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| 1 | Predicting lower limb periprosthetic joint infections: A review of risk factors and their classification显示文摘AIM To undertook a systematic review to determine factors that increase a patient's risk of developing lower limb periprosthetic joint infections(PJI).METHODS This systematic review included full-text studies that reviewed risk factors of developing either a hip or knee PJI following a primary arthroplasty published from January 1998 to November 2016. A variety of keywords were used to identify studies through international databases referencing hip arthroplasty, knee arthroplasty, infection, and risk factors. Studies were only included if they included greater than 20 patients in their study cohort, and there was clear documentation of the statistical parameter used; specifically P-value, hazard ratio, relative risk, or/and odds ratio(OR). Furthermore a quality assessment criteria for the individual studies was undertaken to evaluate the presence of record and reporting bias. RESULTS Twenty-seven original studies reviewing risk factors relating to primary total hip and knee arthroplasty infections were included. Four studies(14.8%) reviewed PJI of the hip, 3(11.21%) of the knee, and 20(74.1%) reviewed both joints. Nineteen studies(70.4%) were retrospective and 8(29.6%) prospective. Record bias was identified in the majority of studies(66.7%). The definition of PJI varied amongst the studies but there was a general consensus to define infection by previously validated methods. The most significant risks were the use of preoperative high dose steroids(OR = 21.0, 95%CI: 3.5-127.2, P < 0.001), a BMI above 50(OR = 18.3, P < 0.001), tobacco use(OR = 12.76, 95%CI: 2.47-66.16, P= 0.017), body mass index below 20(OR = 6.00, 95%CI: 1.2-30.9, P = 0.033), diabetes(OR = 5.47, 95%CI: 1.77-16.97, P = 0.003), and coronary artery disease(OR = 5.10, 95%CI: 1.3-19.8, P = 0.017).CONCLUSION We have highlighted the need for the provider to optimise modifiable risk factors, and develop strategies to limit the impact of non-modifiable factors. | David A George Lorenzo Drago Sara Scarponi Enrico Gallazzi Fares S Haddad Carlo L Romano | 2017 | World Journal of Orthopedics2017，8，5： | 3 |
| 2 | Role of Pancreatic Stellate Cells in Pancreatic Cancer Metastasis显示文摘 | Zhihong Xu Alain Vonlaufen Phoebe A. Phillips Eva Fiala-Beer Xuguo Zhang Lu Yang Andrew V. Biankin David Goldstein Romano C. Pirola Jeremy S. Wilson Minoti V. Apte | 2010 | The American Journal of Pathology2010，，5： | 2 |
| 3 | A Pedagogical Treatment of Bilateral Monopoly 显示文摘 | Roger D Blair David L Kaserman Richard E Romano | 1989 | Southern Economic Journal1989，55，4： | 1 |
| 4 | RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein显示文摘 | David Matallanas David Romano Karen Yee | 2007 | Mo12007，27，： | 1 |
| 5 | Mitochondrial oxidative stress and respiratory chain dysfunction account for liver toxicity during amiodarone but not dronedarone administration显示文摘 | Gaetano Serviddio Francesco Bellanti Anna Maria Giudetti Gabriele Vincenzo Gnoni Nazzareno Capitanio Rosanna Tamborra Antonino Davide Romano Maurizio Quinto Maria Blonda Gianluigi Vendemiale Emanuele Altomare | 2011 | Free Radical Biology and Medicine2011，，12： | 1 |
| 6 | Mast Cells Positive to Tryptase and c-Kit Receptor Expressing Cells Correlates with Angiogenesis in Gastric Cancer Patients Surgically Treated显示文摘 | Michele Ammendola Rosario Sacco Giuseppe Sammarco Giuseppe Donato Valeria Zuccalà Roberto Romano Maria Luposella Rosa Patruno Carlo Vallicelli Giorgio Maria Verdecchia Davide Cavaliere Severino Montemurro Girolamo Ranieri Chunping Jiang | 2013 | Gastroenterology Research and Practice2013，，： | 1 |
| 7 | Evolutionary and Functional Analysis of Celiac Risk Loci Reveals SH2B3 as a Protective Factor against Bacterial Infection显示文摘 | Alexandra Zhernakova Clara C. Elbers Bart Ferwerda Jihane Romanos Gosia Trynka Patrick C. Dubois Carolien G.F. de Kovel Lude Franke Marije Oosting Donatella Barisani Maria Teresa Bardella Leo A.B. Joosten Paivi Saavalainen David A. van Heel Carlo Catassi | 2010 | The American Journal of Human Genetics2010，，6： | 1 |
| 8 | Evolutionary and Functional Analysis of Celiac Risk Loci Reveals SH2B3 as a Protective Factor against Bacterial Infection显示文摘 | Alexandra Zhernakova Clara C. Elbers Bart Ferwerda Jihane Romanos Gosia Trynka Patrick C. Dubois Carolien G.F. de Kovel Lude Franke Marije Oosting Donatella Barisani Maria Teresa Bardella Leo A.B. Joosten Paivi Saavalainen David A. van Heel Carlo Catassi | 2010 | The American Journal of Human Genetics2010，，6： | 1 |
| 9 | Mitochondrial oxidative stress and respiratory chain dysfunction account for liver toxicity during amiodarone but not dronedarone administration显示文摘 | Gaetano Serviddio Francesco Bellanti Anna Maria Giudetti Gabriele Vincenzo Gnoni Nazzareno Capitanio Rosanna Tamborra Antonino Davide Romano Maurizio Quinto Maria Blonda Gianluigi Vendemiale Emanuele Altomare | 2011 | Free Radical Biology and Medicine2011，，12： | 1 |
| 10 | Affective temperamental profiles are associated with white matter hyperintensity and suicidal risk in patients with mood disorders显示文摘 | Gianluca Serafini Maurizio Pompili Marco Innamorati Paolo Fusar-Poli Hagop S. Akiskal Zoltan Rihmer David Lester Andrea Romano Irismar Reis de Oliveira Leonardo Strusi Stefano Ferracuti Paolo Girardi Roberto Tatarelli | 2010 | Journal of Affective Disorders2010，，1： | 1 |
| 11 | Periventricular white matter hyperintensities as predictors of suicide attempts in bipolar disorders and unipolar depression显示文摘 | Maurizio Pompili Marco Innamorati J. John Mann Maria A. Oquendo David Lester Antonio Del Casale Gianluca Serafini Silvia Rigucci Andrea Romano Antonino Tamburello Giovanni Manfredi Eleonora De Pisa Stefan Ehrlich Giancarlo Giupponi Mario Amore Roberto Tat | 2008 | Progress in Neuropsychopharmacology & Biological Psychiatry2008，，6： | 1 |
| 12 | Predictors of Outcome at 1 Year in Adolescents With DSM-5 Restrictive Eating Disorders: Report of the National Eating Disorders Quality Improvement Collaborative显示文摘 | Sara F. Forman Nicole McKenzie Rebecca Hehn Maria C. Monge Cynthia J. Kapphahn Kathleen A. Mammel S. Todd Callahan Eric J. Sigel Terrill Bravender Mary Romano Ellen S. Rome Kelly A. Robinson Martin Fisher Joan B. Malizio David S. Rosen Albert C. Hergenroe | 2014 | Journal of Adolescent Health2014，，： | 1 |
| 13 | Long-Term Outcomes of Patients With Acute Coronary Syndrome and Nonobstructive Coronary Artery Disease显示文摘 | Roberta Rossini Davide Capodanno Corrado Lettieri Giuseppe Musumeci Ugo Limbruno Maria Molfese Vincenzo Spatari Paolo Calabria Michele Romano Giuseppe Tarantini Antonello Gavazzi Dominick J. Angiolillo | 2013 | The American Journal of Cardiology2013，，2： | 1 |
| 14 | Early pregnancy diagnosis by palpation per rectum: Influence on embryo/fetal viability in dairy cattle显示文摘 | Juan E. Romano James A. Thompson Duane C. Kraemer Mark E. Westhusin David W. Forrest Michael A. Tomaszweski | 2006 | Theriogenology2006，，3： | 1 |
| 15 | Analysis of HLA and Non-HLA Alleles Can Identify Individuals at High Risk for Celiac Disease显示文摘 | Jihane Romanos Cleo C. van Diemen Ilja M. Nolte Gosia Trynka Alexandra Zhernakova Jingyuan Fu Maria Teresa Bardella Donatella Barisani Ross McManus David A. van Heel Cisca Wijmenga | 2009 | Gastroenterology2009，，3： | 1 |
| 16 | Effect of oral mesalamine on inflammatory response in acute uncomplicated diverticulitis显示文摘AIM: To evaluate the impact of mesalamine administration on inflammatory response in acute uncomplicated diverticulitis.METHODS: We conducted a single centre retrospective cohort study on patients admitted to our surgical department between January 2012 and May 2014 with a computed tomography-confirmed diagnosis of acute uncomplicated diverticulitis. A total of 50 patients were included in the analysis, 20(study group) had received 3.2 g/d of mesalamine starting from the day of admission in addition to the usual standard treatment, 30(control group) had received standard therapy alone. Data was retrieved from a prospective database. Our primary study endpoints were: C reactive protein mean levels over time and their variation from baseline(ΔCRP) over the first three days of treatment. Secondary end points included: mean white blood cell and neutrophile count over time, time before regaining of regular bowel movements(passing of stools), time before reintroduction of food intake, intensity of lower abdominal pain over time, analgesic consumption and length of hospital stay.RESULTS: Patients characteristics and inflammatoryparameters were similar at baseline in the two groups. The evaluation of CRP levels over time showed, in treated patients, a distinct trend towards a faster decrease compared to controls. This difference approached statistical significance on day 2(mean CRP 6.0 +/- 4.2 mg/d L and 10.0 +/- 6.7 mg/d L respectively in study group vs controls, P = 0.055). ΔCRP evaluation evidenced a significantly greater increment of this inflammatory marker in the control group on day 1(P = 0.03). A similar trend towards a faster resolution of inflammation was observed evaluating the total white blood cell count. Neutrophile levels were significantly lower in treated patients on day 2 and on day 3(P < 0.05 for both comparisons). Mesalamine administration was also associated with an earlier reintroduction of food intake(median 1.5 d and 3 d, study group vs controls respectively, P < 0.001) and with a shorter hospital stay(median 5 d and 5.5 d, study group vs controls respectively, P = 0.03).CONCLUSION: Despite its limitations, this study suggests that mesalamine may allow for a faster recovery and for a reduction of inflammatory response in acute uncomplicated diverticulitis. | Luca Nespoli Giulia Lo Bianco Fabio Uggeri Fabrizio Romano Angelo Nespoli Davide Paolo Bernasconi Luca Gianotti | 2015 | World Journal of Gastroenterology2015，21，27： | 0 |
| 17 | Observatory science with eXTP显示文摘In this White Paper we present the potential of the enhanced X-ray Timing and Polarimetry(eXTP) mission for studies related to Observatory Science targets. These include flaring stars, supernova remnants, accreting white dwarfs, low and high mass X-ray binaries, radio quiet and radio loud active galactic nuclei, tidal disruption events, and gamma-ray bursts. eXTP will be excellently suited to study one common aspect of these objects: their often transient nature. Developed by an international Consortium led by the Institute of High Energy Physics of the Chinese Academy of Science, the eXTP mission is expected to be launched in the mid 2020s. | Jean J.M.in 't Zand Enrico Bozzo JinLu Qu Xiang-Dong Li Lorenzo Amati Yang Chen Immacolata Donnarumma Victor Doroshenko Stephen A.Drake Margarita Hernanz Peter A.Jenke Thomas J.Maccarone Simin Mahmoodifar Domitilla de Martino Alessandra De Rosa Elena M.Rossi Antonia Rowlinson Gloria Sala Giulia Stratta Thomas M.Tauris Joern Wilms XueFeng Wu Ping Zhou Iván Agudo Diego Altamirano Jean-Luc Atteia Nils A.andersson M.Cristina Baglio David R.Ballantyne Altan Baykal Ehud Behar Tomaso Belloni Sudip Bhattacharyya Stefano Bianchi Anna Bilous Pere Blay Joao Braga Sφren Brandt Edward F.Brown Niccolo Bucciantini Luciano Burderi Edward M.Cackett Riccardo Campana Sergio Campana Piergiorgio Casella Yuri Cavecchi Frank Chambers Liang Chen Yu-Peng Chen Jér?me Chenevez Maria Chernyakova ChiChuan Jin Riccardo Ciolfi Elisa Costantini Andrew Cumming Antonino D'Aì Zi-Gao Dai Filippo D'Ammando Massimiliano De Pasquale Nathalie Degenaar Melania Del Santo Valerio D'Elia Tiziana Di Salvo Gerry Doyle Maurizio Falanga XiLong Fan Robert D.Ferdman Marco Feroci Federico Fraschetti Duncan K.Galloway Angelo F.Gambino Poshak Gandhi MingYu Ge Bruce Gendre Ramandeep Gill Diego G?tz Christian Gouiffès Paola Grandi Jonathan Granot Manuel Güdel Alexander Heger Craig O.Heinke Jeroen Homan Rosario Iaria Kazushi Iwasawa Luca Izzo Long Ji Peter G.Jonker Jordi José Jelle S.Kaastra Emrah Kalemci Oleg Kargaltsev Nobuyuki Kawai Laurens Keek Stefanie Komossa Ingo Kreykenbohm Lucien Kuiper Devaky Kunneriath Gang Li En-Wei Liang Manuel Linares Francesco Longo FangJun Lu Alexander A.Lutovinov Denys Malyshev Julien Malzac Antonios Manousakis Ian McHardy Missagh Mehdipour YunPeng Men Mariano Méndez Roberto P.Mignani Romana Mikusincova M.Coleman Miller Giovanni Miniutti Christian Motch Joonas Nättilä Emanuele Nardini Torsten Neubert Paul T.O'Brien Mauro Orlandini Julian P.Osborne Luigi Pacciani Stéphane Paltani Maurizio Paolillo Iossif E.Papadakis Biswajit Paul Alberto Pellizzoni Uria Peretz Miguel A.Pérez Torres Emanuele Perinati Chanda Prescod-Weinstein Pablo Reig Alessandro Riggio Jerome Rodriguez Pablo Rodríguez-Gil Patrizia Romano Agata Rózańska Takanori Sakamoto Tuomo Salmi Ruben Salvaterra andrea Sanna andrea Santangelo Tuomas Savolainen Stéphane Schanne Hendrik Schatz LiJing Shao andy Shearer Steven N.Shore Ben W.Stappers Tod E.Strohmayer Valery F.Suleimanov Jirí Svoboda F.-K.Thielemann Francesco Tombesi Diego F.Torres Eleonora Torresi Sara Turriziani andrea Vacchi Stefano Vercellone Jacco Vink Jian-Min Wang JunFeng Wang Anna L.Watts ShanShan Weng Nevin N.Weinberg Peter J.Wheatley Rudy Wijnands Tyrone E.Woods Stan E.Woosley ShaoLin Xiong YuPeng Xu Zhen Yan George Younes WenFei Yu Feng Yuan Luca Zampieri Silvia Zane andrzej A.Zdziarski Shuang-Nan Zhang Shu Zhang Shuo Zhang Xiao Zhang Michael Zingale | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 0 |
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