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| 1 | Stage-progressive distribution pattern of the Lungmachi black graptolitic shales from Guizhou to Chongqing, Central China显示文摘The Lungmachi Formation is widely distributed in Guizhou, Chongqing and the adjacent area. It is important for the study of Silurian biostratigraphy and shale-gas investigation. Based on those biostratigraphically well-studied sections from Guiyang to Huayingshan, we reveal the stage-progressive distribution pattern of the Lungmachi black shales. The distribution of the Lungmachi black shales in the studying area can be subdivided into four geographic belts from the south to the north,reflecting the joint effect of regional and global environmental changes. The graptolite depth zonation model was adopted herein to infer the water depth of major graptolite assemblages from the black shales. The changes in the water depth indicate two major stages. The first stage is named the transgressive distribution stage which ranged from the Persculptograptus persculptus Biozone(LM1, upper Hirnantian) to the Coronograptus cyphus Biozone(LM5, upper Rhuddanian), an interval mostly controlled by global sea-level rise. The second stage, ranging from the Demirastrites triangulatus Biozone(LM6, lower Aeronian) to the Spirograptus guerichi Biozone(LM9, lower Telychian), is named the regressive shrinking stage, during which the black shales were gradually replaced by mixed-facies or carbonate sediments from the south to the north, representing the effects of the persistent uplifting of the Central Guizhou Oldland. | CHEN Xu FAN JunXuan WANG WenHui WANG HongYan NIE HaiKuan SHI XueWen WEN ZhiDong CHEN DongYang LI WenJie | 2017 | Science China Earth Sciences2017，60，6： | 23 |
| 2 | Derivation of water quality criteria for representative water-body pollutants in China显示文摘In this study, toxicological data for zinc (Zn), cadmium (Cd), hexavalent chromium (Cr (VI)), benzene, and nitrobenzene were collected from various databases and publications, screened and then constructed into species sensitivity distribution (SSD) curves. Then water quality criteria (WQC) were derived for protection of the freshwater aquatic life in China against five representative pollutants. The values derived in this study were compared with those issued by the US Environmental Protection Agency and the Chinese national environmental standard for surface water to identify factors underlying the differences. The results showed that the SSD curves for the five pollutants differed significantly, with the examined aquatic species being generally more sensitive to Zn, Cd, and Cr (VI) than benzene and nitrobenzene. The acute WQC were: 48.43 μg L 1 for Zn, 0.4218 μg L 1 for Cd, 45.79 μg L 1 for Cr (VI), 2651 μg L 1 for benzene, and 1426 μg L 1 for nitrobenzene. The chronic WQC were: 20.01 μg L 1 for Zn, 0.2428 μg L 1 for Cd, 14.22 μg L 1 for Cr (VI), 530.2 μg L 1 for benzene, and 286.2 μg L 1 for nitrobenzene. The results of this comparative study of representative pollutants may offer guideline values for future WQC studies for China. | WU FengChang FENG ChengLian ZHANG RuiQing LI YuShuang DU DongYang | 2012 | Science China Earth Sciences2012，55，6： | 16 |
| 3 | SUPERCONVERGENCE ANALYSIS OF THE STABLE CONFORMING RECTANGULAR MIXED FINITE ELEMENTS FOR THE LINEAR ELASTICITY PROBLEM显示文摘在这份报纸,我们基于 Hellinger-Reissner 变化原则考虑线性弹性问题。为压力和排水量和排水量的全球 superconvergence 结果的一个 O (h2 ) 顺序 superclose 性质被采用 Cl 茅 m ent 插值,不可分的身份和适当 postprocessing 技术建立。[从作者抽象] | Dongyang Shi Minghao Li | 2014 | Journal of Computational Mathematics2014，32，2： | 15 |
| 4 | Seismic wave input method for three-dimensional soil-structure dynamic interaction analysis based on the substructure of artificial boundaries显示文摘The method of inputting the seismic wave determines the accuracy of the simulation of soil-structure dynamic interaction. The wave method is a commonly used approach for seismic wave input, which converts the incident wave into equivalent loads on the cutoff boundaries. The wave method has high precision, but the implementation is complicated, especially for three-dimensional models. By deducing another form of equivalent input seismic loads in the fi nite element model, a new seismic wave input method is proposed. In the new method, by imposing the displacements of the free wave fi eld on the nodes of the substructure composed of elements that contain artifi cial boundaries, the equivalent input seismic loads are obtained through dynamic analysis of the substructure. Subsequently, the equivalent input seismic loads are imposed on the artifi cial boundary nodes to complete the seismic wave input and perform seismic analysis of the soil-structure dynamic interaction model. Compared with the wave method, the new method is simplifi ed by avoiding the complex processes of calculating the equivalent input seismic loads. The validity of the new method is verifi ed by the dynamic analysis numerical examples of the homogeneous and layered half space under vertical and oblique incident seismic waves. | Liu Jingbo Tan Hui Bao Xin Wang Dongyang Li Shutao | 2019 | Earthquake Engineering and Engineering Vibration2019，18，4： | 11 |
| 5 | Identification of a novel mutation in POU3F4 for prenatal diagnosis in a Chinese family with X-linked nonsyndromic hearing loss显示文摘We present the clinical and genetic findings for a Chinese family with X-linked non-syndromic hearing loss in which the affected males showed congenital profound sensorineural hearing impairment. In two affected brothers, the computer tomography of temporal bone showed bilateral dilation of the internal auditory canal with fistulous communication between the lateral canal and the basal cochlear turn, which is consistent with the typical DFNX2 phenotype. A missense mutation (c.647G→A) in the POU3F4 gene caused a substitu- tion from glycine to glutamic acid at position 216 (p.G216E), and this mutation was found to consistently cosegregate with the deafness phenotype in the family. The mutation resulted in the loss of function of the POU3F4 by decreasing the affinity between the protein and DNA, as shown in silico by the structural analysis. Prenatal diagnosis of pregnant proband of this family revealed the c.647G→A muta- tion in DNA extracted from the amniotic fluid surrounding the fetus. The appropriate use of genetic testing and prenatal diagnosis plays a key role in reducing the recurrence of genetic defects in high-risk families. | Jianzhong Li Jing Cheng Yanping Lu Yu Lu Airing Chen YiSun Dongyang Kang Xin Zhang Pu Dai Dongyi Han Huijun Yuan | 2010 | Journal of Genetics and Genomics2010，37，12： | 9 |
| 6 | Research and application of methods for effectiveness evaluation of mine cooling system显示文摘Regarding the complexity and inconsistency of results in existing evaluation methods of mine cooling system, this paper clarifies the advantages, disadvantages and application of various mine cooling systems through principle analysis, and divides all the cooling systems into air-cooling, ice-cooling and water-cooling according to the transportation of cold energy. On this basis, the paper proposes a simple and efficient evaluation method for mine cooling system. The first index of this method is the air temperature at point C which is 15 m away from the return wind corner at working face. A cooling system will be judged ineligible if the air temperature at point C is above 30 °C during operation, because in this case, the combustible gases in coal will sharply overflow, inducing gas incidents. Based on the preliminary judgment of the first index, another two evaluation indexes are proposed based on the cooling ability and dehumidification of an airflow volume of 1000 m3/min at point C to evaluate the investment and operation cost of mine cooling system. This evaluation method has already been successfully applied in the cooling system design of Zhangshuanglou coal mine. | Guo Pingye Wang Yanwei Duan Mengmeng Pang Dongyang Li Nan | 2015 | International Journal of Mining Science and Technology2015，25，4： | 7 |
| 7 | Transformative hyaluronic acid-based active targeting supramolecular nanoplatform improves long circulation and enhances cellular uptake in cancer therapy显示文摘Hyaluronic acid(HA) is a natural ligand of tumor-targeted drug delivery systems(DDS) due to the relevant CD44 receptor overexpressed on tumor cell membranes. However, other HA receptors(HARE and LYVE-1) are also overexpressing in the reticuloendothelial system(RES). Therefore,polyethylene glycol(PEG) modification of HA-based DDS is necessary to reduce RES capture.Unfortunately, pegylation remarkably inhibits tumor cellular uptake and endosomal escapement,significantly compromising the in vivo antitumor efficacy. Herein, we developed a Dox-loaded HA-based transformable supramolecular nanoplatform(Dox/HCVBP) to overcome this dilemma. Dox/HCVBP contains a tumor extracellular acidity-sensitive detachable PEG shell achieved by a benzoic imine linkage.The in vitro and in vivo investigations further demonstrated that Dox/HCVBP could be in a 'stealth' state at blood stream for a long circulation time due to the buried HA ligands and the minimized nonspecific interaction by PEG shell. However, it could transform into a 'recognition' state under the tumor acidic microenvironment for efficient tumor cellular uptake due to the direct exposure of active targeting ligand HA following PEG shell detachment. Such a transformative concept provides a promising strategy to resolve the dilemma of natural ligand-based DDS with conflicting two processes of tumor cellular uptake and in vivo nonspecific biodistribution. | Lu Zhong Lu Xu Yanying Liu Qingsong Li Dongyang Zhao Zhenbao Li Huicong Zhang Haotian Zhang Qiming Kan Yongjun Wang Jin Sun Zhonggui He | 2019 | Acta Pharmaceutica Sinica B2019，9，2： | 7 |
| 8 | Mitochondrial DNA A1555G mutation screening using a testing kit method and its significance in preventing aminoglycoside-related hearing loss显示文摘To report a new screening method for mitochondrial DNA 1555A→G mutation and the results of genotype analysis in 19 maternal inherited deafness pedigrees. Method Five hundred and forty-six non-syndromic neuro-sensory hearing loss patients were tested for 1555A→G mutation using a new compact testing kit, which allows clear distinction between wild type and 1555 A→G mutated mtDNAs. Results Nineteen subjects among the 546 patients (3.48%) were found to carry mtDNA A1555G mutation. The results were confirmed by sequencing in an ABI 3100 Avant sequencer. Conclusions Maternal inherited deafness families are a frequently seen in outpatient group. The detection of mtDNA 1555 A→G mutation with a low cost, ready to use detection kit is needed and suitable in China for large scale screening and preventive testing before usage of aminoglycoside antibiotics. | LIU Xin,1 DAI Pu,1* HUANG Deliang,1 YUAN Huijun,1 LI Weiming,1 YU Fei,1 ZHANG Xin,1 KANG Dongyang,1 CAO Juyang,1 YANG Weiyan,1 HAN Dongyi,1 JIN Zhengce2, GUAN Minxin3 1. Department of Otolaryngology, Chinese PLA General Hospital, Beijing, China2. Weihai Aomaier Gene Technological CO.,LTD.,Weihai,Shandong 264200, China.3. Division and Program in Human Genetics and Center for Hearing and Deafness Research, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, USA | 2006 | Journal of Otology2006，1，1： | 7 |
| 9 | Surface-ligand protected reduction on plasmonic tuning of one-dimensional MoO_(3−x)nanobelts for solar steam generation显示文摘Sub-stoichiometric MoO_(3−x)nanostructures with plasmonic absorption via creating oxygen vacancies have attracted extensive attentions for many intriguing applications.However,the synthesis of one-dimensional(1D)plasmonic MoO_(3−x)nanostructures with widely tunable plasmonic absorption has remained a significant challenge because of their serious morphological destruction and phase change with increasing the concentration of oxygen vacancies.Here we demonstrate a surface-ligand protected reduction strategy for the synthesis of 1D MoO_(3−x)nanobelts with tunable plasmonic absorption in a wide wavelength range from 200 to 2,500 nm.Polyethylene glycol(PEG-400)is used as both the reductant to produce oxygen vacancies and the surface protected ligands to maintain 1D morphology during the formation process of MoO_(3−x)nanobelts,enabling the widely tunable plasmonic absorption.Owing to their broad plasmonic absorption and unique 1D nanostructure,we further demonstrate the application of 1D MoO_(3−x)nanobelts as photothermal film for interfacial solar evaporator.The surface-ligand protected reduction strategy provides a new avenue for the developing plasmonic semiconductor oxides with maintained particle morphology and thus enriching their wide applications. | Xindian Li Dongyang Wang Yun Zhang Luntao Liu Wenshou Wang | 2020 | Nano Research2020，13，11： | 4 |
| 10 | Rotation Angle Control Strategy for Telescopic Flexible Manipulator Based on a Combination of Fuzzy Adjustment and RBF Neural Network显示文摘The length of fexible manipulators with a telescopic arm alters during movement.The dynamic parameters of telescopic fexible manipulators exhibit signifcant time-varying characteristics owing to variations in length.With an increase in the manipulators’length,the nonlinear terms caused by fexibility in the manipulators’dynamic equations cannot be ignored.The time-varying characteristics and nonlinear terms of telescopic fexible manipulators cause fuctuations in rotation angles,which afect the operation accuracy of end-efectors.In this study,a control strategy based on a combination of fuzzy adjustment and an RBF neural network is utilized to improve the control accuracy of fexible telescopic manipulators.First,the dynamic equation of the manipulators is established using the assumed mode method and Lagrange’s principle,and the infuence of nonlinear terms is analyzed.Subsequently,a combined control strategy is proposed to suppress the fuctuation of the rotation angle in telescopic fexible manipulators.The variation ranges of the feedforward PD controller parameters are determined by the pole placement strategy and length of the manipulators.Fuzzy rules are utilized to adjust the controller parameters in real-time.The RBF neural network is utilized to identify and compensate the uncertain part of the dynamic model of the fexible manipulators.The uncertain part comprises time-varying parameters and nonlinear terms.Finally,numerical simulations and prototype experiments prove the efectiveness of the combined control strategy.The results prove that the proposed control strategy has a smaller standard deviation of errors.Therefore,the combined control strategy is more suitable for telescopic fexible manipulators,which can efectively improve the control accuracy of rotation angles. | Dongyang Shang Xiaopeng Li Meng Yin Fanjie Li Bangchun Wen | 2022 | Chinese Journal of Mechanical Engineering2022，35，4： | 4 |
| 11 | Optimal dispatching method for integrated energy system based on robust economic model predictive control considering source-load power interval prediction显示文摘Effective source-load prediction and reasonable dispatching are crucial to realize the economic and reliable operations of integrated energy systems(IESs).They can overcome the challenges introduced by the uncertainties of new energies and various types of loads in the IES.Accordingly,a robust optimal dispatching method for the IES based on a robust economic model predictive control(REMPC)strategy considering source-load power interval prediction is proposed.First,an operation model of the IES is established,and an interval prediction model based on the bidirectional long short-term memory network optimized by beetle antenna search and bootstrap is formulated and applied to predict the photovoltaic power and the cooling,heating,and electrical loads.Then,an optimal dispatching scheme based on REMPC is devised for the IES.The source-load interval prediction results are used to improve the robustness of the REPMC and reduce the influence of source-load uncertainties on dispatching.An actual IES case is selected to conduct simulations;the results show that compared with other prediction techniques,the proposed method has higher prediction interval coverage probability and prediction interval normalized averaged width.Moreover,the operational cost of the IES is decreased by the REMPC strategy.With the devised dispatching scheme,the ability of the IES to handle the dispatching risk caused by prediction errors is enhanced.Improved dispatching robustness and operational economy are also achieved. | Yang Yu Jiali Li Dongyang Chen | 2022 | Global Energy Interconnection2022，5，5： | 3 |
| 12 | Insight into selective removal of copper from high-concentration nickel solutions with XPS and DFT:New technique to prepare 5N-nickel with chelating resin显示文摘An efficient and profitable separation process was proposed to prepare 5N(the purity of the metal solution reaches 99.999%) high-purity nickel from 3N nickel-solutions using Purolite S984. The adsorption performance of this superior resin, especially its selectivity for metal ions,was explored quantitatively. The maximum adsorption capacity for copper was 2.286 mmol/g calculated by the Langmuir model, which was twice as large as that for nickel. In the binary systems, the adsorption capacity for nickel was decreased by 45%, indicating direct competition for the active sites. The infinite separation factor for copper versus nickel exceeded 300, revealing the feasibility of preparing5N-level high-purity nickel solutions, which was further verified using the 800 BV(bed volume) effluent in the column dynamic process.According to the cost–benefit analysis, purification contributed to a profit of approximately 60,000 USD per cycle, and the investment return period was less than 1/3 years. Density functional theory analysis confirmed that four nitrogen atoms would be involved in the coordination complex and thus a structure involving two five-membered rings could be achieved. The X-ray photoelectron spectra confirmed the involvement of nitrogen atoms,implying a coordination ratio of approximately 1:1. | Xuewen Tao Fuqiang Liu Zhiping Bai Dongyang Wei Xiaopeng Zhang Junfei Wang Jie Gao Xiaowen Sun Baohua Li Chenghui Li Aimin Li | 2016 | Journal of Environmental Sciences2016，28，10： | 3 |
| 13 | Numerical study on dynamic mechanism of brain volume and shear deformation under blast loading显示文摘Blast-induced traumatic brain injury(b-TBI)is a kind of significant injury to soldiers in the current military conflicts.However,the mechanism of b-TBI has not been well understood,and even there are some contradictory conclusions.It is crucial to reveal the dynamic mechanism of brain volume and shear deformations under blast loading for better understanding of b-TBI.In this paper,the numerical simulation method is adopted to carry out comprehensive and in-depth researches on this issue for the first time.Based on the coupled Eulerian-Lagrangian method,the fluid-structure coupling model of the blast wave and human head is developed to simulate two situations,namely the head subjected to the frontal and lateral impacts.The simulation results are analyzed to obtain the underlying dynamic mechanisms of brain deformation.The brain volume deformation is dominated by the local bending vibration of the skull,and the corresponding frequency for the forehead skull under the frontal impact and the lateral skull faced to the lateral impact is as high as 8 kHz and 5 kHz,respectively.This leads to the high-frequency fluctuation of brain pressure and the large pressure gradient along the skull,totally different from the dynamic response of brain under head collisions.While the brain shear deformation mainly depends on the relative tangential displacement between the skull and brain and the anatomical structure of inner skull,being not related to the brain pressure and its gradient.By further comparing the medical statistics,it is inferred that diffuse axonal injury and brain contusion,the two most common types of b-TBI,are mainly attributed to brain shear deformations.And the von Mises stress can be adopted as the indicator for these two brain injuries.This study can provide theoretical guidance for the diagnosis of b-TBI and the development of protective equipment. | Zhijie Li Zhibo Du Xiaochuan You Zhanli Liu Jian Cheng Chengcheng Luo Dongyang Chu Shaowu Ning Yue Kang Ce Yang Zhuo Zhuang | 2019 | Acta Mechanica Sinica2019，35，5： | 3 |
| 14 | Super-resolution of geosynchronous synthetic aperture radar images using dialectical GANs显示文摘Dear editor,The concept of geosynchronous synthetic aperture radar (GEO SAR) system was conceived in an effort to realize a quick observation of emergency disasters (e.g., landslides and earthquakes)[1].The novel GEO SAR system has the significant advantages of short-revisit time and large coverage and facilitates the nearly continuous observation of target regions, unlike the currently operatinglow earth orbit (LEO) SARs [2]. | Yuanhao LI Dongyang AO Corneliu Octavian DUMITRU Cheng HU Mihai DATCU | 2019 | Science China(Information Sciences)2019，62，10： | 3 |
| 15 | NONCONFORMING FINITE ELEMENT PENALTY METHOD FOR STOKES EQUATION显示文摘NONCONFORMINGFINITEELEMENTPENALTYMETHODFORSTOKESEQUATIONSHIDONGYANG,FENGWEIBINGANDLIKAITAIAbstract.aspecialpenaltymethodispre... | SHI DONGYANG, FENG WEIBING AND LI KAITAI | 1998 | Applied Mathematics(A Journal of Chinese Universities)1998，13，1： | 3 |
| 16 | A scientometric review of biochar preparation research from 2006 to 2019显示文摘Biochar is the carbon-rich product obtained from the thermochemical conversion of biomass under oxygen-limited condi-tions.Preparation methods contribute to biochar properties,which are widely concerned in the agronomic and environmental benefits of agro-ecosystems.This research aims to use bibliometrics methods to comprehensively and objectively analyze the research trends in the global biochar production field from 2006 to 2019 based on the Web of Science Core Collection database.The results showed that 1434 papers related to biochar preparation were published,which gradually increased each year.The research topics were diversified,which were mainly divided into“Environmental Sciences and Ecology,”“Engineering”and“Agriculture”.Moreover,Bioresource Technology was the most published journal contained biochar preparation.Authors from China had the most publications,followed by the US,Australia and the UK.Meanwhile,Yong Sik Ok from Korea University contributed most of the publications and had the highest H-index.Keywords analysis indicated that biochar preparation by pyrolysis was a current hotspot,of which microwave and hydrothermal were a future research trend.Besides,gasification would be used to develop new biomass energy.Biochar has the characteristics of high pH,high specific surface area,high carbon content,and rich functional groups.It is mainly used in soil improvement,water pollutant adsorption,carbon sequestration and emission reduction,and energy storage materials,etc.Furthermore,raw materials,pyrolysis temperature and pyrolysis time will also affect its characteristics and applications.It is expected that this study may provide insight into the future research interests regarding biochar preparation. | Yuxin Jiao Dongyang Li Ming Wang Tiancheng Gong Mengyang Sun Tianxue Yang | 2021 | Biochar2021，3，3： | 3 |
| 17 | Two kinds of ketoprofen enteric gel beads(CA and CS-SA) using biopolymer alginate显示文摘To obtain expected rapid-release and sustained-release of ketoprofen gel beads, this paper adopted biopolymer alginate to prepare alginate beads and chitosan-alginate gel beads. Formulation factors were investigated and optimized by the single factor test. The release of ketoprofen from calcium alginate gel beads in pH 1.0 hydrochloric acid solution was less than 10% during 2 h, then in pH6.8 was about 95% during 45 min, which met the requirements of rapid-release preparations. However, the drug release of chitosan-alginate gel beads in pH1.0 was less than 5% during 2 h, then in pH6.8 was about 50% during 6 h and reached more than 95% during 12 h, which had a good sustained-release behavior. In addition, the release kinetics of keteprofen from the calcium alginate gel beads fitted well with the Korsmeyer–Peppas model and followed a case-II transport mechanism. However, the release of keteprofen from the chitosan-alginate gel beads exhibited a non-Fickian mechanism and based on the mixed mechanisms of diffusion and polymer relaxation from chitosanalginate beads. In a word, alginate gel beads of ketoprofen were instant analgesic, while chitosan-alginate gel beads could control the release of ketoprofen during gastrointestinal tract and prolong the drug's action time. | Bingchao Cheng Dongyang Li Qiye Huo Qianqian Zhao Qi Lan Mengsuo Cui Weisan Pan Xinggang Yang | 2018 | Asian Journal of Pharmaceutical Sciences2018，13，2： | 2 |
| 18 | Joint Dynamic Clustering and User Scheduling for Downlink Cloud Radio Access Network with Limited Feedback显示文摘In limited feedback-based CloudRAN(C-RAN) systems,the inter-cluster and intra-cluster interference together with the quantification error can seriously deteriorates the system spectral efficiency.We,in this paper,propose an efficient three-phase framework and corresponding algorithms for dealing with this problem.Firstly,a greedy scheduling algorithm based on the lower bound of the ergodic rate is performed for generating an elementary cluster in the first phase.And then the elementary cluster is divided into many small clusters according to the following proposed algorithms based on the short term instantaneous information in the second phase.In the end,based on the limited feedback two zero-forcing(ZF) precoding strategies are adopted for reducing the intra-cluster interference in the third phase.The provided Monte Carlo simulations show the effectiveness of our proposed algorithms in the respect of system spectral efficiency and average user rate. | XU Dongyang REN Pinyi DU Qinghe SUN Li | 2015 | China Communications2015，12，12： | 2 |
| 19 | Salivary microbiota may predict the presence of esophageal squamous cell carcinoma显示文摘The aim is to explore the predictive value of salivary bacteria for the presence of esophageal squamous cell carcinoma (ESCC). Saliva samples were obtained from 178 patients with ESCC and 101 healthy controls, and allocated to screening and verification cohorts, respectively. In the screening phase, after saliva DNA was extracted, 16S rRNA V4 regions of salivary bacteria were amplified by polymerase chain reaction (PCR) with high-throughput sequencing. Highly expressed target bacteria were screened by Operational Taxonomic Units clustering, species annotation and microbial diversity assessment. In the verification phase, the expression levels of target bacteria identified in the screening phase were verified by absolute quantitative PCR (Q-PCR). Receiver operating characteristic (ROC) curves were plotted to investigate the predictive value of target salivary bacteria. LEfSe analysis revealed higher proportions of Fusobacterium, Streptococcus and Porphyromonas, and Q-PCR assay showed significantly higher numbers of Streptococcus salivarius, Fusobacterium nucleatum and Porphyromonas gingivalis in patients with ESCC, when compared with healthy controls (all P < 0.05). The areas under the ROC curves for Streptococcus salivarius, Fusobacterium nucleatum, Porphyromonas gingivalis and the combination of the three bacteria for predicting patients with ESCC were 69%, 56.5%, 61.8% and 76.4%, respectively. The sensitivities corresponding to cutoff value were 69.3%, 22.7%, 35.2% and 86.4%, respectively, and the matched specificity were 78.4%, 96.1%, 90.2% and 58.8%, respectively. These highly expressed Streptococcus salivarius, Fusobacterium nucleatum and Porphyromonas gingivalis in the saliva, alone or in combination, indicate their predictive value for ESCC. | Junmin Wei Ruifeng Li Yanxian Lu Fan Meng Bohong Xian Xiaorong Lai Xiayi Lin Yu Deng Dongyang Yang Huabin Zhang Liangfang Li Xiaosong Ben Guibin Qiao Wanwei Liu Zijun Li | 2022 | Genes & Diseases2022，9，4： | 2 |
| 20 | A Hg(Ⅱ)-specific probe for imaging application in living systems and quantitative analysis in environmental/food samples显示文摘Mercury ions are highly toxic and can accumulate along food chains in water,soil,crops and animals.Effective detection of mercury ions in various media is of great significance for maintaining the ecological environment and protecting people's health.In this work,a mercury ions specific fluorescent probe was developed by a simple one-step reaction of commercial substrates of 4-chloro-7-nitro-2,1,3-benzoxadiazole and 1-(2-aminoethyl)-4-methylpiperazine.Investigation on sensing behavior showed that this probe had high sensitivity and selectivity towards mercury ions.Furthermore,this probe could be used as a tool to track the level of mercury ions in living system.In living cells,the probe with green emission emitted a bright red fluorescence when it was bound to mercury ions.In Arabidopsis thaliana,similar red emission could be detected from the root tip and stalk when A.thaliana was grown in culture medium containing mercury ions.The imaging in zebrafish showed that mercury ions were mainly concentrated in the stomach and head of zebrafish.Especially,this probe could be applied in quantitative analysis of mercury ions in tap water,green tea,sea shrimp and soil.This work provided a practical tool for the detection of mercury ions in living systems and quantitative analysis in real samples. | Guangjin Li Jiali Wang Dongyang Li Shenghua Liu Jun Yin Zhibing Lai Guangfu Yang | 2021 | Chinese Chemical Letters2021，32，4： | 2 |
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