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| 1 | 基于可再生能源的全球电气化路径与远景分析显示文摘为满足清洁能源转型的深度脱碳要求,描绘一幅基于可再生能源电气化的蓝图,全面阐述了基于可再生能源的电气化路径,分析其在工业、交通、建筑等部门面对的挑战,评估不同技术路径的应用前景和效益,提出政策、技术和市场方面的措施建议。研究结果表明,基于可再生能源的电气化路径不仅技术可行,同时也会产生重要的经济和社会效益。 | 洪博文 MIKETA Asami GIELEN Dolf RUSSO Daniel JANEIRO Luis BOSHELL Francisco WAGNER Nicholas TAIBI Emanuele | 2020 | 中国电力2020，53，3： | 17 |
| 2 | Review of current diagnostic methods and advances in Helicobacter pylori diagnostics in the era of next generation sequencing显示文摘Helicobacter pylori(H.pylori)infection is highly prevalent in the human population and may lead to severe gastrointestinal pathology including gastric and duodenal ulcers,mucosa associated tissue lymphoma and gastric adenocarcinoma.In recent years,an alarming increase in antimicrobial resistance and subsequently failing empiric H.pylori eradication therapies have been noted worldwide,also in many European countries.Therefore,rapid and accurate determination of H.pylori’s antibiotic susceptibility prior to the administration of eradication regimens becomes ever more important.Traditionally,detection of H.pylori and its antimicrobial resistance is done by culture and phenotypic drug susceptibility testing that are cumbersome with a long turn-around-time.Recent advances in diagnostics provide new tools,like real-time polymerase chain reaction(PCR)and line probe assays,to diagnose H.pylori infection and antimicrobial resistance to certain antibiotics,directly from clinical specimens.Moreover,high-throughput whole genome sequencing technologies allow the rapid analysis of the pathogen’s genome,thereby allowing identification of resistance mutations and associated antibiotic resistance.In the first part of this review,we will give an overview on currently available diagnostic methods for detection of H.pylori and its drug resistance and their implementation in H.pylori management.The second part of the review focusses on the use of next generation sequencing technology in H.pylori research.To this end,we conducted a literature search for original research articles in English using the terms“Helicobacter”,“transcriptomic”,“transcriptome”,“next generation sequencing”and“whole genome sequencing”.This review is aimed to bridge the gap between current diagnostic practice(histology,rapid urease test,H.pylori culture,PCR and line probe assays)and new sequencing technologies and their potential implementation in diagnostic laboratory settings in order to complement the currently recommended H.pylori management guidelines and subsequently improve public health. | Daniel Pohl Peter M Keller Valentine Bordier Karoline Wagner | 2019 | World Journal of Gastroenterology2019，25，32： | 15 |
| 3 | Increased incidence of and microbiologic changes in pyogenic liver abscesses in the Mexican population显示文摘BACKGROUND Pyogenic liver abscess(PLA)is a rare disease with an estimated incidence that varies widely across the globe,being as high as 115.4/100000 habitants in Taiwan and as low as 1.1-1.2/100000 habitants in Europe and Canada.Even though there are multiple microorganisms capable of producing an abscess in the liver,including Entamoeba histolytica,fungi,and viruses,most abscesses are derived from bacterial infections.The epidemiology of PLA in Mexico is currently unknown.AIM To describe the clinical,demographic and microbiologic characteristics of PLA in Mexico.METHODS This is a retrospective study carried out in two centers,and included patients seen between 2006 and 2018 with the diagnosis of pyogenic abscess.We collected demographic,clinical,and microbiological information,treatment,complications,and outcomes.A logistic regression analysis was used to determine the association between different variables and mortality rates.RESULTS A total of 345 patients were included in this study.233(67.5%)had confirmed PLA,133(30%)patients had no positive culture and negative serology and 9(2.5%)had mixed abscesses.The mean age was 50 years(ranging from 16-97 years)and 63%were female.65%of the patients had positive cultures for Extended Spectrum Beta-Lactamases(ESBL)-Escherichia coli and Klebsiella pneumoniae.Cefotaxime was administered in 60%of cases.The most common sources of infection were ascending cholangitis and cholecystitis in 34(10%)and 31(9%),respectively.The median length of hospital stay was 14 d.165 patients underwent percutaneous catheter drainage.The inpatient mortality rate was 63%.Immunocompromised state[OR 3.9,95%CI:1.42-10.46],ESBL-Escherichia coli[OR 6.7,95%CI:2.7-16.2]and Klebsiella pneumoniae[OR 4-8,95%CI:1.6-14.4]predicted inpatient mortality by multivariate analysis.CONCLUSION The prevalence of PLA is increasing in Mexico and has a very high mortality rate.ESBL-Escherichia coli and Klebsiella pneumoniae are the most common microorganisms causing PLA and are independent predictors of inpatient mortality. | Juanita Pérez-Escobar Wagner Ramirez-Quesada Daniel Alejandro Calle-Rodas Luis Alberto Chi-Cervera Nalu Navarro-Alvarez Jorge Aquino-Matus Juan Pablo Ramírez-Hinojosa Carlos Moctezuma-Velázquez Aldo Torre | 2020 | World Journal of Hepatology2020，12，10： | 5 |
| 4 | α-Fetoprotein, Des-γ Carboxyprothrombin, and Lectin-Bound α-Fetoprotein in Early Hepatocellular Carcinoma显示文摘 | Jorge A. Marrero Ziding Feng Yinghui Wang Mindie H. Nguyen Alex S. Befeler Lewis R. Roberts K. Rajender Reddy Denise Harnois Josep M. Llovet Daniel Normolle Jackie Dalhgren David Chia Anna S. Lok Paul D. Wagner Sudhir Srivastava Myron Schwartz | 2009 | Gastroenterology2009，，1： | 3 |
| 5 | Circulating MicroRNA-208b and MicroRNA-499 Reflect Myocardial Damage in Cardiovascular Disease显示文摘 | Maarten F. Corsten Robert Dennert Sylvia Jochems Tatiana Kuznetsova Yvan Devaux Leon Hofstra Daniel R. Wagner Jan A. Staessen Stephane Heymans Blanche Schroen | 2010 | Circulation: Cardiovascular Genetics2010，，6： | 2 |
| 6 | Diagnosis of Ascaris lumbricoides infection using capsule endoscopy显示文摘Ascaris lumbricoides (A. lumbricoides ) is the most common intestinal roundworm parasite, infecting approximately one quarter of the world's population. Infection can lead to various complications because it can spread along the gastrointestinal tract. Although A. lumbricoides infection is a serious healthcare issue in developing countries, it now also has a worldwide distribution as a result of increased immigration and travel. Intestinal obstruction is the most common complication of A. lumbricoides infection, potentially leading to even more serious consequences such as small bowel perforation and peritonitis. Diagnosis is based primarily on stool samples and the patient's history. Early diagnosis, aided in part by knowledge of the local prevalence, can result in early treatment, thereby preventing surgical complications associated with intestinal obstruction. Further, delay in diagnosis may have fatal consequences. Capsule endoscopy can serve as a crucial, non-invasive diagnostic toolfor A. lumbricoides infection, especially when other diagnostic methods have failed to detect the parasite. We report a case of A. lumbricoides infection that resulted in intestinal obstruction at the level of the ileum. Both stool sample examination and open surgery failed to indicate the presence of A. lumbricoides, and the cause of the obstruction was only revealed by capsule endoscopy. The patient was treated with anthelmintics. | Eduardo Tomohissa Yamashita Wagner Takahashi Daniel Yuiti Kuwashima Tiago Ribeiro Langoni Adriana Costa-Genzini | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，4： | 2 |
| 7 | Novel p19 Protein Engages IL-12p40 to Form a Cytokine, IL-23, with Biological Activities Similar as Well as Distinct from IL-12显示文摘 | Birgit Oppmann Robin Lesley Bianca Blom Jackie C Timans Yuming Xu Brisdell Hunte Felix Vega Nancy Yu Jing Wang Komal Singh Francesca Zonin Elena Vaisberg Tatyana Churakova Man-ru Liu Daniel Gorman Janet Wagner Sandra Zurawski Yong-Jun Liu John S Abrams Ke | 2000 | Immunity2000，，5： | 2 |
| 8 | 一种高强度钢的超高周疲劳及热耗散研究显示文摘利用超声疲劳试验设备在20kHz频率下研究了一种高强度钢的超高周疲劳性能,试验持续到109次循环,得到了室温环境及不同循环比(R=0.01和R=0.1)的S-N曲线,试验结果显示,疲劳强度在105~109次循环范围内随着循环次数的增加而减小。断面表面的SEM检查结果表明,疲劳裂纹的生成导致疲劳损伤,且亚表面裂纹起源在长寿命范围内。试验结果表明,试件全寿命的99.87%贡献于亚表面裂纹的形成。 | 邵闯 BATHIAS Cloude WAGNER Daniele 陶华 薛红前 | 2010 | 材料导报2010，24，16： | 2 |
| 9 | Complement Fragment 3a Priming of Umbilical Cord Blood Progenitors: Safety Profile显示文摘 | Claudio G. Brunstein David H. McKenna Todd E. DeFor Darin Sumstad Philip Paul Daniel J. Weisdorf Mariusz Ratajczak Mary J. Laughlin John E. Wagner | 2013 | Biology of Blood and Marrow Transplantation2013，，： | 1 |
| 10 | One size does not fit all: The emerging frontier in large-scale marine conservation显示文摘 | Robert J. Toonen T. ‘Aulani Wilhelm Sara M. Maxwell Daniel Wagner Brian W. Bowen Charles R.C. Sheppard Sue M. Taei Tukabu Teroroko Russell Moffitt Carlos F. Gaymer Lance Morgan Nai‘a Lewis Anne L.S. Sheppard John Parks Alan M. Friedlander | 2013 | Marine Pollution Bulletin . 2013 (1-2)2013，，1： | 1 |
| 11 | Analyzing the cost effectiveness of Santiago, Chile’s policy of using urban forests to improve air quality显示文摘 | Francisco J. Escobedo John E. Wagner David J. Nowak Carmen Luz De la Maza Manuel Rodriguez Daniel E. Crane | 2007 | Journal of Environmental Management2007，，： | 1 |
| 12 | A denosine inhibits lipopolysaccharide induced secretion of tumor necrosis factor-α in the failing human heart显示文摘 | Daniel R Wagner MD | 1998 | Circulaition1998，97，： | 1 |
| 13 | Mammalian Cell Cytotoxicity Analysis of Soybean Rust Fungicides 显示文摘 | Daniel S L Hartman G L Wagner E D | 2007 | Bull Environ Contam Toxicol2007，78，： | 1 |
| 14 | Reduced-Intensity Allogeneic Transplant in Patients Older Than 55 Years: Unrelated Umbilical Cord Blood Is Safe and Effective for Patients without a Matched Related Donor显示文摘 | Navneet S. Majhail Claudio G. Brunstein Marcie Tomblyn Avis J. Thomas Jeffrey S. Miller Mukta Arora Dan S. Kaufman Linda J. Burns Arne Slungaard Philip B. McGlave John E. Wagner Daniel J. Weisdorf | 2008 | Biology of Blood and Marrow Transplantation2008，，3： | 1 |
| 15 | Postoperative hypoesthesia and pain: qualitative assessment after open and laparoscopic inguinal hernia repair显示文摘 | Guido Beldi Non Haupt Ramin Ipaktchi Markus Wagner Daniel Candinas | 2008 | Surgical Endoscopy2008，，1： | 1 |
| 16 | Enhanced production of chikungunya virusqike particles using a high-pH adapted Spodoptera frugiperda insect cell line显示文摘 | Wagner J M Pajerowski J D Daniels C L | 2014 | PloS One2014，9，4： | 1 |
| 17 | Polymer-nanoinclusion interactions in carbon nanotube based polyacrylonitrile extruded and electrospun fibers显示文摘 | Linda Vaisman Ellen Wachtel H. Daniel Wagner Gad Marom | 2007 | Polymer2007，，23： | 1 |
| 18 | Chronic Graft-Versus-Host Disease (cGVHD) following Unrelated Donor Hematopoietic Stem Cell Transplantation (HSCT): Higher Response Rate In Recipients of Unrelated Donor (URD) Umbilical Cord Blood (UCB)显示文摘 | Mukta Arora Sriharsha Nagaraj John E. Wagner Juliet N. Barker Claudio G. Brunstein Linda J. Burns Todd E. DeFor Margaret L. McMillan Jeffrey S. Miller Daniel J. Weisdorf | 2007 | Biology of Blood and Marrow Transplantation2007，，10： | 1 |
| 19 | Stimulation of soluble guanylyl cyclase inhibit s mesangial cell proliferation and mat rix accumulation in experimental glomerulonephritis显示文摘 | Daniel C Wagner A | 2005 | Am J Physiol Renal Physiol2005，288，： | 1 |
| 20 | MicroRNA-150: A Novel Marker of Left Ventricular Remodeling After Acute Myocardial Infarction显示文摘 | Yvan Devaux Melanie Vausort Gerry P. McCann Jennifer Zangrando Dominic Kelly Naveed Razvi Lu Zhang Leong L. Ng Daniel R. Wagner Iain B. Squire | 2013 | Circulation: Cardiovascular Genetics2013，，： | 1 |
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