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| 1 | Early acute kidney injury after liver transplantation: Predisposing factors and clinical implications显示文摘AIM To investigate the additional clinical impact of hepatic ischaemia reperfusion injury(HIRI) on patients sustaining acute kidney injury(AKI) following liver transplantation.METHODS This was a single-centre retrospective study of consecutive adult patients undergoing orthotopic liver transplantation(OLT) between January 2013 and June 2014. Early AKI was identified by measuring serum creatinine at 24 h post OLT(> 1.5 × baseline) or by the use of continuous veno-venous haemofiltration(CVVHF) during the early post-operative period. Patients with and without AKI were compared to identify risk factors associated with this complication. Peak serum aspartate aminotransferase(AST) within 24 h post-OLT was used as a surrogate marker for HIRI and severity was classified as minor(< 1000 IU/L), moderate(1000-5000 IU/L) or severe(> 5000 IU/L). The impact on time to extubation, intensive care length of stay, incidence of chronic renal failure and 90-d mortality were examined firstly for each of the two complications(AKI and HIRI) alone and then as a combined outcome. RESULTS Out of the 116 patients included in the study, 50% developed AKI, 24% required CVVHF and 70% sustainedmoderate or severe HIRI. Median peak AST levels were 1248 IU/L and 2059 IU/L in the No AKI and AKI groups respectively(P = 0.0003). Furthermore, peak serum AST was the only consistent predictor of AKI on multivariate analysis P = 0.02. AKI and HIRI were individually associated with a longer time to extubation, increased length of intensive care unit stay and reduced survival. However, the patients who sustained both AKI and moderate or severe HIRI had a longer median time to extubation(P < 0.001) and intensive care length of stay(P = 0.001) than those with either complication alone. Ninety-day survival in the group sustaining both AKI and moderate or severe HIRI was 89%, compared to 100% in the groups with either or neither complication(P = 0.049). CONCLUSION HIRI has an important role in the development of AKI post-OLT and has a negative impact on patient outcomes, especially when occurring alongside AKI. | Suehana Rahman Susan V Mallett Brian R Davidson | 2017 | World Journal of Hepatology2017，9，18： | 6 |
| 2 | Gastroenterology service in a teaching hospital in rural New Zealand, 1991-2003显示文摘AIM: To retrospectively collect inpatient and outpatient data and to assess the use of endoscopic procedures during the years 1991, 1997 and 2003 to analyse for trends. METHODS: This retrospective survey was conducted in a University-associated Gastroenterology Unit offering secondary and tertiary health care services for a population of approximately 182 000 people in Southern New Zealand. Data collected included patient contacts (inand outpatients), gastroscopic and colonoscopic investigations. RESULTS: We observed a significant increase in the absolute numbers of patient contacts over the years (1991: 2308 vs 1997: 2022 vs 2003: 2783, P < 0.0001) with inflammatory bowel disease, other diseases of the colon, anus and rectum and iron studies related disorders decreasing significantly but liver disease and constipation increasing linearly over time. The use of endoscopy services remained relatively stable but colonoscopic investigations for a positive family history of colorectal cancer increased significantly while more gastroscopies were performed for unexplained anaemia. CONCLUSION: The whole spectrum of gastroenterology contacts was studied. A substantial proportion of colonoscopies and outpatient consultations were undertaken to screen for colorectal cancer. This proportion is likely to grow further. Our fi ndings have implications for the recruitment and training of the next generation of gastroenterologists. | Michael Schultz Andrew Davidson Sarah Donald Bogna Targonska Angus Turnbull Susan Weggery Vicki Livingstone John D Dockerty | 2009 | World Journal of Gastroenterology2009，15，5： | 3 |
| 3 | 维生素对繁殖性能的影响显示文摘 | 蒋正芳 覃矜 Susan Davidson | 2000 | 国外畜牧学(猪与禽)2000，20，5： | 2 |
| 4 | Keys for XML显示文摘 | Peter Buneman Susan Davidson Wenfei Fan | 2002 | Computer Networks2002，39，5： | 1 |
| 5 | Reasoning about keys for XML显示文摘 | Peter Buneman Susan Davidson Wenfei Fan | 2001 | Lecture Notes in Computer Science (LNCS)2001，2397，： | 1 |
| 6 | Vertical partitioning of CO2 production within a temperate forest soil 显示文摘 | Davidson E A Kathleen E Susan E | 2006 | Global Change Biology2006，12，： | 1 |
| 7 | Vertical partitioning of CO2 production within a temperate forest soil显示文摘 | Davidson E A Kathleen E Susan E | 2006 | Global Change Biology2006，12，： | 1 |
| 8 | Specifying Database Transformations in WOL显示文摘 | Susan B Davidson Anthony S Kosky | 1999 | Data Engineering1999，22，： | 1 |
| 9 | Cardiac Hemodynamic and Coronary Angiographic Characteristics of Patients Being Evaluated for Liver Transplantation显示文摘 | Susan D. Tiukinhoy-Laing Joseph S. Rossi Melike Bayram Leonardo De Luca Sameer Gafoor Andres Blei Steven Flamm Charles J. Davidson Mihai Gheorghiade | 2006 | The American Journal of Cardiology2006，，2： | 1 |
| 10 | Review of Polymer Materials for Solar Water Heating Systems显示文摘 | Raman Raghu Mantell Susan Davidson Jane | 2000 | Journal of Solar Energy Engineering2000，122，2： | 1 |
| 11 | Abnormal Uterine Bleeding During the Reproductive Years显示文摘 | Bridget R. Davidson Christina M. DiPiero Kara D. Govoni Susan S. Littleton Jeremy L. Neal | 2012 | Journal of Midwifery & Women?s Health2012，，3： | 1 |
| 12 | Keys for XML 显示文摘 | Buneman Peter Davidson Susan Fan Wen-fei et aJ | 2002 | Computer Networks2002，39，5： | 1 |
| 13 | Vertical partitioning of CO2 production within a temperate forest soil显示文摘 | Davidson E A Kathleen E Susan E | 2006 | Global Change Biology2006，12，： | 1 |
| 14 | Keys for XML显示文摘 | Peter Buneman Susan Davidson Wenfei Fan | 2002 | Computer Networks2002，39，5： | 1 |
| 15 | Topotecan concomitant with primary brachytherapy radiation in patients with cervical carcinoma:a phase I trial显示文摘 | Maria C Bell Susan A Davidson J Michael Mathis | 2001 | Gynecologic Oncology2001，80，2： | 1 |
| 16 | Hypertriglyceridemic Waist Phenotype Predicts Increased Visceral Fat in Subjects With Type 2 Diabetes显示文摘 | Sam Susan Haffner Steven Davidson Michael H D’Agostino Ralph B Feinstein Steven Kondos George Perez Alfonso Mazzone Theodore | 2009 | Diabetes Care2009，，10： | 1 |
| 17 | Carbonic anhydrase(CA Ⅸ) expression,a potential new intrinsic marker of hypoxia: correlations with tumor oxygen measurements and prognosis in locally advanced carcinoma of the cervix 显示文摘 | Juliette A Loneaster Adrian L Harris Susan E Davidson | 2001 | Cancer Res2001，61，17： | 1 |
| 18 | Provenance and Scientific Workflows: Challenges and Opportunities 显示文摘 | Susan B Davidson Juliana Freire | 2008 | Sigmod Conference2008，，： | 1 |
| 19 | A review of polymer materials for solar water heating systems显示文摘 | Raghu Raman Susan Manteli Jane Davidson | 2000 | ASME Journal of Solar Energy2000，122，2： | 1 |
| 20 | Cediranib combined with carboplatin and paclitaxel in patients with metastatic or recurrent cervical cancer (CIRCCa): a randomised, double-blind, placebo-controlled phase 2 trial显示文摘 | R Paul Symonds Charlie Gourley Susan Davidson Karen Carty Elaine McCartney Debbie Rai Susana Banerjee David Jackson Rosemary Lord Mary McCormack Emma Hudson Nicholas Reed Maxine Flubacher Petra Jankowska Melanie Powell Caroline Dive Catharine M L West Jam | 2015 | The Lancet Oncology2015，，15： | 1 |
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