|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | An ensemble method for gene discovery based on DNA microarray data显示文摘The advent of DNA microarray technology has offered the promise of casting new insights onto deciphering secrets of life by monitoring activities of thousands of genes simulta-neously. Current analyses of microarray data focus on precise classification of biological types, for example, tumor versus normal tissues. A further scientific challenging task is to extract dis-ease-relevant genes from the bewildering amounts of raw data, which is one of the most critical themes in the post-genomic era, but it is generally ignored due to lack of an efficient approach. In this paper, we present a novel ensemble method for gene extraction that can be tailored to fulfill multiple biological tasks including (i) precise classification of biological types; (ii) disease gene mining; and (iii) target-driven gene networking. We also give a numerical application for (i) and (ii) using a public microarrary data set and set aside a separate paper to address (iii). | Kathy L. MOSER Eric J. TOPOL | 2004 | Science China(Life Sciences)2004，47，5： | 5 |
| 2 | Coronary Heart Disease/Thrombosis/Myocardial-Infarction: Marked Inflammatory Sequelae to Implantation of Biodegradable and Nonbiodegradable Polymers in Porcine Coronary Arteries显示文摘 | Willem J. van der Giessen A. Michael Lincoff Robert S. Schwartz Heleen M.M. van Beusekom Patrick W. Serruys David R. Jr Holmes Stephen G. Ellis Eric J. Topol | 1996 | Circulation1996，，7： | 1 |
| 3 | Incomplete Inhibition of Thromboxane Biosynthesis by Acetylsalicylic Acid: Determinants and Effect on Cardiovascular Risk显示文摘 | John W. Eikelboom Graeme J. Hankey Jim Thom Deepak L. Bhatt P Gabriel Steg Gilles Montalescot S Claiborne Johnston Steven R. Steinhubl Koon-Hou Mak J Donald Easton Christian Hamm Tingfei Hu Keith A.A. Fox Eric J. Topol | 2008 | Circulation2008，，17： | 1 |
| 4 | Myeloperoxidase-Generated Oxidants Modulate Left Ventricular Remodeling but Not Infarct Size After Myocardial Infarction显示文摘 | Nikolay Vasilyev Timothy Williams Marie-Luise Brennan Samuel Unzek Xiaorong Zhou Jay W. Heinecke Douglas R. Spitz Eric J. Topol Stanley L. Hazen Marc S. Penn | 2005 | Circulation2005，，18： | 1 |
| 5 | Platelet Reactivity and Cardiovascular Outcomes After Percutaneous Coronary Intervention: A Time-Dependent Analysis of the Gauging Responsiveness With a VerifyNow P2Y12 Assay: Impact on Thrombosis and Safety (GRAVITAS) Trial显示文摘 | Matthew J. Price Dominick J. Angiolillo Paul S. Teirstein Elizabeth Lillie Steven V. Manoukian Peter B. Berger Jean-Fran?ois Tanguay Christopher P. Cannon Eric J. Topol | 2011 | Circulation2011，，10： | 1 |
| 6 | Cardiogenic shock complicating acute myocardial infarction: Predictors of death显示文摘 | David Hasdai David R. Holmes Robert M. Califf Trevor D. Thompson Judith S. Hochman Matthias Pfisterer Eric J. Topol | 1999 | American Heart Journal1999，，1： | 1 |
| 7 | Predictors of Outcome in Patients With Acute Coronary Syndromes Without Persistent ST-Segment Elevation: Results From an International Trial of 9461 Patients显示文摘 | Eric Boersma Karen S. Pieper Ewout W. Steyerberg Robert G. Wilcox Wei-Ching Chang Kerry L. Lee K. Martijn Akkerhuis Robert A. Harrington Jaap W. Deckers Paul W. Armstrong A. Michael Lincoff Robert M. Califf Eric J. Topol Maarten L. Simoons | 2000 | Circulation: Journal of the American Heart Association2000，，22： | 1 |
| 8 | Analysis of Risk of Bleeding Complications After Different Doses of Aspirin in 192,036 Patients Enrolled in 31 Randomized Controlled Trials显示文摘 | Victor L. Serebruany Steven R. Steinhubl Peter B. Berger Alex I. Malinin Jeffrey S. Baggish Deepak L. Bhatt Eric J. Topol | 2005 | The American Journal of Cardiology2005，，10： | 1 |
| 9 | Muragntazar对2型糖尿病患者死亡及主要心血管不良事件的影响显示文摘背景:过氧化物酶体增殖物激活受体(peroxisome proliferator-activated receptors,PPARs)是调节基因表达的核转录因子。以两种不同PPAR家族成员(α和γ)为治疗靶点的药物已经在美国开始使用。2005年9月9日,经美国食品与药物管理局(FDA)咨询委员会审查后,第一代PPAR双激动剂muraglitazar以8:1的投票被批准用于2型糖尿病患者的血糖控制。 | Steven E. Nissen Kathy Wolski Eric J. Topol 沈琴(译) 贾伟平(校) | 2006 | 美国医学会杂志(中文版)2006，25，6： | 1 |
| 10 | Multi-allelic haplotype association identifies novel information different from single-SNP analysis: A new protective haplotype in the LRP8 gene is against familial and early-onset CAD and MI显示文摘 | Gong-Qing Shen Domenico Girelli Lin Li Oliviero Olivieri Nicola Martinelli Qiuyun Chen Eric J. Topol Qing K. Wang | 2013 | Gene2013，，： | 1 |
| 11 | Impact of Blood Transfusion on Short- and Long-Term Mortality in Patients With ST-Segment Elevation Myocardial Infarction显示文摘 | Mehdi H. Shishehbor Surabhi Madhwal Vivek Rajagopal Amy Hsu Peter Kelly Hitinder S. Gurm Samir R. Kapadia Michael S. Lauer Eric J. Topol | 2009 | JACC: Cardiovascular Interventions2009，，： | 1 |
| 12 | Risk stratification for patients undergoing nonurgent percutaneous coronary intervention using N-terminal pro–B-type natriuretic peptide: A Clopidogrel for the Reduction of Events During Observation (CREDO) substudy显示文摘 | W.H. Wilson Tang Steven R. Steinhubl Frederick Van Lente Danielle Brennan Ellen McErlean Anjli Maroo Gary S. Francis Eric J. Topol | 2007 | American Heart Journal2007，，1： | 1 |
| 13 | The efficacy and safety of short- and long-term dual antiplatelet therapy in patients with mild or moderate chronic kidney disease: Results from the Clopidogrel for the Reduction of Events During Observation (CREDO) Trial显示文摘 | Patricia J.M. Best Steven R. Steinhubl Peter B. Berger Arijit Dasgupta Danielle M. Brennan Lynda A. Szczech Robert M. Califf Eric J. Topol | 2008 | American Heart Journal2008，，： | 1 |
| 14 | Frequency of stent thrombosis after acute coronary syndromes (from the SYMPHONY and 2nd SYMPHONY trials)显示文摘 | Thaddeus R. Tolleson L.Kristin Newby Robert A. Harrington Manjushri V. Bhapkar Freek W.A. Verheugt Peter B. Berger David J. Moliterno Harvey D. White E.Magnus Ohman Frans Van de Werf Eric J. Topol Robert M. Califf | 2003 | The American Journal of Cardiology2003，，3： | 1 |
| 15 | Celecoxib, a Selective Cyclooxygenase-2 Inhibitor, Decreases Monocyte Chemoattractant Protein-1 Expression and Neointimal Hyperplasia in the Rabbit Atherosclerotic Balloon Injury Model显示文摘 | Kai Wang Khaldoun Tarakji Zhongmin Zhou Ming Zhang Farhad Forudi Xiaorong Zhou Alane T. Koki Mark E. Smith Bradley T. Keller Eric J. Topol A. Michael Lincoff Marc S. Penn | 2005 | Journal of Cardiovascular Pharmacology2005，，1： | 1 |
| 16 | Death Following Creatine Kinase-MB Elevation After Coronary Intervention: Identification of an Early Risk Period: Importance of Creatine Kinase-MB Level, Completeness of Revascularization, Ventricular Function, and Probable Benefit of Statin Therapy显示文摘 | Stephen G. Ellis Derek Chew Albert Chan Patrick L. Whitlow Jakob P. Schneider Eric J. Topol | 2002 | Circulation: Journal of the American Heart Association2002，，10： | 1 |
| 17 | Tissue Factor, the Emerging Link Between Inflammation, Thrombosis, and Vascular Remodeling显示文摘 | Marc S. Penn Eric J. Topol | 2001 | Circulation Research: Journal of the American Heart Association2001，，1： | 1 |
| 18 | Platelet Glycoprotein IIb/IIIa Inhibitors Reduce Mortality in Diabetic Patients With Non–ST-Segment-Elevation Acute Coronary Syndromes显示文摘 | Marco Roffi Derek P. Chew Debabrata Mukherjee Deepak L. Bhatt Jennifer A. White Christopher Heeschen Christian W. Hamm David J. Moliterno Robert M. Califf Harvey D. White Neal S. Kleiman Pierre Théroux Eric J. Topol | 2001 | Circulation: Journal of the American Heart Association2001，，23： | 1 |
| 19 | Sustained ventricular arrhythmias and mortality among patients with acute myocardial infarction: Results from the GUSTO-III trial显示文摘 | Sana M. Al-Khatib Amanda L. Stebbins Robert M. Califf Kerry L. Lee Christopher B. Granger Harvey D. White Paul W. Armstrong Eric J. Topol E.Magnus Ohman | 2003 | American Heart Journal2003，，： | 1 |
| 20 | Coronary Heart Disease/Myocardial Infarction: Predictors of 30-Day Mortality in the Era of Reperfusion for Acute Myocardial Infarction: Results From an International Trial of 41 021 Patients显示文摘 | Kerry L. Lee Lynn H. Woodlief Eric J. Topol W. Douglas Weaver Amadeo Betriu Jacques NA Maarten Simoons Phil Aylward Frans Van de Werf Robert M. Califf | 1995 | Circulation1995，，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员