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| 1 | Mechanisms of autophagy activation in endothelial cell and their targeting during normothermic machine liver perfusion显示文摘Ischaemia-reperfusion injury(IRI) is the leading cause of injury seen in the liver following transplantation. IRI also causes injury following liver surgery and haemodynamic shock. The first cells within the liver to be injured by IRI are the liver sinusoidal endothelial cells(LSEC). Recent evidence suggests that LSEC coordinate and regulates the livers response to a variety of injuries. It is becoming increasingly apparent that the cyto-protective cellular process of autophagy is a key regulator of IRI. In particular LSEC autophagy may be an essential gatekeeper to the development of IRI. The recent availability of liver perfusion devices has allowed for the therapeutic targeting of autophagy to reduce IRI. In particular normothermic machine liver perfusion(NMP-L) allow the delivery of pharmacological agents to donor livers whilst maintaining physiological temperature and hepatic flow rates. In this review we summarise the current understanding of endothelial autophagy and how this may be manipulated during NMP-L to reduce liver IRI. | Yuri L Boteon Richard Laing Hynek Mergental Gary M Reynolds Darius F Mirza Simon C Afford Ricky H Bhogal | 2017 | World Journal of Gastroenterology2017，23，48： | 4 |
| 2 | Molecular Virology of Hepatitis C Virus(HCV):2006 Update显示文摘 | Volker B Darius M Hubert E | 2006 | Int J Med Sci2006，3，2： | 1 |
| 3 | Acute endophthalmitis following intravitreal triamcinolone acetonide injection显示文摘 | Darius M Moshfeghi Peter K Kaiser Ingrid U Scott Jonathan E Sears Matthew Benz Juan P Sinesterra Richard S Kaiser Sophie J Bakri Raj K Maturi Jonathan Belmont Paul M Beer Timothy G Murray Hugo Quiroz-Mercado William F Mieler | 2003 | American Journal of Ophthalmology2003，，5： | 1 |
| 4 | Small Subunit rDNA sequence analysis of symbiotic dinoflagellates from seven scleractinian corals in a tahitian lagoon 显示文摘 | Darius H T Martin P M V Grimont P A D | 2000 | J Phycol2000，36，： | 1 |
| 5 | The effectof fruit factors on the bruise susceplihility of apples 显示文摘 | Van Zeebroeck M Van Linden V Darius P | 2007 | Postharvest Biology and Technology2007，46，1： | 1 |
| 6 | A stochastic frontier analysis of technical progress, efficiency change and productivity growth in the Pacific Northwest sawmill industry 显示文摘 | TED L H DARIUS M A | 2009 | Forest Policy and Economics2009，11，4： | 1 |
| 7 | Risk of coronary artery disease associated with polymorphism of the cytochrome P450 epoxygenase CYP2J2显示文摘 | Spiecker M Darius H Hankeln T | 2004 | Circulation2004，110，： | 1 |
| 8 | The impacts of changes in federal timber harvest on forest carbon sequestration in western Oregon显示文摘 | Im Eun Ho Adams Darius M Latta Gregory S | 2010 | Canadian Journal of Forest Research-Revue Canadienne De Recherche Forestiere2010，40，9： | 1 |
| 9 | Risk of coronary artery disease associated with polymorphism of a cytochrome P450 epoxygenase CYP2J2显示文摘 | Spieker M Darius H Hankeln T | 2004 | Circulation2004，110，： | 1 |
| 10 | Ciguatera fish toxicity in French Polynesia: Size does not always matter 显示文摘 | Gaboriau M Ponton D Darius HT | 2014 | Toxicon2014，84，： | 1 |
| 11 | 1,8-cineol inhibits nuclear translocation of NF-κB p65 and NF-κB-dependent transcriptional activity显示文摘 | Johannes F.-W. Greiner Janine Müller Marie-Theres Zeuner Stefan Hauser Thorsten Seidel Christin Klenke Lena-Marie Grunwald Timo Schomann Darius Widera Holger Sudhoff Barbara Kaltschmidt Christian Kaltschmidt | 2013 | BBA - Molecular Cell Research2013，，： | 1 |
| 12 | An application of social values for ecosystem services (SolVES) to three natlonM forests in Colorado and Wyoming 显示文摘 | BENSON C S DARIUS J S JESSICA M C | 2014 | Ecological Indicators2014，36，1： | 1 |
| 13 | Acute endophthalmitis following intravitreal triamcinolone acetonide injection显示文摘 | Darius M Moshfeghi Peter K Kaiser Ingrid U Scott Jonathan E Sears Matthew Benz Juan P Sinesterra Richard S Kaiser Sophie J Bakri Raj K Maturi Jonathan Belmont Paul M Beer Timothy G Murray Hugo Quiroz-Mercado William F Mieler | 2003 | American Journal of Ophthalmology2003，，5： | 1 |
| 14 | Genome-Wide Association Study Identifies Variants Associated With Progression of Liver Fibrosis From HCV Infection显示文摘 | Etienne Patin Zoltán Kutalik Julien Guergnon Stéphanie Bibert Bertrand Nalpas Emmanuelle Jouanguy Mona Munteanu Laurence Bousquet Laurent Argiro Philippe Halfon Anne Boland Beat Müllhaupt David Semela Jean–Fran?ois Dufour Markus H. Heim Darius Moradpour A | 2012 | Gastroenterology2012，，5： | 1 |
| 15 | Hepatitis C: molecular virology and antiviral targets显示文摘 | Darius M Volker B Rainer G | 2002 | Trends in Mole Med2002，8，： | 1 |
| 16 | Risk of coronary artery disease associated with polymorphism of a cytoehrome P450 epoxygenase CYP2J2 显示文摘 | Spiecker M Darius H Hankeln T | 2004 | Circulation2004，110，15： | 1 |
| 17 | Risk of coronary artery disease associated with polymorphism of the cytochrome P450 epoxygenase CYP2J2显示文摘 | Darius H Hankeln T | 2004 | Circulation2004，110，15： | 1 |
| 18 | Effect of fluorinated additives or co-solvent on performances of graphite//LiMn2O4 cells cycled at high potential显示文摘Herein,a comprehensive study of electrochemical performances of the combined effect of fluorinated additives;fluoroethylene carbonate(FEC);and tris(2,2,2-trifluoroethyl) phosphite(TTFP) or the 2,2,2-trifluoroethyl methyl carbonate(TFEMC) as co-solvent,on Graphite//LiMn2O4 cells cycled at high potential is reported.On one side,each additive has a specific function,the FEC is dedicated to the negative electrode and the TTFP to the opposite one.The electrolyte mixture with(4% FEC+1% TTFP) additive has shown the best ability to reduce fading of the LiMn2O4 electrode,especially at high rates.On the other side,by studying the comparative thermal and transport properties of the formulated electrolytes with different proportions of TFEMC,we demonstrate that the difference in charge distribution of EMC and TFEMC molecules induced by the presence of fluorine atoms,modifies the solvation model of the Li+cation,and changes its behavior at the CEI interface and impact strongly the electrochemical performances.Finally,the EIS investigation of the LMO/electrolyte interfaces in the presence of TFEMC demonstrates that despite a spontaneous chemical reactivity of the TFEMC at the cathode interface over time,the conductive and good quality CEI is formed,which positively impact the cyclability.This study shows that against LMO surface phenomena,the combination in adequate proportions of fluorinated additives or solvent can be a solution not only to avoid the oxidative reactivity of LMO-cathode,but also to prevent its harmful consequences on the Li-metal or graphite-anode by controlling the solvation of lithium-ion. | Benjamin Flamme Darius JYeadon Satyajit Phadke Mérièm Anouti | 2021 | Journal of Energy Chemistry2021，30，1： | 1 |
| 19 | Risk of coronary artery disease associated with polymorphism of the cytochrome P450 epoxygenase CYP2J2显示文摘 | SPIECKER M DARIUS H HANKELN T | 2004 | Circulation2004，110，12： | 1 |
| 20 | Perioperative chemotherapy with FOLFOX4 and surgery versus surgery alone for resectable liver metastases from colorectal cancer (EORTC Intergroup trial 40983): a randomised controlled trial显示文摘 | Bernard Nordlinger Halfdan Sorbye Bengt Glimelius Graeme J Poston Peter M Schlag Philippe Rougier Wolf O Bechstein John N Primrose Euan T Walpole Meg Finch-Jones Daniel Jaeck Darius Mirza Rowan W Parks Laurence Collette Michel Praet Ullrich Bethe Eric Van | 2008 | The Lancet2008，，9617： | 1 |
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