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| 1 | Model for end-stage liver disease score versus Child score in predicting the outcome of surgical procedures in patients with cirrhosis显示文摘AIM:To determine factors affecting the outcome of patients with cirrhosis undergoing surgery and to compare the capacities of the Child-Turcotte-Pugh(CTP) and model for end-stage liver disease(MELD)score to predict that outcome. METHODS:We reviewed the charts of 195 patients with cirrhosis who underwent surgery at two teaching hospitals over a five-year period.The combined endpoint of death or hepatic decompensation was considered to be the primary endpoint. RESULTS:Patients who reached the endpoint had a higher MELD score,a higher CTP score and were more likely to have undergone an urgent procedure.Among patients undergoing elective surgical procedures,no statistically significant difference was noted in the mean MELD(12.8±3.9 vs 12.6±4.7,P=0.9)or in the mean CTP(7.6±1.2 vs 7.7±1.7,P=0.8)between patients who reached the endpoint and those who did not.Both mean scores were higher in the patients reaching the endpoint in the case of urgent procedures(MELD:22.4± 8.7 vs 15.2±6.4,P=0.0007;CTP:9.9±1.8 vs 8.5±1.8, P=0.008).The performances of the MELD and CTP scores in predicting the outcome of urgent surgery were only fair,without a significant difference between them (AUC=0.755±0.066 for MELD vs AUC=0.696±0.070 for CTP,P=0.3). CONCLUSION:The CTP and MELD scores performedequally,but only fairly in predicting the outcome of urgent surgical procedures.Larger studies are needed to better define the factors capable of predicting the outcome of elective surgical procedures in patients with cirrhosis. | Maarouf A Hoteit Amaar H Ghazale Andrew J Bain Eli S Rosenberg Kirk A Easley Frank A Anania Robin E Rutherford | 2008 | World Journal of Gastroenterology2008,14,11: | 16 |
| 2 | Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation显示文摘 | D.L Lacey E Timms H.-L Tan M.J Kelley C.R Dunstan T Burgess R Elliott A Colombero G Elliott S Scully H Hsu J Sullivan N Hawkins E Davy C Capparelli A Eli Y.-X Qian S Kaufman I Sarosi V Shalhoub G Senaldi J Guo J Delaney W.J Boyle | 1998 | Cell1998,,2: | 4 |
| 3 | α1-antitrypsin increases interleukin-1 receptor antagonist production during pancreatic islet graft transplantation显示文摘尽管为有类型 1 糖尿病的个人的小岛移植被显示了产出优异的血葡萄糖控制,它为长期的控制仍然保持不适当。这是部分,由于小岛损害和压力,那能导致贝它房间损失。过量 IL-1β 的抑制;活动可能最小化小岛损害,因此保存工作。IL-1 受体对手(IL-1Ra ) , IL-1β 的一个内长的禁止者;,保护小岛免受导致 cytokine 的坏死和 apoptosis 的伤害。因此,在 IL-1β 之间的不平衡;并且 IL-1Ra 可能影响到小岛的 allogeneic 和自体免疫的回答的功课。我们的组以前证明传播丝氨酸朊酶禁止者人 alpha-1-antitrypsin (hAAT ) ,以及 immunomodulatory 活动。在现在的学习,我们寻求了决定是否胰腺的小岛 hAAT 的 allograft 保护的活动被 IL-1Ra 调停感应。我们的结果证明 hAAT 在刺激巨噬细胞在 IL-1Ra 表示导致了 2.04 褶层增加并且 hAAT-pre-treated 小岛接枝在 IL-1Ra 抄本层次展出了 4.851 褶层增加,它与中等煽动性的侧面被联系。出人意料地,从 IL-1Ra-knockout 鼠标被孤立并且在 grafting 前与 hAAT 预先对待进野类型的鼠标的小岛在大概从渗入主机房间被导出的 intragraft IL-1Ra 表示产出增加,当主机的 hAAT 处理不在时的虽然。确实, hAAT-pre-treated 小岛产生了能在有教养的巨噬细胞导致 IL-1Ra 生产的 hAAT 免费的调节媒介。最后,我们证明 hAAT 为 p65 支持了不同 phosphorylation 和原子 translocation 模式,为 IL-1Ra 要求的一个关键抄写因素表示。 | Avishag Abecassis Ronen Schuster Galit Shahaf Eyal Ozeri Ross Green David E Ochayon Peleg Rider Eli C Lewis | 2014 | Cellular & Molecular Immunology2014,11,4: | 2 |
| 4 | Effect of donor–recipient HLA matching at HLA A, B, C, and DRB1 on outcomes after umbilical-cord blood transplantation for leukaemia and myelodysplastic syndrome: a retrospective analysis显示文摘 | Mary Eapen John P Klein Guillermo F Sanz Stephen Spellman Annalisa Ruggeri Claudio Anasetti Maria Brown Richard E Champlin Joan Garcia-Lopez Gareth Hattersely Gesine Koegler Mary J Laughlin Gerard Michel Samir K Nabhan Franklin O Smith Mary M Horowitz Eli | 2011 | Lancet Oncology2011,,13: | 2 |
| 5 | Effect of graft source on unrelated donor haemopoietic stem-cell transplantation in adults with acute leukaemia: a retrospective analysis显示文摘 | Mary Eapen Vanderson Rocha Guillermo Sanz Andromachi Scaradavou Mei-Jie Zhang William Arcese Anne Sirvent Richard E Champlin Nelson Chao Adrian P Gee Luis Isola Mary J Laughlin David I Marks Samir Nabhan Annalisa Ruggeri Robert Soiffer Mary M Horowitz Eli | 2010 | Lancet Oncology2010,,7: | 2 |
| 6 | Expandable proximal femoral nails versus 95 dynamic condylar screw - plates for the treatment of reverse oblique intertrochanteric fractures显示文摘 | ELIS J CHECHIK O MAMAN E | 2012 | Injury2012,43,8: | 1 |
| 7 | Comparison of a new colorimetric assay with the NCCLS broth microdilution method(M27-A) for antifungal drug MIC determination显示文摘 | LI R K ELIE C M CLAYTON G E | 2000 | J Clin Microbiol2000,38,6: | 1 |
| 8 | Advances in meniscal tissue engineering显示文摘 | Eli N Oragui E Khan W | 2011 | Ortop Traumatol Rehabil2011,13,: | 1 |
| 9 | Half-integral spiral phase plates for optical wavelengths 显示文摘 | Oemrawsinghl S S R Elie E R Woerdman J P | 2004 | J Opt A: Pure Appl Opt2004,6,: | 1 |
| 10 | Controllable-stiffness components basedon magnetorheological elastomers 显示文摘 | Ginder J M Nichols M E Elie L D | 2000 | Proceedings of SPIE2000,3985,: | 1 |
| 11 | Electrochemical aspects of copper chemical mechanical planarization (CMP) in peroxide based slurries containing BTA and glycine显示文摘 | Eli Y E Abelev E Starosvetsky D | | 0,,: | 1 |
| 12 | Role of surgery in the treatment of primary pulmonary B-cel lymphoma显示文摘 | Frederic V E Elie F Marc P | | 0,,01: | 1 |
| 13 | High level of burnout in intensivists: prevalence and associated factors 显示文摘 | NATHALIE E ELIE A KARINE B | 2007 | Am J Respir Crit Care Med2007,175,7: | 1 |
| 14 | Controllable stiffness components based on magnetorheological elastomers显示文摘 | Ginder J M Nichols M E Elie L D | 2000 | Smart Structures and Materials2000,,3985: | 1 |
| 15 | Randomized comparison of rescue angioplasty with conservative management of patients with early failure of thrombolysis for acute anterior myocardial infarction显示文摘 | Ribeiro da Silva E Heyndrickx G | 1994 | Circulation1994,90,: | 1 |
| 16 | Ultrasonic processing of enzymes: Effect on enzymatic activity of glucose oxidase 显示文摘 | Elie A G Choi S H Geckeler K E | 2009 | J Mol Catal B: Enzym2009,58,: | 1 |
| 17 | MRI findings in Painful Post-stroke Shoulder显示文摘 | Rajiv RS Sepideh H Elie E | 2009 | Stroke2009,39,6: | 1 |
| 18 | Absence of anti-D alloimmunization in hematologic patients after D-incompatible platelettransfusions显示文摘 | Cid J Ortin X Elies E | 2002 | Transfusion2002,,: | 1 |
| 19 | Role of surgery in the treatment of primary pulmonary B-cell lymphoma显示文摘 | Frederic V E Elie F Marc P | 2007 | Ann Thorac Surg2007,83,: | 1 |
| 20 | Fluticasone induces apoptosis in peripheral T-lymphocytes:a comparison between asthmatic and normal subjects显示文摘 | Elis M Siena L Pace E | 2002 | Eur Respir J2002,19,2: | 1 |