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| 1 | Exogenous plant MIR168a specifically targets mammalian LDLRAPI: evidence of cross-kingdom regulation by microRNA显示文摘 | Lin Zhang Dongxia Hou Xi Chen Donghai Li Lingyun Zhu Yuj ing Zhang Jing Li Zhen Bian Xiangying Liang Xing Cai Yuan Yin Cheng Wang Tianfu Zhang Dihan Zhu Dianmu Zhang Jie Xu Qun Chen Yi Ba Jing Liu Qiang Wang Jianqun Chen Jin Wang Meng Wang Qipeng Zhang Junfeng Zhang Ke Zen Chen-Yu Zhang | 2012 | Cell Research2012，22，1： | 155 |
| 2 | Honeysuckle-encoded atypical microRNA2911 directly Largets influenza A viruses显示文摘 | Zhen Zhou Xihan Li Jinxiong Liu Lei Dong Qun Chen Jialing Liu Huihui Kongt Qianyi Zhang Xian Qi Dongxia Hou Lin Zhang Guoquan Zhang Yuchen Liu Yujing Zhang Jing Li Jin Wang Xi Chen Hua Wang Junfeng Zhang Hualan Chen Ke Zen Chen-Yu Zhang | 2015 | Cell Research2015，25，1： | 104 |
| 3 | An Accurate and Real-time Method of Self-blast Glass Insulator Location Based on Faster R-CNN and U-net with Aerial Images显示文摘This paper proposes a new deep learning framework for the location of broken insulators(in particular the self-blast glass insulator)in aerial images.We address the broken insulators location problem in a low signal-noise-ratio(SNR)setting.We deal with two modules:1)object detection based on Faster R-CNN,and 2)classification of pixels based on U-net.For the first time,our paper combines the above two modules.This combination is motivated as follows:Faster R-CNN is used to improve SNR,while the U-net is used for classification of pixels.A diverse aerial image set measured by a power grid in China is tested to validate the proposed approach.Furthermore,a comparison is made among different methods and the result shows that our approach is accurate in real time. | Zenan Ling Dongxia Zhang Robert C.Qiu Zhijian Jin Yuhang Zhang Xing He Haichun Liu | 2019 | CSEE Journal of Power and Energy Systems2019，5，4： | 22 |
| 4 | Charge Structure of a Summer Thunderstorm in North China:Simulation Using a Regional Atmospheric Model System显示文摘Electrification and simple discharge schemes are coupled into a 3D Regional Atmospheric Model System(RAMS) as microphysical parameterizations, in accordance with electrical experiment results. The dynamics, microphysics, and electrification components are fully integrated into the RAMS model, and the inductive and non-inductive electrification mechanisms are considered in the charging process. The results indicate that the thunderstorm mainly had a normal tripole charge structure.The simulated charge structure and lightning frequency are basically consistent with observations of the lightning radiation source distribution. The non-inductive charging mechanism contributed to the electrification during the whole lifetime of the thunderstorm, while the inductive electrification mechanism played a significant role in the development period and the mature stage when the electric field reached a large value. The charge structure in the convective region and the rearward region are analyzed, showing that the charge density in the convective region was double that in the rearward region. | LIU Dongxia QIE Xiushu PENG Liang LI Wanli | 2014 | Advances in Atmospheric Sciences2014，31，5： | 16 |
| 5 | Laser performance of the SG-Ⅲ laser facility显示文摘SG-Ⅲ laser facility is now the largest laser driver for inertial confinement fusion research in China. The whole laser facility can deliver 180 kJ energy and 60 TW power ultraviolet laser onto target, with power balance better than 10%.We review the laser system and introduce the SG-Ⅲ laser performance here. | Wanguo Zheng Xiaofeng Wei Qihua Zhu Feng Jing Dongxia Hu Jingqin Su Kuixing Zheng Xiaodong Yuan Hai Zhou Wanjun Dai Wei Zhou Fang Wang Dangpeng Xu Xudong Xie Bin Feng Zhitao Peng Liangfu Guo Yuanbin Chen Xiongjun Zhang Lanqin Liu Donghui Lin Zhao Dang Yong Xiang Xuewei Deng | 2016 | High Power Laser Science and Engineering2016，4，3： | 13 |
| 6 | Laser performance upgrade for precise ICF experiment in SG-Ⅲ laser facility显示文摘The SG-Ⅲlaser facility(SG-Ⅲ)is the largest laser driver for inertial confinement fusion(ICF)researches in China,which has 48 beamlines and can deliver 180 kJ ultraviolet laser energy in 3 ns.In order to meet the requirements of precise physics experiments,some new functionalities need to be added to SG-Ⅲand some intrinsic laser performances need upgrade.So at the end of SG-Ⅲ's engineering construction,the 2-year laser performance upgrade project started.This paper will introduce the newly added functionalities and the latest laser performance of SG-Ⅲ.With these function extensions and performance upgrade,SG-Ⅲis now fully prepared for precise ICF experiments and solidly paves the way towards fusion ignition. | Wanguo Zheng Xiaofeng Wei Qihua Zhu Feng Jing Dongxia Hu Xiaodong Yuan Wanjun Dai Wei Zhou Fang Wang Dangpeng Xu Xudong Xie Bin Feng Zhitao Peng Liangfu Guo Yuanbin Chen Xiongjun Zhang Lanqin Liu Donghui Lin Zhao Dang Yong Xiang Rui Zhang Fang Wang Huaiting Jia Xuewei Deng | 2017 | Matter and Radiation at Extremes2017，2，5： | 13 |
| 7 | Optimization Strategy Based on Deep Reinforcement Learning for Home Energy Management显示文摘With the development of a smart grid and smart home,massive amounts of data can be made available,providing the basis for algorithm training in artificial intelligence applications.These continuous improving conditions are expected to enable the home energy management system(HEMS)to cope with the increasing complexities and uncertainties in the enduser side of the power grid system.In this paper,a home energy management optimization strategy is proposed based on deep Q-learning(DQN)and double deep Q-learning(DDQN)to perform scheduling of home energy appliances.The applied algorithms are model-free and can help the customers reduce electricity consumption by taking a series of actions in response to a dynamic environment.In the test,the DDQN is more appropriate for minimizing the cost in a HEMS compared to DQN.In the process of method implementation,the generalization and reward setting of the algorithms are discussed and analyzed in detail.The results of this method are compared with those of Particle Swarm Optimization(PSO)to validate the performance of the proposed algorithm.The effectiveness of applied data-driven methods is validated by using a real-world database combined with the household energy storage model. | Yuankun Liu Dongxia Zhang Hoay Beng Gooi | 2020 | CSEE Journal of Power and Energy Systems2020，6，3： | 9 |
| 8 | Small non-coding RNAs transfer through mammalian placenta and directly regulate fetal gene expression显示文摘 | Jing Li Yujing Zhang Dameng Li Yuchen Liu Danping Chu Xiaohong Jiang Dongxia Hou Ke Zen Chen-Yu zhang | 2015 | Protein & Cell2015，6，6： | 9 |
| 9 | Curative effect of scraping therapies on lumbar muscle strain显示文摘OBJECTIVE:To explore factors influencing the curative effect of scraping therapies (at acupoints or along channels) and to determine the relationship of scraping site and strength to curative effect. METHODS: Two hundred and ten patients with lumbar muscle strain were divided into five groups with 42 patients each.The 'scraping therapy at acupoint until appearance of skin eruptions' and 'scraping therapy along channel until appearance of skin eruptions' groups were treated with a 4-daycourse. The 'scraping therapy at acupoint without appearance of skin eruptions', 'scraping therapy along channel without appearance of skin eruptions', and acupuncture groups were treated with a 2-day course.The five groups were treated with seven courses. The visual analog scale (VAS), oswestry disability index (ODI), and lumbago scores were recorded in the five groups before treatment, after each treatment, and in follow-up visits one month and three months after treatment. RESULTS: VAS, ODI, and lumbago scores after treatment improved in the five groups (P<0.01). There was a statistical difference (P<0.01) in the change of VAS scores by appearance of skin eruptions and scraping site. CONCLUSION: Scraping therapy can effectively alleviate lumbago symptoms. The appearance of skin eruptions and scraping therapy along channels can enhance the curative effect of scraping therapy. | Yingying Wang Li Yang Jinsheng Yang Jinhong Yang Zhibin Liu Feng Chen Dongxia Liu Haiguang Yuan Liang Wang | 2013 | Journal of Traditional Chinese Medicine2013，33，4： | 7 |
| 10 | The lightning activities in super typhoons over the Northwest Pacific显示文摘The spatial and temporal characteristics of lightning activities have been studied in seven super typhoons from 2005 to 2008 over the Northwest Pacific, using data from the World Wide Lightning Location Network (WWLLN). The results indicated that there were three distinct lightning flash regions in mature typhoon, a significant maximum in the eyewall regions (20-80 km from the center), a minimum from 80-200 km, and a strong maximum in the outer rainbands (out of 200 km from the center). The lightning flashes in the outer rainbands were much more than those in the inner rainbands, and less than 1% of flashes occurred within 100 km of the center. Each typhoon produced eyewall lightning outbreak during the periods of its intensification, usually several hours prior to its maximum intensity, indicating that lightning activity might be used as a proxy of intensification of super typhoon. Little lightning occurred near the center after landing of the typhoon. | PAN LunXiang QIE XiuShu LIU DongXia WANG DongFang YANG Jing | 2010 | Science China Earth Sciences2010，53，8： | 7 |
| 11 | Investigating Lightning Characteristics through a Supercell Storm by Comprehensive Coordinated Observations over North China显示文摘Electrical characteristics of an isolated supercell storm observed on 13 June 2014 over Beijing were investigated using lightning data obtained from the Beijing Lightning Network,radar reflectivity,and hydrometeor retrievals during the 6-h lifetime.Positive cloud-to-ground(+CG)lightning took a high percentage of CG lightning.Before and during a hail event,+CG lightning was more frequent than negative cloud-to-ground(-CG)lightning,except that+CG lightning took a high percentage at the beginning and in the dissipating stage.After the hail event ended,-CG lightning dominated and reached its maximum value.An analysis of hydrometeors retrieved by X-band polarimetric radar revealed that the discharge concentrated in the convective region with graupel particles and hailstones,whereas graupel,snow and ice crystals in the stratiform region.Lightning radiation sources were located mainly in the convective region,some of which were distributed along a gradient of radar reflectivity from the convective region to the stratiform region.The indication is that the supercell demonstrated an inverted tripole charge structure before the hail event,which converted to a normal tripole structure after the hail event. | Dongxia LIU Xiushu QIE Yichen CHEN Zhuling SUN Shanfeng YUAN | 2020 | Advances in Atmospheric Sciences2020，37，8： | 4 |
| 12 | Correlation between Expression of P38 MAPK-Signaling and uPA in Breast Cancer显示文摘OBJECTIVE To study the expression of phosphorylated p38 mitogen-activated protein kinase(p-p38)and uPA and the correlation of their expression with breast cancer clinicopathological characteristics,and to investigate the role of the p38MAPK-signaling pathway in regulating uPA expression in breast cancer cells. METHODS Immunohistochemistry(S-P) was used to test the expression of p-p38 and uPA in 60 specimens of breast cancer tissues.Western blots were adopted to detect expression of the p-p38 and uPA proteins in MDA-MB-231 and MCF-7 breast cancer cells,and uPA expression a er treatment with SB203580,a specific inhibitor of p38 MAPK. RESULTS The positive rate of the p-p38 protein and uPA protein expression in the breast cancer tissues was 56.7% and 60.0%,respectively.The expression of p-p38 was positively related to the expression of uPA(r=0.316,P<0.05).The expression of p-p38 and uPA was related to lymph node metastas is and the TNM stage(P<0.05),but it was not related to the patient’s age or tumor size(P>0.05).The expression of p-p38 and uPA in MDA-MB-231 cells was higher than that in MCF-7 cells.SB203580 inhibited the p38 MAPK pathway and reduced uPA protein expression. CONCLUSION The p38 MAPK-signaling pathway promotes breast cancer malignant progression by up-regulating uPA expression,and it may be an important process in breast cancer invasion and metastasis. | Yanchun Han Luying Liu Dongxia Yan Guihua Wang | 2008 | Chinese Journal of Clinical Oncology2008，5，3： | 4 |
| 13 | ATP-binding cassette transporter enhances tolerance to DDT in Tetrahymena显示文摘The reuse of dichlorodiphenyltrichloroethane(DDT) as an indoor residual spray was permitted by the World Health Organization in 2007, and approximately 14 countries still use DDT to control disease vectors. The extensive exposure of insects to DDT has resulted in the emergence of DDT resistance, especially in mosquitoes, and the mechanism for this resistance in mosquitoes has been widely reported. Spraying can also introduce DDT directly into surface water, and DDT can subsequently accumulate in microorganisms, but the mechanism for the resistance to DDT degradation in microorganisms is unclear. Using whole-genome microarray analysis, we detected an abcb15 gene that was up-regulated in a specific manner by DDT treatment in T. thermophile. The deduced ABCB15 peptide sequence had two transmembrane domains(TMDs) and two nucleotide-binding domains(NBDs) to form the structure TMD-NBD-TMD-NBD, and each NBD contained three conserved motifs: Walker-A, C-loop, and Walker-B, which indicated the T. thermophila abcb15 was a typical ABC transporter gene. The expression of ABCB15 fused with a C-terminal green fluorescent protein was found to be on the periphery of the cell, suggesting that ABCB15 was a membrane pump protein. In addition, cells with abcb15 partially knocked down(abcb15-KD) grew slower than wild-type cells in the presence of 256 mg L-1 DDT, indicating the tolerance of abcb15-KD strain to DDT exposure was decreased. Thus, we suggest that in Tetrahymena, the membrane pump protein encoded by ABCT gene abcb15 can enhance the tolerance to DDT and protect cells from this exogenous toxin by efficiently pumping it to the extracellular space. | NING YingZhi DANG Huai LIU GuangLong XIONG Jie YUAN DongXia FENG LiFang MIAO Wei | 2015 | Science China(Life Sciences)2015，58，3： | 3 |
| 14 | Progress in octahedral spherical hohlraum study显示文摘In this paper,we give a review of our theoretical and experimental progress in octahedral spherical hohlraum study.From our theoretical study,the octahedral spherical hohlraums with 6 Laser Entrance Holes(LEHs)of octahedral symmetry have robust high symmetry during the capsule implosion at hohlraum-to-capsule radius ratio larger than 3.7.In addition,the octahedral spherical hohlraums also have potential superiority on low backscattering without supplementary technology.We studied the laser arrangement and constraints of the octahedral spherical hohlraums,and gave a design on the laser arrangement for ignition octahedral hohlraums.As a result,the injection angle of laser beams of 50°-60°was proposed as the optimum candidate range for the octahedral spherical hohlraums.We proposed a novel octahedral spherical hohlraum with cylindrical LEHs and LEH shields,in order to increase the laser coupling efficiency and improve the capsule symmetry and to mitigate the influence of the wall blowoff on laser transport.We studied on the sensitivity of the octahedral spherical hohlraums to random errors and compared the sensitivity among the octahedral spherical hohlraums,the rugby hohlraums and the cylindrical hohlraums,and the results show that the octahedral spherical hohlraums are robust to these random errors while the cylindrical hohlraums are the most sensitive.Up till to now,we have carried out three experiments on the spherical hohlraum with 2 LEHs on Shenguang(SG)laser facilities,including demonstration of improving laser transport by using the cylindrical LEHs in the spherical hohlraums,spherical hohlraum energetics on the SGIII prototype laser facility,and comparisons of laser plasma instabilities between the spherical hohlraums and the cylindrical hohlraums on the SGIII laser facility. | Ke Lan Jie Liu Zhichao Li Xufei Xie Wenyi Huo Yaohua Chen Guoli Ren Chunyang Zheng Dong Yang Sanwei Li Zhiwen Yang Liang Guo Shu Li Mingyu Zhang Xiaoying Han Chuanlei Zhai Lifei Hou Yukun Li Keli Deng Zheng Yuan Xiayu Zhan Feng Wang Guanghui Yuan Haijun Zhang Bobin Jiang Lizhen Huang Wei Zhang Kai Du Runchang Zhao Ping Li Wei Wang Jingqin Su Xuewei Deng Dongxia Hu Wei Zhou Huaiting Jia Yongkun Ding Wanguo Zheng Xiantu He | 2016 | Matter and Radiation at Extremes2016，1，1： | 2 |
| 15 | QM/MM(ABEEM) Study on the Ligand Substitution Processes of Ruthenium(Ill) Complex NAMI-A显示文摘QM combined with ABEEMσπ (atom-bond electronegativity equalization method) fluctuating charge polariza-ble tbrce field [QM/MM(ABEEM)] has been employed to investigate the hydrolysis mechanism of ruthenium(liDcomplex NAMI-A. Eleven possible hydrolysis paths of NAMI-A and its hydrolysates have been unveiled. Struc-tures obtained by QM/MM (ABEEM) method were used to calculate the activation free energy by free energy per-turbation theory. Based on analysis of structures and activation free energies, it is found that the rate of DMSO dis-sociation is faster than that of C1- dissociation in the first step, which is in agreement with experimental results. Hy-drolysates of the first step continue to hydrolyze with lower activation free energies than that of the first hydrolysisstep, but the trans-position CI hydrolysis in the second step needs more time to perform. This can account for ex-perimental phenomenon reasonably. We have simulated further hydrolysis paths of the hydrolysates, then found thatboth CI- dissociation and DMSO dissociation take place in the third hydrolysis step and [RuCl(H20)4(lm)]^2+ is themain solute in aqueous solution after the fourth hydrolysis step. | Hui Li Ting-Ting Sun Chao Zhang Linlin Liu Dongxia Zhao Zhongzhi Yang | 2017 | Chinese Journal of Chemistry2017，35，3： | 2 |
| 16 | Data-driven Decision-making Strategies for Electricity Retailers:A Deep Reinforcement Learning Approach显示文摘With the continuous development of the electricity market,the electricity retailers,as the intermediaries between producers and consumers,have emerged in some of the liberalized electricity markets.Meanwhile,the electricity retailer faces many increasingly significant challenges from the complexities and uncertainties in both the supply and consumption sides.This paper applies a data-driven decision-making strategy via Advantage Actor-Critic(A2C)and Deep Q-Learning(DQN)for the electricity retailers.The retailers’profits and consumers’costs are both taken into account.This study verifies that the applied data-driven methods can handle the decision-making problem as well as promote the profitability of retailers in the electricity market.Furthermore,A2C is more appropriate than DQN in our simulation.The effectiveness of the applied data-driven methods is validated by using real-world data. | Yuankun Liu Dongxia Zhang Hoay Beng Gooi | 2021 | CSEE Journal of Power and Energy Systems2021，7，2： | 2 |
| 17 | Giant Valley Coherence at Room Temperature in 3R WS_(2) with Broken Inversion Symmetry显示文摘Breaking the space-time symmetries in materials can markedly influence their electronic and optical properties.In 3R-stacked transition metal dichalcogenides,the explicitly broken inversion symmetry enables valley-contrasting Berry curvature and quantization of electronic angular momentum,providing an unprecedented platform for valleytronics.Here,we study the valley coherence of 3R WS_(2) large single-crystal with thicknesses ranging from monolayer to octalayer at room temperature.Our measurements demonstrate that both A and B excitons possess robust and thickness-independent valley coherence.The valley coherence of direct A(B)excitons can reach 0.742(0.653)with excitation conditions on resonance with it.Such giant and thickness-independent valley coherence of large single-crystal 3R WS_(2) at room temperature would provide a firm foundation for quantum manipulation of the valley degree of freedom and practical application of valleytronics. | Luojun Du Jian Tang Jing Liang Mengzhou Liao Zhiyan Jia Qinghua Zhang Yanchong Zhao Rong Yang Dongxia Shi Lin Gu Jianyong Xiang Kaihui Liu Zhipei Sun Guangyu Zhang | 2019 | Research2019，，1： | 2 |
| 18 | Activity and se- lectivity differences of external Br6nsted acid sites of single- unit-cell thick and conventional MFI and MWW zeolites 显示文摘 | Liu Dongxia Zhang Xueyi Bhan A | 2014 | MicroporousMesoporousMater2014，200，： | 1 |
| 19 | Understanding the dynamical-microphysical-electrical processes associated with severe thunderstorms over the Beijing metropolitan region显示文摘The Dynamical-microphysical-electrical Processes in Severe Thunderstorms and Lightning Hazards(STORM973)project conducted coordinated comprehensive field observations of thunderstorms in the Beijing metropolitan region(BMR)during the warm season from 2014 to 2018.The aim of the project was to understand how dynamical,microphysical and electrical processes interact in severe thunderstorms in the BMR,and how to assimilate lightning data in numerical weather prediction models to improve severe thunderstorm forecasts.The platforms used in the field campaign included the Beijing Lightning Network(BLNET,consisting of 16 stations),2 X-band dual linear polarimetric Doppler radars,and 4 laser raindrop spectrometers.The collaboration also made use of the China Meteorological Administration’s mesoscale meteorological observation network in the Beijing-Tianjin-Hebei region.Although diverse thunderstorm types were documented,it was found that squall lines and multicell storms were the two major categories of severe thunderstorms with frequent lightning activity and extreme rainfall or unexpected local short-duration heavy rainfall resulting in inundations in the central urban area,influenced by the terrain and environmental conditions.The flash density maximums were found in eastern Changping District,central and eastern Shunyi District,and the central urban area of Beijing,suggesting that the urban heat island effect has a crucial role in the intensification of thunderstorms over Beijing.In addition,the flash rate associated with super thunderstorms can reach hundreds of flashes per minute in the central city regions.The super(5%of the total),strong(35%),and weak(60%)thunderstorms contributed about 37%,56%,and 7%to the total flashes in the BMR,respectively.Owing to the close connection between lightning activity and the thermodynamic and microphysical characteristics of the thunderstorms,the lightning flash rate can be used as an indicator of severe weather events,such as hail and short-duration heavy rainfall.Lightning data can also be assimilated into numerical weather prediction models to help improve the forecasting of severe convection and precipitation at the cloud-resolved scale,through adjusting or correcting the thermodynamic and microphysical parameters of the model. | Xiushu QIE Shanfeng YUAN Zhixiong CHEN Dongfeng WANG Dongxia LIU Mengyu SUN Zhuling SUN Abhay SRIVASTAVA Hongbo ZHANG Jingyu LU Hui XIAO Yongheng BI Liang FENG Ye TIAN Yan XU Rubin JIANG Mingyuan LIU Xian XIAO Shu DUAN Debin SU Chengyun SUN Wenjing XU Yijun ZHANG Gaopeng LU Da-Lin ZHANG Yan YIN Ye YU | 2021 | Science China Earth Sciences2021，64，1： | 1 |
| 20 | Incidence and Risk Factors of the Upper-Limb Musculoskeletal Disorders Among Occupational Groups in Key Industries—China,2018–2021显示文摘What is already known about this topic?The burden of illness and economic losses due to upper-limb work-related musculoskeletal disorders(UL-WMSDs)is high;thus,they have become a major global public health problem.At present,the epidemiological characteristics of UL-WMSDs in China's occupational population are still unknown.What is added by this report?The incidence of UL-WMSDs among key occupational groups in China is 22.5%,with distinct occupational characteristics.What are the implications for public health practice?This study has primarily determined the occurrence and potential risk factors of UL-WMSDs in key industries in China and provided data support for recommending prevention and control of the occurrence of such diseases in key industries in China,and in facilitating the addition into the China’s List of Legal Occupational Diseases. | Ning Jia Meibian Zhang Huadong Zhang Ruijie Ling Yimin Liu Gang Li Yan Yin Hua Shao Hengdong Zhang Bing Qiu Dongxia Li Dayu Wang Qiang Zeng Rugang Wang Jianchao Chen Danying Zhang Liangying Mei Xinglin Fang Yongquan Liu Jixiang Liu Chengyun Zhang Tianlai Li Jun Qi Qing Xu Ying Qu Xueyan Zhang Xin Sun Zhongxu Wang | 2022 | China CDC weekly2022，4，50： | 1 |
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