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| 1 | Eradication rate and histological changes after Helicobacter pylori eradication treatment in gastric cancer patients following subtotal gastrectomy显示文摘AIM: To investigate the eradication rate and histological changes after Helicobacter pylori(H. pylori) eradication treatment following subtotal gastrectomy for gastric cancer.METHODS: A total of 610 patients with H. pylori infection who had undergone surgery for either early or advanced gastric adenocarcinoma between May 2004 and December 2010 were retrospectively studied. A total of 584 patients with proven H. pylori infection after surgery for gastric cancer were enrolled in this study. Patients received a seven day standard triple regimen as first-line therapy and a 10 d bismuthcontaining quadruple regimen as second-line therapy in cases of eradication failure. The patients underwent an esophagogastroduodenoscopy(EGD) between six and 12 mo after surgery, followed by annual EGDs. A further EGD was conducted 12 mo after confirming the result of the eradication and the histological changes. A gastric biopsy specimen for histological examination and Campylobacter-like organism testing was obtained from the lesser and greater curvature of the corpus of the remnant stomach. Histological changes in the gastric mucosa were assessed using the updated Sydney system before eradication therapy and at follow-up after 12 mo.RESULTS: Eradication rates with the first-line and second-line therapies were 78.4%(458/584) and 90%(36/40), respectively, by intention-to-treat analysis and 85.3%(458/530) and 92.3%(36/39), respectively, by per-protocol analysis. The univariate and multivariate analyses revealed that Billroth Ⅱ surgery was an independent factor predictive of eradication success in the eradication success group(OR = 1.53, 95%CI: 1.41-1.65, P = 0.021). The atrophy and intestinal metaplasia(IM) scores 12 mo after eradication were significantly lower in the eradication success group than in the eradication failure group(0.25 ± 0.04 vs 0.47 ± 0.12, P = 0.023; 0.27 ± 0.04 vs 0.51 ± 0.12, P = 0.015, respectively). The atrophy and IM scores 12 mo after successful eradication were significantly lower in the Billroth Ⅱ group than in the Billroth I group(0.13 ± 0.09 vs 0.31 ± 0.12, P = 0.029; 0.32 ± 0.24 vs 0.37 ± 0.13, P = 0.034, respectively).CONCLUSION: Patients with H. pylori following subtotal gastrectomy had a similar eradication rate to patients with an intact stomach. H. pylori eradication is recommended after subtotal gastrectomy. | Jae Jin Hwang Dong Ho Lee Kyu Keun Kang Ae-Ra Lee Hyuk Yoon Cheol Min Shin Young Soo Park Nayoung Kim | 2015 | World Journal of Gastroenterology2015，21，13： | 5 |
| 2 | Association Between Metabolic Syndrome and Helicobacter pylori Infection Diagnosed by Histologic Status and Serological Status显示文摘 | Dong Wook Shin Hyuk Tae Kwon Jung Min Kang Jin Ho Park Ho Chun Choi Min Seon Park Sang Min Park Ki Young Son BeLong Cho | 2012 | Journal of Clinical Gastroenterology2012，，10： | 3 |
| 3 | The efficacy of hybrid therapy as first‐line regimen for H elicobacter pylori infection compared with sequential therapy显示文摘 | Dong Hyun Oh Dong Ho Lee Kyu Keun Kang Young Soo Park Cheol Min Shin Nayoung Kim Hyuk Yoon Jin Hyeok Hwang Sook Hyang Jeoung Jin Wook Kim Eun Sun Jang Hyun Chae Jung | 2014 | J Gastroenterol Hepatol2014，，6： | 3 |
| 4 | Laparoscopic-Assisted Versus Open Complete Mesocolic Excision and Central Vascular Ligation for Right-Sided Colon Cancer显示文摘 | Sung Uk Bae Avanish P. Saklani Dae Ro Lim Dong Wook Kim Hyuk Hur Byung Soh Min Seung Hyuk Baik Kang Young Lee Nam Kyu Kim | 2014 | Annals of Surgical Oncology2014，，7： | 2 |
| 5 | Meta‐analysis: Is sequential therapy superior to standard triple therapy for H elicobacter pylori infection in A sian adults?显示文摘 | Hyuk Yoon Dong Ho Lee Nayoung Kim Young Soo Park Cheol Min Shin Kyu Keun Kang Dong Hyun Oh Dong Kee Jang Jun‐Won Chung | 2013 | J Gastroenterol Hepatol2013，，12： | 2 |
| 6 | Occult gastric cancer with distant metastasis proven by random gastric biopsy显示文摘Krukenberg tumor, a rare metastatic ovarian tumor arising from gastrointestinal adenocarcinoma mainly, tends to occur in premenopausal females. Finding the origin of a Krukenberg tumor is crucial for determining prognosis. In Eastern countries, the most common origin of Krukenberg tumor is stomach cancer, which is generally diagnosed via endoscopic biopsy to investigate an abnormal mucosal lesion. Here, we describe a case of huge adnexal mass in a 33-year-old woman who presented with abdominal distension. Two independent endoscopic examinations performed by experts in two tertiary university hospitals revealed no abnormal mucosal lesion. The patient was diagnosed with a Krukenberg tumor according to findings from random endoscopic biopsies taken from normal-looking gastric mucosa in our hospital. It is very rare to be diagnosed via a random biopsy in cases where three well-trained endoscopists had not found any mucosal lesion previously. Thus, in this case, random biopsy was helpful in finding the origin of a Krukenberg tumor. | Sang Hyuk Lee Kyu-Hyoung Lim Seo-Young Song Hui-Young Lee Sung Chul Park Chang Don Kang Sung Joon Lee Dong Wook Choi Sung Bae Park Young-Joon Ryu | 2016 | World Journal of Gastroenterology2016，22，16： | 2 |
| 7 | Laparoendoscopic Single-site Repair of Bladder Rupture Using a Home-made Single-port Device: Initial Experience of Treatment for a Traumatic Intraperitoneal Bladder Rupture显示文摘 | Joo Yong Lee Dong Hyuk Kang Seung Wook Lee | 2012 | Surgical Laparoscopy, Endoscopy & Percutaneous Techniques2012，，3： | 1 |
| 8 | Helicobacter pylori eradication with moxifloxacin-containing therapy following failed first-line therapies in South korea显示文摘AIM:To investigate moxifloxacin-containing triple therapy as second-line treatment for Helicobacter pylori(H.pylori)infection following failed first-line treatment.METHODS:The sample included 312 patients for whom first-line treatment failed between January 2008and May 2013;27 patients were excluded,and a total of 285 patients received 7-or 14-d moxifloxacincontaining triple therapy as second-line treatment for H.pylori infection.First line regimens included 7-d standard triple(n=172),10-d bismuth-containing quadruple(n=28),14-d concomitant(n=37),or14-d sequential(n=48)therapy.H.pylori status was evaluated using 13C-urea breath testing 4 wk later,aftercompletion of the treatment.The primary outcome was the H.pylori eradication rate analyzed using intentionto-treat(ITT)and per protocol(PP)analyses.The secondary outcome was the occurrence of serious adverse events.Demographic and clinical factors were analyzed using Student’s t-tests and Pearson’sχ2 tests according to first-and second-line regimens.A P value of less than 0.05 was considered statistically significant.RESULTS:The eradication rate of moxifloxacincontaining triple therapy was 68.4%(ITT;95%CI:62.8-73.5)and 73.9%(PP;95%CI:68.3-78.8).The eradication rate was significantly higher with 14 d compared to 7 d of treatment(77.5%vs 62.5%,P=0.017).Peptic ulcer patients had a higher eradication rate than the patients without ulcers(82.9%vs 70.6%,P=0.046).The demographic and clinical characteristics were not significantly different between the groups according to first-line therapies.ITT and PP analyses of the moxifloxacin-containing triple therapy indicated the following eradication rates:70.9%(95%CI:63.8-77.2)and 77.2%(95%CI:70.1-83.1)for standard triple;67.9%(95%CI:51.5-84.2)and 67.9%(95%CI:51.5-84.2)for bismuth-containing quadruple;60.4%(95%CI:46.3-73.0)and 70.7%(95%CI:54.0-80.9)for sequential;and 67.6%(95%CI:51.5-80.4)and67.6%(95%CI:51.5-80.4)for concomitant therapy.There were no statistically significant differences in the efficacy of the first-line regimens(P=0.492).The most common adverse event was diarrhea.There were no serious adverse events and no significant differences in the frequency of side effects between the first-and second-line regimens(28.7%vs 26.1%,respectively).CONCLUSION:Moxifloxacin-containing triple therapy as second-line treatment resulted in low eradication rates.There were no differences in the efficacy between the first-line regimens in South Korea. | Kyu Keun Kang Dong Ho Lee Dong Hyun Oh Hyuk Yoon Cheol Min Shin Young Soo Park Nayoung Kim Hyun Chae Jung | 2014 | World Journal of Gastroenterology2014，20，22： | 1 |
| 9 | Correlation of photoluminescence of (Y, Ln)VO 4 :Eu 3+ (Ln=Gd and La) phosphors with their crystal structures显示文摘 | Jong Hyuk Kang Won Bin Im Dong Chin Lee Jin Young Kim Duk Young Jeon Yun Chan Kang Kyeong Youl Jung | 2005 | Solid State Communications2005，，10： | 1 |
| 10 | Cytotoxic effects of triterpenoid saponins from Androsace umbellata against multidrug resistance (MDR) and non-MDR cells显示文摘 | Jong Hyuk Park Jong Hwan Kwak Ja Heouk Khoo Sung-Hoon Park Dae Up Kim Dong Mun Ha Sang Un Choi Se Chan Kang Ok Pyo Zee | 2010 | Archives of Pharmacal Research2010，，8： | 1 |
| 11 | Effects of Noscarna? on hypertrophic scarring in the rabbit ear model: Histopathological aspects显示文摘 | Dong Won Lee Sae Kwang Ku Hyuk Jun Cho Jeong Hwan Kim Tran Tuan Hiep Sang Duk Han Bo Gyun Kim Min Kyung Kang Eui Seon Do Joon Ho Jun Sun Woo Jang Mi-Won Son Young Taek Sohn Han-Gon Choi Chul Soon Yong Jong Oh Kim | 2012 | Archives of Pharmacal Research2012，，11： | 1 |
| 12 | Achieving recommended low density lipoprotein cholesterol goals and the factors associated with target achievement of hypercholesterolemia patients with rosuvastatin in primary care显示文摘 | Jung Ah Lee Sung Sunwoo Young Sik Kim Han Jin Oh Hee-Cheol Kang Kyung-Chae Park Dong Hyuk Sin Sang Yeoup Lee Yun Jun Yang Byung Yeon Yu Chul-Min Kim | 2013 | Current Medical Research & Opinion2013，，： | 1 |
| 13 | The efficacy of frontline platinum-based combination chemotherapy in advanced adenocarcinoma of the ampulla of Vater显示文摘 | Seung Tae Kim Jeeyun Lee Kyu Taek Lee Jong Kyun Lee Kwang Hyuk Lee Seong-Ho Choi Jin-Seok Heo Dong Wook Choi Se Hoon Park Joon Oh Park Ho Yeong Lim Young Suk Park Won Ki Kang | 2010 | Medical Oncology2010，，4： | 1 |
| 14 | Electrochemical response of ZrO 2 -incorporated oxide layer on AZ91 Mg alloy processed by plasma electrolytic oxidation显示文摘 | Kang Min Lee Ki Ryong Shin Seung Namgung Bongyoung Yoo Dong Hyuk Shin | 2011 | Surface & Coatings Technology2011，，13： | 1 |
| 15 | Critical factors to inhibit water-splitting side reaction in carbon-based electrode materials for zinc metal anodes显示文摘Zinc metal anodes(ZMA)have high theoretical capacities(820 mAh g−1 and 5855 mAh cm−3)and redox potential(−0.76 V vs.standard hydrogen electrode),similar to the electrochemical voltage window of the hydrogen evolution reaction(HER)in a mild acidic electrolyte system,facilitating aqueous zinc batteries competitive in next-generation energy storage devices.However,the HER and byproduct formation effectuated by water-splitting deteriorate the electrochemical performance of ZMA,limiting their application.In this study,a key factor in promoting the HER in carbon-based electrode materials(CEMs),which can provide a larger active surface area and guide uniform zinc metal deposition,was investigated using a series of threedimensional structured templating carbon electrodes(3D-TCEs)with different local graphitic orderings,pore structures,and surface properties.The ultramicropores of CEMs are the determining critical factors in initiating HER and clogging active surfaces by Zn(OH)2 byproduct formation,through a systematic comparative study based on the 3D-TCE series samples.When the 3D-TCEs had a proper graphitic structure with few ultramicropores,they showed highly stable cycling performances over 2000 cycles with average Coulombic efficiencies of≥99%.These results suggest that a well-designed CEM can lead to high-performance ZMA in aqueous zinc batteries. | Dong Hyuk Kang Eunji Lee Beom Sik Youn Son Ha Jong Chan Hyun Juhee Yoon Dawon Jang Kyoung Sun Kim Hyungsub Kim Sang Moon Lee Sungho Lee Hyoung-Joon Jin Hyung-Kyu Lim Young Soo Yun | 2022 | Carbon Energy2022，4，6： | 0 |
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