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| 1 | A subset of IL-17+ mesenchymal stem cells possesses anti-Candida albicans effect显示文摘骨头髓间充质的干细胞(MSC ) 与深刻 immunomodulatory 性质包括出生后的祖先房间的一张异构的人口,例如 Foxp3 + 的 upregulation 规章的 T 房间(Tregs ) 和 Th17 房间的 downregulation。然而,它是未知的是否不同 MSC subpopulations 拥有 immunomodulatory 的一样的范围功能。这里,我们证明生产 IL-17 的单个导出殖民地的 MSC 的一个子集与体积 MSC 人口不同因为它不能 upregulate Tregs, downregulate Th17 房间,或改善在一只大肠炎老鼠的疾病显型当模特儿。机械学地,我们揭示那 IL-17,由这些 MSC 生产了,激活 NFκ B 小径到 downregulate TGF-β在 MSC 的生产,导致基于 MSC 的 immunomodulation 的废除。而且,我们显示出那 NFκ B 能直接绑在 TGF-β倡导者区域将调整 TGF-β在 MSC 的表示。而且,这些 IL-17 + MSC 在 C 在 vitro 和治疗学的效果拥有 anti-Candida albicans 生长效果。感染 albicans 的老鼠。在摘要,这研究证明 MSC 包含能够禁止 C 的一个 IL-17 + 子集。albicans 生长,而是 attenuating 经由 NFκ 的基于 MSC 的免疫力的抑制; TGF-β 的调停 B 的 downregulation;。 | Ruili Yang Yi Liu Peyman Kelk Cunye Qu Kentaro Akiyama Chider Chen Ikiru Atsuta WanJun Chen Yanheng Zhou Songtao Shi | 2013 | Cell Research2013，23，1： | 8 |
| 2 | Mesenchymal-Stem-Cell-Induced Immunoregulation Involves FAS-Ligand-/FAS-Mediated T Cell Apoptosis显示文摘 | Kentaro Akiyama Chider Chen DanDan Wang Xingtian Xu Cunye Qu Takayoshi Yamaza Tao Cai WanJun Chen Lingyun Sun Songtao Shi | 2012 | Cell Stem Cell2012，，5： | 2 |
| 3 | In Vivo and In Vitro Pharmacological Studies of Methoxycarbonyl-Carboetomidate显示文摘 | Ervin Pejo Joseph F. Cotten Elizabeth W. Kelly Ri Le Ge Gregory D. Cuny Joydev K. Laha Jifeng Liu Xiang Jie Lin Douglas E. Raines | 2012 | Anesthesia & Analgesia2012，，： | 2 |
| 4 | The two-pore channel TPCN2 mediates NAADP-dependent Ca2+-release from lysosomal stores显示文摘 | Xiangang Zong Michael Schieder Hartmut Cuny Stefanie Fenske Christian Gruner Katrin R?tzer Oliver Griesbeck Hartmann Harz Martin Biel Christian Wahl-Schott | | 0，2009，： | 1 |
| 5 | Demystifying CT For Non-Computer Scientists显示文摘 | Cuny J Snyder L Wing J M | | 0，，3： | 1 |
| 6 | Numerical-Experimental Confrontation in the Simulation of Tool/Abradable Material Interaction显示文摘 | Alain Bataily Marion Cuny Mathias Legrand | | 0，，： | 1 |
| 7 | Induction of Global Stress Response During the First Step of Escherichia coli Plate Growth显示文摘 | CUNY C LESBATS M DUKAN S | | 0，，3： | 1 |
| 8 | Use of intraoperative monitoring of somatosensory evoked potentials to prevent ischaemic stroke after surgical exclusion of middle cerebral artery aneurysms显示文摘 | G. Penchet P. Arné E. Cuny P. Monteil H. Loiseau J.-P. Castel | 2007 | Acta Neurochirurgica2007，，4： | 1 |
| 9 | Elevated Heart-Type Fatty Acid-Binding Protein Levels on Admission Predict an Adverse Outcome in Normotensive Patients With Acute Pulmonary Embolism显示文摘 | Claudia Dellas Miriam Puls Mareike Lankeit Katrin Sch?fer Mayumi Cuny Maik Berner Gerd Hasenfuss Stavros Konstantinides | 2010 | Journal of the American College of Cardiology2010，，19： | 1 |
| 10 | Physiopathology of chronic subdural hematoma显示文摘 | Cuny E | | 0，，05： | 1 |
| 11 | Reduced attention shift in response to auditory changes in subjects with tinnitus显示文摘 | Cuny C Norena A Massioui FE | | 0，，05： | 1 |
| 12 | Evolving Window Zone Selection method followed by Independent Component Analysis as useful chemometric tools to discriminate between grapefruit juice, orange juice and blends显示文摘 | M. Cuny G. Le Gall I.J. Colquhoun M. Lees D.N. Rutledge | 2007 | Analytica Chimica Acta2007，，2： | 1 |
| 13 | Use of intraoperative moni-toring of somatosensory evoked potentials to prevent ischaemic stroke after surgical exclusion of middle cerebral artery aneu-rysms显示文摘 | Penchet G Arne P Cuny E | | 0，，： | 1 |
| 14 | The two-pore channel TPCN2 mediates NAADP-dependent Ca2+-release from lysosomal stores显示文摘 | Xiangang Zong Michael Schieder Hartmut Cuny Stefanie Fenske Christian Gruner Katrin R?tzer Oliver Griesbeck Hartmann Harz Martin Biel Christian Wahl-Schott | 2009 | Pflügers Archiv - European Journal of Physiology2009，，5： | 1 |
| 15 | Microsatellite markers for population genetic studies in Aedes aegypti (Diptera: Culicidae) from C?te d’Ivoire: evidence for a microgeographic genetic differentiation of mosquitoes from Bouaké显示文摘 | S. Ravel J.-P. Hervé S. Diarrassouba A. Kone G. Cuny | 2002 | Acta Tropica2002，，1： | 1 |
| 16 | Induced Neural Stem Cells Generated from Rat Fibroblasts显示文摘The generation of induced tissue-specifc stem cells has been hampered by the lack of well-established methods for the maintenance of pure tissue-specifc stem cells like the ones we have for embryonic stem(ES)cell cultures.Using a cocktail of cytokines and small molecules,we demonstrate that primitive neural stem(NS)cells derived from mouse ES cells and rat embryos can be maintained.Furthermore,using the same set of cytokines and small molecules,we show that induced NS(iNS)cells can be generated from rat fbroblasts by forced expression of the transcriptional factors Oct4,Sox2 and c-Myc.The generation and long-term maintenance of iNS cells could have wide and momentous implications. | Guangjun Xi Pingfang Hu Cunye Qu Shenfeng Qiu Chang Tong Qi-Long Ying | 2013 | Genomics, Proteomics & Bioinformatics2013，11，5： | 1 |
| 17 | The Time-Dependence Growth of Metallic Crystal Ultrafine Particles显示文摘By using x-ray diffraction technique and transmission electron microscopy the in situ growth property of metal crystal ultrafine particles(CUFP)which are deposited on the silica-substrates have been studied experimentially.It is found that the diffraction intensity and the nucleus diameter of Ag CUFP are grown with time by power-law.Thus,the changes of crystal nucleus and the structure of Ag CUFP with time shows a crystallization trend,at the same time,the in situ growth of Ag CUFP displays a self-similarity character. | LIU Cunye DENG Zhaojing | 1992 | Chinese Physics Letters1992，9，12： | 0 |
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