalent concentration of the measured VOCs,followed by combustion emission(16.92%), vegetation emission and secondary formation(14.33%), solvent usage(10.59%), petrochemical industry emission(9.89%), petrol evaporation(6.28%), and liquefied petroleum gas(LPG) usage(5.84%). Vehicle exhaust, solvent usage and combustion emission were found to be the top three VOC sources for O_3 formation potential, accounting for 34.52%, 16.55% and 11.94%, respectively. The diurnal variation of the total VOCs from each source could be well explained by their emission characteristics,e.g., the two peaks of VOC concentrations from LPG usage were in line with the cooking times for breakfast and lunch. Wind rose plots of the VOCs from each source could reveal the possible distribution of the sources around the monitoring site. The O_3 pollution episodes during the measurement period were found to be coincident with the elevation of VOCs, which was mainly due to the air parcel from the southeast direction where petrochemical industry emission was found to be dominant, suggesting that the petrochemical industry emission from the southeast was probably a significant cause of O_3 pollution in Shenyang. | Zhuobiao Ma Chengtang Liu Chenglong Zhang Pengfei Liu Can Ye Chaoyang Xue Di Zhao Jichen Sun Yiming Du Fahe Chai Yujing Mu | 2019 | Journal of Environmental Sciences2019，31，5： | 12 |
| 2 | Overexpressed miR-9 promotes tumor metastasis via targeting E-cadherin in serous ovarian cancer显示文摘MicroRNAs (miRNAs ) 玩在在各种各样的癌症的发展和前进的关键角色。不正常的 miR-9 表示仍然保持模糊,并且卵巢的癌症的变形前进上的一致都没被到达。在这研究,从生物信息学分析的结果证明 E-cadherin mRNA 的 3-UTR 被 miR-9 直接调整。酶记者试金结果证实 miR-9 能直接指向这 3-UTR。在卵巢的癌症织物的 miR-9 和 E-cadherin 表示被 qRT-PCR 确定。移植和侵略被在 SKOV3 和 A2780 愈合弯屈和 Transwell 系统试金检测。qRT-PCR 和西方的污点被执行检测上皮 ? 间充质的联系转变的 mRNA 和蛋白质。Immunofluorescence 技术被用来分析表示和 E-cadherin, N-cadherin,和 vimentin 的 subcellular 本地化。结果证明 miR-9 经常与配对的主要的相比是在变形浆液的卵巢的癌症织物的 upregulated。miR-9 的 Upregulation 能 downregulate E-cadherin 的表示但是 upregulate 间充质的标记(N-cadherin 和 vimentin ) 的表示。miR-9 的 Overexpression 能在卵巢的癌症支持房间移植和侵略,并且这些进程能有效地经由 miR-9 禁止者被禁止。因此,我们的学习证明 miR-9 可以经由指向 E-cadherin 和一条新奇潜在的治疗学的途径控制卵巢的癌症的转移支持卵巢的癌症转移。 | Bo Zhou Hongbin Xu Meng Xia Chaoyang Sun Na Li Ensong Guo Lili Guo Wanying Shan Hao Lu Yifan Wu Yuan Li Degui Yang Danhui Weng Li Meng Junbo Hu Ding Ma Gang Chen Kezhen Li | 2017 | Frontiers of Medicine2017，11，2： | 10 |
| 3 | Hepatitis C Virus Infection Downregulates the Ligands of the Activating Receptor NKG2D显示文摘Natural killer (NK) cells are a major component of the host innate immune defense against various pathogens. Several viruses, including hepatitis C virus (HCV), have developed strategies to evade the NK-cell response. In our study, we found HCV infection could trigger DNA damage response by both ataxia telangiectasia mutated (ATM) and ATM- and Rad3-related (ATR) pathways. Recent reports had revealed that NKG2D ligands (NK cell-activating ligands) were upregulated when a major DNA damage checkpoint pathway was activated. However, here we found that DNA damage response was activated but NKG2D ligands were downregulated upon HCV infection. Further studies showed that the protease NS3/4A of HCV which had been shown relation with immune invasion contributed to the reduced expression of NKG2D ligands. These findings provide a novel insight into the mechanisms evolved by HCV to escape from the NK cell response. | Chaoyang Wen Xiang He Hongfang Ma Ningbo Hou Congwen Wei Ting Song Yanhong Zhang Liping Sun Qingjun Ma Hui Zhong | 2008 | Cellular & Molecular Immunology2008，5，6： | 6 |
| 4 | Acupoint combinations used for treatment of Alzheimer's disease: A data mining analysis显示文摘OBJECTIVE: To identify the acupoint combinations used in the treatment of Alzheimer's disease(AD).METHODS: The clinical literature regarding acupuncture and moxibustion for AD was searched and collected from databases including Chinese Biomedical Medicine, China National Knowledge Infrastructure, Wanfang Database and PubMed. The database of acupuncture and moxibustion prescriptions for AD was established by using Excel software so as to conduct the descriptive analysis, association analysis on the data.RESULTS: Baihui(GV 20), Sishencong(EX-HN 1),Shenmen(HT 7), Zusanli(ST 36), Neiguan(PC 6),Fengchi(GB 20), Taixi(KI 3), Dazhui(GV 14), Shenshu(BL 23), Sanyinjiao(SP 6), Shenting(GV 24), Fenglong(ST 40), Xuanzhong(GB 39), Shuigou(GV 26)and Taichong(LR 3) were of higher frequency in the treatment of AD with acupnucture and moxibustion. Most acupoints were selected from the Governor Vessel. The commonly used acupoints were located on the head, face, neck and lower limbs. The combination of the local acupoints with the distal ones was predominated. The crossing points among the specific points presented the advantage in the treatment. The association analysis indicated that the correlation among Fengchi(GB 20)-Baihui(GV 20) was the strongest, followed by combinations of Dazhui(GV 14)-Baihui(GV 20), Shenshu(BL 23)-Baihui(GV 20) and Neiguan(PC 6)-Baihui(GV 20) and indicated the common rules of the clinical acupoint selection and combination for AD.CONCLUSION: Our findings provide a reference for acupoints selection and combination for AD in clinical acupuncture practice. | Yu Chaochao Wang Li Kong Lihong Shen Feng Ma Chaoyang Du Yanjun Zhou Hua | 2018 | Journal of Traditional Chinese Medicine2018，38，6： | 4 |
| 5 | Antimony transformation and mobilization from stibnite by an antimonite oxidizing bacterium Bosea sp. AS-1显示文摘Soils and waters are heavily contaminated by antimony in Xikuangshan(XKS)mine area.It is widely accepted that oxidative dissolution of sulfide minerals and aqueous dissolution are the most prevalent geochemical mechanisms for the release of Sb to the environment.Bosea sp.AS-1 is an antimonite-oxidizer isolated from the mine slag in Xikuangshan Sb mine.Whole genome sequencing revealed the presence of multiple sulfur-oxidizing genes,antimony(Sb)metabolism genes and carbon fixation genes in AS-1 s genome.We therefore hypothesized that under oxic conditions,AS-1 could mediate the oxidation of sulfide and Sb(Ⅲ)in stibnite(Sb_(2)S_(3))and lead to the release of Sb.Indeed,strain AS-1 was discovered as an autotrophic Sb(Ⅲ)-oxidizer.Antimony mobilization studies conducted with strain AS-1showed significantly enhanced mobilization of Sb,and complete oxidation of released Sb and sulfur to Sb(V)and sulfate.In addition,AS-1 induced a faster release of Sb under heterotrophic condition,and new acicular minerals might form.These findings support the hypothesis that microorganisms play an important role in the mobilization and transformation of Sb in XKS mine area and may contribute to our further understanding of the Sb biogeochemical redox cycle in natural environment. | Li Xiang Chaoyang Liu Deng Liu Liyuan Ma Xuan Qiu Hongmei Wang Xiaolu Lu | 2022 | Journal of Environmental Sciences2022，34，1： | 3 |
| 6 | Classification and influencing factors of rural elderly's vulnerability to health-related poverty in central and western regions of China显示文摘Objective:To calculate the health poverty vulnerability index of elderly households in rural areas of central and western China,and then to classify these samples,lastly to decompose their influencing factors.Methods:First,based on survey data in 2018,the three-stage feasible generalized least squares was used to calculate the health poverty vulnerability index of elderly households,and then combined with whether the household income was below the poverty line and whether the family was healthy poverty vulnerability,the sample households were divided into four categories,and then used multiple unordered logistic regression to analyze various types of influencing factors,and finally used the Shapley index to decompose the contribution of each influencing factor.Results:The average vulnerability of health poverty was 0.5979±0.25199,with 1169 households greater than or equal to 0.5,accounting for 63.26%;the number of households stuck in poverty,temporary poverty,potential poverty,and escaped from poverty were 489,300,680,and 379 households,accounting for 26.46%,16.23%,36.80%,and 20.51%of the total sample;compared with escaped from poverty families,the three variables of marital status,the number of chronically ill patients,and the number of annual hospitalizations were the common influencing factors of other three types families;The Shapley decomposition showed that the interviewees’education level and family members engaged in non-agricultural work have contributed significantly to the three types,however two indicators:time required to visit a medical institution and self-assessment of health status of the main interviewees showed great differences in different types of families.Conclusion:Rural elderly households have a high level of vulnerability to health poverty;potential poverty households and persistent poverty households account for a large proportion,and continuous intervention should be carried out;it is necessary to unify the implementation of basic poverty alleviation work,but also to enhance refined management capabilities and adopt differentiated intervention measures. | Qin Xiang Chaoyang Yan Ying Ma Hui Liao Jing Wang | 2021 | Global Health Journal2021，5，3： | 2 |
| 7 | Genomic Insight into the Antimicrobial Resistance of Streptococcus Suis-Six Countries,2011-2019显示文摘Summary What is already known on this topic?Streptococcus suis(S.suis)is a zoonotic pathogen causing disease in humans and animals,and the emergence of its increased resistance to antimicrobial agents has become a significant challenge in many countries. | Lichao Ma Wanjiang Zhang Jingyun Ma Qingpo Cui Chaoyang Zhang Peng Zhang Chengtao Sun Huarun Sun Yao Zhu Shaolin Wang Shuangyang Ding Gongzheng Hu Zhangqi Shen | 2021 | China CDC weekly2021，3，47： | 2 |
| 8 | A 16-channel gated integrator for high-resolution energy spectroscopy systems显示文摘A 16-channel gated integrator(GI) module following semi-Gaussian shaping amplifiers was developed for high-resolution energy spectroscopy systems at Institute of Modern Physics,Chinese Academy of Sciences.This GI solved the ballistic deficit problem by integrating the signal until all the charge was collected from the detector at counting rates up to 100 K.In this paper,a fast shaper was used to optimize the gate logic to ensure nonlinearity of the GI less than 0.17%;and a novel compensation approach,to reduce the charge injection from the switches in the GI; and a T-switch configuration,to eliminate leakage current in the reset switch. | ZHOU Chaoyang SU Hong KONG Jie DONG Chengfu QIAN Yi YANG Haibo MA Xiaoli | 2012 | Nuclear Science and Techniques2012，23，4： | 1 |
| 9 | What is the purpose of launching World Journal of Biological Chemistry?显示文摘The first issue of World Journal of Biological Chemistry (WJBC ), whose preparatory work was initiated on July 01, 2009, will be published on January 26, 2010. The WJBC Editorial Board has now been established and consists of 341 distinguished experts from 37 countries. Our purpose of launching WJBC is to publish peer-reviewed, high-quality articles via an open-access online publishing model, thereby acting as a platform for communication between peers and the wider public, and maximizing the benefits to editorial board members, authors and readers. | Lian-Sheng Ma, Beijing Baishideng BioMed Scientific Co., Ltd., Room 903, Building D, Ocean International Center, No. 62 Dongsihuan Zhonglu, Chaoyang District, Beijing 100025, China | 2010 | World Journal of Biological Chemistry2010，1，1： | 1 |
| 10 | Preparative separation and purification of Rosavin in Rhodiola Rosea by macroporous adsorption resins显示文摘 | MA Chaoyang TAO Guangjun TANG Jian | 2009 | Separation and Purification Technology2009，69，： | 1 |
| 11 | Preparative sep- aration and purification of rosavin in Rhodiola rosea by macro- porous adsorption resins显示文摘 | Ma Chaoyang Tao Guangjun Tang Jian | 2009 | Separation and Purification Technol- ogy2009，69，1： | 1 |
| 12 | Characterization of a Novel Gene, srpA, Conferring Resistance to Streptogramin A, Pleuromutilins, and Lincosamides in Streptococcus suis显示文摘Antimicrobial resistance is undoubtedly one of the greatest global health threats. The emergence of multidrug-resistant(MDR) Gram-positive pathogens, such as methicillin-resistant Staphylococcus aureus(MRSA), vancomycin-resistant Enterococcus faecium(VRE), and β-lactamase-resistant Streptococcus pneumonia, has severely limited our antibiotic arsenal. Numerous ribosome-targeting antibiotics, especially pleuromutilins, oxazolidinones, and streptogramins, are viewed as promising alternatives against aggressive MDR pathogens. In this study, we identified a new adenosine triphosphate(ATP)-binding cassete(ABC)-F family determinant, srp A, in Streptococcus suis(S. suis) by means of a comparative analysis of the whole-genome sequences of tiamulin(TIA)-resistant and TIA-sensitive bacteria. Functional cloning confirmed that the deduced gene can mediate cross-resistance to pleuromutilins, lincosamides, and streptogramin A in S. suis and S. aureus. A sequence alignment revealed that Srp A shares the highest amino acid identity with Vga(E)(36%) and shows canonical characteristics of ABC-F family members.In Srp A-ribosome docked compounds, the extended loop region of Srp A approaches the valnemulinbinding pocket in the ribosome peptidyl-transferase center and competes with bound valnemulin. A detailed mutational analysis of the loop residues confirmed that this domain is crucial for Srp A activity,as substitutions or truncations of this region affect the efficiency and specificity of antibiotic resistance.Intracellular antibiotics accumulation indicated that Srp A does not act as an efflux pump, while a ribosome binding assay supported the protective effects of Srp A on the ribosome by preventing antibiotic binding as well as displacing bound drugs. These findings clarify the mechanisms underlying resistance to ribosomal antibiotics. | Chaoyang Zhang Lu Liu Peng Zhang Jingpo Cui Xiaoxia Qin Lichao Ma Kun Han Zhanhui Wang Shaolin Wang Shuangyang Ding Zhangqi Shen | 2022 | Engineering2022，8，2： | 1 |
| 13 | Preparation,physicochemical characterization and application of acetylated lotus rhizome starches显示文摘 | Sun Suling Zhang Ganwei Ma Chaoyang | 2016 | Carbohydrate Polymers2016，，135： | 1 |
| 14 | Preparative separation and purification of rosavin in Rhodiola rosea by macroporous adsorption resins显示文摘 | Chaoyang Ma Guangjun Tao Jian Tang | 2009 | Separation and Purification Technology2009，69，： | 1 |
| 15 | Preparative separation and purification of rosavin in Rhodiola rosea by macroporous adsorption resins显示文摘 | MA Chaoyang TAO Guangjun Tang Jian | 2009 | Separation and Purification Technology2009，69，1： | 1 |
| 16 | Circularly polarized luminescence induced by excimer based on pyrene-modified binaphthol显示文摘A new chiral bromobinaphthol-pyrene compound was developed to achieve a green circularly polarized luminescence(CPL)from its excimer with a dissymmetry factor(|glum|)value of 4.3×10^-3 and a high quantum yieldΦF,solid up to 55.9%,while no CPL signals could be observed for the blue luminescence from unimolecule.Meanwhile,reversal CPL signals can be observed from both concentrated solution and solid. | Chaoyang Wang Tao Jiang Xiang Ma | 2020 | Chinese Chemical Letters2020，31，11： | 0 |
| 17 | Large transverse thermoelectric figure of merit in a topological Dirac semimetal显示文摘The Seebeck effect encounters a few fundamental constraints hindering its thermoelectric(TE)conversion efficiency.Most notably,there are the charge compensation of electrons and holes that diminishes this effect,and the Wiedemann-Franz(WF)law that makes independent optimization of the corresponding electrical and thermal conductivities impossible.Here,we demonstrate that in the topological Dirac semimetal Cd3As2 the Nernst effect,i.e.,the transverse counterpart of the Seebeck effect,can generate a large TE figure of merit zNT.At room temperature,zNT≈0.5 in a small field of 2 T and it significantly surmounts its longitudinal counterpart for any field.A large Nernst effect is generically expected in topological semimetals,benefiting from both the bipolar transport of compensated electrons and holes and their high mobilities.In this case,heat and charge transport are orthogonal,i.e.,not intertwined by the WF law anymore.More importantly,further optimization of zNT by tuning the Fermi level to the Dirac node can be anticipated due to not only the enhanced bipolar transport,but also the anomalous Nernst effect arising from a pronounced Berry curvature.A combination of the topologically trivial and nontrivial advantages promises to open a new avenue towards high-efficient transverse thermoelectricity. | JunSen Xiang SiLe Hu Meng Lyu WenLiang Zhu ChaoYang Ma ZiYu Chen Frank Steglich GenFu Chen PeiJie Sun | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，3： | 0 |
| 18 | Are our clone detectors good enough?An empirical study of code effects by obfuscation显示文摘Clone detection has received much attention in many fields such as malicious code detection,vulnerability hunting,and code copyright infringement detection.However,cyber criminals may obfuscate code to impede violation detection.To date,few studies have investigated the robustness of clone detectors,especially in-fashion deep learning-based ones,against obfuscation.Meanwhile,most of these studies only measure the difference between one code snippet and its obfuscation version.However,in reality,the attackers may modify the original code before obfuscating it.Then what we should evaluate is the detection of obfuscated code from cloned code,not the original code.For this,we conduct a comprehensive study evaluating 3 popular deep-learning based clone detectors and 6 commonly used traditional ones.Regarding the data,we collect 6512 clone pairs of five types from the dataset BigCloneBench and obfuscate one program of each pair via 64 strategies of 6 state-of-art commercial obfuscators.We also collect 1424 non-clone pairs to evaluate the false positives.In sum,a benchmark of 524,148 code pairs(either clone or not)are generated,which are passed to clone detectors for evaluation.To automate the evaluation,we develop one uniform evaluation framework,integrating the clone detectors and obfuscators.The results bring us interesting findings on how obfuscation affects the performance of clone detection and what is the difference between traditional and deep learning-based clone detectors.In addition,we conduct manual code reviews to uncover the root cause of the phenomenon and give suggestions to users from different perspectives. | Weihao Huang Guozhu Meng Chaoyang Lin Qiucun Yan Kai Chen Zhuo Ma | 2023 | Cybersecurity2023，6，4： | 0 |
| 19 | What is the purpose of launching World Journal of Gastrointestinal Surgery?显示文摘The first issue of World Journal of Gastrointestinal Surgery(WJGS),whose preparatory work was initiated on September 27,2008,will be published on November 30,2009.The WJGS Editorial Board has now been established and consists of 328 distinguished experts from 35 countries.Our purpose of launching WJGS is to publish peer-reviewed,high-quality articles via an open-access online publishing model,thereby acting as a platform for communication between peers and the wider public,and maximizing the benefi ts to editorial board members,authors and readers. | Lian-Sheng Ma,Beijing Baishideng BioMed Scientific Co.,Ltd.,Room 903,Building D,Ocean International Center,No.62 Dongsihuan Zhonglu,Chaoyang District,Beijing 100025,China | 2009 | World Journal of Gastrointestinal Surgery2009，1，1： | 0 |
| 20 | pIIIA/N2期非小细胞肺癌患者外科治疗的预后分析(英文)显示文摘Objective: The aim of the study was to identify prognostic factors in non-small-cell lung cancer (NSCLC) with N2 nodal involvement.Methods: A retrospective analysis of disease free survival and 5-year survival for NSCLC patients who underwent primary surgical resection without neoadjuvant chemotherapy were performed.Between January 1998 and May 2004,133 patients were enrolled.Several factors such as age,sex,skip metastasis,number of N2 lymph node stations,type of resection,histology,adjuvant therapy etc.,were recorded and analyzed.SPSS 16.0 software was used.Results: Overall 5-year survival for 133 patients was 32.33%,5-year survival for single N2 station and multiple N2 stations sub-groups were 39.62% and 27.50% respectively,and 5-year survival for cN0–1 and cN2 sub-groups were 37.78% and 20.93% respectively.COX regression analysis revealed that number of N2 station (P = 0.013,OR: 0.490,95% CI: 0.427–0.781) and cN status (P = 0.009,OR: 0.607,95% CI: 0.372–0.992) were two favorable prognostic factors of survival.Conclusion: Number of N2 station and cN status were two favorable prognostic factors of survival.In restrict enrolled circumstances,after combined therapy made up of surgery and postoperative adjuvant therapy have been performed,satisfied survival could be achieved. | Zhenrong Zhang Deruo Liu Yongqing Guo Bin Shi Yanchu Tian Zhiyi Song Yanning Shou Haitao Zhang Chaoyang Liang Zaiyong Wang Tong Bao Qjanli Ma | 2011 | The Chinese-German Journal of Clinical Oncology2011，10，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员