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| 1 | Global characterization and monitoring of forest cover using Landsat data: opportunities and challenges显示文摘The compilation of global Landsat data-sets and the ever-lowering costs of computing now make it feasible to monitor the Earth’s land cover at Landsat resolutions of 30 m.In this article,we describe the methods to create global products of forest cover and cover change at Landsat resolutions.Nevertheless,there are many challenges in ensuring the creation of high-quality products.And we propose various ways in which the challenges can be overcome.Among the challenges are the need for atmospheric correction,incorrect calibration coefficients in some of the data-sets,the different phenologies between compila-tions,the need for terrain correction,the lack of consistent reference data for training and accuracy assessment,and the need for highly automated character-ization and change detection.We propose and evaluate the creation and use of surface reflectance products,improved selection of scenes to reduce phenological differences,terrain illumination correction,automated training selection,and the use of information extraction procedures robust to errors in training data along with several other issues.At several stages we use Moderate Resolution Spectro-radiometer data and products to assist our analysis.A global working prototype product of forest cover and forest cover change is included. | John R.Townshend Jeffrey G.Masek Chengquan Huang Eric.F.Vermote Feng Gao Saurabh Channan Joseph O.Sexton Min Feng Raghuram Narasimhan Dohyung Kim Kuan Song Danxia Song Xiao-Peng Song Praveen Noojipady Bin Tan Matthew C.Hansen Mengxue Li Robert E.Wolfe | 2012 | International Journal of Digital Earth2012，5，5： | 10 |
| 2 | Comparison of the short-term and long-term outcomes of laparoscopic hysterectomies and of abdominal hysterectomies: a case study of 4,895 patients in the Guangxi Zhuang Autonomous Region, China显示文摘Background: To evaluate the short-term and long-term outcomes after laparoscopic hysterectomy(LH) compared with abdominal hysterectomy(AH) in case of benign gynecological disease. Methods: A multi-center cohort retrospective comparative study of population among 4,895 hysterectomies(3,539 LH vs.1,356 AH) between 2007 and 2013 was involved. Operative time(OT), estimated blood loss(EBL), intra-operative and post-operative complications, passing flatus; days with indwelling catheter, questionnaires covering pelvic floor functions and sexual functions were assessed.Results: The EBL(174.1±157.4 vs. 263.1±183.2 cc, LH and AH groups, respectively), passing flatus(38.7±14.1 vs. 48.1±13.2 hours), days with indwelling catheter(1.5±0.6 vs. 2.2±0.8 days), use of analgesics(6.5% vs. 73.1%), intra-operative complication rate(2.4% vs. 4.1%), post-operative complication rate(2.3% vs. 5.7%), post-operative constipation(12.1% vs. 24.6%), mild and serious stress urinary incontinence(SUI) post-operative(P<0.001; P=0.014), and proportion of Female Sexual Functioning Index(FSFI) total score <26.55 post-operative(P<0.001) of the LH group were significantly less than those of AH group. There wereno significant differences in OT(106.5±34.5 vs. 106.2±40.3 min) between the two groups.Conclusions: LH is a safe and efficient operation for improving patients' long-term quality of life(Qo L), and LH is a cost-effectiveness procedure for treating benign gynecological disease. LH is superior to AH due to reduced EBL, reduced post-operative pain and earlier passing flatus. | Hongying He Zhijun Yang Dingyuan Zeng Jiangtao Fan Xiaoxia Hu Yuan Ye Hua Bai YanmingJiang Zhong Lin Zhiying Lei Xinlin Li Lian Li Jinghua Gan Ying Lan Xiongzhi Tang Danxia Wang Junsong Jiang Xiaoyan Wu Meiying Li Xiaoqing Ren Xiaomin Yang Mei Liu Qinmei Wang Fuyan jiang Li Li | 2016 | Chinese Journal of Cancer Research2016，28，2： | 6 |
| 3 | Coagulation factors VII, IX and X are effective antibacterial proteins against drug-resistant Gram-negative bacteria显示文摘Infections caused by drug-resistant“superbugs”pose an urgent public health threat due to the lack of effective drugs;however, certain mammalian proteins with intrinsic antibacterial activity might be underappreciated. Here, we reveal an antibacterial property against Gram-negative bacteria for factors VII, IX and X, three proteins with well-established roles in initiation of the coagulation cascade. These factors exert antibacterial function via their light chains (LCs). Unlike many antibacterial agents that target cell metabolism or the cytoplasmic membrane, the LCs act by hydrolyzing the major components of bacterial outer membrane, lipopolysaccharides, which are crucial for the survival of Gram-negative bacteria. The LC of factor VII exhibits in vitro efficacy towards all Gram-negative bacteria tested, including extensively drug-resistant (XDR) pathogens, at nanomolar concentrations. It is also highly effective in combating XDR Pseudomonas aeruginosa and Acinetobacter baumannii infections in vivo. Through decoding a unique mechanism whereby factors VII, IX and X behave as antimicrobial proteins, this study advances our understanding of the coagulation system in host defense, and suggests that these factors may participate in the pathogenesis of coagulation disorder-related diseases such as sepsis via their dual functions in blood coagulation and resistance to infection. Furthermore, this study may offer new strategies for combating Gram-negative “superbugs”. | Jinwu Chen Xiaojie Li Ling Li Ting Zhang Qing Zhang Fangming Wu Diyue Wang Hongze Hu Changlin Tian Dongsheng Liao Liang Zhao Danxia Song Yongyun Zhao Chuanfang Wu Xu Song | 2019 | Cell Research2019，29，9： | 6 |
| 4 | The evolution of China’s regulation of agricultural biotechnology显示文摘To ensure safe use of genetically modified organisms(GMOs),since 1993,China has made great efforts to establish and improve the safety regulatory system for GMOs.Here,we summarize and analyze the regulatory framework of agricultural GMOs,and the progress in regulatory approval of GM crops in China.In general,the development of GMO safety regulations underwent four stages:exploration(1993–2000),development(2001–2010),improvement(2011–2020)and current(2021-present)stage.The first formal regulation was promulgated in 1993,which provided a basis for further development of the regulations,during the exploration stage,when insect-resistant GM cotton,expressing genes from Bacillus thuringiensis(Bt),was approved for cultivation.During the development stage,the Chinese government issued a series of administrative measures,which covered almost all the fields relative to GMO safety when the basic regulatory system was established.Along with the controversy over GMO safety,the regulations have been further,and greatly improved,during improvement stage.From 2021,a few additional revisions have been made,and meanwhile,the new regulation on gene-edited crops was introduced with the development of biotechnology,forming a relative complete regulation and law system for China.The well-developed GMO regulations establishes a firm basis for safe use of GM crops in China.Currently,GM cotton and GM papaya have been widely grown on a large scale in China that have brought great economic and ecological benefits.In addition,12 corn events,3 soybean events,and 2 rice events have also obtained biosafety certification,but presently,these lines have yet to enter commercial production.However,several GM soybean and corn events have entered pilot industrialization,and can soon be expected to be commercially grown in China.In addition to planting,six GM crops,including soybean,corn,cotton,canola,papaya and sugar beet,with a total of 64 events,have been approved for import as processing material in China. | Jingang Liang Xiaowei Yang Yue Jiao Danxia Wang Qiang Zhao Yu Sun Yunhe Li Kongming Wu | 2022 | aBIOTECH2022，3，4： | 2 |
| 5 | miR-497 modulates multidrug resistance of human cancer cell lines by targeting BCL2显示文摘 | Wei Zhu DanXia Zhu Shiqiang Lu Tongshan Wang Jian Wang Binghua Jiang Yongqian Shu Ping Liu | 2012 | Medical Oncology2012，，1： | 1 |
| 6 | Application of data mining on web and design of tools显示文摘 | XIE Danxia LI Xiaodong | 2002 | Computer Applications2002，21，2： | 1 |
| 7 | Studies on glass transition temperature of ehitosan with four techniques 显示文摘 | Dong Yanming Ruan Yonghong Wang Huiwu Zhao Yaging Bi Danxia | 2004 | Journal of Applied Polymer Science2004，93，15： | 1 |
| 8 | Resist- ant to imipenem in Pseudomonas aeruginosa nosocomial infection risk factors analysis显示文摘 | CHEN Junqing CHEN Danxia HUANG Chengang | 2011 | Chin J Hosp Infect2011，21，11： | 1 |
| 9 | The initial-boundary value problem of a nonlinear thermoelastic beam equations显示文摘 | ZHANG Jianwen WANG Danxia | 2010 | Applied Mechanics and Materials2010，2932，： | 1 |
| 10 | Photonic fractional-order differentiator using an SOI microring resonator with an MMI coupler显示文摘 | SHAHOEI H XU Danxia SCHMID J H | 2013 | IEEE Photonics Technology Letters2013，25，15： | 1 |
| 11 | Continuous slow and fast light generation using a sili- con-on-Insulator microring resonator incorporating a multimode interference coupler显示文摘 | SHAHOEI H XU Danxia SCHMID J H | 2014 | Journal of Light- wave Technology2014，32，22： | 1 |
| 12 | Silicon waveguide modulator based on carrier depletion in periodically interleaved PN junctions 显示文摘 | Li Zhiyong Xu Danxia McKinnon W R | 2009 | Optics Express2009，17，15： | 1 |
| 13 | Laparoscopic uterine fibroids in addition to surgery and other clinical effects of conventional open surgery 显示文摘 | Wang Danxia | 2009 | Shanxi Medical Journal2009，38，7： | 1 |
| 14 | A survey of multicast routing protocols for mobile Ad-hoc networks显示文摘 | Luo Junhai Ye Danxia Xue Liu | 2009 | IEEE Communications Surveys & Tutorials2009，11，1： | 1 |
| 15 | Research on multicast routing protocols for mobile ad hoe networks 显示文摘 | Luo Junhai Liu Xue Ye Danxia | 2008 | Computer Networks2008，52，5： | 1 |
| 16 | Magnetic nanohydroxyapatite/PVA composite hydrogels for promoted osteoblast adhesion and proliferation显示文摘 | Ruixia Hou Guohua Zhang Gaolai Du Danxia Zhan Yang Cong Yajun Cheng Jun Fu | 2013 | Colloids and Surfaces B: Biointerfaces2013，，： | 1 |
| 17 | Research on multicast routing protocols for mobile ad-hoc networks显示文摘 | Luo Junhai Xue Liu Ye Danxia | 2007 | Computer Networks2007，，： | 1 |
| 18 | A designmethodofmagnetoGrheologicalgreasedamperforrailwayvehicleantiGhuntingvibrationandtests显示文摘 | Liao Changrong Zhao Danxia Liu Qiong | 2013 | JournalofViGbrationandShock2013，32，4： | 1 |
| 19 | Application of proprotein convertase subtilisin/kexin type 9 inhibitor, evolocumab, in patients with severe hypertriglyceridemia显示文摘To the Editor:The proprotein convertase subtilisin/kexin type 9(PCSK9)-inhibitor,evolocumab,can bind with PCSK9 in plasma and reduce the degradation of the PCSK9-low density lipoprotein(LDL)receptor complex,thereby reducing LDL levels.[1]In clinical practice,PCSK9 inhibitors can reduce low-density lipoprotein cholesterol(LDL-c)significantly and reduce triglycerides(TG)by about 8%to 17%.[2]We used PCSK9 inhibitors to lower blood lipids in three patients with severe hypertriglyceridemia(HTG)and performed whole-exome sequencing(WES)to analyze the genes that may contribute to hyperlipidemia in detail.We have obtained patients'consent forms.We found that PCSK9 inhibitors significantly reduced blood lipid levels,regardless of the presence of HTG mutations.These results provide new evidence for the use of PCSK9 inhibitors in the treatment of patients with severe HTG. | Yanren Peng Danxia Guo Sijie Jiang Hua Zheng | 2022 | Chinese Medical Journal2022，，6： | 1 |
| 20 | miR-497 modulates multidrug resistance of human cancer cell lines by targeting Bcl-2显示文摘 | Wei Zhu Danxia Zhu Shiqiang Lu | 2012 | Med Oncol2012，29，1： | 1 |
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