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| 1 | Study on gastric cancer blood plasma based on surface-enhanced Raman spectroscopy combined with multivariate analysis显示文摘A surface-enhanced Raman spectroscopy (SERS) method combined with multivariate analysis was developed for non-invasive gastric cancer detection. SERS measurements were performed on two groups of blood plasma samples: one group from 32 gastric patients and the other group from 33 healthy volunteers. Tentative assignments of the Raman bands in the measured SERS spectra suggest interesting cancer-specific biomolecular changes, including an increase in the relative amounts of nucleic acid, collagen, phospholipids and phenylalanine and a decrease in the percentage of amino acids and saccharide in the blood plasma of gastric cancer patients as compared with those of healthy subjects. Principal components analysis (PCA) and linear discriminant analysis (LDA) were employed to develop effective diagnostic algorithms for classification of SERS spectra between normal and cancer plasma with high sensitivity (79.5%) and specificity (91%). A receiver operating characteristic (ROC) curve was employed to assess the accuracy of diagnostic algorithms based on PCA-LDA. The results from this exploratory study demonstrate that SERS plasma analysis combined with PCA-LDA has tremendous potential for the non-invasive detection of gastric cancers. | FENG ShangYuan PAN JianJi WU YanAn LIN Duo CHEN YanPing XI GangQin LIN JuQiang CHEN Rong | 2011 | Science China(Life Sciences)2011，54，9： | 15 |
| 2 | Vertically Aligned Silicon Carbide Nanowires/Boron Nitride Cellulose Aerogel Networks Enhanced Thermal Conductivity and Electromagnetic Absorbing of Epoxy Composites显示文摘With the innovation of microelectronics technology, the heat dissipation problem inside the device will face a severe test. In this work, cellulose aerogel(CA) with highly enhanced thermal conductivity(TC) in vertical planes was successfully obtained by constructing a vertically aligned silicon carbide nanowires(SiC NWs)/boron nitride(BN) network via the ice template-assisted strategy. The unique network structure of SiC NWs connected to BN ensures that the TC of the composite in the vertical direction reaches 2.21 W m^(-1) K^(-1) at a low hybrid filler loading of 16.69 wt%, which was increased by 890% compared to pure epoxy(EP). In addition, relying on unique porous network structure of CA, EP-based composite also showed higher TC than other comparative samples in the horizontal direction. Meanwhile, the composite exhibits good electrically insulating with a volume electrical resistivity about 2.35 × 10^(11) Ω cm and displays excellent electromagnetic wave absorption performance with a minimum reflection loss of-21.5 dB and a wide effective absorption bandwidth(<-10 dB) from 8.8 to 11.6 GHz. Therefore, this work provides a new strategy for manufacturing polymer-based composites with excellent multifunctional performances in microelectronic packaging applications. | Duo Pan Gui Yang Hala MAbo-Dief Jingwen Dong Fengmei Su Chuntai Liu Yifan Li Ben Bin Xu Vignesh Murugadoss Nithesh Naik Salah MEl-Bahy Zeinhom MEl-Bahy Minan Huang Zhanhu Guo | 2022 | Nano-Micro Letters2022，14，7： | 7 |
| 3 | Ultrathin 2D Metal–Organic Framework Nanosheets In situ Interpenetrated by Functional CNTs for Hybrid Energy Storage Device显示文摘The controllable construction of two-dimensional(2D)metal–organic framework(MOF)nanosheets with favorable electrochemical performances is greatly challenging for energy storage.Here,we design an in situ induced growth strategy to construct the ultrathin carboxylated carbon nanotubes(C-CNTs)interpenetrated nickel MOF(Ni-MOF/C-CNTs)nanosheets.The deliberate thickness and specific surface area of novel 2D hybrid nanosheets can be effectively tuned via finely controlling C-CNTs involvement.Due to the unique microstructure,the integrated 2D hybrid nanosheets are endowed with plentiful electroactive sites to promote the electrochemical performances greatly.The prepared Ni-MOF/C-CNTs nanosheets exhibit superior specific capacity of 680 C g^−1 at 1 A g^−1 and good capacity retention.The assembled hybrid device demonstrated the maximum energy density of 44.4 Wh kg^−1 at a power density of 440 W kg^−1.Our novel strategy to construct ultrathin 2D MOF with unique properties can be extended to synthesize various MOF-based functional materials for diverse applications. | Feitian Ran Xueqing Xu Duo Pan Yuyan Liu Yongping Bai Lu Shao | 2020 | Nano-Micro Letters2020，12，4： | 5 |
| 4 | Substantial transition to clean household energy mix in rural China显示文摘The household energy mix has significant impacts on human health and climate,as it contributes greatly to many health-and climate-relevant air pollutants.Compared to the well-established urban energy statistical system,the rural household energy statistical system is incomplete and is often associated with high biases.Via a nationwide investigation,this study revealed high contributions to energy supply from coal and biomass fuels in the rural household energy sector,while electricity comprised∼20%.Stacking(the use of multiple sources of energy)is significant,and the average number of energy types was 2.8 per household.Compared to 2012,the consumption of biomass and coals in 2017 decreased by 45%and 12%,respectively,while the gas consumption amount increased by 204%.Increased gas and decreased coal consumptions were mainly in cooking,while decreased biomass was in both cooking(41%)and heating(59%).The time-sharing fraction of electricity and gases(E&G)for daily cooking grew,reaching 69%in 2017,but for space heating,traditional solid fuels were still dominant,with the national average shared fraction of E&G being only 20%.The non-uniform spatial distribution and the non-linear increase in the fraction of E&G indicated challenges to achieving universal access to modern cooking energy by 2030,particularly in less-developed rural and mountainous areas.In some non-typical heating zones,the increased share of E&G for heating was significant and largely driven by income growth,but in typical heating zones,the time-sharing fraction was<5%and was not significantly increased,except in areas with policy intervention.The intervention policy not only led to dramatic increases in the clean energy fraction for heating but also accelerated the clean cooking transition.Higher income,higher education,younger age,less energy/stove stacking and smaller family size positively impacted the clean energy transition. | Guofeng Shen Rui Xiong Yanlin Tian Zhihan Luo Bahabaike Jiangtulu Wenjun Meng Wei Du Jing Meng Yuanchen Chen Bing Xue Bin Wang Yonghong Duan Jia Duo Fenggui Fan Lei Huang Tianzhen Ju Fenggui Liu Shunxin Li Xianli Liu Yungui Li Mu Wang Ying Nan Bo Pan Yanfang Pan Lizhi Wang Eddy Zeng Chao Zhan Yilin Chen Huizhong Shen Hefa Cheng Shu Tao | 2022 | National Science Review2022，9，7： | 4 |
| 5 | Evolution and protein interactions of AP2 proteins in Brassicaceae: Evidence linking development and environmental responses显示文摘Plants have evolved a large number of transcription factors(TF), which are enriched among duplicate genes,highlighting their roles in complex regulatory networks. The APETALA2/EREBP-like genes constitute a large plant TF family and participate in development and stress responses. To probe the conservation and divergence of AP2/EREBP genes,we analyzed the duplication patterns of this family in Brassicaceae and identified interacting proteins of representative Arabidopsis AP2/EREBP proteins. We found that many AP2/EREBP duplicates generated early in Brassicaceae history were quickly lost, but many others were retained in all tested Brassicaceae species, suggesting early functional divergence followed by persistent conservation. In addition,the sequences of the AP2 domain and exon numbers were highly conserved in rosids. Furthermore, we used 16 A.thaliana AP2/EREBP proteins as baits in yeast screens and identified 1,970 potential AP2/EREBP-interacting proteins,with a small subset of interactions verified in planta. Many AP2 genes also exhibit reduced expression in an antherdefective mutant, providing a possible link to developmental regulation. The putative AP2-interacting proteins participate in many functions in development and stress responses,including photomorphogenesis, flower development, pathogenesis, drought and cold responses, abscisic acid and auxin signaling. Our results present the AP2/EREBP evolution patterns in Brassicaceae, and support a proposed interaction network of AP2/EREBP proteins and their putative interacting proteins for further study. | Liping Zeng Yue Yin Chenjiang You Qianli Pan Duo Xu Taijie Jin Bailong Zhang Hong Ma | 2016 | Journal of Integrative Plant Biology2016，58，6： | 3 |
| 6 | Synthesis and characterization of non-symmetrical liquid crystals containing a cholesteryl ester moiety显示文摘在这篇论文,一系列 chiral 作为 chiral 实体和联本基由 cholesteryl 酉旨一半组成的非对称的液体晶体(nBA-chol ) 有不同终端烷基链的芳香的核心被综合了并且为他们的液体调查了水晶的性质。在阶段转变温度上并且在 chiral 液体晶体的温度依赖者沥青长度上的终端烷基链的甲又单位的数字的效果被学习了。长终端烷基链趋于展出近晶的 A 中央阶段。chiral 液体晶体的 cholesteric 中央阶段的沥青长度与增加温度并且与分别地在终端烷基链增加甲又单位的数字减少。 | Duo Wei Zhang Wei Huang Guo Hui Pan Wan Li He Yu Bo Cao Jin Bao Guo Hui Cao Huai Yang | 2009 | Chinese Chemical Letters2009，20，5： | 3 |
| 7 | Faraday anomalous dispersion optical filter at 133Cs weak 459 nm transition显示文摘A 459 nm Faraday anomalous dispersion optical filter(FADOF) working at the side wings of the cesium6S1∕2→ 7P1∕2transition with weak oscillator strength is achieved. The transmittance of the higher side wing reaches 98% at a temperature of 179°C and magnetic field above 323 G. The experimental results coincide with the theoretical predictions in 1982 and 1995, which were not realized in experiments for over three decades. Due to its high transmittance, high accuracy, and narrow linewidth, the 459 nm FADOF can be applied in underwater optical communications, the building of active optical clocks, and laser frequency stabilization in active optical clocks. | Xiaobo Xue Duo Pan Xiaogang Zhang Bin Luo Jingbiao Chen Hong Guo | 2015 | Photonics Research2015，3，5： | 2 |
| 8 | Preparation of Mg,N-co-doped lignin adsorbents for enhanced selectivity and high adsorption capacity of As(Ⅴ) from wastewater显示文摘Among various environmental problems,water pollution has drawn more and more attention.To develop an adsorbent with enhanced selectivity and high capacity for As(V)oxyanion,a novel lignin-based adsorbent was prepared by doping with N and modifying with Mg^(2+),using thiethylenetetramine(TETA)and MgCl_(2) as the source of N and Mg^(2+),respectively.N-doped lignin(NL)shows a high selectivity for As(Ⅴ),which is further enhanced by modifying with Mg^(2+)(MNL).MNL shows an excellent reusability.The adsorption isotherms and kinetics of MNL for As(Ⅴ)follow Langmuir isotherms model and pseudo-second-order kinetics model,respectively.The adsorption of MNL for As(Ⅴ)achieved a maximum adsorption capacity of 687.46 mg g^(−1) and the equilibrium was established within 30 min.This study offers a novel idea on the recycle of the waste of paper industry and provides a new technology for As(Ⅴ)adsorption from wastewater. | Xiaofeng Shi Junmao Hong Chao Wang Sifang Kong Junhua Li Duo Pan Jing Lin Qinglong Jiang Zhanhu Guo | 2021 | Particuology2021，19，5： | 2 |
| 9 | Zwitterionic glycine modified Fe/Mg-layered double hydroxides for highly selective and efficient removal of oxyanions from polluted water显示文摘Zwitterionic glycine was employed to modify Fe/Mg-layered double hydroxides(LDH)to realize an GFe/Mg-LDH adsorbent with high adsorption capacities of oxygen-containing anions including As(Ⅴ),P(Ⅴ)and Cr(Ⅵ).When the Fe/Mg mole ratio was 0.02 mol/0.02 mol,the G-Fe/Mg-LDH has a good adsorption performance.The optimum adsorption pH value of G-Fe/Mg-LDH for oxygen-containing anions was 6.The selectivity of three oxygen-containing anions was Cr(Ⅵ) | Xiaofeng Shi Chao Wang Jiaoxia Zhang Li Guo Jing Lin Duo Pan Juying Zhou Jincheng Fan Tao Ding Zhanhu Guo | 2020 | Journal of Materials Science & Technology2020，47，16： | 2 |
| 10 | Frequent RNF43 mutation contributes to moderate activation of Wnt signaling in colorectal signet-ring cell carcinoma显示文摘Dear Editor,Signet-ring cell carcinoma(SRCC)is a rare subtype of colorectal cancer(CRC)characterized histologically by the accumulation of mucins in the cytoplasm and displacement of nuclei to the cellular periphery,accounting for about 1%CRC(Fig.S1A)(Borger et al.,2007).Compare to common subtypes of CRC,such as adenocarcinoma(AC)and mucinous adenocarcinoma(MAC),SRCC is associated with aggressive behaviors and younger age at presentation(Kang et al.,2005;Sung et al.,2008;Nitsche et al.,2013;Hugen et al.,2014;Inamura et al.,2015).A retrospective analysis of CRC patient's data at Fudan University Shanghai Cancer Center(FUSCC)also indicated a worse overall and disease-free survival of SRCC patients(Fig.S1B and S1C,Table S1). | Yaqi Li Jian Li Renjie Wang Long Zhang Guoxiang Fu Xueying Wang Yebin Wang Chuantao Fang Dandan Zhang Duo Du Xiaoji Ma Mengxue Pan Qiang Guo Xiaoya Xu Xiang Hu Yi Zhou Shaobo Mo Huijun Wang Jianjun Gao Shenglin Huang Yun Liu Sanjun Cai Guoqiang Hua Junjie Peng Fa-Xing Yu | 2020 | Protein & Cell2020，11，4： | 2 |
| 11 | Research progress in rare earths and their composites based electrode materials for supercapacitors显示文摘Supercapacitor is an imminent potential energy storage system,and acts as a booster to the batteries and fuel cells to provide necessary power density.In the last decade,carbon and carbonaceous materials,conducting polymers and transition metal oxide/hydroxide based electrode materials have been made to show a remarkable electrochemical performance.Rare-earth materials have attracted significant research attention as an electrode material for supercapacitor applications based on their physicochemical properties.In this review,rare earth metals,rare earth metal oxides/hydroxides,rare-earth metal chalcogenides,rare-earth metal/carbon composites and rare-earth metal/metal oxide composites based electrode materials are discussed for supercapacitors.We also discuss the energy chemistry of rare-earth metal-based materials.Besides the factors that affect the performance of the electrode materials,their evaluation methods and supercapacitor performances are discussed in details.Finally,the future outlook in rare-earth-based electrode materials is revealed towards its current developments for supercapacitor applications. | Subasri Arunachalam Balakrishnan Kirubasankar Duo Pan Hu Liu Chao Yan Zhanhu Guo Subramania Angaiah | 2020 | Green Energy & Environment2020，5，3： | 2 |
| 12 | In-situ constructing visible light CdS/Cd-MOF photocatalyst with enhanced photodegradation of methylene blue显示文摘Based on high specific surface area,high porosity of metal-organic frameworks(MOFs)and excellent vis-ible light response of CdS,the CdS/Cd-MOF nanocomposites were constructed by in-situ sulfurization to form CdS using Cd-MOF as precursor and the CdS loading was controlled by the dose of thioac-etamide.Under the irradiation of simulated sunlight,the degradation rate of methylene blue(MB)by 10mg MOF/CdS-6(mass ratio of MOF to thioacetamide is 6:1)was 91.9%in 100min,which was higher than that of pure Cd-MOF(62.3%)and pure CdS(67.5%).This is attributed to the larger specific surface area of the composite catalysts,which provides more active sites.Meanwhile,the loading of CdS obvi-ously broadens the light response range of Cd-MOF and improves the utilization of visible light.The Mott-Schottky model experiment shows that the formed type-Ⅱheterojunction between Cd-MOF and CdS can effectively inhibit the recombination of photogenerated electrons and holes.Meanwhile,the photocurrent intensity of MOF/CdS-6 is 8 times and 2.5 times of that of pure Cd-MOF and CdS.In addi-tion,MOF/CdS-6 showed good photocatalytic performance after five cycles,showing excellent stability and reusability. | Cheng Jing Yufei Zhang Junjie Zheng Shengsong Ge Jing Lin Duo Pan Nithesh Naik Zhanhu Guo | 2022 | Particuology2022，20，10： | 1 |
| 13 | Facile fabrication of polyaniline nanotubes using the self-assembly behavior based on the hydrogen bonding: a mechanistic study and application in high-performance electrochemical supercapacitor electrode显示文摘 | Wenling Wu Duo Pan Yanfeng Li Guanghui Zhao Lingyun Jing Suli Chen | 2015 | Electrochimica Acta2015，，： | 1 |
| 14 | Pervaporation Properties of PDMS Membranes for Removal of Benzene from Aqueous Solution: Experimental and Modeling 显示文摘 | Peng Fubing Pan Fusheng Li Duo | 2005 | Chem EngJ2005，114，13： | 1 |
| 15 | Sorption of Th(IV) on Na-bentonite: effects of pH, ionic strength, humic substances and temperature 显示文摘 | Duo qiang Pan Qiao hui Fan Ping Li | 2011 | Chemical Engineering Journal2011，172，23： | 1 |
| 16 | The transmission properties of the metal-coated THz PS tube with grooves 显示文摘 | Wu Pan Tian bo Duo Jun Chen | 2014 | Progress In Electromagnetics Research Letters2014，44，1： | 1 |
| 17 | Efficient Transposition of the Retrotransposon Tnt1 in Cucumber(Cucumis sativus L.)显示文摘Tnt1 is an active retrotransposon originally identified in tobacco(Nicotiana tabacum L.)(Grandbastien et al.,1989),but its transposition activity could be activated through tissue culture in other plant species.The insertions are stable and inheritable in the progeny,which has made it a valuable and versatile tool for developing insertional mutagenesis libraries in several plant species.Here,we explored its utility for mutagenesis in cucumber(Cucumis sativus L.).T_3 Tnt1 transgenic cucumber plants were subjected to tissue culture to regenerate self-pollinated progeny.With PCR and analyses and Southern hybridization,we found regenerated plants maintained the original Tnt1 insertion and created new insertions suggesting characteristic re-transposition activity of Tnt1 during this process.Using genome walking,some flanking sequences of Tnt1 insertions were recovered in regenerated plants.The results demonstrated that Tnt1 could be stably inherited and re-transposable during tissue culture in cucumber and that it is feasible to use for developing an insertional mutagenesis library for cucumber. | ZHANG Qi DU Hui LV Duo XIAO Tingting PAN Jian HE Huanle WANG Gang CAI Run WENG Yiqun PAN Junsong | 2018 | Horticultural Plant Journal2018，4，3： | 0 |
| 18 | An active bacterial anti-adhesion strategy based on directional transportation of bacterial droplets driven by triboelectric nanogenerators显示文摘An active bacterial anti-adhesion strategy based on directional transportation of bacterial droplets driven by a triboelectric nanogenerator(TENG)has not been reported to date,although passive defense approaches can prevent bacterial adhesion by regulating superwetting surfaces combined with incorporated antibacterial substances.Here a triboelectric nanogenerator driving droplet system(TNDDS)was built to drive directional transportation of bacterial droplets to be eliminated,which comprises TENG with periodical frictional Kapton film and aluminum foils and a superhydrophobic driving platform(SDP)with paralleled driving electrodes.The current generated by the TENG triboelectricity is transmitted to the paralleled driving electrodes to form an electric field driving the directional transportation of charged droplets.The critical value of the driven droplet volume on SDP is closely related to the distributed electrodes’distance and width,and the driving distance of droplets is related to the number of electrodes.More crucially,TNDDS can actively drive the charged droplets of prepared triangular silver nanoprisms(Ag NPs)forward and back to mix with and remove a tiny bacterial droplet on an open SDP or in a tiny semi-enclosed channel.Bacteria could be killed by releasing Ag+and effectively removed by TNDDS by regulating the motion direction.Generally,this approach offers a promising application for removing bacteria from material surfaces driven by TENG and opens a new avenue for bacterial anti-adhesion. | Jing Lin Jialin Li Shichang Feng Caiqin Gu Huajian Li Hanqing Lu Fei Hu Duo Pan Ben Bin Xu Zhanhu Guo | 2023 | Nano Research2023，16，1： | 0 |
| 19 | Narrower atomic filter at 422.7 nm based on thermal Ca beam显示文摘So far, the only Ca magneto-optic atomic filters reported are based on a heated Ca cell, and the transmission spectrum obtained is double-peaked with 3 GHz effective passband limited by Doppler broadening. A magneto-optic atomic filter with single-peaked transmission spectrum of sub-Doppler bandwidth based on the thermal Ca atomic beam is firstly experimentally demonstrated. The fast Ca dipole transition(1S0–1P1) at 422.7 nm, which matches a strong solar Fraunhofer line, was utilized. A folded ninebeam traveling wave configuration is employed, and the maximum transmission efficiency is measured to be 7.3 %.A sub-Doppler transmission bandwidth of 590 MHz, much narrower than the 2.2 GHz Doppler width in the heated atomic cell, is obtained for the first time. | Zhichao Xu Xiaobo Xue Duo Pan Xiaogang Zhang Wei Zhuang Jingbiao Chen | 2014 | Chinese Science Bulletin2014，59，28： | 0 |
| 20 | A novel selective ERK1/2 inhibitor,Laxiflorin B,targets EGFR mutation subtypes in non-small-cell lung cancer显示文摘Extracellular regulated protein kinases 1/2(ERK1/2)are key members of multiple signaling pathways,including the ErbB axis.Ectopic ERK1/2 activation contributes to various types of cancer,especially drug resistance to inhibitors of RTK,RAF and MEK,and specific ERK1/2 inhibitors are scarce.In this study,we identified a potential novel covalent ERK inhibitor,Laxiflorin B,which is a herbal compound with anticancer activity.However,Laxiflorin B is present at low levels in herbs;therefore,we adopted a semi-synthetic process for the efficient production of Laxiflorin B to improve the yield.Laxiflorin B induced mitochondria-mediated apoptosis via BAD activation in non-small-cell lung cancer(NSCLC)cells,especially in EGFR mutant subtypes.Transcriptomic analysis suggested that Laxiflorin B inhibits amphiregulin(AREG)and epiregulin(EREG)expression through ERK inhibition,and suppressed the activation of their receptors,ErbBs,via a positive feedback loop.Moreover,mass spectrometry analysis combined with computer simulation revealed that Laxiflorin B binds covalently to Cys-183 in the ATP-binding pocket of ERK1 via the D-ring,and Cys-178 of ERK1 through non-inhibitory binding of the A-ring.In a NSCLC tumor xenograft model in nude mice,Laxiflorin B also exhibited strong tumor suppressive effects with low toxicity and AREG and EREG were identified as biomarkers of Laxiflorin B efficacy.Finally,Laxiflorin B-4,a C-6 analog of Laxiflorin B,exhibited higher binding affinity for ERK1/2 and stronger tumor suppression.These findings provide a new approach to tumor inhibition using natural anticancer compounds. | Cheng-Yao Chiang Min Zhang Junrong Huang Juan Zeng Chunlan Chen Dongmei Pan Heng Yang Tiantian Zhang Min Yang Qiangqiang Han Zou Wang Tian Xiao Yangchao Chen Yongdong Zou Feng Yin Zigang Li Lizhi Zhu Duo Zheng | 2024 | Acta Pharmacologica Sinica2024，45，2： | 0 |
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