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| 1 | 深度神经肌肉阻滞改善腹腔镜手术中术野显露:系统性综述-meta分析显示文摘神经肌肉阻滞常用于腹腔镜手术,可通过松弛腹壁肌肉,防止突发性肌肉收缩,改善手术条件。而常规采用深度肌松目前仍存在争议,故此就有关评价深度肌松对腹腔镜手术中术野显露和转归影响的临床研究,进行系统性综述-meta分析。文献检索情况:自建库至2016年12月间,收录在Medline、Embase以及Central databases数据库中的临床研究,类型包括随机试验、病例交叉研究和队列研究;共纳入12项评价深度肌松对术野显露影响的临床研究。系统评价的结果表明,与中度肌松比较,深度肌松可优化腹腔镜手术中术野显露[术野显露评分(1-5分)均数差0.65分,95%可信区间0.47~0.83分],且有利于低压气腹的实施。深度肌松还可降低麻醉恢复后疼痛程度[疼痛评分均数差-0.52分,95%可信区间-0.71~-0.32分]。由此认为,深度肌松可改善腹腔镜手术条件,并降低术后疼痛程度,而可否降低术中并发症发生,改善术后转归,有待进一步研究。本系统性综述的方法学于2016年7月27日在PROSPERO "国际前瞻性系统综述登记平台"预先详述并注册(注册号:CRD42016042144)。 | M.H.Bruintjes E. V. van Helden A. E. Braat A. Dahan G. J. Scheffer C. J. van Laarhoven M.C.Warle | 2017 | 中华麻醉学杂志2017，37，9： | 12 |
| 2 | Nitric Oxide in Plants: Production and Cross-talk with Ca^2+ Signaling显示文摘氮的氧化物(没有) 是在动物在生理的过程的一个宽数组执行关键功能的两价的气体。过去的几年在植物关于它的角色揭示了大部分。被硝酸盐 reductase (NR ) 并且经由化学小径不从亚硝酸根综合,这很好被建立。为没有生产是从由到目前为止非识别的酶的 L 精氨酸的 catalysed 的一条其他的在小径的出现正在增加证据。矛盾的结果处于特定的生理的条件关于这些酶的各自的参与被报导了。尽管大部分尚待被证明,我们假设这些矛盾能被说明因为由过去常不压制合成的药理学代理人的有限特性而且由象在硝酸盐的硝酸盐可渗透的阴离子隧道的迟钝一样的 L 精氨酸的减少的内容 reductase- 或 nitrate/nitrite-deficient 种。另一个未解决的问题使不在植物位于效果下面的分子的机制担心。这里,我们提供证据包括 MAPK 和 SnRK2 的第二送信人 Ca2+ ,以及蛋白质 kinases,是很嘴巧的调停人没有信号。这些调查结果关于在植物的不基于的发信号的开的新观点。 | Angelique Besson-Bard Cecile Courtois Adrien Gauthier Jennifer Dahan Grazyna Dobrowolska Sylvain Jeandroz Alain Pugin David Wendehenne | 2008 | Molecular Plant2008，1，2： | 9 |
| 3 | Corrosion Inhibition of Carbon Steel in Hot Hydrochloric Acid Solutions显示文摘 | T. Y. Soror(Chemistry Department, Faculty of Science, Cairo University, Cairo, Egypt)H. A.E1 Dahan(Department of Electrochemistry and Corrosion, National Research Centre, Dokki, Cairo, Egypt)N. G.E1 Sayed Ammer(Central Chemical Laboratories, Sabtia, Cairo | 1999 | Journal of Materials Science & Technology1999，15，6： | 4 |
| 4 | Enhancing rice grain production by manipulating the naturally evolved cis-regulatory element-containing inverted repeat sequence of OsREM20显示文摘Grain number per panicle(GNP)is an important agronomic trait that contributes to rice grain yield.Despite its importance in rice breeding,the molecular mechanism underlying GNP regulation remains largely unknown.In this study,we identified a previously unrecognized regulatory gene that controls GNP in rice,Oryza sativa REPRODUCTIVE MERISTEM 20(OsREM20),which encodes a B3 domain transcription factor.Through genetic analysis and transgenic validation we found that genetic variation in the CArG box-containing inverted repeat(IR)sequence of the OsREM20 promoter alters its expression level and contributes to GNP variation among rice varieties.Furthermore,we revealed that the IR sequence regulates OsREM20 expression by affecting the direct binding of OsMADS34 to the CArG box within the IR sequence.Interestingly,the divergent pOsREM20IR and pOsREM20ΔIR alleles were found to originate from different Oryza rufipogon accessions,and were independently inherited into the japonica and indica subspecies,respectively,during domestication.Importantly,we demonstrated that IR sequence variations in the OsREM20 promoter can be utilized for germplasm improvement through either genome editing or traditional breeding.Taken together,our study characterizes novel genetic variations responsible for GNP diversity in rice,reveals the underlying molecular mechanism in the regulation of agronomically important gene expression,and provides a promising strategy for improving rice production by manipulating the cis-regulatory element-containing IR sequence. | Xiaowei Wu Yan Liang Hengbin Gao Jiyao Wang Yan Zhao Lekai Hua Yundong Yuan Ahong Wang Xiaohui Zhang Jiafan Liu Jie Zhou Xiangbing Meng Dahan Zhang Shaoyang Lin Xuehui Huang Bin Han Jiayang Li Yonghong Wang | 2021 | Molecular Plant2021，14，6： | 3 |
| 5 | Low phosphorus promotes NSP1–NSP2 heterodimerization to enhance strigolactone biosynthesis and regulate shoot and root architecture in rice显示文摘Phosphorus is an essential macronutrient for plant development and metabolism,and plants have evolved ingenious mechanisms to overcome phosphate(Pi)starvation.However,the molecular mechanisms underlying the regulation of shoot and root architecture by low phosphorus conditions and the coordinated utilization of Pi and nitrogen remain largely unclear.Here,we show that Nodulation Signaling Pathway 1(NSP1)and NSP2 regulate rice tiller number by promoting the biosynthesis of strigolactones(SLs),a class of phytohormones with fundamental effects on plant architecture and environmental responses.We found that NSP1 and NSP2 are induced by Oryza sativa PHOSPHATE STARVATION RESPONSE2(OsPHR2)in response to low-Pi stress and form a complex to directly bind the promoters of SL biosynthesis genes,thus markedly increasing SL biosynthesis in rice.Interestingly,the NSP1/2–SL signaling module represses the expression of CROWN ROOTLESS 1(CRL1),a newly identified early SL-responsive gene in roots,to restrain lateral root density under Pi deficiency.We also demonstrated that GR24^(4DO) treatment under normal conditions inhibits the expression of OsNRTs and OsAMTs to suppress nitrogen absorption but enhances the expression of OsPTs to promote Pi absorption,thus facilitating the balance between nitrogen and phosphorus uptake in rice.Importantly,we found that NSP1p:NSP1 and NSP2p:NSP2 transgenic plants show improved agronomic traits and grain yield under low-and medium-phosphorus conditions.Taken together,these results revealed a novel regulatory mechanism of SL biosynthesis and signaling in response to Pi starvation,providing genetic resources for improving plant architecture and nutrient-use efficiency in low-Pi environments. | Kun Yuan Hao Zhang Chaoji Yu Nan Luo Jijun Yan Shuang Zheng Qingliang Hu Dahan Zhang Liquan Kou Xiangbing Meng Yanhui Jing Mingjiang Chen Xinwei Ban Zongyun Yan Zefu Lu Jian Wu Yu Zhao Yan Liang Yonghong Wang Guosheng Xiong Jinfang Chu Ertao Wang Jiayang Li Bing Wang | 2023 | Molecular Plant2023，16，11： | 2 |
| 6 | Modulated fatty acid desaturation via overexpression of two distinct ω‐3 desaturases differentially alters tolerance to various abiotic stresses in transgenic tobacco cells and plants显示文摘 | MengZhang RivkaBarg MinganYin YardenaGueta‐Dahan AliciaLeikin‐Frenkel YehiamSalts SaraShabtai GozalBen‐Hayyim | 2005 | The Plant Journal2005，，3： | 2 |
| 7 | Value of pelvic embolization in the management of severe postpartum hemorrhage due to placenta accreta, increta or percreta显示文摘 | Philippe Soyer Olivier Morel Yann Fargeaudou Marc Sirol Fabrice Staub Mourad Boudiaf Henri Dahan Alexandre Mebazaa Emmanuel Barranger Olivier le Dref | 2010 | European Journal of Radiology2010，，3： | 2 |
| 8 | Adalimumab drug and antibody levels as predictors of clinical and laboratory response in patients with Crohn’s disease显示文摘 | Y. Mazor R. Almog U. Kopylov D. Ben Hur A. Blatt A. Dahan M. Waterman S. Ben‐Horin Y. Chowers | 2014 | Aliment Pharmacol Ther2014，，6： | 2 |
| 9 | Opposite clear corneal incisions to correct pre-existing astigmatism in cataract surgery显示文摘 | Lever J Dahan E | 2000 | J Cataract Refract Surg2000，25，5： | 1 |
| 10 | Propofol reduces the distribution and clearance of midazolam 显示文摘 | Lichtenbelt B J Olofsen E Dahan MA | 2010 | Anesthesia &Analgesia2010，110，6： | 1 |
| 11 | On fracture structure andpreferential flow in unsaturated chalk显示文摘 | DAHAN O NATIV R ADAR E M | 2000 | Ground Water2000，38，44： | 1 |
| 12 | Pathogenesis of carbohydrate-induced hypertriglyceridemia using HepG2 cells as a model system显示文摘 | Cianflone K Dahan S Monge JC | 1992 | Arterioscler Thromb1992，12，3： | 1 |
| 13 | Radiofrequency ablation for treatment of mild to moderate obstructive sleep apnea显示文摘 | Blumen MB Dahan S Fleury B | 2002 | Laryngoscope2002，112，11： | 1 |
| 14 | Study of resistivity and Majority carrier Concentra- tion of silicon damaged by neutron irradiation 显示文摘 | CROITORU N DAHAN R RANCOITA P G | 1998 | Nuclear Physics B1998，61，： | 1 |
| 15 | Sunitinib malate for the treatment of pancreatic neuroendocrine tumors显示文摘 | Raymond E Dahan L Raoul JL | 2011 | N Engl J Med2011，364，6： | 1 |
| 16 | The Predictive Power of Intemet- based Product Concept Testing Using Visual Depiction and Animationm显示文摘 | Dahan E Srinkasan V | 2000 | Journal of Product Innovation Management2000，17，2： | 1 |
| 17 | Rapid and specific isolation of intact mitochondria from Arabidopsis leaves显示文摘Mitochondria carry out many essential metabolic processes, the dynamic of which impacts most aspects of cellular physiology(Balk and Leaver, 2001;Rose and Sheahan, 2012). Therefore, characterizing the real-time metabolism of mitochondria is of great biological significance. | Lilan Luo Yajun He Qian Xu Wenhui Lyu Jijun Yan Peiyong Xin Dahan Zhang Jinfang Chu Jiayang Li Hong Yu | 2020 | Journal of Genetics and Genomics2020，47，1： | 1 |
| 18 | Adenocarcinomas of the distalesophagus and gastric cardia:what chemotherapy or chemoradiotherapy for recurrent or metastatic disease显示文摘 | Seitz JF Duffaud F Dahan L | 2001 | Cancer Radiother2001，5，1： | 1 |
| 19 | Comparison of the respiratory effects of intravenous buprenorphine and fentanyl in humans and rats 显示文摘 | Dahan A Yassen A Bijl H | 2005 | Br-J-Anaesth2005，94，6： | 1 |
| 20 | Sunitinib malate for the treatment of pancreatic neuroendocrine tumors 显示文摘 | Raymond E Dahan L Raoul J L | 2011 | NEnglJMed2011，364，6： | 1 |
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