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| 1 | Simultaneous determination of ten taste and odor compounds in drinking water by solid-phase microextraction combined with gas chromatography-mass spectrometry显示文摘Taste and odor(T&O)problems in drinking water frequently occur because of many compounds present in the water,of which trans-1,10-dimethyl-trans-9-decalol(geosmin)and 2-methylisoborneol(MIB)are well-known.In this study,a fast and efective method was established for simultaneous determination of 10 T&O compounds,including geosmin,MIB,2,4,6-trichloroanisole(TCA),2-methylbenzofuran,2-isopropyl-3-methoxypyrazine(IPMP),2-isobutyl-3-methoxypyrazine(IBMP),cis-3-hexenyl acetate,trans,trans-2,4-heptadienal,trans,cis-2,6-nonadienal,and trans-2-decenal in water samples by headspace solid-phase microextraction(SPME)coupled with gas chromatography-mass spectrometry.An orthogonal array experimental design was used to optimize the efects of SPME fiber,extraction temperature,stirring rate,NaCl content,extraction time,and desorption time.The limits of detection ranged from 0.1 to 73 ng/L were lower than or close to the odor threshold concentrations(OTCs).All the 10 T&O compounds were detected in the 14 water samples including surface water,treatment process water and tap water,taken from a waterworks in Lianyungang City,China.MIB and geosmin were detected in most samples at low concentration.Six T&O compounds(IPMP,IBMP,trans,cis-2,6-nonadienal,2-methylbenzofuran,trans-2-decenal,and TCA)were efectively decreased in water treatment process(sedimentation and filtration)that is diferent from cis-3-hexenyl acetate,MIB and geosmin.It is noted that the TCA concentrations at 15.9–122.3 ng/L and the trans,cis-2,6-nonadienal concentrations at 79.9–190.1 ng/L were over 10 times higher than their OTCs in tap water.The variation of the analytes in the all water samples,especially distribution system indicated that distribution system cannot be ignored as a T&O compounds source. | Xichao Chen Qian Luo Shengguang Yuan Zi Wei Hanwen Song Donghong Wang Zijian Wang | 2013 | Journal of Environmental Sciences2013，25，11： | 21 |
| 2 | The Arabidopsis PRCl-like ring-finger proteins are necessary for repression of embryonic traits during vegetative growth显示文摘Polycomb 组基因在维护起关键作用 transcriptionally 为在动物和植物的合适的房间区别的基因的 silenced 状态。当时 polycomb 的部件压抑的 complex2 (PRC2 ) evolutionarily 被保存,他们的功能广泛地在植物被学习, PRC1 在动物和植物之间更加不同,并且它在植物的功能是不好迄今为止描述了。以前的研究作为动物 PRC1 子单元 RING1 的相当或相同事物识别了 Arabidopsis AtRING1a 和 AtRING1b。这里,我们证明 Atring1a Atring1b 双异种在植物的生长期间展出胚胎的特点的 derepression。因此,几关键规章的基因在 embryogenesis 包含了,干细胞活动宫外地在异种被表示。而且,我们证明变异的显型和规章的基因的增加的表示被 PRC2 变异的 clf 提高。最后,我们显示出那动物 PRC1 子单元戒指手指蛋白质 BMI1, AtBMI1a, AtBMI1b 和 AtBMI1c 的三个相当或相同事物,罐头与 AtRING1a 或 AtRING1b 绑,并且另外, AtBMI1c 能与 LHP1 绑。Atbmi1a Atbmi1b 双异种显示出类似于 Atring1a Atring1b 双异种的胚胎的特点的 derepression。有趣地, AtBMI1a, AtBMI1b 和 AtBMI1c 的表示层次在 Atring1a Atring1b 异种被提高,那些在 Atbmi1a Atbmi1b 异种 AtBMI1c, AtRING1a 和 AtRING1b 被提高,建议自我规章的反馈机制。一起拿,我们的结果为合适的体的生长在胚胎的特点和规章的基因的稳定的压抑照亮象 PRC1 一样戒指手指部件的关键功能。 | Donghong Chen Anne Molitor Chunlin Liu Wen-Hui Shen | 2010 | Cell Research2010，20，12： | 19 |
| 3 | Huangjing(Polygonati rhizoma)is an emerging crop with great potential to fight chronic and hidden hunger显示文摘According to an annual flagship report produced jointly by the FAO and several other organizations,almost 690 million people,or 8.9 percent of the world’s population,were still suffering from chronic hunger in 2019(FAO et al.,2020). | Donghong Chen Zhigang Han Jinping Si | 2021 | Science China(Life Sciences)2021，64，9： | 10 |
| 4 | Occurrence and removal of organic micropollutants in the treatment of landfill leachate by combined anaerobic-membrane bioreactor technology显示文摘Organic micropollutants,with high toxicity and environmental concern,are present in the landfill leachate at much lower levels than total organic constituents (chemical oxygen demand (COD),biochemical oxygen demand (BOD),or total organic carbon (TOC)),and few has been known for their behaviors in different treatment processes.In this study,occurrence and removal of 17 organochlorine pesticides (OCPs),16 polycyclic aromatic hydrocarbons (PAHs),and technical 4-nonylphenol (4-NP) in landfill leachate in a combined anaerobic-membrane bioreactor (MBR) were investigated.Chemical analyses were performed in leachates sampled from different treatment processes,using solid-phase extraction and gas chromatography with electron capture detector and mass spectrometry.Concentrations of OCPs,PAHs,and 4-NP in the raw leachate were detected within the range from ND (not detected) to 595.2 ng/L,which were as low as only 10-7-10-5 percentage of TOC (at the concentration of 2,962 mg/L).The removal of 4-NP was mainly established in the MBR process,in agreement with removals of COD,BOD,and TOC.However,the removals of OCPs and PAHs were different,mainly achieved in the anaerobic process.High removal effciencies of both total organic constituents and organic micropollutants could be achieved by the combined anaerobic-MBR technology.The removal effciencies of total organic constituents were in the order of BOD (99%) > COD (89%) > TOC (87%),whereas the removal effciencies of investigated organic micropollutants were as follows: OCPs (94%) > 4-NP (77%) > PAHs (59%). | Yiping XU Zijian WANG | 2008 | Journal of Environmental Sciences2008，20，11： | 7 |
| 5 | Relation Classification via Sequence Features and Bi-Directional LSTMs显示文摘Structure features need complicated pre-processing, and are probably domain-dependent. To reduce time cost of pre-processing, we propose a novel neural network architecture which is a bi-directional long-short-term-memory recurrent-neural-network(Bi-LSTM-RNN) model based on low-cost sequence features such as words and part-of-speech(POS) tags, to classify the relation of two entities. First, this model performs bi-directional recurrent computation along the tokens of sentences. Then, the sequence is divided into five parts and standard pooling functions are applied over the token representations of each part. Finally, the token representations are concatenated and fed into a softmax layer for relation classification. We evaluate our model on two standard benchmark datasets in different domains, namely Sem Eval-2010 Task 8 and Bio NLP-ST 2016 Task BB3. In Sem Eval-2010 Task 8, the performance of our model matches those of the state-of-the-art models, achieving 83.0% in F1. In Bio NLP-ST 2016 Task BB3, our model obtains F_1 51.3% which is comparable with that of the best system. Moreover, we find that the context between two target entities plays an important role in relation classification and it can be a replacement of the shortest dependency path. | REN Yuanfang TENG Chong LI Fei CHEN Bo JI Donghong | 2017 | Wuhan University Journal of Natural Sciences2017，22，6： | 6 |
| 6 | First light of the 1.8-m solar telescope–CLST显示文摘Large-aperture solar telescopes play an important role in solar observations and research,and require high temporal and spatial resolution[1].To solve some fundamental problems such as the solar dynamo,coronal heating,and the triggering of major solar eruptions,the spatial resolution for solar-atmosphere observation should reach at least 0.1 arcsec[2]. | ChangHui Rao NaiTing Gu XueJun Rao Cheng Li LanQiang Zhang JinLong Huang Lin Kong Ming Zhang YunTao Cheng Yi Pu Hua Bao YouMing Guo YangYi Liu JinSheng Yang LiBo Zhong ChangJun Wang Kai Fang XiaoJun Zhang DongHong Chen Cheng Wang XinLong Fan ZhiWu Yan KeLe Chen XiYa Wei Lei Zhu Hong Liu YongJian Wan Hao Xian WenLi Ma | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，10： | 6 |
| 7 | Multiple action sites of ultrasound on Escherichia coli and Staphylococcus aureus显示文摘Ultrasound,is thought to a potential non-thermal sterilization technology in food industry.However,the exact mechanisms underlying microbial inactivation by ultrasound still remain obscure.In this study,the action modes of ultrasound on both Gram-negative and Gram-positive microorganisms were estimated.From colony results,ultrasound acted as an irreversible effect on both Eshcerichia coli and Staphylococcus aureus without sublethal injury.The result in this study also showed that a proportion of bacteria subpopulation suffered from serious damage of intracellular components(e.g.DNA and enzymes)but with intact cell envelopes.We speculated that the inactivated effects of ultrasound on microbes might more than simply completed disruption of cell exteriors.Those microbial cells who had not enter the valid area of ultrasonic cavitation might be injected with free radicals produced by ultrasound and experienced interior injury with intact exterior structure,and others who were in close proximity to the ultrasonic wave field would be immediately and completely disrupted into debris by high power mechanic forces.These findings here try to provide extension for the inactivation mechanisms of ultrasound on microorganisms. | Xinyu Liao Jiao Li Yuanjie Suo Shiguo Chen Xingqian Ye Donghong Liu Tian Ding | 2018 | Food Science and Human Wellness2018，7，1： | 6 |
| 8 | SVD-TLS extending Prony algorithm for extracting UWB radar target feature显示文摘A new method, SVD-TLS extending Prony algorithm, is introduced for extracting UWB radar target features. The method is a modified classical Prony method based on singular value decomposition and total least squares that can improve robust for spectrum estimation. Simulation results show that poles and residuum of target echo can be extracted effectively using this method, and at the same time, random noises can be restrained to some degree. It is applicable for target feature extraction such as UWB radar or other high resolution range radars. | Liu Donghong Hu Wenlong Chen Zhijie | 2008 | Journal of Systems Engineering and Electronics2008，19，2： | 4 |
| 9 | Preparation and phase change performance of Na_2HPO_4·12H_2O@poly(lactic acid) capsules for thermal energy storage显示文摘Micro-encapsulated phase-change materials(micro PCMs) with Na_2 HPO_4·12 H_2 O encapsulated in poly(lactic acid)(PLA) shell were prepared by a solvent evaporation–precipitation method that involves the use of a coaxial needle. The effects of PLA concentration, stirring speed, injection rate of core and shell solutions, and polyvinyl alcohol(PVA) concentration on phase change properties were investigated. The thermal properties of microP CMs were characterized by differential scanning calorimetry(DSC). The capsules prepared under the optimal conditions are about 2 mm in diameter and show a latent heat of up to 122.2 J·g^(-1). | Na Fan Lang Chen Guoyong Xie Donghong Yin Chak-Tong Au Shuangfeng Yin | 2019 | Chinese Journal of Chemical Engineering2019，27，3： | 4 |
| 10 | Thermal damage analysis of aircraft composite laminate suffered from lightning swept stroke and arc propagation显示文摘Lightning strike is a complicated process involving multi-field coupling.In order to investigate the thermal damage mechanism of carbon fiber reinforced composites subject to lightning swept stroke,a complete numerical method is presented.Numerical model of lightning discharge is established based on Magneto Hydro Dynamics(MHD)and calculated by FLUENT secondary development technology.Considering aerodynamic flow effect,channel formation and evolution process during lightning discharge is analyzed for lightning current waveform A.Thermal-electric Coupling model is presented according to Radial Basis Function(RBF)interpolation theory,which is implemented by compiling program to make lightning current and heat energy inject into composite laminate.Consequently,damage mechanism of composite laminate under lightning swept stroke is studied based on the coupled numerical model and element deletion method.Ablation damage morphology of composite laminate is analyzed to understand plasma expansion and reattachment in arc root.The results show that aerodynamic flow makes the lightning channel move fast and composite laminate is deteriorated due to thermal damage. | Xiangteng MA Fusheng WANG Han CHEN Donghong WANG Bin XU | 2020 | Chinese Journal of Aeronautics2020，33，4： | 3 |
| 11 | Concentration of circulating microparticles:a new biomarker of acute heart failure after cardiac surgery with cardiopulmonary bypass显示文摘Acute heart failure(AHF)is a severe complication after cardiac surgery with cardiopulmonary bypass(CPB).Although some AHF biomarkers have been used in clinic,they have limitations when applied in the prediction and diagnosis of AHF after cardiac surgery with CPB,and there are still no effective and specific biomarkers.We and other researchers have shown that circulating microparticles(MPs)increased in a variety of cardiovascular diseases.However,whether the concentration of circulating MPs could be a new biomarker for AHF after cardiac surgery remains unknown.Here,90 patients undergoing cardiac surgery with CPB and 45 healthy subjects were enrolled.Patients were assigned into AHF(n=14)or non-AHF(n=76)group according to the diagnosis criteria of AHF.The concentrations of circulating MPs were determined before,as well as 12 h and 3 days after operation with nanoparticle tracking analysis technique.MPs concentrations in patients before surgery were significantly higher than those of healthy subjects.Plasma levels of MPs were significantly elevated at 12 h after surgery in patients with AHF,but not in those without AHF,and the circulating MPs concentrations at 12 h after surgery were higher in AHF group compared with non-AHF group.Logistic regression analysis indicated that MPs concentration at postoperative 12 h was an independent risk factor for AHF.The area under receiver operating characteristic curve for MPs concentration at postoperative 12 h was 0.87 and the best cut-off value is 5.20×10~8 particles mL~(–1)with a sensitivity of 93%and a specificity of 70%.These data suggested that the concentration of circulating MPs might be a new biomarker for the occurrence of AHF after cardiac surgery with CPB. | Yuquan Li Haoxiang Yuan Caiyun Chen Chao Chen Jian Ma Yating Chen Yan Li Yupeng Jian Donghong Liu Zhijun Ou Jingsong Ou | 2021 | Science China(Life Sciences)2021，64，1： | 3 |
| 12 | Efficacy and safety of high-dose esomeprazole–amoxicillin dual therapy for Helicobacter pylori rescue treatment:a multicenter,prospective,randomized,controlled trial显示文摘Background:High-dose dual therapy(HDDT)with proton pump inhibitors(PPIs)and amoxicillin has attracted widespread attention due to its favorable efficacy in eradicating Helicobacter pylori(H.pylori).This study aimed to compare the efficacy and safety of high-dose PPI-amoxicillin dual therapy and bismuth-containing quadruple therapy for H.pylori rescue treatment.Methods:This was a prospective,randomized,multicenter,non-inferiority trial.Patients recruited from eight centers who had failed previous treatment were randomly(1:1)allocated to two eradication groups:HDDT(esomeprazole 40 mg and amoxicillin 1000 mg three times daily;theHDDTgroup)and bismuth-containing quadruple therapy(esomeprazole 40 mg,bismuth potassium citrate 220 mg,and furazolidone 100 mg twice daily,combined with tetracycline 500 mg three times daily;the tetracycline,furazolidone,esomeprazole,and bismuth[TFEB]group)for 14 days.The primary endpoint was the H.pylori eradication rate.The secondary endpoints were adverse effects,symptom improvement rates,and patient compliance.Results:A total of 658 patients who met the criteria were enrolled in this study.The HDDT group achieved eradication rates of 75.4%(248/329),81.0%(248/306),and 81.3%(248/305)asdetermined by the intention-to-treat(ITT),modified intention-totreat(MITT),and per-protocol(PP)analyses,respectively.The eradication rates were similar to those in the TFEB group:78.1%(257/329),84.2%(257/305),and 85.1%(257/302).The lower 95%confidence interval boundary(9.19%in the ITT analysis,9.21%in the MITT analysis,and9.73%in the PP analysis)was greater than the predefined non-inferiority margin of10%,establishing a non-inferiority of the HDDT group vs.the TFEB group.The incidence of adverse events in the HDDT group was significantly lower than that in the TFEB group(11.1%vs.26.8%,P<0.001).Symptom improvement rates and patients’compliance were similar between the two groups.Conclusions:Fourteen-day HDDT is non-inferior to bismuth-containing quadruple therapy,with fewer adverse effects and good treatment compliance,suggesting HDDT as an alternative for H.pylori rescue treatment in the local region.Trial registration:Clinicaltrials.gov,NCT04678492. | Hanxin Bi Xingxing Chen Yuxin Chen Xin Zhao Shasha Wang Jiehong Wang Ting Lyu Shuang Han Tao Lin Mingquan Li Donghong Yuan Junye Liu Yongquan Shi | 2022 | Chinese Medical Journal2022，，14： | 3 |
| 13 | Homocysteine activates vascular smooth muscle cells by DNA demethylation of platelet-derived growth factor in endothelial cells显示文摘 | Donghong Zhang Yequn Chen Xina Xie Jianlan Liu Qingjie Wang Wei Kong Yi Zhu | 2012 | Journal of Molecular and Cellular Cardiology2012，，4： | 3 |
| 14 | Effect of UV-C treatments on phenolic compounds and antioxidant capacity of minimally processed Satsuma mandarin during refrigerated storage显示文摘 | Yan Shen Yujing Sun Liping Qiao Jianchu Chen Donghong Liu Xingqian Ye | 2013 | Postharvest Biology and Technology2013，，： | 2 |
| 15 | BioTSA: Annotating Token Semantic Association to Support Biomedical Text Mining显示文摘Corpus is a kind of important resource for knowledge acquisition in the natural language processing(NLP). However, up to now, in the biomedical domain comparatively fewer corpus focus on semantic association among all tokens in a sentence. We proposed an annotation scheme based on feature structure theory for enriching biomedical domain corpora with token semantic association(TSA). There are 227 documents of the Bio NLP GE ST training data annotated to form TSA corpus in which each annotated item shows a token semantic association that appears as a triple. The annotation of token semantic association has the potential to significantly advance biomedical text mining by providing rich token semantic information for NLP systems especially for the sophisticated IE systems, such as bio-event extraction. | WEI Xiaomei HUANG Sixing CHEN Bo JI Donghong | 2015 | Wuhan University Journal of Natural Sciences2015，20，2： | 2 |
| 16 | Semantic Relation Annotation for Biomedical Text Mining Based on Recursive Directed Graph显示文摘In this paper we propose a novel model 'recursive directed graph' based on feature structure, and apply it to represent the semantic relations of postpositive attributive structures in biomedical texts. The usages of postpositive attributive are complex and variable, especially three categories: present participle phrase, past participle phrase, and preposition phrase as postpositive attributive, which always bring the difficulties of automatic parsing. We summarize these categories and annotate the semantic information. Compared with dependency structure, feature structure, being recursive directed graph, enhances semantic information extraction in biomedical field. The annotation results show that recursive directed graph is more suitable to extract complex semantic relations for biomedical text mining. | CHEN Bo Lü Chen WEI Xiaomei JI Donghong | 2015 | Wuhan University Journal of Natural Sciences2015，20，2： | 2 |
| 17 | EFFECT OF COOKING STYLES ON THE LIPID OXIDATION AND FATTY ACID COMPOSITION OF GRASS CARP ( CTENOPHARYNYODON IDELLUS ) FILLET显示文摘 | JINJIE ZHANG DAN WU DONGHONG LIU ZHONGXIANG FANG JIANCHU CHEN YAQIN HU XINGQIAN YE | 2012 | Journal of Food Biochemistry2012，，2： | 2 |
| 18 | Phenolic compounds and antioxidant capacities of bayberry juices显示文摘 | Zhongxiang Fang Yuhuan Zhang Yuan Lü Guangpeng Ma Jianchu Chen Donghong Liu Xingqian Ye | 2008 | Food Chemistry2008，，4： | 2 |
| 19 | Biological mechanism study of meditation and its application in mental disorders显示文摘In recent years,research on meditation as an important alternative therapy has developed rapidly and been widely applied in clinical medicine.Mechanism studies of meditation have also developed progressively,showing that meditation has great impact on brain structure and function,and epigenetic and telomere regulation.In line with this,the application of meditation has gradually been expanded to mental illness,most often applied for major depressive disorders and substance-related and addictive disorders.The focus of this paper is to illustrate the biological mechanisms of meditation and its application in mental disorders. | Hui Shen Meijuan Chen Donghong Cui | 2020 | General Psychiatry2020，33，4： | 2 |
| 20 | Biocontrol of blue and gray mold diseases of pear fruit by integration of antagonistic yeast with salicylic acid 显示文摘 | Ting Yu Jishuang Chen Rongle Chen Bin Huang Donghong Liu Xiaodong Zheng | 2007 | International Journal of Food Microbiology2007，116，3： | 1 |
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